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PMC:3333881 / 33670-33917
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15565 | 0-2 | TO | denotes | To |
T15566 | 3-11 | VB | denotes | validate |
T15567 | 12-15 | DT | denotes | the |
T15568 | 16-25 | VB | denotes | predicted |
T15569 | 26-31 | NN | denotes | NF-κB |
T15570 | 32-39 | NN | denotes | binding |
T15571 | 40-45 | NN | denotes | sites |
T15572 | 46-48 | IN | denotes | of |
T15573 | 49-52 | DT | denotes | the |
T15574 | 53-59 | NN | denotes | MIP-1α |
T15575 | 60-68 | NN | denotes | promoter |
T15576 | 68-69 | -COMMA- | denotes | , |
T15577 | 70-72 | PRP | denotes | we |
T15578 | 73-83 | VB | denotes | stimulated |
T15579 | 84-88 | NN | denotes | HeLa |
T15580 | 89-94 | NN | denotes | cells |
T15581 | 95-99 | IN | denotes | with |
T15582 | 100-105 | NN | denotes | TNF-α |
T15583 | 105-106 | -COMMA- | denotes | , |
T15584 | 107-108 | DT | denotes | a |
T15585 | 109-119 | JJ | denotes | well-known |
T15586 | 120-125 | NN | denotes | NF-κB |
T15587 | 126-133 | NN | denotes | inducer |
T15588 | 133-134 | -COMMA- | denotes | , |
T15589 | 135-138 | CC | denotes | and |
T15590 | 139-147 | VB | denotes | measured |
T15591 | 148-151 | DT | denotes | the |
T15592 | 152-162 | NN | denotes | expression |
T15593 | 163-169 | NN | denotes | levels |
T15594 | 170-172 | IN | denotes | of |
T15595 | 173-179 | NN | denotes | MIP-1α |
T15596 | 180-182 | IN | denotes | by |
T15597 | 183-192 | JJ | denotes | real-time |
T15598 | 193-196 | NN | denotes | PCR |
T15599 | 196-197 | -COMMA- | denotes | , |
T15600 | 198-201 | CC | denotes | and |
T15601 | 202-205 | DT | denotes | the |
T15602 | 206-209 | NN | denotes | p65 |
T15603 | 210-219 | NN | denotes | occupancy |
T15604 | 220-222 | IN | denotes | of |
T15605 | 223-226 | DT | denotes | the |
T15606 | 227-232 | NN | denotes | NF-κB |
T15607 | 233-238 | NN | denotes | sites |
T15608 | 239-241 | IN | denotes | by |
T15609 | 242-246 | NN | denotes | ChIP |
R12520 | T15566 | T15565 | arg1Of | validate,To |
R12521 | T15571 | T15566 | arg2Of | sites,validate |
R12522 | T15571 | T15567 | arg1Of | sites,the |
R12523 | T15571 | T15568 | arg2Of | sites,predicted |
R12524 | T15571 | T15569 | arg1Of | sites,NF-κB |
R12525 | T15571 | T15570 | arg1Of | sites,binding |
R12526 | T15571 | T15572 | arg1Of | sites,of |
R12527 | T15575 | T15572 | arg2Of | promoter,of |
R12528 | T15575 | T15573 | arg1Of | promoter,the |
R12529 | T15575 | T15574 | arg1Of | promoter,MIP-1α |
R12530 | T15577 | T15566 | arg1Of | we,validate |
R12531 | T15577 | T15578 | arg1Of | we,stimulated |
R12532 | T15577 | T15590 | arg1Of | we,measured |
R12533 | T15578 | T15581 | arg1Of | stimulated,with |
R12534 | T15578 | T15589 | arg1Of | stimulated,and |
R12535 | T15580 | T15578 | arg2Of | cells,stimulated |
R12536 | T15580 | T15579 | arg1Of | cells,HeLa |
R12537 | T15582 | T15581 | arg2Of | TNF-α,with |
R12538 | T15582 | T15583 | arg1Of | TNF-α,"," |
R12539 | T15587 | T15583 | arg2Of | inducer,"," |
R12540 | T15587 | T15584 | arg1Of | inducer,a |
R12541 | T15587 | T15585 | arg1Of | inducer,well-known |
R12542 | T15587 | T15586 | arg1Of | inducer,NF-κB |
R12543 | T15589 | T15565 | modOf | and,To |
R12544 | T15589 | T15576 | arg1Of | and,"," |
R12545 | T15589 | T15588 | arg1Of | and,"," |
R12546 | T15590 | T15589 | arg2Of | measured,and |
R12547 | T15593 | T15591 | arg1Of | levels,the |
R12548 | T15593 | T15592 | arg1Of | levels,expression |
R12549 | T15593 | T15594 | arg1Of | levels,of |
R12550 | T15593 | T15600 | arg1Of | levels,and |
R12551 | T15595 | T15594 | arg2Of | MIP-1α,of |
R12552 | T15595 | T15596 | arg1Of | MIP-1α,by |
R12553 | T15598 | T15596 | arg2Of | PCR,by |
R12554 | T15598 | T15597 | arg1Of | PCR,real-time |
R12555 | T15600 | T15590 | arg2Of | and,measured |
R12556 | T15600 | T15599 | arg1Of | and,"," |
R12557 | T15603 | T15600 | arg2Of | occupancy,and |
R12558 | T15603 | T15601 | arg1Of | occupancy,the |
R12559 | T15603 | T15602 | arg1Of | occupancy,p65 |
R12560 | T15603 | T15604 | arg1Of | occupancy,of |
R12561 | T15603 | T15608 | arg1Of | occupancy,by |
R12562 | T15607 | T15604 | arg2Of | sites,of |
R12563 | T15607 | T15605 | arg1Of | sites,the |
R12564 | T15607 | T15606 | arg1Of | sites,NF-κB |
R12565 | T15609 | T15608 | arg2Of | ChIP,by |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16349 | 0-2 | TO | denotes | To |
T16350 | 3-11 | VB | denotes | validate |
T16351 | 12-15 | DT | denotes | the |
T16352 | 16-25 | VBN | denotes | predicted |
T16353 | 26-31 | NN | denotes | NF-κB |
T16354 | 32-39 | JJ | denotes | binding |
T16355 | 40-45 | NNS | denotes | sites |
T16356 | 46-48 | IN | denotes | of |
T16357 | 49-52 | DT | denotes | the |
T16358 | 53-59 | JJ | denotes | MIP-1α |
T16359 | 60-68 | NN | denotes | promoter |
T16360 | 68-69 | , | denotes | , |
T16361 | 70-72 | PRP | denotes | we |
T16362 | 73-83 | VBD | denotes | stimulated |
T16363 | 84-88 | NNP | denotes | HeLa |
T16364 | 89-94 | NNS | denotes | cells |
T16365 | 95-99 | IN | denotes | with |
T16366 | 100-105 | NNP | denotes | TNF-α |
T16367 | 105-106 | , | denotes | , |
T16368 | 107-108 | DT | denotes | a |
T16369 | 109-119 | JJ | denotes | well-known |
T16370 | 120-125 | NN | denotes | NF-κB |
T16371 | 126-133 | NN | denotes | inducer |
T16372 | 133-134 | , | denotes | , |
T16373 | 135-138 | CC | denotes | and |
T16374 | 139-147 | VBD | denotes | measured |
T16375 | 148-151 | DT | denotes | the |
T16376 | 152-162 | NN | denotes | expression |
T16377 | 163-169 | NNS | denotes | levels |
T16378 | 170-172 | IN | denotes | of |
T16379 | 173-179 | NN | denotes | MIP-1α |
T16380 | 180-182 | IN | denotes | by |
T16381 | 183-192 | JJ | denotes | real-time |
T16382 | 193-196 | NNP | denotes | PCR |
T16383 | 196-197 | , | denotes | , |
T16384 | 198-201 | CC | denotes | and |
T16385 | 202-205 | DT | denotes | the |
T16386 | 206-209 | NNS | denotes | p65 |
T16387 | 210-219 | NN | denotes | occupancy |
T16388 | 220-222 | IN | denotes | of |
T16389 | 223-226 | DT | denotes | the |
T16390 | 227-232 | NNP | denotes | NF-κB |
T16391 | 233-238 | NNS | denotes | sites |
T16392 | 239-241 | IN | denotes | by |
T16393 | 242-246 | NNP | denotes | ChIP |
T16394 | 246-247 | . | denotes | . |
R13139 | T16349 | T16350 | aux | To,validate |
R13140 | T16350 | T16362 | advcl | validate,stimulated |
R13141 | T16351 | T16355 | det | the,sites |
R13142 | T16352 | T16355 | amod | predicted,sites |
R13143 | T16353 | T16355 | amod | NF-κB,sites |
R13144 | T16354 | T16355 | amod | binding,sites |
R13145 | T16355 | T16350 | dobj | sites,validate |
R13146 | T16356 | T16355 | prep | of,sites |
R13147 | T16357 | T16359 | det | the,promoter |
R13148 | T16358 | T16359 | amod | MIP-1α,promoter |
R13149 | T16359 | T16356 | pobj | promoter,of |
R13150 | T16360 | T16362 | punct | ",",stimulated |
R13151 | T16361 | T16362 | nsubj | we,stimulated |
R13152 | T16362 | T16362 | ROOT | stimulated,stimulated |
R13153 | T16363 | T16364 | compound | HeLa,cells |
R13154 | T16364 | T16362 | dobj | cells,stimulated |
R13155 | T16365 | T16362 | prep | with,stimulated |
R13156 | T16366 | T16365 | pobj | TNF-α,with |
R13157 | T16367 | T16366 | punct | ",",TNF-α |
R13158 | T16368 | T16371 | det | a,inducer |
R13159 | T16369 | T16371 | amod | well-known,inducer |
R13160 | T16370 | T16371 | compound | NF-κB,inducer |
R13161 | T16371 | T16366 | appos | inducer,TNF-α |
R13162 | T16372 | T16362 | punct | ",",stimulated |
R13163 | T16373 | T16362 | cc | and,stimulated |
R13164 | T16374 | T16362 | conj | measured,stimulated |
R13165 | T16375 | T16377 | det | the,levels |
R13166 | T16376 | T16377 | compound | expression,levels |
R13167 | T16377 | T16374 | dobj | levels,measured |
R13168 | T16378 | T16377 | prep | of,levels |
R13169 | T16379 | T16378 | pobj | MIP-1α,of |
R13170 | T16380 | T16374 | prep | by,measured |
R13171 | T16381 | T16382 | amod | real-time,PCR |
R13172 | T16382 | T16380 | pobj | PCR,by |
R13173 | T16383 | T16374 | punct | ",",measured |
R13174 | T16384 | T16374 | cc | and,measured |
R13175 | T16385 | T16387 | det | the,occupancy |
R13176 | T16386 | T16387 | amod | p65,occupancy |
R13177 | T16387 | T16374 | conj | occupancy,measured |
R13178 | T16388 | T16387 | prep | of,occupancy |
R13179 | T16389 | T16391 | det | the,sites |
R13180 | T16390 | T16391 | compound | NF-κB,sites |
R13181 | T16391 | T16388 | pobj | sites,of |
R13182 | T16392 | T16387 | prep | by,occupancy |
R13183 | T16393 | T16392 | pobj | ChIP,by |
R13184 | T16394 | T16362 | punct | .,stimulated |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16621 | 26-39 | http://purl.obolibrary.org/obo/GO_0051059 | denotes | NF-κB binding |
T16622 | 32-39 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16628 | 89-94 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15230 | 0-247 | Sentence | denotes | To validate the predicted NF-κB binding sites of the MIP-1α promoter, we stimulated HeLa cells with TNF-α, a well-known NF-κB inducer, and measured the expression levels of MIP-1α by real-time PCR, and the p65 occupancy of the NF-κB sites by ChIP. |
T202 | 0-247 | Sentence | denotes | To validate the predicted NF-κB binding sites of the MIP-1α promoter, we stimulated HeLa cells with TNF-α, a well-known NF-κB inducer, and measured the expression levels of MIP-1α by real-time PCR, and the p65 occupancy of the NF-κB sites by ChIP. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Speculation |
---|---|---|---|---|---|
T17329 | 53-59 | Protein | denotes | MIP-1α | |
T17330 | 100-105 | Protein | denotes | TNF-α | |
T17331 | 152-162 | Gene_expression | denotes | expression | true |
T17332 | 173-179 | Protein | denotes | MIP-1α | |
T17333 | 206-209 | Protein | denotes | p65 | |
T17334 | 210-219 | Binding | denotes | occupancy | true |
T17335 | 227-238 | Entity | denotes | NF-κB sites | |
R13938 | T17332 | T17331 | themeOf | MIP-1α,expression | |
R13939 | T17333 | T17334 | themeOf | p65,occupancy | |
R13940 | T17335 | T17334 | themeOf | NF-κB sites,occupancy | |
R13941 | T17335 | T17332 | partOf | NF-κB sites,MIP-1α |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T17475 | 26-31 | Protein | denotes | NF-κB |
T17476 | 53-68 | Protein | denotes | MIP-1α promoter |
T17477 | 100-105 | Protein | denotes | TNF-α |
T17478 | 120-125 | Protein | denotes | NF-κB |
T17479 | 173-179 | Protein | denotes | MIP-1α |
T17480 | 206-209 | Protein | denotes | p65 |
T17481 | 227-238 | Protein | denotes | NF-κB sites |
T17482 | 126-133 | Positive_regulation | denotes | inducer |
T17483 | 152-162 | Gene_expression | denotes | expression |
T17484 | 210-219 | Positive_regulation | denotes | occupancy |
T17485 | 210-219 | Positive_regulation | denotes | occupancy |
R14045 | T17478 | T17482 | themeOf | NF-κB,inducer |
R14046 | T17479 | T17483 | themeOf | MIP-1α,expression |
R14047 | T17480 | T17484 | themeOf | p65,occupancy |
R14048 | T17481 | T17485 | themeOf | NF-κB sites,occupancy |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T15011 | 53-59 | Protein | denotes | MIP-1α | |
T15012 | 100-105 | Protein | denotes | TNF-α | |
T15013 | 152-162 | Gene_expression | denotes | expression | |
T15014 | 173-179 | Protein | denotes | MIP-1α | true |
T15015 | 206-209 | Protein | denotes | p65 | true |
T15016 | 210-219 | Binding | denotes | occupancy | true |
T15017 | 227-238 | Entity | denotes | NF-κB sites | |
R12024 | T15014 | T15013 | themeOf | MIP-1α,expression | |
R12025 | T15015 | T15016 | themeOf | p65,occupancy | |
R12026 | T15017 | T15015 | partOf | NF-κB sites,p65 | |
R12027 | T15017 | T15014 | partOf | NF-κB sites,MIP-1α | |
R12028 | T15017 | T15013 | themeOf | NF-κB sites,expression | |
R12029 | T15017 | T15016 | themeOf | NF-κB sites,occupancy |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Speculation |
---|---|---|---|---|---|
T15146 | 53-59 | Protein | denotes | MIP-1α | |
T15147 | 100-105 | Protein | denotes | TNF-α | |
T15148 | 152-162 | Gene_expression | denotes | expression | true |
T15149 | 173-179 | Protein | denotes | MIP-1α | |
T15150 | 206-209 | Protein | denotes | p65 | |
T15151 | 210-219 | Binding | denotes | occupancy | true |
T15152 | 227-238 | Entity | denotes | NF-κB sites | |
R12121 | T15149 | T15148 | themeOf | MIP-1α,expression | |
R12122 | T15150 | T15151 | themeOf | p65,occupancy | |
R12123 | T15152 | T15151 | themeOf | NF-κB sites,occupancy | |
R12124 | T15152 | T15149 | partOf | NF-κB sites,MIP-1α |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15915 | 53-59 | P10147 | denotes | MIP-1α |
T15916 | 100-103 | P01375 | denotes | TNF |
T15917 | 100-105 | P01375 | denotes | TNF-α |
T15918 | 173-179 | P10147 | denotes | MIP-1α |
T15919 | 206-209 | Q04206 | denotes | p65 |
T15920 | 206-209 | P21579 | denotes | p65 |