able 2 Physical activity and physical performance; MHD patients vs. normal controls MHD patients N = 72 Normal controls N = 39 p Value Human activity profile  Maximum activity score 82.5 (13.5) 92 (5) <0.0001  Adjusted activity score 72 (22) 89 (5) <0.0001 Time spent by monitor readings (%)  Sleep or marked physical inactivity 81.9 ± 5.8 72.8 ± 6.0 <0.0001  Light activity 14.4 ± 4.4 20.0 ± 4.5 <0.0001  ≥ Moderate activity 3.7 ± 2.1 7.2 ± 3.0 <0.0001 Average daily physical activity (vector magnitude)  Daily physical activity (mean of 7 days) 395,727 (222,350) 636,112 (243,634) <0.0001  Day of HD 327,250 (188,085)  1-day-post-HD 442,720 (246,824)a  2-days-post HD 393,353 (275,123)b 6-min walk distance (meters) 441.3 ± 121.9 617.6 ± 63.2 <0.0001 Sit-to-stand test (no. cycles in 30 s) 15.9 ± 5.3 26.2 ± 5.4 <0.0001 Stair-climbing test (seconds per 22 stairs) 15.8 ± 11.0 9.8 ± 1.1 <0.0001 Data expressed as mean ± standard deviation. Non-normally distributed data are expressed as median values with the interquartile range (IQR, i.e., the arithmetic difference between the 25th percentile value and the 75th percentile value) shown in parentheses a1-day-post-HD vs day of HD p = 0.018 b2-days-post-HD vs day of HD p = 0.057; 1-day-post-HD vs 2-days-post-HD p = 0.441