10.1371/journal.pone.0064525.g001 Figure 1  SCD1 expression and activity in ALS mouse muscle.
(A) Time course of SCD1 expression in gastrocnemius (GT, brown columns) and tibialis anterior (TA, orange columns) from SOD1(G86R) mice at indicated ages. Wild-type expression is represented by 100% baseline. ***P<0.001 (One sample t-test, n = 5–11). (B) C18:1/C18:0 fatty acid ratio in gastrocnemius and tibialis anterior from SOD1(G86R) mice (brown columns) and wild-type littermates (white columns) at indicated ages. *P<0.05 (1-way ANOVA followed by Bonferroni's multiple comparison test for gastrocnemius, and unpaired t-test for tibialis anterior, n = 3–10).