10.1371/journal.pone.0061634.g008 Figure 8  Schematic representation of the cAMP-dependent pathway leading to ABCB transcriptional regulation in mussel haemocytes.
5-HT1: type 1 serotonin receptor; 5-HT: serotonin; PROP: propranolol; Gi: inhibitory G-protein; AC: adenylyl cyclase; FSK: forskolin; cAMP: cyclic-AMP; PKA(i): inactivated cAMP-dependent protein kinase (PKA); PKA(a): activated PKA (catalytic subunit); dbcAMP: dybutyril cAMP; H89: N-[2-((p-Bromocinnamyl)amino)ethyl]-5-isoquinolinesulfonamide dihydrochloride; CRF: cAMP-responsive factors.