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PMC:3585731 / 21889-22645 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T8937 560-569 Negative_regulation denotes Knockdown
T8936 527-536 Negative_regulation denotes inhibited
T8935 488-497 Negative_regulation denotes inhibitor
T8934 320-329 Negative_regulation denotes inhibitor
T8933 282-292 Negative_regulation denotes inhibition
T8899 727-731 Protein denotes TNFα
T8898 352-358 Protein denotes Raptor
R5803 T8898 T8934 themeOf Raptor,inhibitor

2_test

Id Subject Object Predicate Lexical cue
23469174-18955974-90505435 156-158 18955974 denotes 28
23469174-12150925-90505436 360-362 12150925 denotes 29
23469174-20860370-90505437 461-463 20860370 denotes 30
23469174-16697955-90505438 506-508 16697955 denotes 31

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T9757 754-755 -RRB- denotes )
T9756 752-754 NN denotes 5D
T9755 747-751 NN denotes Fig.
T9754 746-747 -LRB- denotes (
T9753 740-745 NN denotes death
T9752 732-739 VB denotes induced
T9751 727-731 NN denotes TNFα
T9750 723-726 CC denotes and
T9749 714-722 NN denotes zVAD.fmk
T9748 709-713 CC denotes both
T9747 704-708 IN denotes from
T9746 698-703 NN denotes cells
T9745 687-697 VB denotes protecting
T9744 684-686 IN denotes by
T9743 672-683 NN denotes necroptosis
T9742 669-671 IN denotes in
T9741 664-668 NN denotes mTOR
T9740 660-663 IN denotes for
T9739 655-659 NN denotes role
T9738 653-654 DT denotes a
T9737 642-652 VB denotes indicating
T9736 637-641 NN denotes data
T9735 627-636 NN denotes inhibitor
T9734 612-626 JJ denotes small-molecule
T9733 608-611 DT denotes the
T9732 598-607 VB denotes validated
T9731 590-597 RB denotes further
T9730 584-589 NN denotes siRNA
T9729 578-583 VB denotes using
T9728 573-577 NN denotes mTOR
T9727 570-572 IN denotes of
T9726 560-569 NN denotes Knockdown
T9725 557-558 -RRB- denotes )
T9724 555-557 NN denotes 5C
T9723 550-554 NN denotes Fig.
T9722 549-550 -LRB- denotes (
T9721 537-548 NN denotes necroptosis
T9720 527-536 VB denotes inhibited
T9719 515-526 RB denotes efficiently
T9718 510-514 RB denotes also
T9717 508-509 -RRB- denotes ]
T9716 506-508 CD denotes 31
T9715 505-506 -LRB- denotes [
T9714 498-504 NN denotes PI-103
T9713 488-497 NN denotes inhibitor
T9712 478-487 NN denotes PI3K/mTOR
T9711 473-477 JJ denotes dual
T9710 469-472 DT denotes the
T9709 465-468 CC denotes and
T9708 463-464 -RRB- denotes ]
T9707 461-463 CD denotes 30
T9706 460-461 -LRB- denotes [
T9705 453-459 NN denotes Torin1
T9704 443-452 NN denotes inhibitor
T9703 436-442 NN denotes kinase
T9702 431-435 NN denotes mTOR
T9701 424-430 JJ denotes direct
T9700 420-423 DT denotes the
T9699 418-419 -COMMA- denotes ,
T9698 409-418 RB denotes Similarly
T9697 406-407 -RRB- denotes )
T9696 404-406 NN denotes 5C
T9695 399-403 NN denotes Fig.
T9694 398-399 -LRB- denotes (
T9693 386-397 NN denotes necroptosis
T9692 381-385 IN denotes from
T9691 375-380 NN denotes cells
T9690 365-374 JJ denotes protected
T9689 363-364 -COMMA- denotes ,
T9688 362-363 -RRB- denotes ]
T9687 360-362 CD denotes 29
T9686 359-360 -LRB- denotes [
T9685 352-358 NN denotes Raptor
T9684 342-351 NN denotes co-factor
T9683 337-341 NN denotes mTOR
T9682 333-336 DT denotes the
T9681 330-332 IN denotes of
T9680 320-329 NN denotes inhibitor
T9679 317-319 DT denotes an
T9678 315-316 -COMMA- denotes ,
T9677 306-315 NN denotes rapamycin
T9676 303-305 IN denotes by
T9675 296-302 NN denotes mTORC1
T9674 293-295 IN denotes of
T9673 282-292 NN denotes inhibition
T9672 277-281 IN denotes that
T9671 271-276 VB denotes found
T9670 268-270 PRP denotes We
T9669 255-266 NN denotes necroptosis
T9668 248-254 IN denotes during
T9667 242-247 NN denotes roles
T9666 229-241 JJ denotes pro-survival
T9665 223-228 PRP-DOLLAR- denotes their
T9664 215-222 VB denotes reverse
T9663 205-214 NN denotes molecules
T9662 200-204 JJ denotes same
T9661 194-199 DT denotes these
T9660 186-193 IN denotes whether
T9659 183-185 VB denotes is
T9658 174-182 NN denotes question
T9657 164-173 JJ denotes important
T9656 161-163 DT denotes An
T9655 158-159 -RRB- denotes ]
T9654 156-158 CD denotes 28
T9653 155-156 -LRB- denotes [
T9652 148-154 NN denotes others
T9651 144-147 CC denotes and
T9650 138-143 NN denotes GSK-3
T9649 136-137 -COMMA- denotes ,
T9648 130-136 NN denotes mTORC1
T9647 120-129 VB denotes including
T9646 110-119 NN denotes effectors
T9645 101-109 JJ denotes multiple
T9644 98-100 IN denotes of
T9643 90-97 NN denotes control
T9642 86-89 DT denotes the
T9641 78-85 IN denotes through
T9640 68-77 NN denotes apoptosis
T9639 59-67 VB denotes inhibits
T9638 54-58 WDT denotes that
T9637 46-53 NN denotes protein
T9636 33-45 JJ denotes pro-survival
T9635 31-32 DT denotes a
T9634 28-30 VB denotes be
T9633 25-27 TO denotes to
T9632 14-24 VB denotes considered
T9631 11-13 VB denotes is
T9630 4-10 NN denotes kinase
T9629 0-3 NN denotes Akt
R6144 T9630 T9629 arg1Of kinase,Akt
R6145 T9630 T9631 arg1Of kinase,is
R6146 T9630 T9632 arg2Of kinase,considered
R6147 T9630 T9634 arg1Of kinase,be
R6148 T9632 T9631 arg2Of considered,is
R6149 T9634 T9632 arg3Of be,considered
R6150 T9634 T9633 arg1Of be,to
R6151 T9637 T9634 arg2Of protein,be
R6152 T9637 T9635 arg1Of protein,a
R6153 T9637 T9636 arg1Of protein,pro-survival
R6154 T9637 T9638 arg1Of protein,that
R6155 T9637 T9639 arg1Of protein,inhibits
R6156 T9639 T9641 arg1Of inhibits,through
R6157 T9640 T9639 arg2Of apoptosis,inhibits
R6158 T9643 T9641 arg2Of control,through
R6159 T9643 T9642 arg1Of control,the
R6160 T9643 T9644 arg1Of control,of
R6161 T9646 T9644 arg2Of effectors,of
R6162 T9646 T9645 arg1Of effectors,multiple
R6163 T9646 T9647 arg1Of effectors,including
R6164 T9648 T9649 arg1Of mTORC1,","
R6165 T9649 T9651 arg1Of ",",and
R6166 T9650 T9649 arg2Of GSK-3,","
R6167 T9651 T9647 arg2Of and,including
R6168 T9651 T9653 arg1Of and,[
R6169 T9652 T9651 arg2Of others,and
R6170 T9654 T9653 arg2Of 28,[
R6171 T9655 T9653 arg3Of ],[
R6172 T9658 T9656 arg1Of question,An
R6173 T9658 T9657 arg1Of question,important
R6174 T9658 T9659 arg1Of question,is
R6175 T9663 T9661 arg1Of molecules,these
R6176 T9663 T9662 arg1Of molecules,same
R6177 T9663 T9664 arg1Of molecules,reverse
R6178 T9664 T9659 arg2Of reverse,is
R6179 T9664 T9660 arg1Of reverse,whether
R6180 T9664 T9668 arg1Of reverse,during
R6181 T9667 T9664 arg2Of roles,reverse
R6182 T9667 T9665 arg1Of roles,their
R6183 T9667 T9666 arg1Of roles,pro-survival
R6184 T9669 T9668 arg2Of necroptosis,during
R6185 T9670 T9671 arg1Of We,found
R6186 T9673 T9674 arg1Of inhibition,of
R6187 T9673 T9676 arg1Of inhibition,by
R6188 T9673 T9689 arg1Of inhibition,","
R6189 T9673 T9690 arg1Of inhibition,protected
R6190 T9675 T9674 arg2Of mTORC1,of
R6191 T9677 T9676 arg2Of rapamycin,by
R6192 T9677 T9678 arg1Of rapamycin,","
R6193 T9680 T9678 arg2Of inhibitor,","
R6194 T9680 T9679 arg1Of inhibitor,an
R6195 T9680 T9681 arg1Of inhibitor,of
R6196 T9685 T9681 arg2Of Raptor,of
R6197 T9685 T9682 arg1Of Raptor,the
R6198 T9685 T9683 arg1Of Raptor,mTOR
R6199 T9685 T9684 arg1Of Raptor,co-factor
R6200 T9685 T9686 arg1Of Raptor,[
R6201 T9687 T9686 arg2Of 29,[
R6202 T9688 T9686 arg3Of ],[
R6203 T9690 T9671 arg2Of protected,found
R6204 T9690 T9672 arg1Of protected,that
R6205 T9691 T9690 arg2Of cells,protected
R6206 T9691 T9692 arg1Of cells,from
R6207 T9691 T9694 arg1Of cells,(
R6208 T9693 T9692 arg2Of necroptosis,from
R6209 T9696 T9694 arg2Of 5C,(
R6210 T9696 T9695 arg1Of 5C,Fig.
R6211 T9697 T9694 arg3Of ),(
R6212 T9705 T9700 arg1Of Torin1,the
R6213 T9705 T9701 arg1Of Torin1,direct
R6214 T9705 T9702 arg1Of Torin1,mTOR
R6215 T9705 T9703 arg1Of Torin1,kinase
R6216 T9705 T9704 arg1Of Torin1,inhibitor
R6217 T9705 T9706 arg1Of Torin1,[
R6218 T9705 T9709 arg1Of Torin1,and
R6219 T9707 T9706 arg2Of 30,[
R6220 T9708 T9706 arg3Of ],[
R6221 T9709 T9720 arg1Of and,inhibited
R6222 T9714 T9709 arg2Of PI-103,and
R6223 T9714 T9710 arg1Of PI-103,the
R6224 T9714 T9711 arg1Of PI-103,dual
R6225 T9714 T9712 arg1Of PI-103,PI3K/mTOR
R6226 T9714 T9713 arg1Of PI-103,inhibitor
R6227 T9714 T9715 arg1Of PI-103,[
R6228 T9716 T9715 arg2Of 31,[
R6229 T9717 T9715 arg3Of ],[
R6230 T9720 T9698 arg1Of inhibited,Similarly
R6231 T9720 T9699 arg1Of inhibited,","
R6232 T9720 T9718 arg1Of inhibited,also
R6233 T9720 T9719 arg1Of inhibited,efficiently
R6234 T9721 T9720 arg2Of necroptosis,inhibited
R6235 T9721 T9722 arg1Of necroptosis,(
R6236 T9724 T9722 arg2Of 5C,(
R6237 T9724 T9723 arg1Of 5C,Fig.
R6238 T9725 T9722 arg3Of ),(
R6239 T9726 T9727 arg1Of Knockdown,of
R6240 T9726 T9729 arg1Of Knockdown,using
R6241 T9726 T9732 arg1Of Knockdown,validated
R6242 T9728 T9727 arg2Of mTOR,of
R6243 T9730 T9729 arg2Of siRNA,using
R6244 T9732 T9731 arg1Of validated,further
R6245 T9736 T9732 arg2Of data,validated
R6246 T9736 T9733 arg1Of data,the
R6247 T9736 T9734 arg1Of data,small-molecule
R6248 T9736 T9735 arg1Of data,inhibitor
R6249 T9736 T9737 arg1Of data,indicating
R6250 T9736 T9745 arg1Of data,protecting
R6251 T9736 T9752 arg1Of data,induced
R6252 T9737 T9744 arg1Of indicating,by
R6253 T9739 T9737 arg2Of role,indicating
R6254 T9739 T9738 arg1Of role,a
R6255 T9739 T9740 arg1Of role,for
R6256 T9739 T9742 arg1Of role,in
R6257 T9741 T9740 arg2Of mTOR,for
R6258 T9743 T9742 arg2Of necroptosis,in
R6259 T9745 T9744 arg2Of protecting,by
R6260 T9746 T9745 arg2Of cells,protecting
R6261 T9746 T9747 arg1Of cells,from
R6262 T9749 T9750 arg1Of zVAD.fmk,and
R6263 T9750 T9747 arg2Of and,from
R6264 T9750 T9748 arg1Of and,both
R6265 T9751 T9750 arg2Of TNFα,and
R6266 T9752 T9732 arg3Of induced,validated
R6267 T9753 T9752 arg2Of death,induced
R6268 T9753 T9754 arg1Of death,(
R6269 T9756 T9754 arg2Of 5D,(
R6270 T9756 T9755 arg1Of 5D,Fig.
R6271 T9757 T9754 arg3Of ),(

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T9214 727-731 Protein denotes TNFα
T9213 352-358 Protein denotes Raptor

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T10267 0-3 http://www.uniprot.org/uniprot/P31751 denotes Akt
T10253 0-3 http://www.uniprot.org/uniprot/P31749 denotes Akt
T10298 664-668 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T10297 573-577 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T10296 483-487 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T10295 431-435 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T10294 337-341 http://www.uniprot.org/uniprot/P42345 denotes mTOR
T10281 0-3 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T10300 727-731 http://www.uniprot.org/uniprot/P01375 denotes TNFα

GO-BP

Id Subject Object Predicate Lexical cue
T9305 478-482 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T9304 436-452 http://purl.obolibrary.org/obo/GO_0033673 denotes kinase inhibitor
T9303 68-77 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T9302 68-77 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T9301 229-241 http://purl.obolibrary.org/obo/GO_0043066 denotes pro-survival
T9300 33-45 http://purl.obolibrary.org/obo/GO_0043066 denotes pro-survival
T9298 740-745 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T9292 138-141 http://purl.obolibrary.org/obo/GO_0050321 denotes GSK
T9270 672-683 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T9269 537-548 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T9268 386-397 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T9267 255-266 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T9249 672-683 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T9248 537-548 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T9247 386-397 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T9246 255-266 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T9319 478-482 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T9316 138-141 http://purl.obolibrary.org/obo/GO_0050321 denotes GSK

GO-CC

Id Subject Object Predicate Lexical cue
T9329 296-302 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1
T9328 130-136 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1

sentences

Id Subject Object Predicate Lexical cue
T9098 560-756 Sentence denotes Knockdown of mTOR using siRNA further validated the small-molecule inhibitor data indicating a role for mTOR in necroptosis by protecting cells from both zVAD.fmk and TNFα induced death (Fig. 5D).
T9097 409-559 Sentence denotes Similarly, the direct mTOR kinase inhibitor Torin1 [30] and the dual PI3K/mTOR inhibitor PI-103 [31] also efficiently inhibited necroptosis (Fig. 5C).
T9096 268-408 Sentence denotes We found that inhibition of mTORC1 by rapamycin, an inhibitor of the mTOR co-factor Raptor [29], protected cells from necroptosis (Fig. 5C).
T9095 161-267 Sentence denotes An important question is whether these same molecules reverse their pro-survival roles during necroptosis.
T9094 0-160 Sentence denotes Akt kinase is considered to be a pro-survival protein that inhibits apoptosis through the control of multiple effectors including mTORC1, GSK-3 and others [28].
T140 0-160 Sentence denotes Akt kinase is considered to be a pro-survival protein that inhibits apoptosis through the control of multiple effectors including mTORC1, GSK-3 and others [28].
T141 161-267 Sentence denotes An important question is whether these same molecules reverse their pro-survival roles during necroptosis.
T142 268-408 Sentence denotes We found that inhibition of mTORC1 by rapamycin, an inhibitor of the mTOR co-factor Raptor [29], protected cells from necroptosis (Fig. 5C).
T143 409-559 Sentence denotes Similarly, the direct mTOR kinase inhibitor Torin1 [30] and the dual PI3K/mTOR inhibitor PI-103 [31] also efficiently inhibited necroptosis (Fig. 5C).
T144 560-756 Sentence denotes Knockdown of mTOR using siRNA further validated the small-molecule inhibitor data indicating a role for mTOR in necroptosis by protecting cells from both zVAD.fmk and TNFα induced death (Fig. 5D).

simple1

Id Subject Object Predicate Lexical cue
T9350 727-731 Protein denotes TNFα
T9349 352-358 Protein denotes Raptor

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T10218 320-329 Negative_regulation denotes inhibitor
T10188 727-731 Protein denotes TNFα
T10187 352-358 Protein denotes Raptor
R6666 T10187 T10218 themeOf Raptor,inhibitor

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T10475 727-731 Protein denotes TNFα
T10474 352-358 Protein denotes Raptor
T10505 732-739 Positive_regulation denotes induced
T10504 320-329 Negative_regulation denotes inhibitor
R6783 T10474 T10504 themeOf Raptor,inhibitor
R6784 T10475 T10505 themeOf TNFα,induced

DLUT931

Id Subject Object Predicate Lexical cue
T10331 727-731 Protein denotes TNFα
T10330 352-358 Protein denotes Raptor
T10362 732-739 Positive_regulation denotes induced
T10361 320-329 Negative_regulation denotes inhibitor
R6712 T10330 T10361 themeOf Raptor,inhibitor
R6713 T10331 T10362 themeOf TNFα,induced

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T10920 586-589 Protein denotes RNA
T10909 293-302 Entity denotes of mTORC1
T10906 320-407 Entity denotes inhibitor of the mTOR co-factor Raptor [29], protected cells from necroptosis (Fig. 5C)
T10882 664-668 Protein denotes mTOR
T10876 130-136 Entity denotes mTORC1
T10870 352-363 Protein denotes Raptor [29]
T10867 469-509 Protein denotes the dual PI3K/mTOR inhibitor PI-103 [31]
T10866 337-341 Protein denotes mTOR
T10861 0-10 Protein denotes Akt kinase
T10857 747-750 Protein denotes Fig
T10856 443-452 Entity denotes inhibitor
T10855 431-435 Protein denotes mTOR
T10848 573-577 Protein denotes mTOR
T10845 333-407 Entity denotes the mTOR co-factor Raptor [29], protected cells from necroptosis (Fig. 5C)
T10841 443-464 Entity denotes inhibitor Torin1 [30]
T10839 31-159 Protein denotes a pro-survival protein that inhibits apoptosis through the control of multiple effectors including mTORC1, GSK-3 and others [28]
T10835 420-442 Protein denotes the direct mTOR kinase
T10834 0-3 Protein denotes Akt
T10831 698-703 Entity denotes cells
T10830 488-497 Entity denotes inhibitor
T10822 138-143 Protein denotes GSK-3
T10821 627-636 Entity denotes inhibitor
T10820 727-731 Protein denotes TNFα
T10817 303-316 Entity denotes by rapamycin,
T10816 570-586 Entity denotes of mTOR using si
T10811 194-214 Entity denotes these same molecules
T10802 469-509 Entity denotes the dual PI3K/mTOR inhibitor PI-103 [31]
T10796 714-722 Entity denotes zVAD.fmk

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T11323 755-756 . denotes .
T11322 754-755 -RRB- denotes )
T11321 752-754 NNP denotes 5D
T11320 747-751 NNP denotes Fig.
T11319 746-747 -LRB- denotes (
T11318 740-745 NN denotes death
T11317 732-739 VBD denotes induced
T11316 727-731 NNP denotes TNFα
T11315 723-726 CC denotes and
T11314 714-722 NNP denotes zVAD.fmk
T11313 709-713 DT denotes both
T11312 704-708 IN denotes from
T11311 698-703 NNS denotes cells
T11310 687-697 VBG denotes protecting
T11309 684-686 IN denotes by
T11308 672-683 NN denotes necroptosis
T11307 669-671 IN denotes in
T11306 664-668 NNP denotes mTOR
T11305 660-663 IN denotes for
T11304 655-659 NN denotes role
T11291 560-569 NNP denotes Knockdown
T11290 558-559 . denotes .
T11289 557-558 -RRB- denotes )
T11288 555-557 NNP denotes 5C
T11287 550-554 NNP denotes Fig.
T11286 549-550 -LRB- denotes (
T11285 537-548 NN denotes necroptosis
T11284 527-536 VBN denotes inhibited
T11283 515-526 RB denotes efficiently
T11282 510-514 RB denotes also
T11281 508-509 NNP denotes ]
T11280 506-508 CD denotes 31
T11279 505-506 NNP denotes [
T11278 498-504 NN denotes PI-103
T11277 488-497 NN denotes inhibitor
T11276 478-487 JJ denotes PI3K/mTOR
T11275 473-477 JJ denotes dual
T11274 469-472 DT denotes the
T11273 465-468 CC denotes and
T11272 463-464 NNP denotes ]
T11271 461-463 CD denotes 30
T11270 460-461 NNP denotes [
T11269 453-459 NNP denotes Torin1
T11268 443-452 NN denotes inhibitor
T11267 436-442 NN denotes kinase
T11266 431-435 NNP denotes mTOR
T11265 424-430 JJ denotes direct
T11264 420-423 DT denotes the
T11263 418-419 , denotes ,
T11262 409-418 RB denotes Similarly
T11261 407-408 . denotes .
T11260 406-407 -RRB- denotes )
T11259 404-406 NNP denotes 5C
T11258 399-403 NNP denotes Fig.
T11257 398-399 -LRB- denotes (
T11256 386-397 NN denotes necroptosis
T11255 381-385 IN denotes from
T11254 375-380 NNS denotes cells
T11253 365-374 VBN denotes protected
T11252 363-364 , denotes ,
T11251 362-363 NNP denotes ]
T11250 360-362 CD denotes 29
T11249 359-360 NNP denotes [
T11248 352-358 NNP denotes Raptor
T11247 342-351 NN denotes co-factor
T11246 337-341 NNP denotes mTOR
T11245 333-336 DT denotes the
T11244 330-332 IN denotes of
T11243 320-329 NN denotes inhibitor
T11242 317-319 DT denotes an
T11241 315-316 , denotes ,
T11240 306-315 NN denotes rapamycin
T11239 303-305 IN denotes by
T11238 296-302 NNP denotes mTORC1
T11237 293-295 IN denotes of
T11236 282-292 NN denotes inhibition
T11235 277-281 IN denotes that
T11234 271-276 VBD denotes found
T11233 268-270 PRP denotes We
T11232 266-267 . denotes .
T11231 255-266 NN denotes necroptosis
T11230 248-254 IN denotes during
T11229 242-247 NNS denotes roles
T11228 229-241 JJ denotes pro-survival
T11227 223-228 PRP$ denotes their
T11226 215-222 VBP denotes reverse
T11225 205-214 NNS denotes molecules
T11224 200-204 JJ denotes same
T11223 194-199 DT denotes these
T11222 186-193 IN denotes whether
T11221 183-185 VBZ denotes is
T11220 174-182 NN denotes question
T11219 164-173 JJ denotes important
T11218 161-163 DT denotes An
T11217 159-160 . denotes .
T11216 158-159 NNP denotes ]
T11215 156-158 CD denotes 28
T11214 155-156 NNP denotes [
T11213 148-154 NNS denotes others
T11212 144-147 CC denotes and
T11211 138-143 NNP denotes GSK-3
T11210 136-137 , denotes ,
T11209 130-136 NNP denotes mTORC1
T11208 120-129 VBG denotes including
T11207 110-119 NNS denotes effectors
T11206 101-109 JJ denotes multiple
T11205 98-100 IN denotes of
T11204 90-97 NN denotes control
T11203 86-89 DT denotes the
T11202 78-85 IN denotes through
T11201 68-77 NN denotes apoptosis
T11200 59-67 VBZ denotes inhibits
T11199 54-58 WDT denotes that
T11198 46-53 NN denotes protein
T11197 33-45 JJ denotes pro-survival
T11196 31-32 DT denotes a
T11195 28-30 VB denotes be
T11194 25-27 TO denotes to
T11193 14-24 VBN denotes considered
T11192 11-13 VBZ denotes is
T11191 4-10 NN denotes kinase
T11190 0-3 NNP denotes Akt
T11303 653-654 DT denotes a
T11302 642-652 VBG denotes indicating
T11301 637-641 NNS denotes data
T11300 627-636 NN denotes inhibitor
T11299 612-626 JJ denotes small-molecule
T11298 608-611 DT denotes the
T11297 598-607 VBD denotes validated
T11296 590-597 JJ denotes further
T11295 584-589 NNP denotes siRNA
T11294 578-583 VBG denotes using
T11293 573-577 NNP denotes mTOR
T11292 570-572 IN denotes of
R7227 T11190 T11191 compound Akt,kinase
R7228 T11191 T11193 nsubjpass kinase,considered
R7229 T11192 T11193 auxpass is,considered
R7230 T11193 T11193 ROOT considered,considered
R7231 T11194 T11195 aux to,be
R7232 T11195 T11193 xcomp be,considered
R7233 T11196 T11198 det a,protein
R7234 T11197 T11198 amod pro-survival,protein
R7235 T11198 T11195 attr protein,be
R7236 T11199 T11200 nsubj that,inhibits
R7237 T11200 T11198 relcl inhibits,protein
R7238 T11201 T11200 dobj apoptosis,inhibits
R7239 T11202 T11200 prep through,inhibits
R7240 T11203 T11204 det the,control
R7241 T11204 T11202 pobj control,through
R7242 T11205 T11204 prep of,control
R7243 T11206 T11207 amod multiple,effectors
R7244 T11207 T11205 pobj effectors,of
R7245 T11208 T11207 prep including,effectors
R7246 T11209 T11208 pobj mTORC1,including
R7247 T11210 T11209 punct ",",mTORC1
R7248 T11211 T11209 conj GSK-3,mTORC1
R7249 T11212 T11211 cc and,GSK-3
R7250 T11213 T11211 conj others,GSK-3
R7251 T11214 T11216 nmod [,]
R7252 T11215 T11216 nummod 28,]
R7253 T11216 T11213 appos ],others
R7254 T11217 T11193 punct .,considered
R7255 T11218 T11220 det An,question
R7256 T11219 T11220 amod important,question
R7257 T11220 T11221 nsubj question,is
R7258 T11221 T11221 ROOT is,is
R7259 T11222 T11226 mark whether,reverse
R7260 T11223 T11225 det these,molecules
R7261 T11224 T11225 amod same,molecules
R7262 T11225 T11226 nsubj molecules,reverse
R7263 T11226 T11221 ccomp reverse,is
R7264 T11227 T11229 poss their,roles
R7265 T11228 T11229 amod pro-survival,roles
R7266 T11229 T11226 dobj roles,reverse
R7267 T11230 T11226 prep during,reverse
R7268 T11231 T11230 pobj necroptosis,during
R7269 T11232 T11221 punct .,is
R7270 T11233 T11234 nsubj We,found
R7271 T11234 T11234 ROOT found,found
R7272 T11235 T11236 det that,inhibition
R7273 T11236 T11234 dobj inhibition,found
R7274 T11237 T11236 prep of,inhibition
R7275 T11238 T11237 pobj mTORC1,of
R7276 T11239 T11236 prep by,inhibition
R7277 T11240 T11239 pobj rapamycin,by
R7278 T11241 T11240 punct ",",rapamycin
R7279 T11242 T11243 det an,inhibitor
R7280 T11243 T11236 conj inhibitor,inhibition
R7281 T11244 T11243 prep of,inhibitor
R7282 T11245 T11247 det the,co-factor
R7283 T11246 T11247 compound mTOR,co-factor
R7284 T11247 T11244 pobj co-factor,of
R7285 T11248 T11249 compound Raptor,[
R7286 T11249 T11247 appos [,co-factor
R7287 T11250 T11251 nummod 29,]
R7288 T11251 T11247 appos ],co-factor
R7289 T11252 T11251 punct ",",]
R7290 T11253 T11254 amod protected,cells
R7291 T11254 T11247 appos cells,co-factor
R7294 T11257 T11256 punct (,necroptosis
R7295 T11258 T11259 compound Fig.,5C
R7296 T11259 T11256 appos 5C,necroptosis
R7297 T11260 T11256 punct ),necroptosis
R7298 T11261 T11234 punct .,found
R7299 T11262 T11284 advmod Similarly,inhibited
R7300 T11263 T11284 punct ",",inhibited
R7301 T11264 T11268 det the,inhibitor
R7302 T11265 T11268 amod direct,inhibitor
R7303 T11266 T11268 compound mTOR,inhibitor
R7304 T11267 T11268 compound kinase,inhibitor
R7305 T11268 T11284 nsubj inhibitor,inhibited
R7306 T11269 T11270 compound Torin1,[
R7307 T11270 T11268 appos [,inhibitor
R7308 T11271 T11272 nummod 30,]
R7309 T11272 T11270 appos ],[
R7310 T11273 T11272 cc and,]
R7311 T11274 T11277 det the,inhibitor
R7312 T11275 T11277 amod dual,inhibitor
R7313 T11276 T11277 amod PI3K/mTOR,inhibitor
R7314 T11277 T11278 compound inhibitor,PI-103
R7315 T11278 T11279 compound PI-103,[
R7316 T11279 T11281 compound [,]
R7317 T11280 T11281 compound 31,]
R7318 T11281 T11272 conj ],]
R7319 T11282 T11284 advmod also,inhibited
R7320 T11283 T11284 advmod efficiently,inhibited
R7321 T11284 T11284 ROOT inhibited,inhibited
R7322 T11285 T11284 dobj necroptosis,inhibited
R7323 T11286 T11288 punct (,5C
R7324 T11287 T11288 compound Fig.,5C
R7325 T11288 T11285 appos 5C,necroptosis
R7326 T11289 T11288 punct ),5C
R7327 T11290 T11284 punct .,inhibited
R7328 T11291 T11297 nsubj Knockdown,validated
R7329 T11292 T11291 prep of,Knockdown
R7330 T11293 T11292 pobj mTOR,of
R7331 T11294 T11297 nsubj using,validated
R7332 T11295 T11296 compound siRNA,further
R7333 T11296 T11297 advmod further,validated
R7334 T11297 T11297 ROOT validated,validated
R7335 T11298 T11301 det the,data
R7336 T11299 T11301 amod small-molecule,data
R7337 T11300 T11301 compound inhibitor,data
R7338 T11301 T11297 dobj data,validated
R7339 T11302 T11301 acl indicating,data
R7340 T11303 T11304 det a,role
R7341 T11304 T11302 dobj role,indicating
R7342 T11305 T11304 prep for,role
R7343 T11306 T11305 pobj mTOR,for
R7344 T11307 T11304 prep in,role
R7345 T11308 T11307 pobj necroptosis,in
R7346 T11309 T11304 prep by,role
R7347 T11310 T11309 pcomp protecting,by
R7348 T11311 T11310 dobj cells,protecting
R7349 T11312 T11310 prep from,protecting
R7350 T11313 T11314 preconj both,zVAD.fmk
R7351 T11314 T11312 pobj zVAD.fmk,from
R7352 T11315 T11314 cc and,zVAD.fmk
R7353 T11316 T11314 conj TNFα,zVAD.fmk
R7354 T11317 T11297 conj induced,validated
R7355 T11318 T11317 dobj death,induced
R7356 T11319 T11321 punct (,5D
R7357 T11320 T11321 compound Fig.,5D
R7358 T11321 T11317 oprd 5D,induced
R7359 T11322 T11321 punct ),5D
R7360 T11323 T11297 punct .,validated
R7292 T11255 T11254 prep from,cells
R7293 T11256 T11255 pobj necroptosis,from

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T10580 560-569 Negative_regulation denotes Knockdown
T10579 727-731 Protein denotes TNFα
T10578 714-722 Protein denotes zVAD.fmk
T10577 664-668 Protein denotes mTOR
T10576 573-589 Protein denotes mTOR using siRNA
T10575 488-497 Negative_regulation denotes inhibitor
T10574 488-497 Negative_regulation denotes inhibitor
T10573 443-452 Negative_regulation denotes inhibitor
T10572 483-487 Protein denotes mTOR
T10571 478-482 Protein denotes PI3K
T10570 431-442 Protein denotes mTOR kinase
T10569 320-329 Negative_regulation denotes inhibitor
T10568 282-292 Negative_regulation denotes inhibition
T10567 337-341 Protein denotes mTOR
T10566 296-302 Protein denotes mTORC1
T10565 0-10 Protein denotes Akt kinase
R6827 T10566 T10568 themeOf mTORC1,inhibition
R6828 T10567 T10569 themeOf mTOR,inhibitor
R6829 T10570 T10573 themeOf mTOR kinase,inhibitor
R6830 T10571 T10574 themeOf PI3K,inhibitor
R6831 T10572 T10575 themeOf mTOR,inhibitor
R6832 T10576 T10580 themeOf mTOR using siRNA,Knockdown

test3

Id Subject Object Predicate Lexical cue
T8980 727-731 Protein denotes TNFα
T8979 352-358 Protein denotes Raptor
T9035 732-739 Positive_regulation denotes induced
T9034 727-731 Protein denotes TNFα
T9033 560-569 Negative_regulation denotes Knockdown
T9032 527-536 Negative_regulation denotes inhibited
T9031 488-497 Negative_regulation denotes inhibitor
T9030 443-452 Negative_regulation denotes inhibitor
T9029 352-358 Protein denotes Raptor
T9028 320-329 Negative_regulation denotes inhibitor
R5834 T9029 T9028 themeOf Raptor,inhibitor