(B) Phenotypic analysis of morphant eyes. Injection of 6 ng translation-blocking MO led to a higher number of small eyes than in control-MO-injected larvae. The phenotype could be partially rescued by coinjection of wild-type POC1B mRNA, but not c.199_201del (p.Gln67del) or c.317C>G (p.Arg106Pro) mutant POC1B mRNA.