Experiment 3: Effect of SB242084 on Unrewarded Choice Behaviour Animals spent more time in the novel arm and made more arm-entries into the novel arm, and SB242084 had no effect on either of these measures (Table 4). There were no effects of maze-configuration or drug × maze-configuration interaction on entries into the novel or old arms. There were significant effects of phase (pre- and post-change) on proportion of time (F1,26 = 12.27, p<.01) and proportion of arm-entries made into the novel arm (F1,26 = 34.78, p<.0001). There were no effects of drug (p ≥.16) or drug × phase interactions (p ≥.19) on proportion of time spent in the novel arm or proportion of arm entries made into the novel arm. 10.1371/journal.pone.0077762.t004 Table 4 Proportion of time and proportion of entries (± SEM) before a 45° shift (pre-shift) and after a 45° shift (post-shift) in vehicle and SB242084 treated animals. ** p<.01. D