Table 1 Class comparison of ortholog conservation in cellular organismsa Values of conservation state are presented as percentage. aEach class (see the caption of Fig. 2 for abbreviations of classes) consists of several orthologs and it follows the reference pathway of KEGG Ortholog (KO); b+ symbol denotes the maximum percentage of KO that have orthologs in each Class: 0% < (+) ≤ 25%, 25% < (++) ≤ 50%, 50% < (+++) ≤ 75%, 75% < (++++) ≤ 100%; cMaximum percentage of KO; dAverage percentage of participating KOs in the pathway.