Postoperative
Examine for signs of bleeding within 24–48 h. Additional doses of DDAVP, EACA, and factor VIII are given as needed. Examine for the signs of allergy to factor VIII. Bleeding can be managed through local means; if these fail, additional systemic therapy may be needed. If infection occurs, treat by local and systemic means. Avoid aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). Acetaminophen with or without codeine may be used.[25]