NAcb-DBS did not Influence Locomotor Activity of HAB Mice To exclude the possibility that the observed behavioral changes following repeated NAcb-DBS were affected by unspecific alterations in general locomotion, locomotor activity of animals was studied in an open field (see scheme in Figure 2a). Following five DBS stimulations, the distance traveled in the open field by HAB mice did not differ within the first 5 min (t=1.410, P=0.178), reflecting the testing period of the TST and FST, or during the total 10 min testing time (t=0.007, P=0.994; Table 1).