Table 1  Number of cases required to achieve 80% power according to the different genetic models in a case-control study   Assumptions: 5% minor allele frequency, 5% disease prevalence, complete linkage disequilibrium (D'=1), 1:1 case-control ratio, and 5% type I error rates for single marker analyses.
ORhet/ORhomo, odds ratios of heterozygotes/rare homozygotes.