Definition 6 (Pattern information) Given a pattern P = P1, P2, ..., Pq and a DNA sequence database D, the pattern information of P in D is defined as I(P) = -log|C|Pr(P,D) = I(P1) + I(P2) +......+ I(Pq). For example, the pattern information of pattern "ATCG" is I(ATCG,D) = I(A,D) + I(T,D) + I(C,D) + I(G,D) = 1.228 + 0.713 + 1.098 + 0.9365 = 3.9755 in Table 1.