PMC:400732 / 26486-26977 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T7025","span":{"begin":0,"end":2},"obj":"PRP"},{"id":"T7026","span":{"begin":8,"end":20},"obj":"VBD"},{"id":"T7027","span":{"begin":3,"end":7},"obj":"RB"},{"id":"T7028","span":{"begin":150,"end":158},"obj":"VBD"},{"id":"T7029","span":{"begin":21,"end":24},"obj":"DT"},{"id":"T7030","span":{"begin":25,"end":37},"obj":"NN"},{"id":"T7031","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T7032","span":{"begin":41,"end":49},"obj":"NN"},{"id":"T7033","span":{"begin":50,"end":54},"obj":"NNS"},{"id":"T7034","span":{"begin":55,"end":57},"obj":"IN"},{"id":"T7035","span":{"begin":58,"end":66},"obj":"NN"},{"id":"T7036","span":{"begin":67,"end":75},"obj":"NN"},{"id":"T7037","span":{"begin":76,"end":84},"obj":"NN"},{"id":"T7038","span":{"begin":85,"end":87},"obj":"IN"},{"id":"T7039","span":{"begin":88,"end":97},"obj":"VBG"},{"id":"T7040","span":{"begin":98,"end":101},"obj":"DT"},{"id":"T7041","span":{"begin":116,"end":129},"obj":"NNS"},{"id":"T7042","span":{"begin":102,"end":115},"obj":"NN"},{"id":"T7043","span":{"begin":130,"end":131},"obj":":"},{"id":"T7044","span":{"begin":132,"end":135},"obj":"RB"},{"id":"T7045","span":{"begin":136,"end":139},"obj":"DT"},{"id":"T7046","span":{"begin":147,"end":148},"obj":"NN"},{"id":"T7047","span":{"begin":140,"end":146},"obj":"JJ"},{"id":"T7048","span":{"begin":148,"end":149},"obj":"SYM"},{"id":"T7049","span":{"begin":159,"end":161},"obj":"DT"},{"id":"T7050","span":{"begin":162,"end":172},"obj":"NN"},{"id":"T7051","span":{"begin":173,"end":176},"obj":"CC"},{"id":"T7052","span":{"begin":177,"end":180},"obj":"DT"},{"id":"T7053","span":{"begin":190,"end":191},"obj":"NN"},{"id":"T7054","span":{"begin":181,"end":189},"obj":"JJ"},{"id":"T7055","span":{"begin":197,"end":206},"obj":"VBD"},{"id":"T7056","span":{"begin":191,"end":192},"obj":"SYM"},{"id":"T7057","span":{"begin":193,"end":196},"obj":"RB"},{"id":"T7058","span":{"begin":207,"end":220},"obj":"NN"},{"id":"T7059","span":{"begin":221,"end":233},"obj":"NN"},{"id":"T7060","span":{"begin":233,"end":234},"obj":"."},{"id":"T7061","span":{"begin":234,"end":364},"obj":"sentence"},{"id":"T7062","span":{"begin":235,"end":239},"obj":"DT"},{"id":"T7063","span":{"begin":240,"end":252},"obj":"NN"},{"id":"T7064","span":{"begin":253,"end":260},"obj":"VBZ"},{"id":"T7065","span":{"begin":261,"end":263},"obj":"DT"},{"id":"T7066","span":{"begin":264,"end":274},"obj":"NN"},{"id":"T7067","span":{"begin":275,"end":277},"obj":"IN"},{"id":"T7068","span":{"begin":278,"end":281},"obj":"DT"},{"id":"T7069","span":{"begin":282,"end":289},"obj":"NN"},{"id":"T7070","span":{"begin":290,"end":292},"obj":"TO"},{"id":"T7071","span":{"begin":293,"end":300},"obj":"VB"},{"id":"T7072","span":{"begin":301,"end":310},"obj":"NNS"},{"id":"T7073","span":{"begin":311,"end":313},"obj":"IN"},{"id":"T7074","span":{"begin":314,"end":324},"obj":"RB"},{"id":"T7075","span":{"begin":325,"end":335},"obj":"VBN"},{"id":"T7076","span":{"begin":351,"end":358},"obj":"NNS"},{"id":"T7077","span":{"begin":336,"end":350},"obj":"JJ"},{"id":"T7078","span":{"begin":359,"end":360},"obj":"-LRB-"},{"id":"T7079","span":{"begin":360,"end":362},"obj":"CD"},{"id":"T7080","span":{"begin":362,"end":363},"obj":"-RRB-"},{"id":"T7081","span":{"begin":363,"end":364},"obj":"."},{"id":"T7082","span":{"begin":364,"end":491},"obj":"sentence"},{"id":"T7083","span":{"begin":365,"end":368},"obj":"DT"},{"id":"T7084","span":{"begin":369,"end":375},"obj":"NN"},{"id":"T7085","span":{"begin":440,"end":443},"obj":"VBD"},{"id":"T7086","span":{"begin":376,"end":378},"obj":"IN"},{"id":"T7087","span":{"begin":379,"end":385},"obj":"NNS"},{"id":"T7088","span":{"begin":386,"end":395},"obj":"JJ"},{"id":"T7089","span":{"begin":396,"end":398},"obj":"TO"},{"id":"T7090","span":{"begin":399,"end":408},"obj":"VB"},{"id":"T7091","span":{"begin":409,"end":410},"obj":"CD"},{"id":"T7092","span":{"begin":430,"end":439},"obj":"NNS"},{"id":"T7093","span":{"begin":411,"end":414},"obj":"IN"},{"id":"T7094","span":{"begin":415,"end":417},"obj":"IN"},{"id":"T7095","span":{"begin":418,"end":420},"obj":"CD"},{"id":"T7096","span":{"begin":421,"end":429},"obj":"JJ"},{"id":"T7097","span":{"begin":444,"end":447},"obj":"PRP$"},{"id":"T7098","span":{"begin":448,"end":458},"obj":"NN"},{"id":"T7099","span":{"begin":459,"end":461},"obj":"IN"},{"id":"T7100","span":{"begin":462,"end":472},"obj":"JJ"},{"id":"T7101","span":{"begin":482,"end":490},"obj":"NN"},{"id":"T7102","span":{"begin":473,"end":481},"obj":"NN"},{"id":"T7103","span":{"begin":490,"end":491},"obj":"."}],"relations":[{"id":"R4720","pred":"nsubj","subj":"T7025","obj":"T7026"},{"id":"R4721","pred":"ccomp","subj":"T7026","obj":"T7028"},{"id":"R4722","pred":"advmod","subj":"T7027","obj":"T7026"},{"id":"R4723","pred":"det","subj":"T7029","obj":"T7030"},{"id":"R4724","pred":"dobj","subj":"T7030","obj":"T7026"},{"id":"R4725","pred":"prep","subj":"T7031","obj":"T7030"},{"id":"R4726","pred":"compound","subj":"T7032","obj":"T7033"},{"id":"R4727","pred":"pobj","subj":"T7033","obj":"T7031"},{"id":"R4728","pred":"prep","subj":"T7034","obj":"T7030"},{"id":"R4729","pred":"compound","subj":"T7035","obj":"T7036"},{"id":"R4730","pred":"compound","subj":"T7036","obj":"T7037"},{"id":"R4731","pred":"pobj","subj":"T7037","obj":"T7034"},{"id":"R4732","pred":"prep","subj":"T7038","obj":"T7026"},{"id":"R4733","pred":"pcomp","subj":"T7039","obj":"T7038"},{"id":"R4734","pred":"det","subj":"T7040","obj":"T7041"},{"id":"R4735","pred":"dobj","subj":"T7041","obj":"T7039"},{"id":"R4736","pred":"compound","subj":"T7042","obj":"T7041"},{"id":"R4737","pred":"punct","subj":"T7043","obj":"T7028"},{"id":"R4738","pred":"advmod","subj":"T7044","obj":"T7028"},{"id":"R4739","pred":"det","subj":"T7045","obj":"T7046"},{"id":"R4740","pred":"nsubj","subj":"T7046","obj":"T7028"},{"id":"R4741","pred":"amod","subj":"T7047","obj":"T7046"},{"id":"R4742","pred":"punct","subj":"T7048","obj":"T7046"},{"id":"R4743","pred":"det","subj":"T7049","obj":"T7050"},{"id":"R4744","pred":"dobj","subj":"T7050","obj":"T7028"},{"id":"R4745","pred":"cc","subj":"T7051","obj":"T7028"},{"id":"R4746","pred":"det","subj":"T7052","obj":"T7053"},{"id":"R4747","pred":"nsubj","subj":"T7053","obj":"T7055"},{"id":"R4748","pred":"amod","subj":"T7054","obj":"T7053"},{"id":"R4749","pred":"conj","subj":"T7055","obj":"T7028"},{"id":"R4750","pred":"punct","subj":"T7056","obj":"T7053"},{"id":"R4751","pred":"advmod","subj":"T7057","obj":"T7055"},{"id":"R4752","pred":"compound","subj":"T7058","obj":"T7059"},{"id":"R4753","pred":"dobj","subj":"T7059","obj":"T7055"},{"id":"R4754","pred":"punct","subj":"T7060","obj":"T7028"},{"id":"R4755","pred":"det","subj":"T7062","obj":"T7063"},{"id":"R4756","pred":"nsubj","subj":"T7063","obj":"T7064"},{"id":"R4757","pred":"det","subj":"T7065","obj":"T7066"},{"id":"R4758","pred":"dobj","subj":"T7066","obj":"T7064"},{"id":"R4759","pred":"prep","subj":"T7067","obj":"T7066"},{"id":"R4760","pred":"det","subj":"T7068","obj":"T7069"},{"id":"R4761","pred":"pobj","subj":"T7069","obj":"T7067"},{"id":"R4762","pred":"aux","subj":"T7070","obj":"T7071"},{"id":"R4763","pred":"acl","subj":"T7071","obj":"T7069"},{"id":"R4764","pred":"dobj","subj":"T7072","obj":"T7071"},{"id":"R4765","pred":"prep","subj":"T7073","obj":"T7072"},{"id":"R4766","pred":"advmod","subj":"T7074","obj":"T7075"},{"id":"R4767","pred":"amod","subj":"T7075","obj":"T7076"},{"id":"R4768","pred":"pobj","subj":"T7076","obj":"T7073"},{"id":"R4769","pred":"amod","subj":"T7077","obj":"T7076"},{"id":"R4770","pred":"punct","subj":"T7078","obj":"T7079"},{"id":"R4771","pred":"parataxis","subj":"T7079","obj":"T7071"},{"id":"R4772","pred":"punct","subj":"T7080","obj":"T7079"},{"id":"R4773","pred":"punct","subj":"T7081","obj":"T7064"},{"id":"R4774","pred":"det","subj":"T7083","obj":"T7084"},{"id":"R4775","pred":"nsubj","subj":"T7084","obj":"T7085"},{"id":"R4776","pred":"prep","subj":"T7086","obj":"T7084"},{"id":"R4777","pred":"pobj","subj":"T7087","obj":"T7086"},{"id":"R4778","pred":"amod","subj":"T7088","obj":"T7084"},{"id":"R4779","pred":"aux","subj":"T7089","obj":"T7090"},{"id":"R4780","pred":"xcomp","subj":"T7090","obj":"T7088"},{"id":"R4781","pred":"nummod","subj":"T7091","obj":"T7092"},{"id":"R4782","pred":"dobj","subj":"T7092","obj":"T7090"},{"id":"R4783","pred":"prep","subj":"T7093","obj":"T7091"},{"id":"R4784","pred":"prep","subj":"T7094","obj":"T7093"},{"id":"R4785","pred":"pobj","subj":"T7095","obj":"T7094"},{"id":"R4786","pred":"amod","subj":"T7096","obj":"T7092"},{"id":"R4787","pred":"poss","subj":"T7097","obj":"T7098"},{"id":"R4788","pred":"attr","subj":"T7098","obj":"T7085"},{"id":"R4789","pred":"prep","subj":"T7099","obj":"T7098"},{"id":"R4790","pred":"amod","subj":"T7100","obj":"T7101"},{"id":"R4791","pred":"pobj","subj":"T7101","obj":"T7099"},{"id":"R4792","pred":"compound","subj":"T7102","obj":"T7101"},{"id":"R4793","pred":"punct","subj":"T7103","obj":"T7085"}],"text":"We next investigated the contribution of dopamine D2Rs to reversal learning behavior by inverting the reinforcement contingencies – now the former S+ signaled no reinforcer and the previous S- now indicated reinforcement availability. This manipulation permits an evaluation of the ability to inhibit responses to previously reinforced discriminative stimuli [18]. The number of trials necessary to establish 8 out of 10 accurate responses was our definition of successful reversal learning."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6397","span":{"begin":41,"end":49},"obj":"CHEBI:18243"},{"id":"T6398","span":{"begin":41,"end":54},"obj":"PR_EXT:000001177"},{"id":"T6399","span":{"begin":67,"end":75},"obj":"GO:0007612"},{"id":"T6400","span":{"begin":76,"end":84},"obj":"GO_PATO_EXT:biological_behavior"},{"id":"T6401","span":{"begin":301,"end":310},"obj":"GO_EXT:reaction_or_response"},{"id":"T6402","span":{"begin":430,"end":439},"obj":"GO_EXT:reaction_or_response"},{"id":"T6403","span":{"begin":482,"end":490},"obj":"GO:0007612"}],"text":"We next investigated the contribution of dopamine D2Rs to reversal learning behavior by inverting the reinforcement contingencies – now the former S+ signaled no reinforcer and the previous S- now indicated reinforcement availability. This manipulation permits an evaluation of the ability to inhibit responses to previously reinforced discriminative stimuli [18]. The number of trials necessary to establish 8 out of 10 accurate responses was our definition of successful reversal learning."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T6345","span":{"begin":41,"end":49},"obj":"CHEBI:18243"},{"id":"T6346","span":{"begin":41,"end":54},"obj":"PR:000001177"},{"id":"T6347","span":{"begin":67,"end":75},"obj":"GO:0007612"},{"id":"T6348","span":{"begin":482,"end":490},"obj":"GO:0007612"}],"text":"We next investigated the contribution of dopamine D2Rs to reversal learning behavior by inverting the reinforcement contingencies – now the former S+ signaled no reinforcer and the previous S- now indicated reinforcement availability. This manipulation permits an evaluation of the ability to inhibit responses to previously reinforced discriminative stimuli [18]. The number of trials necessary to establish 8 out of 10 accurate responses was our definition of successful reversal learning."}

{"project":"2_test","denotations":[{"id":"15061865-11323267-12857769","span":{"begin":360,"end":362},"obj":"11323267"}],"text":"We next investigated the contribution of dopamine D2Rs to reversal learning behavior by inverting the reinforcement contingencies – now the former S+ signaled no reinforcer and the previous S- now indicated reinforcement availability. This manipulation permits an evaluation of the ability to inhibit responses to previously reinforced discriminative stimuli [18]. The number of trials necessary to establish 8 out of 10 accurate responses was our definition of successful reversal learning."}