2.4.5 Monoamine oxidase B (MAOB) MAOB preferentially metabolizes dopamine, while MAOA preferentially metabolizes serotonin and norepinephrine. Li and colleagues[99] screened exons and the 5’ and 3’ flanking regions of the MAOB gene and found two novel polymorphisms (2276C>T and 2327C>T) that were closely associated with ADHD. However, Jiang conducted a transmission disequilibrium test (TDT) to assess the linkage between a VNTR polymorphism at the MAOA(CA) (n) or MAOB(GT) (n) locus, and found no significant linkage between ADHD and MAOB.[92] 2