Statistical analysis
The statistical analysis was performed to represent the data in mean±S.E. values. Results were based on at least three separate experiments unless specified with each experiment performed in triplicates. For the comparison between mock/control group, treatments were performed using two-tailed Student's t-test to calculate P-values, and P-value ≤0.05 was considered statistically significant. The P-value ≤0.05 was indicated by ‘*' and ≤0.01 was indicated by ‘**' in the bar graphs. Experiments involving two variables were analyzed using two-way ANOVA to address whether they interact with each other in a synergistic manner. To examine dose-dependent effect of the inhibitors, results were analyzed using P-value for trend test using general linear model. No adjustments were made in the statistical analysis for multiple comparisons.