PMC:3589482 / 1335-1679 JSONTXT

Annnotations TAB JSON ListView MergeView

    bionlp-st-ge-2016-spacy-parsed

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(EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    pmc-enju-pas

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(EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T169","span":{"begin":105,"end":112},"obj":"Protein"},{"id":"T170","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T171","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T172","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T173","span":{"begin":315,"end":322},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T525","span":{"begin":105,"end":112},"obj":"http://www.uniprot.org/uniprot/P28033"},{"id":"T526","span":{"begin":255,"end":262},"obj":"http://www.uniprot.org/uniprot/P28033"},{"id":"T527","span":{"begin":315,"end":322},"obj":"http://www.uniprot.org/uniprot/P28033"},{"id":"T535","span":{"begin":143,"end":151},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T536","span":{"begin":209,"end":217},"obj":"http://www.uniprot.org/uniprot/P05120"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T186","span":{"begin":92,"end":101},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T190","span":{"begin":14,"end":23},"obj":"http://purl.obolibrary.org/obo/GO_0000785"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    simple1

    {"project":"simple1","denotations":[{"id":"T226","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T222","span":{"begin":105,"end":112},"obj":"Protein"},{"id":"T223","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T224","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T225","span":{"begin":255,"end":262},"obj":"Protein"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T520","span":{"begin":242,"end":251},"obj":"Negative_regulation"},{"id":"T519","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T518","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T517","span":{"begin":197,"end":208},"obj":"Positive_regulation"},{"id":"T516","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T515","span":{"begin":92,"end":101},"obj":"Binding"},{"id":"T507","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T506","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T505","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T504","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T503","span":{"begin":105,"end":112},"obj":"Protein"}],"relations":[{"id":"R302","pred":"themeOf","subj":"T503","obj":"T515"},{"id":"R303","pred":"themeOf","subj":"T504","obj":"T515"},{"id":"R304","pred":"themeOf","subj":"T505","obj":"T519"},{"id":"R305","pred":"themeOf","subj":"T507","obj":"T518"},{"id":"R309","pred":"themeOf","subj":"T515","obj":"T516"},{"id":"R310","pred":"themeOf","subj":"T515","obj":"T516"},{"id":"R311","pred":"themeOf","subj":"T519","obj":"T520"},{"id":"R312","pred":"themeOf","subj":"T519","obj":"T517"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T630","span":{"begin":197,"end":208},"obj":"Positive_regulation"},{"id":"T631","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T613","span":{"begin":105,"end":112},"obj":"Protein"},{"id":"T614","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T615","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T616","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T617","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T625","span":{"begin":92,"end":101},"obj":"Localization"},{"id":"T626","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T627","span":{"begin":263,"end":267},"obj":"Negative_regulation"},{"id":"T628","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T629","span":{"begin":242,"end":251},"obj":"Negative_regulation"}],"relations":[{"id":"R722","pred":"themeOf","subj":"T613","obj":"T625"},{"id":"R725","pred":"themeOf","subj":"T614","obj":"T626"},{"id":"R726","pred":"themeOf","subj":"T614","obj":"T625"},{"id":"R734","pred":"themeOf","subj":"T625","obj":"T626"},{"id":"R735","pred":"themeOf","subj":"T625","obj":"T626"},{"id":"R737","pred":"themeOf","subj":"T631","obj":"T629"},{"id":"R727","pred":"themeOf","subj":"T615","obj":"T631"},{"id":"R729","pred":"themeOf","subj":"T616","obj":"T627"},{"id":"R730","pred":"themeOf","subj":"T617","obj":"T628"},{"id":"R736","pred":"causeOf","subj":"T628","obj":"T629"},{"id":"R740","pred":"themeOf","subj":"T631","obj":"T630"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T596","span":{"begin":197,"end":208},"obj":"Positive_regulation"},{"id":"T595","span":{"begin":180,"end":192},"obj":"Positive_regulation"},{"id":"T594","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T593","span":{"begin":242,"end":251},"obj":"Negative_regulation"},{"id":"T592","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T579","span":{"begin":105,"end":112},"obj":"Protein"},{"id":"T580","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T581","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T582","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T583","span":{"begin":315,"end":322},"obj":"Protein"}],"relations":[{"id":"R318","pred":"themeOf","subj":"T592","obj":"T596"},{"id":"R316","pred":"themeOf","subj":"T592","obj":"T593"},{"id":"R687","pred":"themeOf","subj":"T581","obj":"T592"},{"id":"R688","pred":"themeOf","subj":"T583","obj":"T594"},{"id":"R317","pred":"themeOf","subj":"T592","obj":"T595"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T757","span":{"begin":88,"end":160},"obj":"Gene_expression"},{"id":"T754","span":{"begin":139,"end":160},"obj":"Entity"},{"id":"T708","span":{"begin":274,"end":302},"obj":"Entity"},{"id":"T710","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T712","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T717","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T718","span":{"begin":102,"end":160},"obj":"Protein"},{"id":"T721","span":{"begin":297,"end":301},"obj":"Protein"},{"id":"T735","span":{"begin":76,"end":79},"obj":"Entity"},{"id":"T736","span":{"begin":197,"end":208},"obj":"Entity"},{"id":"T737","span":{"begin":124,"end":160},"obj":"Entity"},{"id":"T746","span":{"begin":14,"end":23},"obj":"Entity"}],"relations":[{"id":"R719","pred":"themeOf","subj":"T718","obj":"T757"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T665","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T664","span":{"begin":242,"end":251},"obj":"Negative_regulation"},{"id":"T663","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T662","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T661","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T660","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T659","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T658","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T657","span":{"begin":124,"end":133},"obj":"Binding"},{"id":"T656","span":{"begin":124,"end":133},"obj":"Binding"},{"id":"T655","span":{"begin":143,"end":160},"obj":"Protein"},{"id":"T654","span":{"begin":105,"end":112},"obj":"Protein"}],"relations":[{"id":"R326","pred":"themeOf","subj":"T654","obj":"T656"},{"id":"R327","pred":"themeOf","subj":"T654","obj":"T657"},{"id":"R328","pred":"themeOf","subj":"T655","obj":"T657"},{"id":"R329","pred":"themeOf","subj":"T656","obj":"T658"},{"id":"R330","pred":"themeOf","subj":"T657","obj":"T659"},{"id":"R331","pred":"themeOf","subj":"T660","obj":"T663"},{"id":"R332","pred":"themeOf","subj":"T662","obj":"T665"},{"id":"R333","pred":"themeOf","subj":"T663","obj":"T664"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    testone

    {"project":"testone","denotations":[{"id":"T46","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T45","span":{"begin":263,"end":267},"obj":"Negative_regulation"},{"id":"T44","span":{"begin":242,"end":251},"obj":"Negative_regulation"},{"id":"T43","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T42","span":{"begin":201,"end":208},"obj":"Positive_regulation"},{"id":"T41","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T36","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T35","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T34","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T33","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T32","span":{"begin":105,"end":112},"obj":"Protein"}],"relations":[{"id":"R4","pred":"themeOf","subj":"T34","obj":"T43"},{"id":"R6","pred":"themeOf","subj":"T36","obj":"T46"},{"id":"R9","pred":"themeOf","subj":"T42","obj":"T44"},{"id":"R10","pred":"themeOf","subj":"T43","obj":"T42"},{"id":"R11","pred":"themeOf","subj":"T43","obj":"T44"},{"id":"R12","pred":"causeOf","subj":"T45","obj":"T44"},{"id":"R13","pred":"causeOf","subj":"T46","obj":"T44"},{"id":"R5","pred":"themeOf","subj":"T35","obj":"T45"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}

    test3

    {"project":"test3","denotations":[{"id":"T93","span":{"begin":323,"end":332},"obj":"Negative_regulation"},{"id":"T92","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T91","span":{"begin":263,"end":267},"obj":"Negative_regulation"},{"id":"T90","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T89","span":{"begin":242,"end":251},"obj":"Negative_regulation"},{"id":"T88","span":{"begin":218,"end":228},"obj":"Gene_expression"},{"id":"T87","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T86","span":{"begin":201,"end":208},"obj":"Positive_regulation"},{"id":"T85","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T84","span":{"begin":105,"end":112},"obj":"Protein"},{"id":"T83","span":{"begin":80,"end":87},"obj":"Positive_regulation"},{"id":"T65","span":{"begin":315,"end":322},"obj":"Protein"},{"id":"T64","span":{"begin":255,"end":262},"obj":"Protein"},{"id":"T63","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T62","span":{"begin":143,"end":151},"obj":"Protein"},{"id":"T61","span":{"begin":105,"end":112},"obj":"Protein"}],"relations":[{"id":"R21","pred":"themeOf","subj":"T87","obj":"T88"},{"id":"R22","pred":"themeOf","subj":"T88","obj":"T86"},{"id":"R23","pred":"themeOf","subj":"T88","obj":"T89"},{"id":"R24","pred":"themeOf","subj":"T90","obj":"T91"},{"id":"R25","pred":"causeOf","subj":"T91","obj":"T89"},{"id":"R26","pred":"themeOf","subj":"T92","obj":"T93"},{"id":"R20","pred":"themeOf","subj":"T86","obj":"T89"},{"id":"R27","pred":"causeOf","subj":"T93","obj":"T89"}],"text":"ft (EMSA) and chromatin immunoprecipitation (ChIP) assays demonstrated that LPS induces the formation of C/EBP-β containing complexes with the SerpinB2 promoter. Importantly, both constitutive and LPS-induced SerpinB2 expression was severely abrogated in C/EBP-β-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-β-deficient peritoneal "}