Epidemiologic evidence suggests that 30%–90% of asthmatic patients have GERD,17,18 and respiratory symptoms associated with asthma are increased among patients with GERD.19 It is suggested that esophageal acid may produce bronchoconstriction and, therefore, exacerbate airflow obstruction in asthmatic patients.20–22 However, the impact of GERD therapy on objective outcome measures of asthma control has been variable.23–26 In patients with no evidence of organic disease, the modified F scale was useful to distinguish functional dyspepsia from nonerosive reflux disease, and to assess dyspeptic symptoms.8 Dyspepsia is defined as one or more of the following symptoms: postprandial fullness, early satiation, and epigastric pain or burning.27 Up to 75% of patients have functional dyspepsia with no underlying cause on diagnostic evaluation.28–30 Upper abdominal symptoms, including both GERD and dyspepsia, were well correlated with the degree of asthma symptoms, without enhancing the intensity of eosinophilic inflammation. On the other hand, the coexistence of upper abdominal symptoms, especially dyspepsia, may suggest decreased eosinophilic inflammation. The presence of GERD contributes more to respiratory symptoms associated with asthma than does dyspepsia, although the coexistence of GERD itself never makes eosinophilic inflammation worse.