2001b  Aja et al., 2001b  CART I (55–102)  i.c.v. (3V)  Rat  Ensure liquid diet  ↓ Spontaneous feeding (↓ liquid diet intake and observations of feeding in food restricted animals)—reductions significantly attentuated by aqueduct obstructiona  Alterations in motor behavior (flat-backed and arched-backed postures and movement-associated tremors)—alterations significantly attentuated by aqueduct obstructiona