PMC:3585731 / 13741-13881 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3585731","sourcedb":"PMC","sourceid":"3585731","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3585731","text":"The RIP1 kinase inhibitor, Nec-1, completely prevented the increase in Thr308 Akt phosphorylation, while Nec-1i did not (Fig. 3A, Fig. S1D).","tracks":[{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T6507","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T6479","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T6430","span":{"begin":4,"end":8},"obj":"http://www.uniprot.org/uniprot/Q13546"},{"id":"T6451","span":{"begin":78,"end":81},"obj":"http://www.uniprot.org/uniprot/P31749"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"attributes":[{"subj":"T6507","pred":"source","obj":"bionlp-st-ge-2016-uniprot"},{"subj":"T6479","pred":"source","obj":"bionlp-st-ge-2016-uniprot"},{"subj":"T6430","pred":"source","obj":"bionlp-st-ge-2016-uniprot"},{"subj":"T6451","pred":"source","obj":"bionlp-st-ge-2016-uniprot"}]},{"project":"pmc-enju-pas","denotations":[{"id":"T6028","span":{"begin":138,"end":139},"obj":"-RRB-"},{"id":"T6027","span":{"begin":135,"end":138},"obj":"NN"},{"id":"T6026","span":{"begin":130,"end":134},"obj":"NNP"},{"id":"T6025","span":{"begin":128,"end":129},"obj":"-COMMA-"},{"id":"T6024","span":{"begin":126,"end":128},"obj":"NNP"},{"id":"T6023","span":{"begin":121,"end":125},"obj":"NNP"},{"id":"T6022","span":{"begin":120,"end":121},"obj":"-LRB-"},{"id":"T6021","span":{"begin":116,"end":119},"obj":"RB"},{"id":"T6020","span":{"begin":112,"end":115},"obj":"VB"},{"id":"T6019","span":{"begin":105,"end":111},"obj":"NN"},{"id":"T6018","span":{"begin":99,"end":104},"obj":"IN"},{"id":"T6017","span":{"begin":97,"end":98},"obj":"-COMMA-"},{"id":"T6016","span":{"begin":82,"end":97},"obj":"NN"},{"id":"T6015","span":{"begin":78,"end":81},"obj":"NN"},{"id":"T6014","span":{"begin":71,"end":77},"obj":"NN"},{"id":"T6013","span":{"begin":68,"end":70},"obj":"IN"},{"id":"T6012","span":{"begin":59,"end":67},"obj":"NN"},{"id":"T6011","span":{"begin":55,"end":58},"obj":"DT"},{"id":"T6010","span":{"begin":45,"end":54},"obj":"VB"},{"id":"T6009","span":{"begin":34,"end":44},"obj":"RB"},{"id":"T6008","span":{"begin":32,"end":33},"obj":"-COMMA-"},{"id":"T6007","span":{"begin":27,"end":32},"obj":"NN"},{"id":"T6006","span":{"begin":25,"end":26},"obj":"-COMMA-"},{"id":"T6005","span":{"begin":16,"end":25},"obj":"NN"},{"id":"T6004","span":{"begin":9,"end":15},"obj":"NN"},{"id":"T6003","span":{"begin":4,"end":8},"obj":"NN"},{"id":"T6002","span":{"begin":0,"end":3},"obj":"DT"}],"relations":[{"id":"R4054","pred":"arg1Of","subj":"T6005","obj":"T6002"},{"id":"R4055","pred":"arg1Of","subj":"T6005","obj":"T6003"},{"id":"R4056","pred":"arg1Of","subj":"T6005","obj":"T6004"},{"id":"R4057","pred":"arg1Of","subj":"T6005","obj":"T6006"},{"id":"R4058","pred":"arg1Of","subj":"T6005","obj":"T6010"},{"id":"R4059","pred":"arg2Of","subj":"T6007","obj":"T6006"},{"id":"R4060","pred":"arg1Of","subj":"T6010","obj":"T6008"},{"id":"R4061","pred":"arg1Of","subj":"T6010","obj":"T6009"},{"id":"R4062","pred":"arg1Of","subj":"T6010","obj":"T6017"},{"id":"R4063","pred":"arg1Of","subj":"T6010","obj":"T6018"},{"id":"R4064","pred":"arg2Of","subj":"T6012","obj":"T6010"},{"id":"R4065","pred":"arg1Of","subj":"T6012","obj":"T6011"},{"id":"R4066","pred":"arg1Of","subj":"T6012","obj":"T6013"},{"id":"R4067","pred":"arg2Of","subj":"T6016","obj":"T6013"},{"id":"R4068","pred":"arg1Of","subj":"T6016","obj":"T6014"},{"id":"R4069","pred":"arg1Of","subj":"T6016","obj":"T6015"},{"id":"R4070","pred":"arg1Of","subj":"T6019","obj":"T6020"},{"id":"R4071","pred":"arg2Of","subj":"T6020","obj":"T6018"},{"id":"R4072","pred":"arg1Of","subj":"T6020","obj":"T6021"},{"id":"R4073","pred":"arg1Of","subj":"T6020","obj":"T6022"},{"id":"R4074","pred":"arg2Of","subj":"T6024","obj":"T6022"},{"id":"R4075","pred":"arg1Of","subj":"T6024","obj":"T6023"},{"id":"R4076","pred":"arg1Of","subj":"T6024","obj":"T6025"},{"id":"R4077","pred":"arg2Of","subj":"T6027","obj":"T6025"},{"id":"R4078","pred":"arg1Of","subj":"T6027","obj":"T6026"},{"id":"R4079","pred":"arg3Of","subj":"T6028","obj":"T6022"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"attributes":[{"subj":"T6028","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6027","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6026","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6025","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6024","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6023","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6022","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6021","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6020","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6019","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6018","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6017","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6016","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6015","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6014","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6013","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6012","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6011","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6010","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6009","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6008","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6007","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6006","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6005","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6004","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6003","pred":"source","obj":"pmc-enju-pas"},{"subj":"T6002","pred":"source","obj":"pmc-enju-pas"}]},{"project":"sentences","denotations":[{"id":"T5297","span":{"begin":0,"end":140},"obj":"Sentence"},{"id":"T88","span":{"begin":0,"end":140},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T5297","pred":"source","obj":"sentences"},{"subj":"T88","pred":"source","obj":"sentences"}]},{"project":"GO-BP","denotations":[{"id":"T5467","span":{"begin":82,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T5462","span":{"begin":9,"end":25},"obj":"http://purl.obolibrary.org/obo/GO_0033673"}],"attributes":[{"subj":"T5467","pred":"source","obj":"GO-BP"},{"subj":"T5462","pred":"source","obj":"GO-BP"}]},{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T5384","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T5383","span":{"begin":4,"end":8},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"attributes":[{"subj":"T5384","pred":"source","obj":"bionlp-st-ge-2016-test-proteins"},{"subj":"T5383","pred":"source","obj":"bionlp-st-ge-2016-test-proteins"}]},{"project":"simple1","denotations":[{"id":"T5537","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T5536","span":{"begin":4,"end":8},"obj":"Protein"}],"attributes":[{"subj":"T5537","pred":"source","obj":"simple1"},{"subj":"T5536","pred":"source","obj":"simple1"}]},{"project":"DLUT931","denotations":[{"id":"T6584","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T6583","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T6582","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T6581","span":{"begin":16,"end":25},"obj":"Negative_regulation"},{"id":"T6557","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T6556","span":{"begin":4,"end":8},"obj":"Protein"}],"relations":[{"id":"R4432","pred":"themeOf","subj":"T6556","obj":"T6581"},{"id":"R4433","pred":"themeOf","subj":"T6557","obj":"T6582"},{"id":"R4447","pred":"causeOf","subj":"T6581","obj":"T6584"},{"id":"R4448","pred":"themeOf","subj":"T6582","obj":"T6583"},{"id":"R4449","pred":"themeOf","subj":"T6583","obj":"T6584"}],"attributes":[{"subj":"T6584","pred":"source","obj":"DLUT931"},{"subj":"T6583","pred":"source","obj":"DLUT931"},{"subj":"T6582","pred":"source","obj":"DLUT931"},{"subj":"T6581","pred":"source","obj":"DLUT931"},{"subj":"T6557","pred":"source","obj":"DLUT931"},{"subj":"T6556","pred":"source","obj":"DLUT931"}]},{"project":"BioNLP16_DUT","denotations":[{"id":"T6420","span":{"begin":16,"end":25},"obj":"Negative_regulation"},{"id":"T6419","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T6418","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T6417","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T6396","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T6395","span":{"begin":4,"end":8},"obj":"Protein"}],"relations":[{"id":"R4407","pred":"themeOf","subj":"T6395","obj":"T6420"},{"id":"R4408","pred":"themeOf","subj":"T6396","obj":"T6418"},{"id":"R4418","pred":"themeOf","subj":"T6418","obj":"T6419"},{"id":"R4419","pred":"themeOf","subj":"T6419","obj":"T6417"}],"attributes":[{"subj":"T6420","pred":"source","obj":"BioNLP16_DUT"},{"subj":"T6419","pred":"source","obj":"BioNLP16_DUT"},{"subj":"T6418","pred":"source","obj":"BioNLP16_DUT"},{"subj":"T6417","pred":"source","obj":"BioNLP16_DUT"},{"subj":"T6396","pred":"source","obj":"BioNLP16_DUT"},{"subj":"T6395","pred":"source","obj":"BioNLP16_DUT"}]},{"project":"BioNLP16_Messiy","denotations":[{"id":"T6704","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T6703","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T6702","span":{"begin":16,"end":25},"obj":"Negative_regulation"},{"id":"T6701","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T6677","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T6676","span":{"begin":4,"end":8},"obj":"Protein"}],"relations":[{"id":"R4487","pred":"themeOf","subj":"T6676","obj":"T6702"},{"id":"R4488","pred":"themeOf","subj":"T6677","obj":"T6704"},{"id":"R4495","pred":"themeOf","subj":"T6701","obj":"T6703"},{"id":"R4496","pred":"causeOf","subj":"T6702","obj":"T6703"},{"id":"R4497","pred":"themeOf","subj":"T6704","obj":"T6701"}],"attributes":[{"subj":"T6704","pred":"source","obj":"BioNLP16_Messiy"},{"subj":"T6703","pred":"source","obj":"BioNLP16_Messiy"},{"subj":"T6702","pred":"source","obj":"BioNLP16_Messiy"},{"subj":"T6701","pred":"source","obj":"BioNLP16_Messiy"},{"subj":"T6677","pred":"source","obj":"BioNLP16_Messiy"},{"subj":"T6676","pred":"source","obj":"BioNLP16_Messiy"}]},{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T7307","span":{"begin":27,"end":98},"obj":"Negative_regulation"},{"id":"T7303","span":{"begin":68,"end":97},"obj":"Phosphorylation"},{"id":"T7301","span":{"begin":55,"end":98},"obj":"Positive_regulation"},{"id":"T7253","span":{"begin":27,"end":32},"obj":"Protein"},{"id":"T7210","span":{"begin":0,"end":26},"obj":"Protein"},{"id":"T7199","span":{"begin":0,"end":26},"obj":"Entity"},{"id":"T7175","span":{"begin":71,"end":77},"obj":"Entity"},{"id":"T7159","span":{"begin":0,"end":26},"obj":"Protein"},{"id":"T7156","span":{"begin":71,"end":81},"obj":"Protein"}],"relations":[{"id":"R4704","pred":"themeOf","subj":"T7156","obj":"T7303"},{"id":"R4719","pred":"partOf","subj":"T7175","obj":"T7156"},{"id":"R4720","pred":"siteOf","subj":"T7175","obj":"T7303"},{"id":"R4759","pred":"causeOf","subj":"T7253","obj":"T7307"},{"id":"R4778","pred":"themeOf","subj":"T7301","obj":"T7307"},{"id":"R4779","pred":"themeOf","subj":"T7303","obj":"T7301"}],"attributes":[{"subj":"T7307","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7303","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7301","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7253","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7210","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7199","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7175","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7159","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T7156","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"}]},{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T6807","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T6806","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T6805","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T6804","span":{"begin":135,"end":138},"obj":"Protein"},{"id":"T6803","span":{"begin":130,"end":133},"obj":"Protein"},{"id":"T6802","span":{"begin":121,"end":128},"obj":"Protein"},{"id":"T6801","span":{"begin":105,"end":111},"obj":"Protein"},{"id":"T6800","span":{"begin":71,"end":81},"obj":"Protein"},{"id":"T6799","span":{"begin":27,"end":32},"obj":"Protein"},{"id":"T6798","span":{"begin":4,"end":15},"obj":"Protein"}],"relations":[{"id":"R4540","pred":"causeOf","subj":"T6799","obj":"T6807"},{"id":"R4542","pred":"themeOf","subj":"T6800","obj":"T6805"},{"id":"R4544","pred":"themeOf","subj":"T6805","obj":"T6806"},{"id":"R4546","pred":"themeOf","subj":"T6806","obj":"T6807"}],"attributes":[{"subj":"T6807","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6806","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6805","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6804","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6803","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6802","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6801","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6800","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6799","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T6798","pred":"source","obj":"bionlp-st-ge-2016-test-tees"}]},{"project":"testone","denotations":[{"id":"T5118","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T5117","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T5116","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T5115","span":{"begin":16,"end":25},"obj":"Negative_regulation"},{"id":"T5073","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T5072","span":{"begin":4,"end":8},"obj":"Protein"}],"relations":[{"id":"R3505","pred":"themeOf","subj":"T5072","obj":"T5115"},{"id":"R3506","pred":"themeOf","subj":"T5073","obj":"T5118"},{"id":"R3521","pred":"causeOf","subj":"T5115","obj":"T5116"},{"id":"R3522","pred":"themeOf","subj":"T5117","obj":"T5116"},{"id":"R3523","pred":"themeOf","subj":"T5118","obj":"T5117"}],"attributes":[{"subj":"T5118","pred":"source","obj":"testone"},{"subj":"T5117","pred":"source","obj":"testone"},{"subj":"T5116","pred":"source","obj":"testone"},{"subj":"T5115","pred":"source","obj":"testone"},{"subj":"T5073","pred":"source","obj":"testone"},{"subj":"T5072","pred":"source","obj":"testone"}]},{"project":"test3","denotations":[{"id":"T5229","span":{"begin":82,"end":97},"obj":"Phosphorylation"},{"id":"T5228","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T5227","span":{"begin":59,"end":67},"obj":"Positive_regulation"},{"id":"T5226","span":{"begin":45,"end":54},"obj":"Negative_regulation"},{"id":"T5225","span":{"begin":16,"end":25},"obj":"Negative_regulation"},{"id":"T5224","span":{"begin":4,"end":8},"obj":"Protein"},{"id":"T5169","span":{"begin":78,"end":81},"obj":"Protein"},{"id":"T5168","span":{"begin":4,"end":8},"obj":"Protein"}],"relations":[{"id":"R3551","pred":"themeOf","subj":"T5224","obj":"T5225"},{"id":"R3552","pred":"causeOf","subj":"T5225","obj":"T5227"},{"id":"R3553","pred":"causeOf","subj":"T5225","obj":"T5226"},{"id":"R3554","pred":"themeOf","subj":"T5227","obj":"T5226"},{"id":"R3555","pred":"themeOf","subj":"T5228","obj":"T5229"},{"id":"R3556","pred":"themeOf","subj":"T5229","obj":"T5227"}],"attributes":[{"subj":"T5229","pred":"source","obj":"test3"},{"subj":"T5228","pred":"source","obj":"test3"},{"subj":"T5227","pred":"source","obj":"test3"},{"subj":"T5226","pred":"source","obj":"test3"},{"subj":"T5225","pred":"source","obj":"test3"},{"subj":"T5224","pred":"source","obj":"test3"},{"subj":"T5169","pred":"source","obj":"test3"},{"subj":"T5168","pred":"source","obj":"test3"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-st-ge-2016-uniprot","color":"#93ecd1","default":true},{"id":"pmc-enju-pas","color":"#ecb793"},{"id":"sentences","color":"#9d93ec"},{"id":"GO-BP","color":"#a3ec93"},{"id":"bionlp-st-ge-2016-test-proteins","color":"#ec93bd"},{"id":"simple1","color":"#93d7ec"},{"id":"DLUT931","color":"#ece793"},{"id":"BioNLP16_DUT","color":"#cd93ec"},{"id":"BioNLP16_Messiy","color":"#93ecb3"},{"id":"bionlp-st-ge-2016-test-ihmc","color":"#ec9993"},{"id":"bionlp-st-ge-2016-test-tees","color":"#93a6ec"},{"id":"testone","color":"#c0ec93"},{"id":"test3","color":"#ec93da"}]}]}}