The contribution of HLA-like genes to immune-related disease risk has long been a topic of discussion.38,39 Although our imputation of MICA alleles was highly accurate, our study did not observe independent MICA risk of PsV after we conditioned on the neighboring risk HLA genes HLA-C and HLA-B. Previous studies focusing on MICA risk did not apply robust conditioning on all classical HLA-C and HLA-B alleles and thus could have potentially reflected the associations of HLA-C and HLA-B via LD with them.19,20