PMC:3585731 / 20043-20329 JSONTXT

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{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T9202","span":{"begin":272,"end":274},"obj":"Protein"},{"id":"T9201","span":{"begin":263,"end":269},"obj":"Protein"},{"id":"T9200","span":{"begin":230,"end":261},"obj":"Protein"},{"id":"T9199","span":{"begin":190,"end":194},"obj":"Protein"},{"id":"T9198","span":{"begin":173,"end":188},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Under necroptotic conditions, we observed an increase in the phosphorylation of multiple known Akt substrates (Forkhead box class O (FoxO) proteins, GSK-3 kinases and mouse double minute 2 (MDM2)) as well as downstream molecules (p70 ribosomal protein S6 Kinase (p70S6K), S6) (Fig. 5A)."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T10263","span":{"begin":95,"end":98},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T10249","span":{"begin":95,"end":98},"obj":"http://www.uniprot.org/uniprot/P31749"},{"id":"T10277","span":{"begin":95,"end":98},"obj":"http://www.uniprot.org/uniprot/Q9Y243"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Under necroptotic conditions, we observed an increase in the phosphorylation of multiple known Akt substrates (Forkhead box class O (FoxO) proteins, GSK-3 kinases and mouse double minute 2 (MDM2)) as well as downstream molecules (p70 ribosomal protein S6 Kinase (p70S6K), S6) (Fig. 5A)."}

{"project":"GO-BP","denotations":[{"id":"T9290","span":{"begin":149,"end":152},"obj":"http://purl.obolibrary.org/obo/GO_0050321"},{"id":"T9284","span":{"begin":61,"end":76},"obj":"http://purl.obolibrary.org/obo/GO_0016310"}],"text":"Under necroptotic conditions, we observed an increase in the phosphorylation of multiple known Akt substrates (Forkhead box class O (FoxO) proteins, GSK-3 kinases and mouse double minute 2 (MDM2)) as well as downstream molecules (p70 ribosomal protein S6 Kinase (p70S6K), S6) (Fig. 5A)."}

{"project":"GO-MF","denotations":[{"id":"T9317","span":{"begin":234,"end":251},"obj":"http://purl.obolibrary.org/obo/GO_0003735"},{"id":"T9314","span":{"begin":149,"end":152},"obj":"http://purl.obolibrary.org/obo/GO_0050321"}],"text":"Under necroptotic conditions, we observed an increase in the phosphorylation of multiple known Akt substrates (Forkhead box class O (FoxO) proteins, GSK-3 kinases and mouse double minute 2 (MDM2)) as well as downstream molecules (p70 ribosomal protein S6 Kinase (p70S6K), S6) (Fig. 5A)."}

{"project":"sentences","denotations":[{"id":"T9087","span":{"begin":0,"end":286},"obj":"Sentence"},{"id":"T128","span":{"begin":0,"end":286},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Under necroptotic conditions, we observed an increase in the phosphorylation of multiple known Akt substrates (Forkhead box class O (FoxO) proteins, GSK-3 kinases and mouse double minute 2 (MDM2)) as well as downstream molecules (p70 ribosomal protein S6 Kinase (p70S6K), S6) (Fig. 5A)."}

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