Table 1  Association Results of the HLA Variants for Overall PsV Risk in Multivariate Regression Model
HLA Variant   Frequency   PsV-Affected versus Control Individuals
PsV   Control   OR (95% CI) a   p a
Classical HLA-C Alleles
HLA-C∗06:02  0.23  0.093  3.26 (3.02–3.52)  2.1 × 10−201
HLA-C∗12:03  0.073  0.056  1.38 (1.26–1.52)  6.5 × 10−12
Other four-digit HLA-C alleles  0.70  0.85  reference  reference
HLA-B Amino Acid Position 67
Cys  0.16  0.12  1.56 (1.45–1.67)  6.0 × 10−35
Met  0.12  0.046  1.44 (1.30–1.58)  2.6 × 10−13
Tyr  0.12  0.16  1.00 (0.93–1.07)  0.93
Phe  0.21  0.26  1.00 (0.93–1.08)  0.99
Ser  0.39  0.42  reference  reference
HLA-B Amino Acid Position 9
Asp  0.096  0.11  1.33 (1.21–1.45)  1.6 × 10−9
Tyr  0.70  0.67  reference  reference
His  0.20  0.22  0.87 (0.82–0.92)  1.6 × 10−6
HLA-A Amino Acid Position 95
Val  0.34  0.29  1.31 (1.25–1.38)  4.7 × 10−28
Ile  0.56  0.59  reference  reference
Leu  0.099  0.12  0.89 (0.83–0.95)  7.0 × 10−4
HLA-DQα1 Amino Acid Position 53
Arg  0.37  0.29  1.07 (1.01–1.13)  0.016
Lys  0.39  0.43  reference  reference
Gln  0.25  0.29  0.91 (0.86–0.96)  9.3 × 10−4
Abbreviations are as follows: CI, confidence interval; OR, odds ratio; and PsV, psoriasis vulgaris.
a  Obtained from the multivariate full regression model including the HLA-C, HLA-B, HLA-A, and HLA-DQA1 risk variants identified by the stepwise regression analysis.