Figure 11 Orthologous neighborhood genes for gene cluster Desgi_1916- 1925, encoding enzymes necessary for butyrate degradation. Purple/pink – acyl-CoA synthetase; red – acyl-CoA dehydrogenase (ACD); orange/dark purple – electron transfer flavoprotein; yellow – Fe-S oxidoreductase; old pink – acetyl-CoA acetyltransferase (ACA); light blue – 3-hydroxybutyryl-CoA dehydrogenase (3-HCD); green – enoyl-CoA hydratase (ECH).