Compared with normals, MHD patients had significantly worse scores in all measures of daily physical activity (Table 2). The 7-day mean daily physical activity of MHD patients, measured by the ActiGraph activity monitor and expressed as the VM, averaged 60.8 % of the daily physical activity of normals. MHD patients, in comparison to normals, showed a significantly greater percent of their time in sleep or marked physical inactivity and a significantly smaller percent of their time performing either light daily activity or moderate or greater daily activity. Daily physical activity in the MHD patients varied according to their hemodialysis (HD) schedule (Table 2). Daily physical activity was significantly lower on the day of HD (day 0) than on the day following dialysis (1-day-post-HD). Daily physical activity 2-days-post-HD tended to be greater than daily physical activity on the day of HD and less than daily physical activity on day-1-post-HD but was not statistically different from either of these days. On each of these 3 days of the HD schedule, daily physical activity was significantly lower than the daily physical activity of the normals.