Figure 4 Associations of Classical HLA-B Alleles and HLA-B Amino Acid Position 45 for PsA versus PsC Individuals The –log10(p) of HLA-B classical two- and four-digit HLA-B alleles and HLA-B amino acid residues at position 45 in PsA versus PsC individuals. HLA-B Glu45 demonstrated the strongest association (p = 2.9 × 10−12; highlighted with a red circle), whereas the HLA-B classical alleles showed much smaller effects (p > 1.0 × 10−4).