PMC:3359311 / 1341-1502 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T373	107-112	P01584	denotes	IL-1β
T374	116-120	P10145	denotes	IL-8

Id	Subject	Object	Predicate	Lexical cue	Negation
T59	101-106	Regulation	denotes	alter	true
T60	107-112	Protein	denotes	IL-1β
T61	121-131	Gene_expression	denotes	production
T62	132-146	Positive_regulation	denotes	in response to
R36	T60	T61	themeOf	IL-1β,production
R37	T61	T62	themeOf	production,in response to
R38	T62	T59	themeOf	in response to,alter

Id	Subject	Object	Predicate	Lexical cue
T828	32-36	Protein	denotes	CFTR
T829	107-112	Protein	denotes	IL-1β
T830	116-120	Protein	denotes	IL-8
T831	18-28	Negative_regulation	denotes	inhibition
T832	121-131	Gene_expression	denotes	production
T833	121-131	Gene_expression	denotes	production
T834	101-106	Positive_regulation	denotes	alter
T835	101-106	Positive_regulation	denotes	alter
R681	T828	T831	themeOf	CFTR,inhibition
R682	T829	T832	themeOf	IL-1β,production
R683	T830	T833	themeOf	IL-8,production
R684	T832	T834	themeOf	production,alter
R685	T833	T835	themeOf	production,alter

Id	Subject	Object	Predicate	Lexical cue	Negation
T789	101-106	Regulation	denotes	alter	true
T790	107-112	Protein	denotes	IL-1β
T791	121-131	Gene_expression	denotes	production
T792	132-146	Positive_regulation	denotes	in response to
R658	T790	T791	themeOf	IL-1β,production
R659	T791	T792	themeOf	production,in response to
R660	T792	T789	themeOf	in response to,alter

Id	Subject	Object	Predicate	Lexical cue
T692	73-78	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

Id	Subject	Object	Predicate	Lexical cue
T696	116-120	http://purl.obolibrary.org/obo/GO_0005153	denotes	IL-8

Id	Subject	Object	Predicate	Lexical cue
T686	116-131	http://purl.obolibrary.org/obo/GO_0032677	denotes	IL-8 production
T687	116-131	http://purl.obolibrary.org/obo/GO_0032637	denotes	IL-8 production

Id	Subject	Object	Predicate	Lexical cue
T568	0-7	RB	denotes	Finally
T569	7-8	,	denotes	,
T570	9-17	NN	denotes	chemical
T571	18-28	NN	denotes	inhibition
T572	29-31	IN	denotes	of
T573	32-36	NNP	denotes	CFTR
T574	37-45	NN	denotes	activity
T575	46-48	IN	denotes	in
T576	49-56	NN	denotes	control
T577	57-62	NNS	denotes	PBMCs
T578	63-66	CC	denotes	and
T579	67-72	CD	denotes	THP-1
T580	73-78	NNS	denotes	cells
T581	79-82	VBD	denotes	did
T582	83-86	RB	denotes	not
T583	87-100	RB	denotes	significantly
T584	101-106	VB	denotes	alter
T585	107-112	JJ	denotes	IL-1β
T586	113-115	CC	denotes	or
T587	116-120	JJ	denotes	IL-8
T588	121-131	NN	denotes	production
T589	132-134	IN	denotes	in
T590	135-143	NN	denotes	response
T591	144-146	TO	denotes	to
T592	147-149	NNP	denotes	P.
T593	150-160	NN	denotes	aeruginosa
T594	160-161	.	denotes	.
R506	T568	T584	advmod	Finally,alter
R507	T569	T584	punct	",",alter
R508	T570	T571	compound	chemical,inhibition
R509	T571	T584	nsubj	inhibition,alter
R510	T572	T571	prep	of,inhibition
R511	T573	T574	amod	CFTR,activity
R512	T574	T572	pobj	activity,of
R513	T575	T574	prep	in,activity
R514	T576	T575	pobj	control,in
R515	T577	T571	conj	PBMCs,inhibition
R516	T578	T577	cc	and,PBMCs
R517	T579	T580	nummod	THP-1,cells
R518	T580	T577	conj	cells,PBMCs
R519	T581	T584	aux	did,alter
R520	T582	T584	neg	not,alter
R521	T583	T584	advmod	significantly,alter
R522	T584	T584	ROOT	alter,alter
R523	T585	T588	amod	IL-1β,production
R524	T586	T585	cc	or,IL-1β
R525	T587	T585	conj	IL-8,IL-1β
R526	T588	T584	dobj	production,alter
R527	T589	T584	prep	in,alter
R528	T590	T589	pobj	response,in
R529	T591	T590	prep	to,response
R530	T592	T593	compound	P.,aeruginosa
R531	T593	T591	pobj	aeruginosa,to
R532	T594	T584	punct	.,alter

Id	Subject	Object	Predicate	Lexical cue
T271	0-7	RB	denotes	Finally
T272	7-8	-COMMA-	denotes	,
T273	9-17	JJ	denotes	chemical
T274	18-28	NN	denotes	inhibition
T275	29-31	IN	denotes	of
T276	32-36	NN	denotes	CFTR
T277	37-45	NN	denotes	activity
T278	46-48	IN	denotes	in
T279	49-56	NN	denotes	control
T280	57-62	NN	denotes	PBMCs
T281	63-66	CC	denotes	and
T282	67-72	NN	denotes	THP-1
T283	73-78	NN	denotes	cells
T284	79-82	VB	denotes	did
T285	83-86	RB	denotes	not
T286	87-100	RB	denotes	significantly
T287	101-106	VB	denotes	alter
T288	107-112	NN	denotes	IL-1β
T289	113-115	CC	denotes	or
T290	116-120	NN	denotes	IL-8
T291	121-131	NN	denotes	production
T292	132-134	IN	denotes	in
T293	135-143	NN	denotes	response
T294	144-146	TO	denotes	to
T295	147-149	NNP	denotes	P.
T296	150-160	NN	denotes	aeruginosa
R224	T274	T273	arg1Of	inhibition,chemical
R225	T274	T275	arg1Of	inhibition,of
R226	T274	T278	arg1Of	inhibition,in
R227	T274	T284	arg1Of	inhibition,did
R228	T274	T287	arg1Of	inhibition,alter
R229	T277	T275	arg2Of	activity,of
R230	T277	T276	arg1Of	activity,CFTR
R231	T280	T279	arg1Of	PBMCs,control
R232	T280	T281	arg1Of	PBMCs,and
R233	T281	T278	arg2Of	and,in
R234	T283	T281	arg2Of	cells,and
R235	T283	T282	arg1Of	cells,THP-1
R236	T287	T271	arg1Of	alter,Finally
R237	T287	T272	arg1Of	alter,","
R238	T287	T284	arg2Of	alter,did
R239	T287	T285	arg1Of	alter,not
R240	T287	T286	arg1Of	alter,significantly
R241	T287	T292	arg1Of	alter,in
R242	T288	T289	arg1Of	IL-1β,or
R243	T290	T289	arg2Of	IL-8,or
R244	T291	T287	arg2Of	production,alter
R245	T291	T288	arg1Of	production,IL-1β
R246	T291	T290	arg1Of	production,IL-8
R247	T293	T292	arg2Of	response,in
R248	T293	T294	arg1Of	response,to
R249	T296	T294	arg2Of	aeruginosa,to
R250	T296	T295	arg1Of	aeruginosa,P.

Id	Subject	Object	Predicate	Lexical cue
T84	0-161	Sentence	denotes	Finally, chemical inhibition of CFTR activity in control PBMCs and THP-1 cells did not significantly alter IL-1β or IL-8 production in response to P. aeruginosa.
T14	0-161	Sentence	denotes	Finally, chemical inhibition of CFTR activity in control PBMCs and THP-1 cells did not significantly alter IL-1β or IL-8 production in response to P. aeruginosa.