2001  Zheng et al., 2001  CART I (55–102)  i.c.v. (LV and 4V)  Rat  Sucrose solution or standard chow  ↓ Spontaneous feeding (↓ short-term sucrose intake and ↓ overnight chow intake)—effects more pronounced in 4V compared to LV administration  Alterations in motor behavior (mild movement-associated tremors in part of 4V injected subjects)