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test3

Id Subject Object Predicate Lexical cue
T11692 2262-2272 Negative_regulation denotes deficiency
T11691 2163-2168 Protein denotes RIG-I
T11690 2108-2118 Gene_expression denotes expression
T11689 1870-1875 Protein denotes IRF-3
T11688 1841-1846 Protein denotes RIG-I
T11687 1832-1840 Regulation denotes regulate
T11686 1753-1757 Protein denotes CYLD
T11685 1556-1566 Positive_regulation denotes activation
T11684 1551-1555 Protein denotes IRF3
T11683 1416-1426 Negative_regulation denotes deficiency
T11682 1341-1345 Protein denotes IKKε
T11681 1332-1336 Protein denotes TBK1
T11680 1314-1328 Binding denotes ubiquitination
T11679 1225-1230 Protein denotes RIG-I
T11678 1147-1151 Protein denotes IRF3
T11677 1111-1115 Protein denotes IKKε
T11676 1102-1106 Protein denotes TBK1
T11675 1066-1075 Regulation denotes affecting
T11674 1010-1017 Negative_regulation denotes disrupt
T11673 998-1003 Protein denotes ABIN1
T11672 969-976 Binding denotes binding
T11671 787-791 Protein denotes IRF3
T11670 539-549 Positive_regulation denotes activation
T11669 534-538 Protein denotes IRF3
T11668 493-497 Protein denotes IFNβ
T11667 482-487 Protein denotes MIP-2
T11666 478-480 Protein denotes KC
T11665 472-476 Protein denotes IL-6
T11664 467-470 Protein denotes TNF
T11663 345-350 Protein denotes RIG-I
T11662 146-151 Protein denotes RIG-I
T11661 90-95 Protein denotes RIG-I
T11660 64-74 Positive_regulation denotes activation
T11659 59-63 Protein denotes IRF3
T11658 40-48 Positive_regulation denotes enhanced
T11657 17-26 Negative_regulation denotes deficient
T11643 2163-2168 Protein denotes RIG-I
T11642 1870-1875 Protein denotes IRF-3
T11641 1841-1846 Protein denotes RIG-I
T11640 1753-1757 Protein denotes CYLD
T11639 1551-1555 Protein denotes IRF3
T11638 1341-1345 Protein denotes IKKε
T11637 1332-1336 Protein denotes TBK1
T11636 1225-1230 Protein denotes RIG-I
T11635 1147-1151 Protein denotes IRF3
T11634 1111-1115 Protein denotes IKKε
T11633 1102-1106 Protein denotes TBK1
T11632 998-1003 Protein denotes ABIN1
T11631 787-791 Protein denotes IRF3
T11630 534-538 Protein denotes IRF3
T11629 493-497 Protein denotes IFNβ
T11628 482-487 Protein denotes MIP-2
T11627 478-480 Protein denotes KC
T11626 472-476 Protein denotes IL-6
T11625 467-470 Protein denotes TNF
T11624 345-350 Protein denotes RIG-I
T11623 146-151 Protein denotes RIG-I
T11622 90-95 Protein denotes RIG-I
T11621 59-63 Protein denotes IRF3
R8472 T11657 T11658 causeOf deficient,enhanced
R8473 T11659 T11660 themeOf IRF3,activation
R8474 T11660 T11658 themeOf activation,enhanced
R8475 T11669 T11670 themeOf IRF3,activation
R8476 T11673 T11672 themeOf ABIN1,binding
R8477 T11681 T11680 themeOf TBK1,ubiquitination
R8478 T11682 T11680 themeOf IKKε,ubiquitination
R8479 T11684 T11685 themeOf IRF3,activation
R8480 T11689 T11687 themeOf IRF-3,regulate

2_test

Id Subject Object Predicate Lexical cue
22396652-17942531-98461879 235-237 17942531 denotes 13
22396652-20599425-98461880 886-888 20599425 denotes 80
22396652-20304918-98461881 1153-1155 20304918 denotes 81
22396652-21885437-98461882 1159-1161 21885437 denotes 82
22396652-17991829-98461883 1748-1750 17991829 denotes 28
22396652-18467330-98461884 1759-1761 18467330 denotes 29
22396652-18636086-98461885 1765-1767 18636086 denotes 30
22396652-19996094-98461886 1779-1781 19996094 denotes 31
22396652-16765340-98461887 1793-1795 16765340 denotes 49
22396652-15661910-98461888 1798-1800 15661910 denotes 52

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T12900 2454-2466 VB denotes investigated
T12899 2451-2453 VB denotes be
T12898 2448-2450 TO denotes to
T12897 2440-2447 VB denotes remains
T12896 2438-2439 -COMMA- denotes ,
T12895 2433-2438 NN denotes cells
T12894 2422-2432 JJ denotes epithelial
T12893 2417-2421 NN denotes lung
T12892 2414-2416 IN denotes as
T12891 2409-2413 JJ denotes such
T12890 2407-2408 -COMMA- denotes ,
T12889 2404-2407 NN denotes IAV
T12888 2401-2403 TO denotes to
T12887 2392-2400 NN denotes response
T12886 2388-2391 DT denotes the
T12885 2385-2387 IN denotes in
T12884 2374-2384 VB denotes implicated
T12883 2370-2373 VB denotes are
T12882 2365-2369 WDT denotes that
T12881 2359-2364 NN denotes types
T12880 2354-2358 NN denotes cell
T12879 2348-2353 JJ denotes other
T12878 2345-2347 IN denotes in
T12877 2340-2344 NN denotes role
T12876 2326-2339 JJ denotes non-redundant
T12875 2318-2325 JJ denotes similar
T12874 2316-2317 DT denotes a
T12873 2312-2315 VB denotes has
T12872 2308-2311 NN denotes A20
T12871 2305-2307 IN denotes If
T12870 2293-2303 NN denotes conditions
T12869 2279-2292 JJ denotes physiological
T12868 2273-2278 IN denotes under
T12867 2262-2272 NN denotes deficiency
T12866 2258-2261 NN denotes A20
T12865 2254-2257 IN denotes for
T12864 2243-2253 VB denotes substitute
T12863 2239-2242 RB denotes not
T12862 2236-2239 MD denotes can
T12861 2231-2235 NN denotes DUBs
T12860 2225-2230 JJ denotes other
T12859 2220-2224 IN denotes that
T12858 2216-2219 CC denotes and
T12857 2206-2215 NN denotes infection
T12856 2202-2205 NN denotes IAV
T12855 2199-2201 TO denotes to
T12854 2190-2198 NN denotes response
T12853 2187-2189 IN denotes in
T12852 2177-2186 NN denotes signaling
T12851 2169-2176 VB denotes induced
T12850 2163-2168 NN denotes RIG-I
T12849 2160-2162 IN denotes of
T12848 2149-2159 NN denotes gatekeeper
T12847 2141-2148 JJ denotes central
T12846 2139-2140 DT denotes a
T12845 2136-2138 VB denotes is
T12844 2130-2135 NN denotes cells
T12843 2122-2129 JJ denotes myeloid
T12842 2119-2121 IN denotes in
T12841 2108-2118 NN denotes expression
T12840 2104-2107 NN denotes A20
T12839 2099-2103 IN denotes that
T12838 2089-2098 VB denotes indicates
T12837 2080-2088 VB denotes describe
T12836 2075-2079 RB denotes here
T12835 2072-2074 PRP denotes we
T12834 2067-2071 IN denotes that
T12833 2062-2066 NN denotes mice
T12832 2051-2061 NN denotes A20myel-KO
T12831 2048-2050 IN denotes of
T12830 2038-2047 NN denotes phenotype
T12829 2027-2037 JJ denotes protective
T12828 2021-2026 JJ denotes clear
T12827 2017-2020 DT denotes The
T12826 2005-2015 NN denotes conditions
T12825 1987-2004 JJ denotes non-physiological
T12824 1981-1986 IN denotes under
T12823 1972-1980 VB denotes obtained
T12822 1968-1971 VB denotes was
T12821 1964-1967 CC denotes and
T12820 1959-1963 NN denotes data
T12819 1953-1958 FW denotes vitro
T12818 1950-1952 FW denotes in
T12817 1947-1949 TO denotes to
T12816 1939-1946 VB denotes limited
T12815 1935-1938 VB denotes was
T12814 1931-1934 RB denotes far
T12813 1928-1930 RB denotes so
T12812 1919-1927 NN denotes evidence
T12811 1917-1918 -COMMA- denotes ,
T12810 1910-1917 RB denotes However
T12809 1898-1908 NN denotes redundancy
T12808 1889-1897 JJ denotes possible
T12807 1877-1888 VB denotes implicating
T12806 1875-1876 -COMMA- denotes ,
T12805 1870-1875 NN denotes IRF-3
T12804 1866-1869 CC denotes and
T12803 1860-1865 NN denotes NF-κB
T12802 1857-1859 TO denotes to
T12801 1847-1856 NN denotes signaling
T12800 1841-1846 NN denotes RIG-I
T12799 1832-1840 VB denotes regulate
T12798 1821-1831 RB denotes negatively
T12797 1818-1820 TO denotes to
T12796 1812-1817 VB denotes shown
T12795 1807-1811 VB denotes been
T12794 1802-1806 VB denotes have
T12793 1800-1801 -RRB- denotes ]
T12792 1798-1800 CD denotes 52
T12791 1797-1798 -LRB- denotes [
T12790 1796-1797 CD denotes –
T12789 1795-1796 -RRB- denotes ]
T12788 1793-1795 CD denotes 49
T12787 1792-1793 -LRB- denotes [
T12786 1788-1791 NN denotes A20
T12785 1784-1787 CC denotes and
T12784 1782-1783 -COMMA- denotes ,
T12783 1781-1782 -RRB- denotes ]
T12782 1779-1781 CD denotes 31
T12781 1778-1779 -LRB- denotes [
T12780 1770-1777 CD denotes OTUB1/2
T12779 1768-1769 -COMMA- denotes ,
T12778 1767-1768 -RRB- denotes ]
T12777 1765-1767 CD denotes 30
T12776 1764-1765 -LRB- denotes [
T12775 1762-1763 -COMMA- denotes ,
T12774 1761-1762 -RRB- denotes ]
T12773 1759-1761 CD denotes 29
T12772 1758-1759 -LRB- denotes [
T12771 1753-1757 NN denotes CYLD
T12770 1751-1752 -COMMA- denotes ,
T12769 1750-1751 -RRB- denotes ]
T12768 1748-1750 CD denotes 28
T12767 1747-1748 -LRB- denotes [
T12766 1742-1746 NNP denotes DUBA
T12765 1739-1741 IN denotes as
T12764 1734-1738 JJ denotes such
T12763 1732-1733 -COMMA- denotes ,
T12762 1731-1732 -RRB- denotes )
T12761 1727-1731 NN denotes DUBs
T12760 1726-1727 -LRB- denotes (
T12759 1718-1725 NN denotes enzymes
T12758 1701-1717 VB denotes deubiquitinating
T12757 1695-1700 JJ denotes other
T12756 1686-1694 JJ denotes Multiple
T12755 1674-1684 NN denotes laboratory
T12754 1670-1673 PRP-DOLLAR- denotes our
T12753 1667-1669 IN denotes in
T12752 1652-1666 NN denotes investigations
T12751 1645-1651 JJ denotes future
T12750 1642-1644 IN denotes of
T12749 1636-1641 NN denotes topic
T12748 1632-1635 DT denotes the
T12747 1629-1631 VB denotes be
T12746 1624-1628 MD denotes will
T12745 1613-1623 NN denotes substrates
T12744 1607-1612 DT denotes these
T12743 1604-1606 IN denotes of
T12742 1589-1603 NN denotes identification
T12741 1585-1588 DT denotes The
T12740 1578-1583 NN denotes cells
T12739 1570-1577 JJ denotes myeloid
T12738 1567-1569 IN denotes in
T12737 1556-1566 NN denotes activation
T12736 1551-1555 NN denotes IRF3
T12735 1547-1550 CC denotes and
T12734 1541-1546 NN denotes NF-κB
T12733 1533-1540 VB denotes mediate
T12732 1528-1532 WDT denotes that
T12731 1517-1527 NN denotes substrates
T12730 1511-1516 JJ denotes other
T12629 899-906 NN denotes context
T12628 894-898 DT denotes this
T12627 891-893 IN denotes In
T12626 888-889 -RRB- denotes ]
T12625 886-888 CD denotes 80
T12624 885-886 -LRB- denotes [
T12623 876-884 NN denotes proteins
T12622 866-875 NN denotes signaling
T12621 856-865 JJ denotes different
T12620 853-855 IN denotes of
T12619 846-852 NN denotes status
T12618 831-845 NN denotes ubiquitination
T12617 827-830 DT denotes the
T12616 816-826 VB denotes modulating
T12615 813-815 IN denotes by
T12614 803-812 NN denotes functions
T12613 792-802 JJ denotes inhibitory
T12612 787-791 NN denotes IRF3
T12611 783-786 CC denotes and
T12610 777-782 NN denotes NF-κB
T12609 773-776 PRP-DOLLAR- denotes its
T12608 767-772 VB denotes exert
T12607 764-766 TO denotes to
T12606 755-763 VB denotes believed
T12605 752-754 VB denotes is
T12604 748-751 NN denotes A20
T12603 736-746 NN denotes expression
T12602 731-735 NN denotes gene
T12601 715-730 JJ denotes proinflammatory
T12600 712-714 TO denotes to
T12599 701-711 VB denotes contribute
T12598 697-700 MD denotes may
T12597 692-696 WDT denotes that
T12596 683-691 NN denotes pathways
T12595 673-682 NN denotes signaling
T12594 667-672 JJ denotes other
T12593 664-666 IN denotes on
T12592 660-663 NN denotes A20
T12591 657-659 IN denotes of
T12590 650-656 NN denotes effect
T12589 639-649 JJ denotes additional
T12588 636-638 DT denotes an
T12587 628-635 VB denotes exclude
T12586 624-627 RB denotes not
T12585 619-623 VB denotes does
T12584 614-618 DT denotes this
T12583 612-613 -COMMA- denotes ,
T12582 605-612 RB denotes However
T12581 598-603 NN denotes genes
T12580 592-597 DT denotes these
T12579 580-591 VB denotes controlling
T12578 571-579 NN denotes pathways
T12577 565-570 JJ denotes major
T12576 561-564 DT denotes the
T12575 557-560 VB denotes are
T12574 551-556 WDT denotes which
T12573 549-550 -COMMA- denotes ,
T12572 539-549 NN denotes activation
T12571 534-538 NN denotes IRF3
T12570 530-533 CC denotes and
T12569 524-529 NN denotes NF-κB
T12568 513-523 VB denotes regulating
T12567 502-512 RB denotes negatively
T12566 499-501 IN denotes by
T12565 497-498 -RRB- denotes )
T12564 493-497 NN denotes IFNβ
T12563 489-492 CC denotes and
T12562 487-488 -COMMA- denotes ,
T12561 482-487 NN denotes MIP-2
T12560 480-481 -COMMA- denotes ,
T12559 478-480 NN denotes KC
T12558 476-477 -COMMA- denotes ,
T12557 472-476 NN denotes IL-6
T12556 470-471 -COMMA- denotes ,
T12555 467-470 NN denotes TNF
T12554 463-466 IN denotes for
T12553 452-462 NN denotes manuscript
T12552 448-451 PRP-DOLLAR- denotes our
T12551 445-447 IN denotes in
T12550 439-444 VB denotes shown
T12549 436-438 IN denotes as
T12548 435-436 -LRB- denotes (
T12547 424-434 NN denotes expression
T12546 419-423 NN denotes gene
T12545 403-418 JJ denotes proinflammatory
T12544 391-402 JJ denotes IAV-induced
T12543 382-390 VB denotes inhibits
T12542 378-381 NN denotes A20
T12541 373-377 IN denotes that
T12540 365-372 VB denotes propose
T12539 362-364 PRP denotes We
T12538 351-360 NN denotes signaling
T12537 345-350 NN denotes RIG-I
T12536 336-344 VB denotes enhanced
T12535 327-335 VB denotes reflects
T12534 317-326 NN denotes infection
T12533 312-316 NN denotes lung
T12532 308-311 NN denotes IAV
T12531 305-307 TO denotes to
T12530 300-304 NN denotes mice
T12529 289-299 NN denotes A20myel-KO
T12528 286-288 IN denotes of
T12527 277-285 NN denotes response
T12526 270-276 JJ denotes immune
T12525 260-269 VB denotes increased
T12524 256-259 DT denotes the
T12523 251-255 IN denotes that
T12522 240-250 VB denotes suggesting
T12521 238-239 -COMMA- denotes ,
T12520 237-238 -RRB- denotes ]
T12519 235-237 CD denotes 13
T12518 234-235 -LRB- denotes [
T12517 230-233 NN denotes IAV
T12516 227-229 TO denotes to
T12515 218-226 NN denotes response
T12514 211-217 JJ denotes immune
T12513 204-210 JJ denotes innate
T12512 200-203 DT denotes the
T12511 197-199 IN denotes in
T12510 192-196 NN denotes role
T12509 188-191 JJ denotes key
T12508 186-187 DT denotes a
T12507 181-185 VB denotes play
T12506 178-180 TO denotes to
T12505 172-177 VB denotes shown
T12504 167-171 VB denotes been
T12503 156-166 RB denotes previously
T12502 152-155 VB denotes has
T12501 146-151 NN denotes RIG-I
T12500 141-144 NN denotes RNA
T12499 132-140 JJ denotes stranded
T12498 125-131 JJ denotes double
T12497 121-124 NN denotes LMW
T12496 111-120 JJ denotes synthetic
T12495 108-110 IN denotes by
T12494 96-107 NN denotes stimulation
T12493 90-95 NN denotes RIG-I
T12492 87-89 TO denotes to
T12491 78-86 NN denotes response
T12490 75-77 IN denotes in
T12489 64-74 NN denotes activation
T12488 59-63 NN denotes IRF3
T12487 55-58 CC denotes and
T12486 49-54 NN denotes NF-κB
T12485 40-48 VB denotes enhanced
T12484 32-39 NN denotes display
T12483 27-31 NN denotes BMDM
T12482 17-26 JJ denotes deficient
T12481 13-16 NN denotes A20
T12480 8-12 IN denotes that
T12479 3-7 VB denotes show
T12478 0-2 PRP denotes We
T12729 1503-1510 VB denotes targets
T12728 1498-1502 RB denotes also
T12727 1494-1497 NN denotes A20
T12726 1489-1493 IN denotes that
T12725 1481-1488 RB denotes however
T12724 1472-1480 VB denotes excluded
T12723 1469-1471 VB denotes be
T12722 1465-1468 RB denotes not
T12721 1462-1465 MD denotes can
T12720 1459-1461 PRP denotes It
T12719 1451-1457 NN denotes status
T12718 1436-1450 NN denotes ubiquitination
T12717 1430-1435 PRP-DOLLAR- denotes their
T12716 1427-1429 IN denotes on
T12715 1416-1426 NN denotes deficiency
T12714 1412-1415 NN denotes A20
T12713 1409-1411 IN denotes of
T12712 1402-1408 NN denotes effect
T12711 1398-1401 DT denotes the
T12710 1389-1397 VB denotes studying
T12709 1384-1388 IN denotes from
T12708 1381-1383 PRP denotes us
T12707 1370-1380 VB denotes preventing
T12706 1368-1369 -COMMA- denotes ,
T12705 1357-1368 NN denotes macrophages
T12704 1349-1356 JJ denotes primary
T12703 1346-1348 IN denotes in
T12702 1341-1345 NN denotes IKKε
T12701 1337-1340 CC denotes and
T12700 1332-1336 NN denotes TBK1
T12699 1329-1331 IN denotes of
T12698 1314-1328 NN denotes ubiquitination
T12697 1307-1313 VB denotes detect
T12696 1299-1306 RB denotes clearly
T12695 1296-1298 TO denotes to
T12694 1289-1295 JJ denotes unable
T12693 1284-1288 VB denotes were
T12692 1281-1283 PRP denotes we
T12691 1277-1280 RB denotes far
T12690 1274-1276 RB denotes So
T12689 1265-1272 JJ denotes unclear
T12688 1259-1264 RB denotes still
T12687 1256-1258 VB denotes is
T12686 1245-1255 NN denotes activation
T12685 1239-1244 NN denotes NF-κB
T12684 1231-1238 VB denotes induced
T12683 1225-1230 NN denotes RIG-I
T12682 1222-1224 IN denotes of
T12681 1211-1221 NN denotes regulation
T12680 1207-1210 DT denotes the
T12679 1204-1206 IN denotes in
T12678 1195-1203 VB denotes involved
T12677 1191-1194 VB denotes are
T12676 1180-1190 NN denotes mechanisms
T12675 1172-1179 JJ denotes similar
T12674 1164-1171 IN denotes Whether
T12673 1161-1162 -RRB- denotes ]
T12672 1159-1161 CD denotes 82
T12671 1158-1159 -LRB- denotes [
T12670 1156-1157 -COMMA- denotes ,
T12669 1155-1156 -RRB- denotes ]
T12668 1153-1155 CD denotes 81
T12667 1152-1153 -LRB- denotes [
T12666 1147-1151 NN denotes IRF3
T12665 1138-1146 NN denotes activity
T12664 1135-1137 TO denotes to
T12663 1127-1134 NN denotes ability
T12662 1121-1126 PRP-DOLLAR- denotes their
T12661 1117-1120 CC denotes and
T12660 1115-1116 -COMMA- denotes ,
T12659 1111-1115 NN denotes IKKε
T12658 1107-1110 CC denotes and
T12657 1102-1106 NN denotes TBK1
T12656 1099-1101 IN denotes of
T12655 1076-1098 NN denotes K63-polyubiquitination
T12654 1066-1075 VB denotes affecting
T12653 1055-1065 RB denotes negatively
T12652 1047-1054 RB denotes thereby
T12651 1045-1046 -COMMA- denotes ,
T12650 1038-1045 NN denotes complex
T12649 1022-1037 NN denotes TRAF3-TBK1-IKKε
T12648 1018-1021 DT denotes the
T12647 1010-1017 VB denotes disrupt
T12646 1007-1009 TO denotes to
T12645 1004-1006 TO denotes to
T12644 998-1003 NN denotes ABIN1
T12643 994-997 CC denotes and
T12642 986-993 NN denotes TAX1BP1
T12641 977-985 NN denotes proteins
T12640 959-976 JJ denotes ubiquitin-binding
T12639 955-958 DT denotes the
T12638 950-954 IN denotes with
T12637 939-949 VB denotes cooperates
T12636 935-938 NN denotes A20
T12635 930-934 IN denotes that
T12634 924-929 VB denotes shown
T12633 915-923 RB denotes recently
T12632 911-914 VB denotes was
T12631 908-910 PRP denotes it
T12630 906-907 -COMMA- denotes ,
R9019 T12478 T12479 arg1Of We,show
R9020 T12484 T12481 arg1Of display,A20
R9021 T12484 T12482 arg1Of display,deficient
R9022 T12484 T12483 arg1Of display,BMDM
R9023 T12484 T12485 arg1Of display,enhanced
R9024 T12485 T12479 arg2Of enhanced,show
R9025 T12485 T12480 arg1Of enhanced,that
R9026 T12486 T12487 arg1Of NF-κB,and
R9027 T12488 T12487 arg2Of IRF3,and
R9028 T12489 T12485 arg2Of activation,enhanced
R9029 T12489 T12486 arg1Of activation,NF-κB
R9030 T12489 T12488 arg1Of activation,IRF3
R9031 T12489 T12490 arg1Of activation,in
R9032 T12489 T12495 arg1Of activation,by
R9033 T12490 T12492 arg1Of in,to
R9034 T12491 T12490 arg2Of response,in
R9035 T12494 T12490 arg3Of stimulation,in
R9036 T12494 T12493 arg1Of stimulation,RIG-I
R9037 T12498 T12496 arg1Of double,synthetic
R9038 T12498 T12497 arg1Of double,LMW
R9039 T12500 T12495 arg2Of RNA,by
R9040 T12500 T12498 arg1Of RNA,double
R9041 T12500 T12499 arg1Of RNA,stranded
R9042 T12501 T12502 arg1Of RIG-I,has
R9043 T12501 T12504 arg1Of RIG-I,been
R9044 T12501 T12505 arg2Of RIG-I,shown
R9045 T12501 T12507 arg1Of RIG-I,play
R9046 T12505 T12502 arg2Of shown,has
R9047 T12505 T12503 arg1Of shown,previously
R9048 T12505 T12504 arg2Of shown,been
R9049 T12507 T12505 arg3Of play,shown
R9050 T12507 T12506 arg1Of play,to
R9051 T12507 T12511 arg1Of play,in
R9052 T12507 T12521 arg1Of play,","
R9053 T12507 T12522 modOf play,suggesting
R9054 T12510 T12507 arg2Of role,play
R9055 T12510 T12508 arg1Of role,a
R9056 T12510 T12509 arg1Of role,key
R9057 T12515 T12511 arg2Of response,in
R9058 T12515 T12512 arg1Of response,the
R9059 T12515 T12513 arg1Of response,innate
R9060 T12515 T12514 arg1Of response,immune
R9061 T12515 T12516 arg1Of response,to
R9062 T12517 T12516 arg2Of IAV,to
R9063 T12517 T12518 arg1Of IAV,[
R9064 T12519 T12518 arg2Of 13,[
R9065 T12520 T12518 arg3Of ],[
R9066 T12527 T12524 arg1Of response,the
R9067 T12527 T12525 arg2Of response,increased
R9068 T12527 T12526 arg1Of response,immune
R9069 T12527 T12528 arg1Of response,of
R9070 T12527 T12531 arg1Of response,to
R9071 T12527 T12535 arg1Of response,reflects
R9072 T12530 T12528 arg2Of mice,of
R9073 T12530 T12529 arg1Of mice,A20myel-KO
R9074 T12534 T12531 arg2Of infection,to
R9075 T12534 T12532 arg1Of infection,IAV
R9076 T12534 T12533 arg1Of infection,lung
R9077 T12535 T12522 arg2Of reflects,suggesting
R9078 T12535 T12523 arg1Of reflects,that
R9079 T12538 T12535 arg2Of signaling,reflects
R9080 T12538 T12536 arg2Of signaling,enhanced
R9081 T12538 T12537 arg1Of signaling,RIG-I
R9082 T12539 T12540 arg1Of We,propose
R9083 T12542 T12543 arg1Of A20,inhibits
R9084 T12543 T12540 arg2Of inhibits,propose
R9085 T12543 T12541 arg1Of inhibits,that
R9086 T12543 T12548 arg1Of inhibits,(
R9087 T12543 T12566 arg1Of inhibits,by
R9088 T12547 T12543 arg2Of expression,inhibits
R9089 T12547 T12544 arg1Of expression,IAV-induced
R9090 T12547 T12545 arg1Of expression,proinflammatory
R9091 T12547 T12546 arg1Of expression,gene
R9092 T12549 T12548 arg2Of as,(
R9093 T12550 T12549 arg2Of shown,as
R9094 T12550 T12551 arg1Of shown,in
R9095 T12553 T12551 arg2Of manuscript,in
R9096 T12553 T12552 arg1Of manuscript,our
R9097 T12553 T12554 arg1Of manuscript,for
R9098 T12555 T12556 arg1Of TNF,","
R9099 T12556 T12558 arg1Of ",",","
R9100 T12557 T12556 arg2Of IL-6,","
R9101 T12558 T12560 arg1Of ",",","
R9102 T12559 T12558 arg2Of KC,","
R9103 T12560 T12563 arg1Of ",",and
R9104 T12561 T12560 arg2Of MIP-2,","
R9105 T12563 T12554 arg2Of and,for
R9106 T12563 T12562 arg1Of and,","
R9107 T12564 T12563 arg2Of IFNβ,and
R9108 T12565 T12548 arg3Of ),(
R9109 T12568 T12566 arg2Of regulating,by
R9110 T12568 T12567 arg1Of regulating,negatively
R9111 T12569 T12570 arg1Of NF-κB,and
R9112 T12571 T12570 arg2Of IRF3,and
R9113 T12572 T12568 arg2Of activation,regulating
R9114 T12572 T12569 arg1Of activation,NF-κB
R9115 T12572 T12571 arg1Of activation,IRF3
R9116 T12572 T12573 arg1Of activation,","
R9117 T12572 T12574 arg1Of activation,which
R9118 T12572 T12575 arg1Of activation,are
R9119 T12578 T12575 arg2Of pathways,are
R9120 T12578 T12576 arg1Of pathways,the
R9121 T12578 T12577 arg1Of pathways,major
R9122 T12578 T12579 arg1Of pathways,controlling
R9123 T12581 T12579 arg2Of genes,controlling
R9124 T12581 T12580 arg1Of genes,these
R9125 T12584 T12585 arg1Of this,does
R9126 T12584 T12587 arg1Of this,exclude
R9127 T12587 T12582 arg1Of exclude,However
R9128 T12587 T12583 arg1Of exclude,","
R9129 T12587 T12585 arg2Of exclude,does
R9130 T12587 T12586 arg1Of exclude,not
R9131 T12590 T12587 arg2Of effect,exclude
R9132 T12590 T12588 arg1Of effect,an
R9133 T12590 T12589 arg1Of effect,additional
R9134 T12590 T12591 arg1Of effect,of
R9135 T12590 T12593 arg1Of effect,on
R9136 T12592 T12591 arg2Of A20,of
R9137 T12596 T12593 arg2Of pathways,on
R9138 T12596 T12594 arg1Of pathways,other
R9139 T12596 T12595 arg1Of pathways,signaling
R9140 T12596 T12597 arg1Of pathways,that
R9141 T12596 T12598 arg1Of pathways,may
R9142 T12596 T12599 arg1Of pathways,contribute
R9143 T12599 T12598 arg2Of contribute,may
R9144 T12599 T12600 arg1Of contribute,to
R9145 T12603 T12600 arg2Of expression,to
R9146 T12603 T12601 arg1Of expression,proinflammatory
R9147 T12603 T12602 arg1Of expression,gene
R9148 T12604 T12605 arg1Of A20,is
R9149 T12604 T12606 arg2Of A20,believed
R9150 T12604 T12608 arg1Of A20,exert
R9151 T12604 T12616 arg1Of A20,modulating
R9152 T12606 T12605 arg2Of believed,is
R9153 T12608 T12606 arg3Of exert,believed
R9154 T12608 T12607 arg1Of exert,to
R9155 T12608 T12615 arg1Of exert,by
R9156 T12608 T12624 arg1Of exert,[
R9157 T12610 T12611 arg1Of NF-κB,and
R9158 T12612 T12611 arg2Of IRF3,and
R9159 T12614 T12608 arg2Of functions,exert
R9160 T12614 T12609 arg1Of functions,its
R9161 T12614 T12610 arg1Of functions,NF-κB
R9162 T12614 T12612 arg1Of functions,IRF3
R9163 T12614 T12613 arg1Of functions,inhibitory
R9164 T12616 T12615 arg2Of modulating,by
R9165 T12619 T12616 arg2Of status,modulating
R9166 T12619 T12617 arg1Of status,the
R9167 T12619 T12618 arg1Of status,ubiquitination
R9168 T12619 T12620 arg1Of status,of
R9169 T12623 T12620 arg2Of proteins,of
R9170 T12623 T12621 arg1Of proteins,different
R9171 T12623 T12622 arg1Of proteins,signaling
R9172 T12625 T12624 arg2Of 80,[
R9173 T12626 T12624 arg3Of ],[
R9174 T12629 T12627 arg2Of context,In
R9175 T12629 T12628 arg1Of context,this
R9176 T12631 T12632 arg1Of it,was
R9177 T12631 T12634 arg2Of it,shown
R9178 T12634 T12627 arg1Of shown,In
R9179 T12634 T12630 arg1Of shown,","
R9180 T12634 T12632 arg2Of shown,was
R9181 T12634 T12633 arg1Of shown,recently
R9182 T12636 T12637 arg1Of A20,cooperates
R9183 T12637 T12634 arg3Of cooperates,shown
R9184 T12637 T12635 arg1Of cooperates,that
R9185 T12637 T12638 arg1Of cooperates,with
R9186 T12637 T12645 arg1Of cooperates,to
R9187 T12637 T12651 arg1Of cooperates,","
R9188 T12637 T12654 modOf cooperates,affecting
R9189 T12641 T12639 arg1Of proteins,the
R9190 T12641 T12640 arg1Of proteins,ubiquitin-binding
R9191 T12642 T12643 arg1Of TAX1BP1,and
R9192 T12643 T12638 arg2Of and,with
R9193 T12643 T12641 arg1Of and,proteins
R9194 T12644 T12643 arg2Of ABIN1,and
R9195 T12647 T12637 arg2Of disrupt,cooperates
R9196 T12647 T12646 arg1Of disrupt,to
R9197 T12650 T12647 arg2Of complex,disrupt
R9198 T12650 T12648 arg1Of complex,the
R9199 T12650 T12649 arg1Of complex,TRAF3-TBK1-IKKε
R9200 T12654 T12652 arg1Of affecting,thereby
R9201 T12654 T12653 arg1Of affecting,negatively
R9202 T12654 T12670 arg1Of affecting,","
R9203 T12654 T12671 arg1Of affecting,[
R9204 T12655 T12654 arg2Of K63-polyubiquitination,affecting
R9205 T12655 T12656 arg1Of K63-polyubiquitination,of
R9206 T12657 T12658 arg1Of TBK1,and
R9207 T12658 T12661 arg1Of and,and
R9208 T12659 T12658 arg2Of IKKε,and
R9209 T12661 T12656 arg2Of and,of
R9210 T12661 T12660 arg1Of and,","
R9211 T12663 T12661 arg2Of ability,and
R9212 T12663 T12662 arg1Of ability,their
R9213 T12663 T12664 arg1Of ability,to
R9214 T12666 T12664 arg2Of IRF3,to
R9215 T12666 T12665 arg1Of IRF3,activity
R9216 T12666 T12667 arg1Of IRF3,[
R9217 T12668 T12667 arg2Of 81,[
R9218 T12669 T12667 arg3Of ],[
R9219 T12672 T12671 arg2Of 82,[
R9220 T12673 T12671 arg3Of ],[
R9221 T12676 T12675 arg1Of mechanisms,similar
R9222 T12676 T12677 arg1Of mechanisms,are
R9223 T12676 T12678 arg2Of mechanisms,involved
R9224 T12678 T12674 arg1Of involved,Whether
R9225 T12678 T12677 arg2Of involved,are
R9226 T12678 T12679 arg1Of involved,in
R9227 T12678 T12687 arg1Of involved,is
R9228 T12678 T12689 arg1Of involved,unclear
R9229 T12681 T12679 arg2Of regulation,in
R9230 T12681 T12680 arg1Of regulation,the
R9231 T12681 T12682 arg1Of regulation,of
R9232 T12683 T12682 arg2Of RIG-I,of
R9233 T12686 T12679 arg3Of activation,in
R9234 T12686 T12684 arg2Of activation,induced
R9235 T12686 T12685 arg1Of activation,NF-κB
R9236 T12687 T12688 arg1Of is,still
R9237 T12689 T12687 arg2Of unclear,is
R9238 T12691 T12690 arg1Of far,So
R9239 T12692 T12693 arg1Of we,were
R9240 T12692 T12694 arg1Of we,unable
R9241 T12692 T12697 arg1Of we,detect
R9242 T12692 T12707 arg1Of we,preventing
R9243 T12693 T12691 arg1Of were,far
R9244 T12694 T12693 arg2Of unable,were
R9245 T12697 T12694 arg2Of detect,unable
R9246 T12697 T12695 arg1Of detect,to
R9247 T12697 T12696 arg1Of detect,clearly
R9248 T12697 T12706 arg1Of detect,","
R9249 T12697 T12707 modOf detect,preventing
R9250 T12698 T12697 arg2Of ubiquitination,detect
R9251 T12698 T12699 arg1Of ubiquitination,of
R9252 T12698 T12703 arg1Of ubiquitination,in
R9253 T12700 T12701 arg1Of TBK1,and
R9254 T12701 T12699 arg2Of and,of
R9255 T12702 T12701 arg2Of IKKε,and
R9256 T12705 T12703 arg2Of macrophages,in
R9257 T12705 T12704 arg1Of macrophages,primary
R9258 T12707 T12709 arg1Of preventing,from
R9259 T12708 T12707 arg2Of us,preventing
R9260 T12710 T12709 arg2Of studying,from
R9261 T12712 T12710 arg2Of effect,studying
R9262 T12712 T12711 arg1Of effect,the
R9263 T12712 T12713 arg1Of effect,of
R9264 T12712 T12716 arg1Of effect,on
R9265 T12715 T12713 arg2Of deficiency,of
R9266 T12715 T12714 arg1Of deficiency,A20
R9267 T12719 T12716 arg2Of status,on
R9268 T12719 T12717 arg1Of status,their
R9269 T12719 T12718 arg1Of status,ubiquitination
R9270 T12720 T12721 arg1Of It,can
R9271 T12720 T12723 arg1Of It,be
R9272 T12720 T12724 arg2Of It,excluded
R9273 T12724 T12721 arg2Of excluded,can
R9274 T12724 T12722 arg1Of excluded,not
R9275 T12724 T12723 arg2Of excluded,be
R9276 T12724 T12725 arg1Of excluded,however
R9277 T12727 T12726 arg1Of A20,that
R9278 T12727 T12729 arg1Of A20,targets
R9279 T12729 T12725 arg2Of targets,however
R9280 T12729 T12728 arg1Of targets,also
R9281 T12731 T12729 arg2Of substrates,targets
R9282 T12731 T12730 arg1Of substrates,other
R9283 T12731 T12732 arg1Of substrates,that
R9284 T12731 T12733 arg1Of substrates,mediate
R9285 T12733 T12738 arg1Of mediate,in
R9286 T12734 T12735 arg1Of NF-κB,and
R9287 T12735 T12733 arg2Of and,mediate
R9288 T12737 T12735 arg2Of activation,and
R9289 T12737 T12736 arg1Of activation,IRF3
R9290 T12740 T12738 arg2Of cells,in
R9291 T12740 T12739 arg1Of cells,myeloid
R9292 T12742 T12741 arg1Of identification,The
R9293 T12742 T12743 arg1Of identification,of
R9294 T12742 T12746 arg1Of identification,will
R9295 T12742 T12747 arg1Of identification,be
R9296 T12745 T12743 arg2Of substrates,of
R9297 T12745 T12744 arg1Of substrates,these
R9298 T12747 T12746 arg2Of be,will
R9299 T12747 T12753 arg1Of be,in
R9300 T12749 T12747 arg2Of topic,be
R9301 T12749 T12748 arg1Of topic,the
R9302 T12749 T12750 arg1Of topic,of
R9303 T12752 T12750 arg2Of investigations,of
R9304 T12752 T12751 arg1Of investigations,future
R9305 T12755 T12753 arg2Of laboratory,in
R9306 T12755 T12754 arg1Of laboratory,our
R9307 T12759 T12756 arg1Of enzymes,Multiple
R9308 T12759 T12757 arg1Of enzymes,other
R9309 T12759 T12758 arg1Of enzymes,deubiquitinating
R9310 T12759 T12760 arg1Of enzymes,(
R9311 T12759 T12763 arg1Of enzymes,","
R9312 T12759 T12765 arg1Of enzymes,as
R9313 T12761 T12760 arg2Of DUBs,(
R9314 T12762 T12760 arg3Of ),(
R9315 T12765 T12764 arg1Of as,such
R9316 T12766 T12767 arg1Of DUBA,[
R9317 T12766 T12770 arg1Of DUBA,","
R9318 T12768 T12767 arg2Of 28,[
R9319 T12769 T12767 arg3Of ],[
R9320 T12770 T12775 arg1Of ",",","
R9321 T12770 T12776 arg1Of ",",[
R9322 T12770 T12779 arg1Of ",",","
R9323 T12770 T12785 arg1Of ",",and
R9324 T12771 T12770 arg2Of CYLD,","
R9325 T12771 T12772 arg1Of CYLD,[
R9326 T12773 T12772 arg2Of 29,[
R9327 T12774 T12772 arg3Of ],[
R9328 T12777 T12776 arg2Of 30,[
R9329 T12778 T12776 arg3Of ],[
R9330 T12780 T12779 arg2Of OTUB1/2,","
R9331 T12780 T12781 arg1Of OTUB1/2,[
R9332 T12782 T12781 arg2Of 31,[
R9333 T12783 T12781 arg3Of ],[
R9334 T12785 T12765 arg2Of and,as
R9335 T12785 T12784 arg1Of and,","
R9336 T12786 T12785 arg2Of A20,and
R9337 T12786 T12787 arg1Of A20,[
R9338 T12786 T12794 modOf A20,have
R9339 T12788 T12787 arg2Of 49,[
R9340 T12789 T12787 arg3Of ],[
R9341 T12790 T12791 arg1Of –,[
R9342 T12790 T12794 arg1Of –,have
R9343 T12790 T12795 arg1Of –,been
R9344 T12790 T12796 arg2Of –,shown
R9345 T12790 T12799 arg1Of –,regulate
R9346 T12792 T12791 arg2Of 52,[
R9347 T12793 T12791 arg3Of ],[
R9348 T12796 T12794 arg2Of shown,have
R9349 T12796 T12795 arg2Of shown,been
R9350 T12796 T12806 arg1Of shown,","
R9351 T12796 T12807 modOf shown,implicating
R9352 T12799 T12796 arg3Of regulate,shown
R9353 T12799 T12797 arg1Of regulate,to
R9354 T12799 T12798 arg1Of regulate,negatively
R9355 T12801 T12799 arg2Of signaling,regulate
R9356 T12801 T12800 arg1Of signaling,RIG-I
R9357 T12801 T12802 arg1Of signaling,to
R9358 T12803 T12804 arg1Of NF-κB,and
R9359 T12804 T12802 arg2Of and,to
R9360 T12805 T12804 arg2Of IRF-3,and
R9361 T12809 T12807 arg2Of redundancy,implicating
R9362 T12809 T12808 arg1Of redundancy,possible
R9363 T12812 T12815 arg1Of evidence,was
R9364 T12812 T12816 arg2Of evidence,limited
R9365 T12812 T12822 arg1Of evidence,was
R9366 T12812 T12823 arg2Of evidence,obtained
R9367 T12814 T12813 arg1Of far,so
R9368 T12816 T12815 arg2Of limited,was
R9369 T12816 T12817 arg1Of limited,to
R9370 T12816 T12821 arg1Of limited,and
R9371 T12819 T12818 arg1Of vitro,in
R9372 T12820 T12817 arg2Of data,to
R9373 T12820 T12819 arg1Of data,vitro
R9374 T12821 T12810 arg1Of and,However
R9375 T12821 T12811 arg1Of and,","
R9376 T12821 T12814 arg1Of and,far
R9377 T12823 T12821 arg2Of obtained,and
R9378 T12823 T12822 arg2Of obtained,was
R9379 T12823 T12824 arg1Of obtained,under
R9380 T12826 T12824 arg2Of conditions,under
R9381 T12826 T12825 arg1Of conditions,non-physiological
R9382 T12830 T12827 arg1Of phenotype,The
R9383 T12830 T12828 arg1Of phenotype,clear
R9384 T12830 T12829 arg1Of phenotype,protective
R9385 T12830 T12831 arg1Of phenotype,of
R9386 T12830 T12834 arg1Of phenotype,that
R9387 T12830 T12837 arg2Of phenotype,describe
R9388 T12830 T12838 arg1Of phenotype,indicates
R9389 T12833 T12831 arg2Of mice,of
R9390 T12833 T12832 arg1Of mice,A20myel-KO
R9391 T12835 T12837 arg1Of we,describe
R9392 T12837 T12836 arg1Of describe,here
R9393 T12841 T12840 arg1Of expression,A20
R9394 T12841 T12842 arg1Of expression,in
R9395 T12841 T12845 arg1Of expression,is
R9396 T12844 T12842 arg2Of cells,in
R9397 T12844 T12843 arg1Of cells,myeloid
R9398 T12845 T12839 arg1Of is,that
R9399 T12845 T12853 arg1Of is,in
R9400 T12845 T12858 arg1Of is,and
R9401 T12848 T12845 arg2Of gatekeeper,is
R9402 T12848 T12846 arg1Of gatekeeper,a
R9403 T12848 T12847 arg1Of gatekeeper,central
R9404 T12848 T12849 arg1Of gatekeeper,of
R9405 T12852 T12849 arg2Of signaling,of
R9406 T12852 T12850 arg1Of signaling,RIG-I
R9407 T12852 T12851 arg2Of signaling,induced
R9408 T12853 T12855 arg1Of in,to
R9409 T12854 T12853 arg2Of response,in
R9410 T12857 T12853 arg3Of infection,in
R9411 T12857 T12856 arg1Of infection,IAV
R9412 T12858 T12838 arg2Of and,indicates
R9413 T12859 T12858 arg2Of that,and
R9414 T12861 T12860 arg1Of DUBs,other
R9415 T12861 T12862 arg1Of DUBs,can
R9416 T12861 T12864 arg1Of DUBs,substitute
R9417 T12864 T12859 arg2Of substitute,that
R9418 T12864 T12862 arg2Of substitute,can
R9419 T12864 T12863 arg1Of substitute,not
R9420 T12864 T12865 arg1Of substitute,for
R9421 T12864 T12868 arg1Of substitute,under
R9422 T12867 T12865 arg2Of deficiency,for
R9423 T12867 T12866 arg1Of deficiency,A20
R9424 T12870 T12868 arg2Of conditions,under
R9425 T12870 T12869 arg1Of conditions,physiological
R9426 T12872 T12873 arg1Of A20,has
R9427 T12873 T12871 arg1Of has,If
R9428 T12873 T12897 arg1Of has,remains
R9429 T12873 T12899 arg1Of has,be
R9430 T12873 T12900 arg2Of has,investigated
R9431 T12877 T12873 arg2Of role,has
R9432 T12877 T12874 arg1Of role,a
R9433 T12877 T12875 arg1Of role,similar
R9434 T12877 T12876 arg1Of role,non-redundant
R9435 T12877 T12878 arg1Of role,in
R9436 T12877 T12890 arg1Of role,","
R9437 T12877 T12892 arg1Of role,as
R9438 T12881 T12878 arg2Of types,in
R9439 T12881 T12879 arg1Of types,other
R9440 T12881 T12880 arg1Of types,cell
R9441 T12881 T12882 arg1Of types,that
R9442 T12881 T12883 arg1Of types,are
R9443 T12881 T12884 arg2Of types,implicated
R9444 T12884 T12883 arg2Of implicated,are
R9445 T12884 T12885 arg1Of implicated,in
R9446 T12887 T12885 arg2Of response,in
R9447 T12887 T12886 arg1Of response,the
R9448 T12887 T12888 arg1Of response,to
R9449 T12889 T12888 arg2Of IAV,to
R9450 T12892 T12891 arg1Of as,such
R9451 T12895 T12892 arg2Of cells,as
R9452 T12895 T12893 arg1Of cells,lung
R9453 T12895 T12894 arg1Of cells,epithelial
R9454 T12897 T12896 arg1Of remains,","
R9455 T12900 T12897 arg2Of investigated,remains
R9456 T12900 T12898 arg1Of investigated,to
R9457 T12900 T12899 arg2Of investigated,be

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T11814 1341-1345 Antecedent denotes IKKε
T11813 1332-1336 Antecedent denotes TBK1
T11812 1430-1435 Anaphor denotes their
T11811 1111-1115 Antecedent denotes IKKε
T11810 1102-1106 Antecedent denotes TBK1
T11809 1121-1126 Anaphor denotes their
R8525 T11809 T11810 boundBy their,TBK1
R8526 T11809 T11811 boundBy their,IKKε
R8527 T11812 T11813 boundBy their,TBK1
R8528 T11812 T11814 boundBy their,IKKε

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T11844 2163-2168 Protein denotes RIG-I
T11843 1870-1875 Protein denotes IRF-3
T11842 1841-1846 Protein denotes RIG-I
T11841 1753-1757 Protein denotes CYLD
T11840 1551-1555 Protein denotes IRF3
T11839 1341-1345 Protein denotes IKKε
T11838 1332-1336 Protein denotes TBK1
T11837 1225-1230 Protein denotes RIG-I
T11836 1147-1151 Protein denotes IRF3
T11835 1111-1115 Protein denotes IKKε
T11834 1102-1106 Protein denotes TBK1
T11833 998-1003 Protein denotes ABIN1
T11832 787-791 Protein denotes IRF3
T11831 534-538 Protein denotes IRF3
T11830 493-497 Protein denotes IFNβ
T11829 482-487 Protein denotes MIP-2
T11828 478-480 Protein denotes KC
T11827 472-476 Protein denotes IL-6
T11826 467-470 Protein denotes TNF
T11825 345-350 Protein denotes RIG-I
T11824 146-151 Protein denotes RIG-I
T11823 90-95 Protein denotes RIG-I
T11822 59-63 Protein denotes IRF3

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T14295 1332-1336 http://www.uniprot.org/uniprot/Q9UHD2 denotes TBK1
T14294 1102-1106 http://www.uniprot.org/uniprot/Q9UHD2 denotes TBK1
T14293 1028-1032 http://www.uniprot.org/uniprot/Q9UHD2 denotes TBK1
T14292 1022-1027 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T14291 986-993 http://www.uniprot.org/uniprot/Q86VP1 denotes TAX1BP1
T14290 1870-1875 http://www.uniprot.org/uniprot/Q14653 denotes IRF-3
T14289 1551-1555 http://www.uniprot.org/uniprot/Q14653 denotes IRF3
T14288 1147-1151 http://www.uniprot.org/uniprot/Q14653 denotes IRF3
T14287 787-791 http://www.uniprot.org/uniprot/Q14653 denotes IRF3
T14286 534-538 http://www.uniprot.org/uniprot/Q14653 denotes IRF3
T14285 59-63 http://www.uniprot.org/uniprot/Q14653 denotes IRF3
T14283 467-470 http://www.uniprot.org/uniprot/P01375 denotes TNF
T14281 472-476 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T14279 482-487 http://www.uniprot.org/uniprot/P10889 denotes MIP-2
T14274 2308-2311 http://www.uniprot.org/uniprot/P21580 denotes A20
T14273 2258-2261 http://www.uniprot.org/uniprot/P21580 denotes A20
T14272 2104-2107 http://www.uniprot.org/uniprot/P21580 denotes A20
T14271 1788-1791 http://www.uniprot.org/uniprot/P21580 denotes A20
T14270 1494-1497 http://www.uniprot.org/uniprot/P21580 denotes A20
T14269 1412-1415 http://www.uniprot.org/uniprot/P21580 denotes A20
T14268 935-938 http://www.uniprot.org/uniprot/P21580 denotes A20
T14267 748-751 http://www.uniprot.org/uniprot/P21580 denotes A20
T14266 660-663 http://www.uniprot.org/uniprot/P21580 denotes A20
T14265 378-381 http://www.uniprot.org/uniprot/P21580 denotes A20
T14264 13-16 http://www.uniprot.org/uniprot/P21580 denotes A20

UBERON-AE

Id Subject Object Predicate Lexical cue
T11701 2141-2148 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
T11698 2417-2421 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T11697 312-316 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

GO-BP

Id Subject Object Predicate Lexical cue
T11902 1701-1725 http://purl.obolibrary.org/obo/GO_0004843 denotes deubiquitinating enzymes
T11901 1556-1583 http://purl.obolibrary.org/obo/GO_0001773 denotes activation in myeloid cells
T11900 1556-1583 http://purl.obolibrary.org/obo/GO_0045639 denotes activation in myeloid cells
T11899 1556-1583 http://purl.obolibrary.org/obo/GO_0033034 denotes activation in myeloid cells
T11898 1239-1255 http://purl.obolibrary.org/obo/GO_0051092 denotes NF-κB activation
T11897 1211-1221 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11896 1332-1336 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11895 1102-1106 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11894 1028-1032 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11893 673-691 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T11892 731-746 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T11891 419-434 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T11890 2177-2186 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11889 1847-1856 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11888 866-875 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11887 673-682 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11886 351-360 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11885 1841-1856 http://purl.obolibrary.org/obo/GO_0039529 denotes RIG-I signaling
T11884 345-360 http://purl.obolibrary.org/obo/GO_0039529 denotes RIG-I signaling
T11869 270-285 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11868 211-226 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11865 204-226 http://purl.obolibrary.org/obo/GO_0045824 denotes innate immune response
T11862 204-226 http://purl.obolibrary.org/obo/GO_0045089 denotes innate immune response
T11859 204-226 http://purl.obolibrary.org/obo/GO_0002218 denotes innate immune response
T11856 204-226 http://purl.obolibrary.org/obo/GO_0045088 denotes innate immune response
T11853 204-226 http://purl.obolibrary.org/obo/GO_0002227 denotes innate immune response
T11850 204-226 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune response

GO-MF

Id Subject Object Predicate Lexical cue
T11924 1701-1725 http://purl.obolibrary.org/obo/GO_0004843 denotes deubiquitinating enzymes
T11923 1332-1336 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11922 1102-1106 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11921 1028-1032 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T11920 969-985 http://purl.obolibrary.org/obo/GO_0005515 denotes binding proteins
T11919 969-976 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T11918 959-985 http://purl.obolibrary.org/obo/GO_0032182 denotes ubiquitin-binding proteins
T11917 959-985 http://purl.obolibrary.org/obo/GO_0031625 denotes ubiquitin-binding proteins
T11916 959-976 http://purl.obolibrary.org/obo/GO_0043130 denotes ubiquitin-binding
T11915 959-968 http://purl.obolibrary.org/obo/GO_0031386 denotes ubiquitin
T11911 472-476 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6

GO-CC

Id Subject Object Predicate Lexical cue
T11936 2433-2438 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T11935 2130-2135 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T11934 1578-1583 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T11731 2305-2467 Sentence denotes If A20 has a similar non-redundant role in other cell types that are implicated in the response to IAV, such as lung epithelial cells, remains to be investigated.
T11730 2017-2304 Sentence denotes The clear protective phenotype of A20myel-KO mice that we here describe indicates that A20 expression in myeloid cells is a central gatekeeper of RIG-I induced signaling in response to IAV infection and that other DUBs cannot substitute for A20 deficiency under physiological conditions.
T11729 1910-2016 Sentence denotes However, evidence so far was limited to in vitro data and was obtained under non-physiological conditions.
T11728 1686-1909 Sentence denotes Multiple other deubiquitinating enzymes (DUBs), such as DUBA [28], CYLD [29], [30], OTUB1/2 [31], and A20 [49]–[52] have been shown to negatively regulate RIG-I signaling to NF-κB and IRF-3, implicating possible redundancy.
T11727 1585-1685 Sentence denotes The identification of these substrates will be the topic of future investigations in our laboratory.
T11726 1459-1584 Sentence denotes It cannot be excluded however that A20 also targets other substrates that mediate NF-κB and IRF3 activation in myeloid cells.
T11725 1274-1458 Sentence denotes So far we were unable to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20 deficiency on their ubiquitination status.
T11724 1164-1273 Sentence denotes Whether similar mechanisms are involved in the regulation of RIG-I induced NF-κB activation is still unclear.
T11723 891-1163 Sentence denotes In this context, it was recently shown that A20 cooperates with the ubiquitin-binding proteins TAX1BP1 and ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex, thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε, and their ability to activity IRF3 [81], [82].
T11722 748-890 Sentence denotes A20 is believed to exert its NF-κB and IRF3 inhibitory functions by modulating the ubiquitination status of different signaling proteins [80].
T11721 605-747 Sentence denotes However, this does not exclude an additional effect of A20 on other signaling pathways that may contribute to proinflammatory gene expression.
T11720 362-604 Sentence denotes We propose that A20 inhibits IAV-induced proinflammatory gene expression (as shown in our manuscript for TNF, IL-6, KC, MIP-2, and IFNβ) by negatively regulating NF-κB and IRF3 activation, which are the major pathways controlling these genes.
T11719 146-361 Sentence denotes RIG-I has previously been shown to play a key role in the innate immune response to IAV [13], suggesting that the increased immune response of A20myel-KO mice to IAV lung infection reflects enhanced RIG-I signaling.
T11718 0-145 Sentence denotes We show that A20 deficient BMDM display enhanced NF-κB and IRF3 activation in response to RIG-I stimulation by synthetic LMW double stranded RNA.
T172 0-145 Sentence denotes We show that A20 deficient BMDM display enhanced NF-κB and IRF3 activation in response to RIG-I stimulation by synthetic LMW double stranded RNA.
T173 146-361 Sentence denotes RIG-I has previously been shown to play a key role in the innate immune response to IAV [13], suggesting that the increased immune response of A20myel-KO mice to IAV lung infection reflects enhanced RIG-I signaling.
T174 362-604 Sentence denotes We propose that A20 inhibits IAV-induced proinflammatory gene expression (as shown in our manuscript for TNF, IL-6, KC, MIP-2, and IFNβ) by negatively regulating NF-κB and IRF3 activation, which are the major pathways controlling these genes.
T175 605-747 Sentence denotes However, this does not exclude an additional effect of A20 on other signaling pathways that may contribute to proinflammatory gene expression.
T176 748-890 Sentence denotes A20 is believed to exert its NF-κB and IRF3 inhibitory functions by modulating the ubiquitination status of different signaling proteins [80].
T177 891-1163 Sentence denotes In this context, it was recently shown that A20 cooperates with the ubiquitin-binding proteins TAX1BP1 and ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex, thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε, and their ability to activity IRF3 [81], [82].
T178 1164-1273 Sentence denotes Whether similar mechanisms are involved in the regulation of RIG-I induced NF-κB activation is still unclear.
T179 1274-1458 Sentence denotes So far we were unable to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20 deficiency on their ubiquitination status.
T180 1459-1584 Sentence denotes It cannot be excluded however that A20 also targets other substrates that mediate NF-κB and IRF3 activation in myeloid cells.
T181 1585-1685 Sentence denotes The identification of these substrates will be the topic of future investigations in our laboratory.
T182 1686-1909 Sentence denotes Multiple other deubiquitinating enzymes (DUBs), such as DUBA [28], CYLD [29], [30], OTUB1/2 [31], and A20 [49]–[52] have been shown to negatively regulate RIG-I signaling to NF-κB and IRF-3, implicating possible redundancy.
T183 1910-2016 Sentence denotes However, evidence so far was limited to in vitro data and was obtained under non-physiological conditions.
T184 2017-2304 Sentence denotes The clear protective phenotype of A20myel-KO mice that we here describe indicates that A20 expression in myeloid cells is a central gatekeeper of RIG-I induced signaling in response to IAV infection and that other DUBs cannot substitute for A20 deficiency under physiological conditions.
T185 2305-2467 Sentence denotes If A20 has a similar non-redundant role in other cell types that are implicated in the response to IAV, such as lung epithelial cells, remains to be investigated.

simple1

Id Subject Object Predicate Lexical cue
T11998 2163-2168 Protein denotes RIG-I
T11997 1870-1875 Protein denotes IRF-3
T11996 1841-1846 Protein denotes RIG-I
T11995 1753-1757 Protein denotes CYLD
T11994 1551-1555 Protein denotes IRF3
T11993 1341-1345 Protein denotes IKKε
T11992 1332-1336 Protein denotes TBK1
T11991 1225-1230 Protein denotes RIG-I
T11990 1147-1151 Protein denotes IRF3
T11989 1111-1115 Protein denotes IKKε
T11988 1102-1106 Protein denotes TBK1
T11987 998-1003 Protein denotes ABIN1
T11986 787-791 Protein denotes IRF3
T11985 534-538 Protein denotes IRF3
T11984 493-497 Protein denotes IFNβ
T11983 482-487 Protein denotes MIP-2
T11982 478-480 Protein denotes KC
T11981 472-476 Protein denotes IL-6
T11980 467-470 Protein denotes TNF
T11979 345-350 Protein denotes RIG-I
T11978 146-151 Protein denotes RIG-I
T11977 90-95 Protein denotes RIG-I
T11976 59-63 Protein denotes IRF3

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T14596 1533-1540 Positive_regulation denotes mediate
T14595 1556-1566 Positive_regulation denotes activation
T14594 1314-1328 Binding denotes ubiquitination
T14593 1211-1221 Regulation denotes regulation
T14592 539-549 Positive_regulation denotes activation
T14591 64-74 Positive_regulation denotes activation
T14590 40-48 Positive_regulation denotes enhanced
T14585 2163-2168 Protein denotes RIG-I
T14584 1870-1875 Protein denotes IRF-3
T14583 1841-1846 Protein denotes RIG-I
T14582 1753-1757 Protein denotes CYLD
T14581 1551-1555 Protein denotes IRF3
T14580 1341-1345 Protein denotes IKKε
T14579 1332-1336 Protein denotes TBK1
T14578 1225-1230 Protein denotes RIG-I
T14577 1147-1151 Protein denotes IRF3
T14576 1111-1115 Protein denotes IKKε
T14575 1102-1106 Protein denotes TBK1
T14574 998-1003 Protein denotes ABIN1
T14573 787-791 Protein denotes IRF3
T14572 534-538 Protein denotes IRF3
T14571 493-497 Protein denotes IFNβ
T14570 482-487 Protein denotes MIP-2
T14569 478-480 Protein denotes KC
T14568 472-476 Protein denotes IL-6
T14567 467-470 Protein denotes TNF
T14566 345-350 Protein denotes RIG-I
T14565 146-151 Protein denotes RIG-I
T14564 90-95 Protein denotes RIG-I
T14563 59-63 Protein denotes IRF3
R10918 T14563 T14591 themeOf IRF3,activation
R10919 T14572 T14592 themeOf IRF3,activation
R10920 T14578 T14593 themeOf RIG-I,regulation
R10923 T14579 T14594 themeOf TBK1,ubiquitination
R10925 T14580 T14594 themeOf IKKε,ubiquitination
R10926 T14581 T14595 themeOf IRF3,activation
R10927 T14591 T14590 themeOf activation,enhanced
R10931 T14595 T14596 themeOf activation,mediate

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T14336 1556-1566 Positive_regulation denotes activation
T14335 1533-1540 Positive_regulation denotes mediate
T14334 1314-1328 Binding denotes ubiquitination
T14333 1231-1238 Positive_regulation denotes induced
T14332 1245-1255 Positive_regulation denotes activation
T14331 1211-1221 Regulation denotes regulation
T14330 40-48 Positive_regulation denotes enhanced
T14329 64-74 Positive_regulation denotes activation
T14325 2163-2168 Protein denotes RIG-I
T14323 1841-1846 Protein denotes RIG-I
T14322 1753-1757 Protein denotes CYLD
T14321 1551-1555 Protein denotes IRF3
T14320 1341-1345 Protein denotes IKKε
T14319 1332-1336 Protein denotes TBK1
T14318 1225-1230 Protein denotes RIG-I
T14317 1147-1151 Protein denotes IRF3
T14316 1111-1115 Protein denotes IKKε
T14315 1102-1106 Protein denotes TBK1
T14314 998-1003 Protein denotes ABIN1
T14313 787-791 Protein denotes IRF3
T14312 534-538 Protein denotes IRF3
T14311 493-497 Protein denotes IFNβ
T14310 482-487 Protein denotes MIP-2
T14309 478-480 Protein denotes KC
T14308 472-476 Protein denotes IL-6
T14307 467-470 Protein denotes TNF
T14306 345-350 Protein denotes RIG-I
T14305 146-151 Protein denotes RIG-I
T14304 90-95 Protein denotes RIG-I
T14303 59-63 Protein denotes IRF3
T14324 1870-1875 Protein denotes IRF-3
R10827 T14303 T14329 themeOf IRF3,activation
R10828 T14318 T14332 themeOf RIG-I,activation
R10829 T14319 T14334 themeOf TBK1,ubiquitination
R10830 T14329 T14330 themeOf activation,enhanced
R10831 T14320 T14334 themeOf IKKε,ubiquitination
R10832 T14321 T14336 themeOf IRF3,activation
R10833 T14332 T14333 themeOf activation,induced
R10834 T14332 T14331 themeOf activation,regulation
R10835 T14336 T14335 themeOf activation,mediate

DLUT931

Id Subject Object Predicate Lexical cue
T14386 2149-2159 Regulation denotes gatekeeper
T14385 2169-2176 Positive_regulation denotes induced
T14384 1533-1540 Positive_regulation denotes mediate
T14383 1556-1566 Positive_regulation denotes activation
T14382 1314-1328 Ubiquitination denotes ubiquitination
T14381 1195-1203 Regulation denotes involved
T14380 1231-1238 Positive_regulation denotes induced
T14379 1211-1221 Regulation denotes regulation
T14378 1245-1255 Positive_regulation denotes activation
T14377 1066-1075 Positive_regulation denotes affecting
T14376 1076-1098 Positive_regulation denotes K63-polyubiquitination
T14375 959-976 Binding denotes ubiquitin-binding
T14374 513-523 Regulation denotes regulating
T14373 336-344 Positive_regulation denotes enhanced
T14372 78-86 Positive_regulation denotes response
T14371 40-48 Positive_regulation denotes enhanced
T14370 96-107 Positive_regulation denotes stimulation
T14369 64-74 Positive_regulation denotes activation
T14366 2163-2168 Protein denotes RIG-I
T14365 1870-1875 Protein denotes IRF-3
T14364 1841-1846 Protein denotes RIG-I
T14363 1753-1757 Protein denotes CYLD
T14362 1551-1555 Protein denotes IRF3
T14361 1341-1345 Protein denotes IKKε
T14360 1332-1336 Protein denotes TBK1
T14359 1225-1230 Protein denotes RIG-I
T14358 1147-1151 Protein denotes IRF3
T14357 1111-1115 Protein denotes IKKε
T14356 1102-1106 Protein denotes TBK1
T14355 998-1003 Protein denotes ABIN1
T14354 787-791 Protein denotes IRF3
T14353 534-538 Protein denotes IRF3
T14352 493-497 Protein denotes IFNβ
T14351 482-487 Protein denotes MIP-2
T14350 478-480 Protein denotes KC
T14349 472-476 Protein denotes IL-6
T14348 467-470 Protein denotes TNF
T14347 345-350 Protein denotes RIG-I
T14346 146-151 Protein denotes RIG-I
T14345 90-95 Protein denotes RIG-I
T14344 59-63 Protein denotes IRF3
R10836 T14353 T14374 themeOf IRF3,regulating
R10837 T14355 T14375 themeOf ABIN1,ubiquitin-binding
R10838 T14356 T14376 themeOf TBK1,K63-polyubiquitination
R10839 T14357 T14376 themeOf IKKε,K63-polyubiquitination
R10840 T14359 T14378 themeOf RIG-I,activation
R10841 T14360 T14382 themeOf TBK1,ubiquitination
R10842 T14361 T14382 themeOf IKKε,ubiquitination
R10843 T14362 T14383 themeOf IRF3,activation
R10844 T14366 T14385 themeOf RIG-I,induced
R10847 T14344 T14369 themeOf IRF3,activation
R10848 T14369 T14371 themeOf activation,enhanced
R10849 T14345 T14370 themeOf RIG-I,stimulation
R10850 T14347 T14373 themeOf RIG-I,enhanced
R10851 T14370 T14372 themeOf stimulation,response
R10852 T14372 T14370 themeOf response,stimulation
R10853 T14372 T14371 themeOf response,enhanced
R10854 T14376 T14377 themeOf K63-polyubiquitination,affecting
R10855 T14376 T14377 themeOf K63-polyubiquitination,affecting
R10856 T14378 T14379 themeOf activation,regulation
R10857 T14378 T14380 themeOf activation,induced
R10858 T14379 T14381 themeOf regulation,involved
R10859 T14379 T14378 themeOf regulation,activation
R10860 T14380 T14378 themeOf induced,activation
R10862 T14383 T14384 themeOf activation,mediate
R10866 T14385 T14386 themeOf induced,gatekeeper

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Negation
T14760 2104-2135 Gene_expression denotes A20 expression in myeloid cells
T14759 1204-1238 Regulation denotes in the regulation of RIG-I induced
T14757 969-985 Binding denotes binding proteins
T14756 1296-1415 Ubiquitination denotes to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20
T14755 1296-1415 Ubiquitination denotes to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20
T14754 1047-1115 Regulation denotes thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε
T14753 1047-1115 Regulation denotes thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε
T14752 2163-2176 Gene_expression denotes RIG-I induced
T14751 2163-2176 Positive_regulation denotes RIG-I induced
T14750 1076-1115 Ubiquitination denotes K63-polyubiquitination of TBK1 and IKKε
T14749 1076-1115 Ubiquitination denotes K63-polyubiquitination of TBK1 and IKKε
T14748 1010-1037 Negative_regulation denotes disrupt the TRAF3-TBK1-IKKε
T14747 1010-1037 Negative_regulation denotes disrupt the TRAF3-TBK1-IKKε
T14746 1010-1037 Negative_regulation denotes disrupt the TRAF3-TBK1-IKKε
T14745 853-889 Positive_regulation denotes of different signaling proteins [80]
T14744 614-746 Regulation denotes this does not exclude an additional effect of A20 on other signaling pathways that may contribute to proinflammatory gene expression true
T14742 1841-1856 Positive_regulation denotes RIG-I signaling
T14741 59-74 Positive_regulation denotes IRF3 activation
T14740 373-434 Negative_regulation denotes that A20 inhibits IAV-induced proinflammatory gene expression
T14739 998-1045 Binding denotes ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex
T14738 2163-2186 Positive_regulation denotes RIG-I induced signaling
T14736 336-360 Positive_regulation denotes enhanced RIG-I signaling
T14735 336-360 Positive_regulation denotes enhanced RIG-I signaling
T14734 534-550 Positive_regulation denotes IRF3 activation,
T14733 90-107 Positive_regulation denotes RIG-I stimulation
T14732 561-603 Regulation denotes the major pathways controlling these genes
T14731 1239-1255 Positive_regulation denotes NF-κB activation
T14730 1551-1566 Positive_regulation denotes IRF3 activation
T14725 1022-1027 Protein denotes TRAF3
T14723 2348-2407 Entity denotes other cell types that are implicated in the response to IAV
T14721 49-54 Protein denotes NF-κB
T14719 1332-1336 Protein denotes TBK1
T14718 2104-2107 Protein denotes A20
T14717 1788-1796 Protein denotes A20 [49]
T14716 959-985 Protein denotes ubiquitin-binding proteins
T14715 482-487 Protein denotes MIP-2
T14713 1409-1415 Protein denotes of A20
T14711 955-993 Protein denotes the ubiquitin-binding proteins TAX1BP1
T14710 935-938 Protein denotes A20
T14709 1727-1731 Protein denotes DUBs
T14708 959-985 Protein denotes ubiquitin-binding proteins
T14707 534-538 Protein denotes IRF3
T14706 472-476 Protein denotes IL-6
T14705 2163-2176 Protein denotes RIG-I induced
T14702 1028-1032 Protein denotes TBK1
T14701 1076-1079 Entity denotes K63
T14699 592-603 Protein denotes these genes
T14697 90-95 Protein denotes RIG-I
T14696 345-350 Protein denotes RIG-I
T14695 1222-1230 Protein denotes of RIG-I
T14694 1341-1345 Protein denotes IKKε
T14690 1718-1733 Protein denotes enzymes (DUBs),
T14688 2062-2066 Protein denotes mice
T14686 777-782 Protein denotes NF-κB
T14683 1686-1700 Entity denotes Multiple other
T14682 969-985 Protein denotes binding proteins
T14680 1860-1865 Protein denotes NF-κB
T14676 657-663 Protein denotes of A20
T14675 493-497 Protein denotes IFNβ
T14673 998-1045 Protein denotes ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex
T14670 8-16 Protein denotes that A20
T14669 2254-2272 Protein denotes for A20 deficiency
T14668 1511-1583 Entity denotes other substrates that mediate NF-κB and IRF3 activation in myeloid cells
T14666 1022-1037 Protein denotes TRAF3-TBK1-IKKε
T14662 378-381 Protein denotes A20
T14660 467-470 Protein denotes TNF
T14659 787-791 Protein denotes IRF3
T14658 1147-1156 Protein denotes IRF3 [81]
T14655 1239-1244 Protein denotes NF-κB
T14653 1604-1623 Entity denotes of these substrates
T14652 748-751 Protein denotes A20
T14647 1742-1752 Protein denotes DUBA [28],
T14645 1111-1115 Protein denotes IKKε
T14640 1841-1846 Protein denotes RIG-I
T14639 1349-1369 Entity denotes primary macrophages,
T14638 2122-2135 Entity denotes myeloid cells
T14637 1570-1583 Entity denotes myeloid cells
T14631 1870-1875 Protein denotes IRF-3
T14629 853-889 Protein denotes of different signaling proteins [80]
T14628 1541-1546 Protein denotes NF-κB
T14623 146-151 Protein denotes RIG-I
T14622 2225-2235 Protein denotes other DUBs
T14621 59-63 Protein denotes IRF3
T14620 1489-1497 Protein denotes that A20
T14619 2308-2311 Protein denotes A20
T14616 1742-1768 Protein denotes DUBA [28], CYLD [29], [30]
T14615 478-480 Protein denotes KC
T14612 1551-1555 Protein denotes IRF3
T14609 1770-1782 Protein denotes OTUB1/2 [31]
T14608 2417-2439 Entity denotes lung epithelial cells,
T14601 524-529 Protein denotes NF-κB
T14598 1102-1106 Protein denotes TBK1
T14597 300-304 Protein denotes mice
R10921 T14598 T14750 themeOf TBK1,K63-polyubiquitination of TBK1 and IKKε
R10928 T14612 T14730 themeOf IRF3,IRF3 activation
R10930 T14621 T14741 themeOf IRF3,IRF3 activation
R10932 T14655 T14731 themeOf NF-κB,NF-κB activation
R10933 T14629 T14745 causeOf of different signaling proteins [80],of different signaling proteins [80]
R10934 T14640 T14742 causeOf RIG-I,RIG-I signaling
R10936 T14645 T14749 themeOf IKKε,K63-polyubiquitination of TBK1 and IKKε
R10937 T14662 T14740 causeOf A20,that A20 inhibits IAV-induced proinflammatory gene expression
R10938 T14666 T14748 themeOf TRAF3-TBK1-IKKε,disrupt the TRAF3-TBK1-IKKε
R10939 T14673 T14739 themeOf ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex,ABIN1 to to disrupt the TRAF3-TBK1-IKKε complex
R10940 T14749 T14753 themeOf K63-polyubiquitination of TBK1 and IKKε,thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε
R10941 T14750 T14754 themeOf K63-polyubiquitination of TBK1 and IKKε,thereby negatively affecting K63-polyubiquitination of TBK1 and IKKε
R10943 T14682 T14757 themeOf binding proteins,binding proteins
R10944 T14694 T14756 themeOf IKKε,"to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20"
R10945 T14695 T14759 themeOf of RIG-I,in the regulation of RIG-I induced
R10946 T14696 T14736 causeOf RIG-I,enhanced RIG-I signaling
R10947 T14697 T14733 themeOf RIG-I,RIG-I stimulation
R10948 T14699 T14732 themeOf these genes,the major pathways controlling these genes
R10949 T14701 T14598 partOf K63,TBK1
R10950 T14701 T14645 partOf K63,IKKε
R10951 T14701 T14749 siteOf K63,K63-polyubiquitination of TBK1 and IKKε
R10952 T14701 T14750 siteOf K63,K63-polyubiquitination of TBK1 and IKKε
R10953 T14702 T14746 themeOf TBK1,disrupt the TRAF3-TBK1-IKKε
R10954 T14705 T14738 causeOf RIG-I induced,RIG-I induced signaling
R10955 T14705 T14751 themeOf RIG-I induced,RIG-I induced
R10956 T14705 T14752 themeOf RIG-I induced,RIG-I induced
R10957 T14707 T14734 themeOf IRF3,"IRF3 activation,"
R10958 T14718 T14760 themeOf A20,A20 expression in myeloid cells
R10959 T14719 T14755 themeOf TBK1,"to clearly detect ubiquitination of TBK1 and IKKε in primary macrophages, preventing us from studying the effect of A20"
R10960 T14725 T14747 themeOf TRAF3,disrupt the TRAF3-TBK1-IKKε
R10961 T14736 T14735 themeOf enhanced RIG-I signaling,enhanced RIG-I signaling

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T14041 2466-2467 . denotes .
T14040 2454-2466 VBN denotes investigated
T14039 2451-2453 VB denotes be
T14038 2448-2450 TO denotes to
T14037 2440-2447 VBZ denotes remains
T14036 2438-2439 , denotes ,
T14035 2433-2438 NNS denotes cells
T14034 2422-2432 JJ denotes epithelial
T14033 2417-2421 NN denotes lung
T14032 2414-2416 IN denotes as
T14031 2409-2413 JJ denotes such
T14030 2407-2408 , denotes ,
T13843 1381-1383 PRP denotes us
T13842 1370-1380 VBG denotes preventing
T13841 1368-1369 , denotes ,
T13840 1357-1368 NNS denotes macrophages
T13839 1349-1356 JJ denotes primary
T13838 1346-1348 IN denotes in
T13837 1341-1345 NNP denotes IKKε
T13836 1337-1340 CC denotes and
T13835 1332-1336 CD denotes TBK1
T13834 1329-1331 IN denotes of
T13833 1314-1328 NN denotes ubiquitination
T13832 1307-1313 VB denotes detect
T13831 1299-1306 RB denotes clearly
T13830 1296-1298 TO denotes to
T13829 1289-1295 JJ denotes unable
T13828 1284-1288 VBD denotes were
T13827 1281-1283 PRP denotes we
T13826 1277-1280 RB denotes far
T13825 1274-1276 RB denotes So
T13824 1272-1273 . denotes .
T13823 1265-1272 JJ denotes unclear
T13822 1259-1264 RB denotes still
T13821 1256-1258 VBZ denotes is
T13820 1245-1255 NN denotes activation
T13819 1239-1244 NNP denotes NF-κB
T13818 1231-1238 VBD denotes induced
T13817 1225-1230 NNP denotes RIG-I
T13816 1222-1224 IN denotes of
T13815 1211-1221 NN denotes regulation
T13814 1207-1210 DT denotes the
T13813 1204-1206 IN denotes in
T13812 1195-1203 VBN denotes involved
T13811 1191-1194 VBP denotes are
T13810 1180-1190 NNS denotes mechanisms
T13809 1172-1179 JJ denotes similar
T13808 1164-1171 IN denotes Whether
T13807 1162-1163 . denotes .
T13806 1161-1162 NNP denotes ]
T13805 1159-1161 CD denotes 82
T13804 1158-1159 NNP denotes [
T13803 1156-1157 , denotes ,
T13802 1155-1156 NNP denotes ]
T13801 1153-1155 CD denotes 81
T13800 1152-1153 NNP denotes [
T13799 1147-1151 CD denotes IRF3
T13798 1138-1146 NN denotes activity
T13797 1135-1137 TO denotes to
T13796 1127-1134 NN denotes ability
T13795 1121-1126 PRP$ denotes their
T13794 1117-1120 CC denotes and
T13793 1115-1116 , denotes ,
T13792 1111-1115 NNP denotes IKKε
T13791 1107-1110 CC denotes and
T13790 1102-1106 CD denotes TBK1
T13789 1099-1101 IN denotes of
T13788 1076-1098 NN denotes K63-polyubiquitination
T13787 1066-1075 VBG denotes affecting
T13786 1055-1065 RB denotes negatively
T13785 1047-1054 RB denotes thereby
T13784 1045-1046 , denotes ,
T13783 1038-1045 NN denotes complex
T13782 1022-1037 NN denotes TRAF3-TBK1-IKKε
T13781 1018-1021 DT denotes the
T13780 1010-1017 VB denotes disrupt
T13779 1007-1009 TO denotes to
T13778 1004-1006 TO denotes to
T13777 998-1003 CD denotes ABIN1
T13776 994-997 CC denotes and
T13775 986-993 CD denotes TAX1BP1
T13774 977-985 NNS denotes proteins
T13773 959-976 JJ denotes ubiquitin-binding
T13772 955-958 DT denotes the
T13771 950-954 IN denotes with
T13770 939-949 NNS denotes cooperates
T13769 935-938 CD denotes A20
T13768 930-934 IN denotes that
T13767 924-929 VBN denotes shown
T13766 915-923 RB denotes recently
T13765 911-914 VBD denotes was
T13764 908-910 PRP denotes it
T13763 906-907 , denotes ,
T13762 899-906 NN denotes context
T13761 894-898 DT denotes this
T13760 891-893 IN denotes In
T13759 889-890 . denotes .
T13758 888-889 NNP denotes ]
T13757 886-888 CD denotes 80
T13756 885-886 NNP denotes [
T13755 876-884 NNS denotes proteins
T13754 866-875 VBG denotes signaling
T13753 856-865 JJ denotes different
T13752 853-855 IN denotes of
T13751 846-852 NN denotes status
T13750 831-845 NN denotes ubiquitination
T13749 827-830 DT denotes the
T13748 816-826 VBG denotes modulating
T13747 813-815 IN denotes by
T13746 803-812 NNS denotes functions
T13745 792-802 JJ denotes inhibitory
T13744 787-791 NNP denotes IRF3
T13743 783-786 CC denotes and
T13742 777-782 NNP denotes NF-κB
T13741 773-776 PRP$ denotes its
T13740 767-772 VB denotes exert
T13739 764-766 TO denotes to
T13738 755-763 VBN denotes believed
T13737 752-754 VBZ denotes is
T13736 748-751 CD denotes A20
T13735 746-747 . denotes .
T13734 736-746 NN denotes expression
T13733 731-735 NN denotes gene
T13732 715-730 JJ denotes proinflammatory
T13731 712-714 TO denotes to
T13730 701-711 VB denotes contribute
T13729 697-700 MD denotes may
T13728 692-696 WDT denotes that
T13727 683-691 NNS denotes pathways
T13726 673-682 VBG denotes signaling
T13725 667-672 JJ denotes other
T13724 664-666 IN denotes on
T13723 660-663 NNP denotes A20
T13722 657-659 IN denotes of
T13721 650-656 NN denotes effect
T13720 639-649 JJ denotes additional
T13719 636-638 DT denotes an
T13718 628-635 VB denotes exclude
T13717 624-627 RB denotes not
T13716 619-623 VBZ denotes does
T13715 614-618 DT denotes this
T13714 612-613 , denotes ,
T13713 605-612 RB denotes However
T13712 603-604 . denotes .
T13711 598-603 NNS denotes genes
T13710 592-597 DT denotes these
T13709 580-591 VBG denotes controlling
T13708 571-579 NNS denotes pathways
T13707 565-570 JJ denotes major
T13706 561-564 DT denotes the
T13705 557-560 VBP denotes are
T13704 551-556 WDT denotes which
T13703 549-550 , denotes ,
T13702 539-549 NN denotes activation
T13701 534-538 NNP denotes IRF3
T13700 530-533 CC denotes and
T13699 524-529 NNP denotes NF-κB
T13698 513-523 VBG denotes regulating
T13697 502-512 RB denotes negatively
T13696 499-501 IN denotes by
T13695 497-498 -RRB- denotes )
T13694 493-497 NNP denotes IFNβ
T13693 489-492 CC denotes and
T13692 487-488 , denotes ,
T13691 482-487 NNP denotes MIP-2
T13690 480-481 , denotes ,
T13689 478-480 NNP denotes KC
T13688 476-477 , denotes ,
T13687 472-476 NNP denotes IL-6
T13686 470-471 , denotes ,
T13685 467-470 NNP denotes TNF
T13684 463-466 IN denotes for
T13683 452-462 NN denotes manuscript
T13682 448-451 PRP$ denotes our
T13681 445-447 IN denotes in
T13680 439-444 VBN denotes shown
T13679 436-438 IN denotes as
T13678 435-436 -LRB- denotes (
T13677 424-434 NN denotes expression
T13676 419-423 NN denotes gene
T13675 403-418 JJ denotes proinflammatory
T13674 391-402 JJ denotes IAV-induced
T13673 382-390 NNS denotes inhibits
T13672 378-381 CD denotes A20
T13671 373-377 IN denotes that
T13670 365-372 VBP denotes propose
T13669 362-364 PRP denotes We
T13668 360-361 . denotes .
T13667 351-360 VBG denotes signaling
T13666 345-350 NNP denotes RIG-I
T13665 336-344 JJ denotes enhanced
T13664 327-335 VBZ denotes reflects
T13663 317-326 NN denotes infection
T13662 312-316 NN denotes lung
T13661 308-311 NNP denotes IAV
T13660 305-307 TO denotes to
T13659 300-304 NNS denotes mice
T13658 289-299 JJ denotes A20myel-KO
T13657 286-288 IN denotes of
T13656 277-285 NN denotes response
T13655 270-276 JJ denotes immune
T13654 260-269 VBN denotes increased
T13653 256-259 DT denotes the
T13652 251-255 IN denotes that
T13651 240-250 VBG denotes suggesting
T13650 238-239 , denotes ,
T13649 237-238 NNP denotes ]
T13648 235-237 CD denotes 13
T13647 234-235 NNP denotes [
T13646 230-233 NNP denotes IAV
T13645 227-229 TO denotes to
T13644 218-226 NN denotes response
T13643 211-217 JJ denotes immune
T13642 204-210 NN denotes innate
T13641 200-203 DT denotes the
T13640 197-199 IN denotes in
T13639 192-196 NN denotes role
T13638 188-191 JJ denotes key
T13637 186-187 DT denotes a
T13636 181-185 VB denotes play
T13635 178-180 TO denotes to
T13634 172-177 VBN denotes shown
T13633 167-171 VBN denotes been
T13632 156-166 RB denotes previously
T13631 152-155 VBZ denotes has
T13630 146-151 NNP denotes RIG-I
T13629 144-145 . denotes .
T13628 141-144 NNP denotes RNA
T14029 2404-2407 NNP denotes IAV
T14028 2401-2403 TO denotes to
T14027 2392-2400 NN denotes response
T14026 2388-2391 DT denotes the
T14025 2385-2387 IN denotes in
T14024 2374-2384 VBN denotes implicated
T14023 2370-2373 VBP denotes are
T14022 2365-2369 WDT denotes that
T14021 2359-2364 NNS denotes types
T14020 2354-2358 NN denotes cell
T14019 2348-2353 JJ denotes other
T14018 2345-2347 IN denotes in
T14017 2340-2344 NN denotes role
T14016 2326-2339 JJ denotes non-redundant
T14015 2318-2325 JJ denotes similar
T14014 2316-2317 DT denotes a
T14013 2312-2315 VBZ denotes has
T14012 2308-2311 NNP denotes A20
T14011 2305-2307 IN denotes If
T14010 2303-2304 . denotes .
T14009 2293-2303 NNS denotes conditions
T14008 2279-2292 JJ denotes physiological
T14007 2273-2278 IN denotes under
T14006 2262-2272 NN denotes deficiency
T14005 2258-2261 NNP denotes A20
T14004 2254-2257 IN denotes for
T14003 2243-2253 VB denotes substitute
T14002 2239-2242 RB denotes not
T14001 2236-2239 MD denotes can
T14000 2231-2235 NNS denotes DUBs
T13999 2225-2230 JJ denotes other
T13998 2220-2224 IN denotes that
T13997 2216-2219 CC denotes and
T13996 2206-2215 NN denotes infection
T13995 2202-2205 NNP denotes IAV
T13994 2199-2201 TO denotes to
T13993 2190-2198 NN denotes response
T13992 2187-2189 IN denotes in
T13991 2177-2186 VBG denotes signaling
T13990 2169-2176 VBD denotes induced
T13989 2163-2168 NNP denotes RIG-I
T13988 2160-2162 IN denotes of
T13987 2149-2159 NN denotes gatekeeper
T13986 2141-2148 JJ denotes central
T13985 2139-2140 DT denotes a
T13984 2136-2138 VBZ denotes is
T13983 2130-2135 NNS denotes cells
T13982 2122-2129 JJ denotes myeloid
T13981 2119-2121 IN denotes in
T13980 2108-2118 NN denotes expression
T13979 2104-2107 NNP denotes A20
T13978 2099-2103 IN denotes that
T13977 2089-2098 VBZ denotes indicates
T13976 2080-2088 VBP denotes describe
T13975 2075-2079 RB denotes here
T13974 2072-2074 PRP denotes we
T13973 2067-2071 IN denotes that
T13972 2062-2066 NNS denotes mice
T13971 2051-2061 JJ denotes A20myel-KO
T13970 2048-2050 IN denotes of
T13969 2038-2047 NN denotes phenotype
T13968 2027-2037 JJ denotes protective
T13967 2021-2026 JJ denotes clear
T13966 2017-2020 DT denotes The
T13965 2015-2016 . denotes .
T13964 2005-2015 NNS denotes conditions
T13963 1987-2004 JJ denotes non-physiological
T13962 1981-1986 IN denotes under
T13961 1972-1980 VBN denotes obtained
T13960 1968-1971 VBD denotes was
T13959 1964-1967 CC denotes and
T13958 1959-1963 NNS denotes data
T13957 1953-1958 NN denotes vitro
T13956 1950-1952 IN denotes in
T13955 1947-1949 TO denotes to
T13954 1939-1946 VBN denotes limited
T13953 1935-1938 VBD denotes was
T13952 1931-1934 RB denotes far
T13951 1928-1930 RB denotes so
T13950 1919-1927 NN denotes evidence
T13949 1917-1918 , denotes ,
T13948 1910-1917 RB denotes However
T13947 1908-1909 . denotes .
T13946 1898-1908 NN denotes redundancy
T13945 1889-1897 JJ denotes possible
T13944 1877-1888 VBG denotes implicating
T13943 1875-1876 , denotes ,
T13942 1870-1875 NNP denotes IRF-3
T13941 1866-1869 CC denotes and
T13940 1860-1865 NNP denotes NF-κB
T13939 1857-1859 TO denotes to
T13938 1847-1856 VBG denotes signaling
T13937 1841-1846 NNP denotes RIG-I
T13936 1832-1840 VB denotes regulate
T13935 1821-1831 RB denotes negatively
T13934 1818-1820 TO denotes to
T13933 1812-1817 VBN denotes shown
T13932 1807-1811 VBN denotes been
T13931 1802-1806 VBP denotes have
T13930 1800-1801 NNP denotes ]
T13929 1798-1800 CD denotes 52
T13928 1797-1798 NNP denotes [
T13927 1795-1796 NNP denotes ]
T13926 1793-1795 CD denotes 49
T13925 1792-1793 NNP denotes [
T13924 1788-1791 NNP denotes A20
T13923 1784-1787 CC denotes and
T13922 1782-1783 , denotes ,
T13921 1781-1782 NNP denotes ]
T13920 1779-1781 CD denotes 31
T13919 1778-1779 NNP denotes [
T13918 1770-1777 NNP denotes OTUB1/2
T13917 1768-1769 , denotes ,
T13916 1767-1768 NNP denotes ]
T13915 1765-1767 CD denotes 30
T13914 1764-1765 NNP denotes [
T13913 1762-1763 , denotes ,
T13912 1761-1762 NNP denotes ]
T13911 1759-1761 CD denotes 29
T13910 1758-1759 NNP denotes [
T13909 1753-1757 NNP denotes CYLD
T13908 1751-1752 , denotes ,
T13907 1750-1751 NNP denotes ]
T13906 1748-1750 CD denotes 28
T13905 1747-1748 NNP denotes [
T13904 1742-1746 NNP denotes DUBA
T13903 1739-1741 IN denotes as
T13902 1734-1738 JJ denotes such
T13901 1732-1733 , denotes ,
T13900 1731-1732 -RRB- denotes )
T13899 1727-1731 NNS denotes DUBs
T13898 1726-1727 -LRB- denotes (
T13897 1718-1725 NNS denotes enzymes
T13896 1701-1717 VBG denotes deubiquitinating
T13895 1695-1700 JJ denotes other
T13894 1686-1694 JJ denotes Multiple
T13893 1684-1685 . denotes .
T13892 1674-1684 NN denotes laboratory
T13891 1670-1673 PRP$ denotes our
T13890 1667-1669 IN denotes in
T13889 1652-1666 NNS denotes investigations
T13888 1645-1651 JJ denotes future
T13887 1642-1644 IN denotes of
T13886 1636-1641 NN denotes topic
T13885 1632-1635 DT denotes the
T13884 1629-1631 VB denotes be
T13883 1624-1628 MD denotes will
T13882 1613-1623 NNS denotes substrates
T13881 1607-1612 DT denotes these
T13880 1604-1606 IN denotes of
T13879 1589-1603 NN denotes identification
T13878 1585-1588 DT denotes The
T13877 1583-1584 . denotes .
T13876 1578-1583 NNS denotes cells
T13875 1570-1577 JJ denotes myeloid
T13874 1567-1569 IN denotes in
T13873 1556-1566 NN denotes activation
T13872 1551-1555 NNP denotes IRF3
T13871 1547-1550 CC denotes and
T13870 1541-1546 NNP denotes NF-κB
T13869 1533-1540 VBP denotes mediate
T13868 1528-1532 WDT denotes that
T13867 1517-1527 NNS denotes substrates
T13866 1511-1516 JJ denotes other
T13865 1503-1510 VBZ denotes targets
T13864 1498-1502 RB denotes also
T13863 1494-1497 NNP denotes A20
T13862 1489-1493 IN denotes that
T13861 1481-1488 RB denotes however
T13860 1472-1480 VBN denotes excluded
T13859 1469-1471 VB denotes be
T13858 1465-1468 RB denotes not
T13857 1462-1465 MD denotes can
T13856 1459-1461 PRP denotes It
T13855 1457-1458 . denotes .
T13854 1451-1457 NN denotes status
T13853 1436-1450 NN denotes ubiquitination
T13852 1430-1435 PRP$ denotes their
T13851 1427-1429 IN denotes on
T13850 1416-1426 NN denotes deficiency
T13849 1412-1415 NNP denotes A20
T13848 1409-1411 IN denotes of
T13847 1402-1408 NN denotes effect
T13846 1398-1401 DT denotes the
T13845 1389-1397 VBG denotes studying
T13844 1384-1388 IN denotes from
T13627 132-140 VBD denotes stranded
T13626 125-131 JJ denotes double
T13625 121-124 NNP denotes LMW
T13624 111-120 JJ denotes synthetic
T13623 108-110 IN denotes by
T13622 96-107 NN denotes stimulation
T13621 90-95 NNP denotes RIG-I
T13620 87-89 TO denotes to
T13619 78-86 NN denotes response
T13618 75-77 IN denotes in
T13617 64-74 NN denotes activation
T13616 59-63 NNP denotes IRF3
T13615 55-58 CC denotes and
T13614 49-54 NNP denotes NF-κB
T13613 40-48 VBN denotes enhanced
T13612 32-39 NN denotes display
T13611 27-31 NNP denotes BMDM
T13610 17-26 JJ denotes deficient
T13609 13-16 CD denotes A20
T13608 8-12 IN denotes that
T13607 3-7 VBP denotes show
T13606 0-2 PRP denotes We
R10169 T13606 T13607 nsubj We,show
R10170 T13607 T13607 ROOT show,show
R10171 T13608 T13613 mark that,enhanced
R10172 T13609 T13612 nummod A20,display
R10173 T13610 T13612 amod deficient,display
R10174 T13611 T13612 compound BMDM,display
R10175 T13612 T13613 nsubj display,enhanced
R10176 T13613 T13607 ccomp enhanced,show
R10177 T13614 T13613 dobj NF-κB,enhanced
R10178 T13615 T13614 cc and,NF-κB
R10179 T13616 T13614 conj IRF3,NF-κB
R10180 T13617 T13627 nsubj activation,stranded
R10181 T13618 T13617 prep in,activation
R10182 T13619 T13618 pobj response,in
R10183 T13620 T13619 prep to,response
R10184 T13621 T13622 compound RIG-I,stimulation
R10185 T13622 T13620 pobj stimulation,to
R10186 T13623 T13622 prep by,stimulation
R10187 T13624 T13626 amod synthetic,double
R10188 T13625 T13626 compound LMW,double
R10189 T13626 T13623 pobj double,by
R10190 T13627 T13613 conj stranded,enhanced
R10191 T13628 T13627 dobj RNA,stranded
R10192 T13629 T13607 punct .,show
R10193 T13630 T13634 nsubj RIG-I,shown
R10194 T13631 T13634 aux has,shown
R10195 T13632 T13634 advmod previously,shown
R10196 T13633 T13634 auxpass been,shown
R10197 T13634 T13634 ROOT shown,shown
R10198 T13635 T13636 aux to,play
R10199 T13636 T13634 xcomp play,shown
R10200 T13637 T13639 det a,role
R10201 T13638 T13639 amod key,role
R10202 T13639 T13636 dobj role,play
R10203 T13640 T13636 prep in,play
R10204 T13641 T13644 det the,response
R10205 T13642 T13644 amod innate,response
R10206 T13643 T13644 amod immune,response
R10207 T13644 T13640 pobj response,in
R10208 T13645 T13644 prep to,response
R10209 T13646 T13647 compound IAV,[
R10210 T13647 T13645 pobj [,to
R10211 T13648 T13649 nummod 13,]
R10212 T13649 T13649 ROOT ],]
R10213 T13650 T13634 punct ",",shown
R10214 T13651 T13634 advcl suggesting,shown
R10215 T13652 T13664 mark that,reflects
R10216 T13653 T13656 det the,response
R10217 T13654 T13656 amod increased,response
R10219 T13656 T13664 nsubj response,reflects
R10220 T13657 T13656 prep of,response
R10221 T13658 T13659 amod A20myel-KO,mice
R10222 T13659 T13657 pobj mice,of
R10223 T13660 T13656 prep to,response
R10224 T13661 T13663 compound IAV,infection
R10225 T13662 T13663 compound lung,infection
R10226 T13663 T13660 pobj infection,to
R10227 T13664 T13651 ccomp reflects,suggesting
R10228 T13665 T13667 amod enhanced,signaling
R10229 T13666 T13667 compound RIG-I,signaling
R10230 T13667 T13664 dobj signaling,reflects
R10231 T13668 T13634 punct .,shown
R10232 T13669 T13670 nsubj We,propose
R10233 T13670 T13670 ROOT propose,propose
R10234 T13671 T13673 mark that,inhibits
R10235 T13672 T13673 nummod A20,inhibits
R10236 T13673 T13670 ccomp inhibits,propose
R10237 T13674 T13677 nmod IAV-induced,expression
R10238 T13675 T13677 amod proinflammatory,expression
R10239 T13676 T13677 compound gene,expression
R10240 T13677 T13673 dobj expression,inhibits
R10241 T13678 T13680 punct (,shown
R10242 T13679 T13680 mark as,shown
R10243 T13680 T13677 advcl shown,expression
R10244 T13681 T13680 prep in,shown
R10245 T13682 T13683 poss our,manuscript
R10246 T13683 T13681 pobj manuscript,in
R10247 T13684 T13683 prep for,manuscript
R10248 T13685 T13684 pobj TNF,for
R10249 T13686 T13685 punct ",",TNF
R10250 T13687 T13685 conj IL-6,TNF
R10251 T13688 T13687 punct ",",IL-6
R10252 T13689 T13687 conj KC,IL-6
R10253 T13690 T13689 punct ",",KC
R10254 T13691 T13689 conj MIP-2,KC
R10255 T13692 T13691 punct ",",MIP-2
R10256 T13693 T13691 cc and,MIP-2
R10257 T13694 T13691 conj IFNβ,MIP-2
R10258 T13695 T13680 punct ),shown
R10259 T13696 T13673 prep by,inhibits
R10260 T13697 T13698 advmod negatively,regulating
R10261 T13698 T13696 pcomp regulating,by
R10262 T13699 T13698 dobj NF-κB,regulating
R10263 T13700 T13699 cc and,NF-κB
R10264 T13701 T13702 compound IRF3,activation
R10265 T13702 T13699 conj activation,NF-κB
R10266 T13703 T13698 punct ",",regulating
R10267 T13704 T13705 nsubj which,are
R10268 T13705 T13673 relcl are,inhibits
R10269 T13706 T13708 det the,pathways
R10270 T13707 T13708 amod major,pathways
R10271 T13708 T13705 attr pathways,are
R10272 T13709 T13708 acl controlling,pathways
R10273 T13710 T13711 det these,genes
R10274 T13711 T13709 dobj genes,controlling
R10275 T13712 T13670 punct .,propose
R10276 T13713 T13718 advmod However,exclude
R10277 T13714 T13718 punct ",",exclude
R10278 T13715 T13718 nsubj this,exclude
R10279 T13716 T13718 aux does,exclude
R10280 T13717 T13718 neg not,exclude
R10281 T13718 T13718 ROOT exclude,exclude
R10282 T13719 T13721 det an,effect
R10283 T13720 T13721 amod additional,effect
R10284 T13721 T13718 dobj effect,exclude
R10285 T13722 T13721 prep of,effect
R10286 T13723 T13722 pobj A20,of
R10287 T13724 T13721 prep on,effect
R10288 T13725 T13727 amod other,pathways
R10289 T13726 T13727 amod signaling,pathways
R10290 T13727 T13724 pobj pathways,on
R10291 T13728 T13730 nsubj that,contribute
R10296 T13733 T13734 compound gene,expression
R10297 T13734 T13731 pobj expression,to
R10298 T13735 T13718 punct .,exclude
R10299 T13736 T13738 nsubjpass A20,believed
R10300 T13737 T13738 auxpass is,believed
R10301 T13738 T13738 ROOT believed,believed
R10302 T13739 T13740 aux to,exert
R10303 T13740 T13738 xcomp exert,believed
R10304 T13741 T13746 poss its,functions
R10305 T13742 T13746 nmod NF-κB,functions
R10306 T13743 T13742 cc and,NF-κB
R10307 T13744 T13742 conj IRF3,NF-κB
R10308 T13745 T13746 amod inhibitory,functions
R10309 T13746 T13740 dobj functions,exert
R10310 T13747 T13740 prep by,exert
R10311 T13748 T13747 pcomp modulating,by
R10312 T13749 T13751 det the,status
R10313 T13750 T13751 amod ubiquitination,status
R10314 T13751 T13748 dobj status,modulating
R10315 T13752 T13751 prep of,status
R10316 T13753 T13755 amod different,proteins
R10317 T13754 T13755 compound signaling,proteins
R10318 T13755 T13752 pobj proteins,of
R10319 T13756 T13758 nmod [,]
R10320 T13757 T13758 nummod 80,]
R10321 T13758 T13751 appos ],status
R10322 T13759 T13738 punct .,believed
R10323 T13760 T13767 prep In,shown
R10324 T13761 T13762 det this,context
R10325 T13762 T13760 pobj context,In
R10326 T13763 T13767 punct ",",shown
R10327 T13764 T13767 nsubjpass it,shown
R10328 T13765 T13767 auxpass was,shown
R10329 T13766 T13767 advmod recently,shown
R10330 T13767 T13767 ROOT shown,shown
R10331 T13768 T13767 dobj that,shown
R10332 T13769 T13770 nummod A20,cooperates
R10333 T13770 T13768 advmod cooperates,that
R10334 T13771 T13770 prep with,cooperates
R10335 T13772 T13774 det the,proteins
R10336 T13773 T13774 amod ubiquitin-binding,proteins
R10337 T13774 T13771 pobj proteins,with
R10338 T13775 T13774 appos TAX1BP1,proteins
R10339 T13776 T13775 cc and,TAX1BP1
R10340 T13777 T13775 conj ABIN1,TAX1BP1
R10341 T13778 T13780 aux to,disrupt
R10342 T13779 T13780 aux to,disrupt
R10343 T13780 T13770 xcomp disrupt,cooperates
R10344 T13781 T13783 det the,complex
R10345 T13782 T13783 compound TRAF3-TBK1-IKKε,complex
R10346 T13783 T13780 dobj complex,disrupt
R10347 T13784 T13770 punct ",",cooperates
R10348 T13785 T13787 advmod thereby,affecting
R10349 T13786 T13787 advmod negatively,affecting
R10350 T13787 T13770 conj affecting,cooperates
R10351 T13788 T13787 dobj K63-polyubiquitination,affecting
R10352 T13789 T13788 prep of,K63-polyubiquitination
R10353 T13790 T13789 pobj TBK1,of
R10354 T13791 T13790 cc and,TBK1
R10355 T13792 T13790 conj IKKε,TBK1
R10356 T13793 T13792 punct ",",IKKε
R10357 T13794 T13792 cc and,IKKε
R10358 T13795 T13796 poss their,ability
R10359 T13796 T13787 dobj ability,affecting
R10360 T13797 T13798 aux to,activity
R10361 T13798 T13787 advcl activity,affecting
R10362 T13799 T13802 nummod IRF3,]
R10363 T13800 T13802 nmod [,]
R10364 T13801 T13802 nummod 81,]
R10365 T13802 T13798 dobj ],activity
R10366 T13803 T13802 punct ",",]
R10367 T13804 T13802 conj [,]
R10368 T13805 T13806 nummod 82,]
R10369 T13806 T13802 conj ],]
R10370 T13807 T13767 punct .,shown
R10371 T13808 T13812 mark Whether,involved
R10372 T13809 T13810 amod similar,mechanisms
R10373 T13810 T13812 nsubjpass mechanisms,involved
R10374 T13811 T13812 auxpass are,involved
R10375 T13812 T13821 advcl involved,is
R10376 T13813 T13812 prep in,involved
R10377 T13814 T13815 det the,regulation
R10378 T13815 T13813 pobj regulation,in
R10379 T13816 T13815 prep of,regulation
R10380 T13817 T13816 pobj RIG-I,of
R10381 T13818 T13820 amod induced,activation
R10382 T13819 T13820 compound NF-κB,activation
R10383 T13820 T13821 nsubj activation,is
R10384 T13821 T13821 ROOT is,is
R10385 T13822 T13821 advmod still,is
R10386 T13823 T13821 acomp unclear,is
R10387 T13824 T13821 punct .,is
R10388 T13825 T13826 advmod So,far
R10389 T13826 T13828 advmod far,were
R10390 T13827 T13828 nsubj we,were
R10391 T13828 T13828 ROOT were,were
R10392 T13829 T13828 acomp unable,were
R10393 T13830 T13832 aux to,detect
R10394 T13831 T13832 advmod clearly,detect
R10395 T13832 T13829 xcomp detect,unable
R10396 T13833 T13832 dobj ubiquitination,detect
R10397 T13834 T13833 prep of,ubiquitination
R10398 T13835 T13834 pobj TBK1,of
R10399 T13836 T13835 cc and,TBK1
R10400 T13837 T13833 conj IKKε,ubiquitination
R10401 T13838 T13837 prep in,IKKε
R10402 T13839 T13840 amod primary,macrophages
R10403 T13840 T13838 pobj macrophages,in
R10404 T13841 T13828 punct ",",were
R10405 T13842 T13828 advcl preventing,were
R10406 T13843 T13842 dobj us,preventing
R10407 T13844 T13842 prep from,preventing
R10408 T13845 T13844 pcomp studying,from
R10409 T13846 T13847 det the,effect
R10410 T13847 T13845 dobj effect,studying
R10411 T13848 T13847 prep of,effect
R10412 T13849 T13850 compound A20,deficiency
R10413 T13850 T13848 pobj deficiency,of
R10414 T13851 T13845 prep on,studying
R10415 T13852 T13854 poss their,status
R10416 T13853 T13854 compound ubiquitination,status
R10417 T13951 T13952 advmod so,far
R10418 T13952 T13954 advmod far,limited
R10419 T13953 T13954 auxpass was,limited
R10420 T13954 T13954 ROOT limited,limited
R10421 T13955 T13954 prep to,limited
R10422 T13956 T13954 prep in,limited
R10423 T13957 T13958 amod vitro,data
R10424 T13958 T13956 pobj data,in
R10425 T13959 T13954 cc and,limited
R10426 T13960 T13961 auxpass was,obtained
R10427 T13961 T13954 conj obtained,limited
R10428 T13962 T13961 prep under,obtained
R10429 T13963 T13964 amod non-physiological,conditions
R10430 T13964 T13962 pobj conditions,under
R10431 T13854 T13851 pobj status,on
R10432 T13965 T13954 punct .,limited
R10433 T13855 T13828 punct .,were
R10434 T13856 T13860 nsubjpass It,excluded
R10435 T13857 T13860 aux can,excluded
R10436 T13966 T13969 det The,phenotype
R10437 T13858 T13860 neg not,excluded
R10438 T13859 T13860 auxpass be,excluded
R10439 T13967 T13969 amod clear,phenotype
R10440 T13860 T13860 ROOT excluded,excluded
R10441 T13861 T13860 advmod however,excluded
R10442 T13862 T13865 mark that,targets
R10443 T13968 T13969 amod protective,phenotype
R10444 T13863 T13865 nsubj A20,targets
R10445 T13864 T13865 advmod also,targets
R10446 T13969 T13977 nsubj phenotype,indicates
R10447 T13865 T13860 ccomp targets,excluded
R10448 T13866 T13867 amod other,substrates
R10449 T13867 T13865 dobj substrates,targets
R10450 T13970 T13969 prep of,phenotype
R10451 T13868 T13869 nsubj that,mediate
R10452 T13869 T13867 relcl mediate,substrates
R10453 T13971 T13972 amod A20myel-KO,mice
R10454 T13870 T13869 dobj NF-κB,mediate
R10455 T13871 T13870 cc and,NF-κB
R10456 T13872 T13870 conj IRF3,NF-κB
R10457 T13873 T13869 dobj activation,mediate
R10458 T13972 T13970 pobj mice,of
R10459 T13874 T13873 prep in,activation
R10460 T13875 T13876 amod myeloid,cells
R10461 T13876 T13874 pobj cells,in
R10462 T13973 T13976 dobj that,describe
R10463 T13877 T13860 punct .,excluded
R10464 T13878 T13879 det The,identification
R10465 T13879 T13884 nsubj identification,be
R10466 T13974 T13976 nsubj we,describe
R10467 T13880 T13879 prep of,identification
R10468 T13881 T13882 det these,substrates
R10469 T13975 T13976 advmod here,describe
R10470 T13882 T13880 pobj substrates,of
R10471 T13883 T13884 aux will,be
R10472 T13884 T13884 ROOT be,be
R10473 T13885 T13886 det the,topic
R10474 T13976 T13972 relcl describe,mice
R10475 T13886 T13884 attr topic,be
R10476 T13977 T13977 ROOT indicates,indicates
R10477 T13978 T13984 mark that,is
R10480 T13979 T13980 compound A20,expression
R10486 T13980 T13984 nsubj expression,is
R10487 T13981 T13980 prep in,expression
R10488 T13894 T13897 amod Multiple,enzymes
R10489 T13895 T13897 amod other,enzymes
R10490 T13982 T13983 amod myeloid,cells
R10491 T13896 T13897 amod deubiquitinating,enzymes
R10492 T13897 T13933 nsubjpass enzymes,shown
R10493 T13898 T13899 punct (,DUBs
R10494 T13983 T13981 pobj cells,in
R10495 T13899 T13897 appos DUBs,enzymes
R10496 T13900 T13897 punct ),enzymes
R10497 T13901 T13897 punct ",",enzymes
R10498 T13984 T13977 ccomp is,indicates
R10499 T13902 T13903 amod such,as
R10500 T13903 T13897 prep as,enzymes
R10501 T13985 T13987 det a,gatekeeper
R10502 T13904 T13905 compound DUBA,[
R10503 T13905 T13903 pobj [,as
R10504 T13986 T13987 amod central,gatekeeper
R10505 T13906 T13907 compound 28,]
R10506 T13907 T13905 conj ],[
R10507 T13908 T13907 punct ",",]
R10508 T13987 T13984 attr gatekeeper,is
R10509 T13909 T13910 compound CYLD,[
R10510 T13910 T13907 conj [,]
R10511 T13911 T13912 compound 29,]
R10512 T13912 T13907 conj ],]
R10513 T13988 T13987 prep of,gatekeeper
R10514 T13913 T13912 punct ",",]
R10515 T13914 T13912 conj [,]
R10516 T13915 T13916 nummod 30,]
R10517 T13989 T13988 pobj RIG-I,of
R10518 T13916 T13912 conj ],]
R10519 T13917 T13916 punct ",",]
R10520 T13918 T13919 compound OTUB1/2,[
R10521 T13990 T13987 acl induced,gatekeeper
R10522 T13919 T13916 conj [,]
R10523 T13920 T13921 nummod 31,]
R10524 T13991 T13990 xcomp signaling,induced
R10525 T13921 T13928 nmod ],[
R10526 T13922 T13921 punct ",",]
R10527 T13923 T13921 cc and,]
R10528 T13992 T13991 prep in,signaling
R10529 T13924 T13925 compound A20,[
R10530 T13925 T13921 conj [,]
R10531 T13993 T13992 pobj response,in
R10532 T13926 T13927 nummod 49,]
R10533 T13927 T13928 nmod ],[
R10534 T13928 T13930 det [,]
R10535 T13929 T13930 nummod 52,]
R10536 T13930 T13916 conj ],]
R10537 T13931 T13933 aux have,shown
R10538 T13994 T13993 prep to,response
R10539 T13932 T13933 auxpass been,shown
R10540 T13933 T13933 ROOT shown,shown
R10541 T13934 T13936 aux to,regulate
R10542 T13995 T13996 compound IAV,infection
R10543 T13935 T13936 advmod negatively,regulate
R10544 T13936 T13933 xcomp regulate,shown
R10545 T13937 T13938 nsubj RIG-I,signaling
R10546 T13996 T13994 pobj infection,to
R10547 T13938 T13936 ccomp signaling,regulate
R10548 T13939 T13938 prep to,signaling
R10549 T13940 T13939 pobj NF-κB,to
R10550 T13997 T13990 cc and,induced
R10551 T13941 T13940 cc and,NF-κB
R10552 T13942 T13940 conj IRF-3,NF-κB
R10553 T13943 T13938 punct ",",signaling
R10554 T13998 T14003 mark that,substitute
R10555 T13944 T13933 advcl implicating,shown
R10556 T13945 T13946 amod possible,redundancy
R10557 T13999 T14000 amod other,DUBs
R10558 T13946 T13944 dobj redundancy,implicating
R10559 T13947 T13933 punct .,shown
R10560 T13948 T13954 advmod However,limited
R10561 T14000 T14003 nsubj DUBs,substitute
R10562 T13949 T13954 punct ",",limited
R10563 T13950 T13954 nsubjpass evidence,limited
R10564 T14001 T14003 aux can,substitute
R10565 T14002 T14003 neg not,substitute
R10566 T14003 T13990 conj substitute,induced
R10567 T14004 T14003 prep for,substitute
R10568 T14005 T14006 compound A20,deficiency
R10571 T14006 T14004 pobj deficiency,for
R10573 T14007 T14003 prep under,substitute
R10574 T14008 T14009 amod physiological,conditions
R10577 T14009 T14007 pobj conditions,under
R10580 T14010 T13977 punct .,indicates
R10586 T14011 T14013 mark If,has
R10590 T14012 T14013 nsubj A20,has
R10593 T14013 T14037 advcl has,remains
R10598 T14014 T14017 det a,role
R10601 T14015 T14017 amod similar,role
R10605 T14016 T14017 amod non-redundant,role
R10606 T14017 T14013 dobj role,has
R10607 T14018 T14017 prep in,role
R10609 T14019 T14021 amod other,types
R10611 T14020 T14021 compound cell,types
R10615 T14021 T14018 pobj types,in
R10619 T14022 T14024 nsubjpass that,implicated
R10623 T14023 T14024 auxpass are,implicated
R10627 T14024 T14021 relcl implicated,types
R10631 T14025 T14024 prep in,implicated
R10637 T14026 T14027 det the,response
R10641 T14027 T14025 pobj response,in
R10645 T14028 T14027 prep to,response
R10649 T14029 T14028 pobj IAV,to
R10653 T14030 T14027 punct ",",response
R10657 T14031 T14032 amod such,as
R10662 T14032 T14027 prep as,response
R10666 T14033 T14035 nmod lung,cells
R10670 T14034 T14035 amod epithelial,cells
R10673 T14035 T14032 pobj cells,as
R10674 T14036 T14037 punct ",",remains
R10677 T14037 T14037 ROOT remains,remains
R10681 T14038 T14040 aux to,investigated
R10683 T14039 T14040 auxpass be,investigated
R10688 T14040 T14037 xcomp investigated,remains
R10693 T14041 T14037 punct .,remains
R10218 T13655 T13656 amod immune,response
R10292 T13729 T13730 aux may,contribute
R10293 T13730 T13727 relcl contribute,pathways
R10294 T13731 T13730 prep to,contribute
R10295 T13732 T13734 amod proinflammatory,expression
R10478 T13887 T13886 prep of,topic
R10479 T13888 T13889 amod future,investigations
R10481 T13889 T13887 pobj investigations,of
R10482 T13890 T13889 prep in,investigations
R10483 T13891 T13892 poss our,laboratory
R10484 T13892 T13890 pobj laboratory,in
R10485 T13893 T13884 punct .,be

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T14486 2308-2311 Protein denotes A20
T14485 2108-2118 Gene_expression denotes expression
T14484 2163-2168 Protein denotes RIG-I
T14483 2104-2107 Protein denotes A20
T14482 1870-1875 Protein denotes IRF-3
T14481 1860-1865 Protein denotes NF-κB
T14480 1841-1846 Protein denotes RIG-I
T14479 1533-1540 Positive_regulation denotes mediate
T14478 1533-1540 Positive_regulation denotes mediate
T14477 1556-1566 Positive_regulation denotes activation
T14476 1556-1566 Positive_regulation denotes activation
T14475 1551-1555 Protein denotes IRF3
T14474 1541-1546 Protein denotes NF-κB
T14473 1494-1497 Protein denotes A20
T14472 1416-1426 Negative_regulation denotes deficiency
T14471 1412-1415 Protein denotes A20
T14470 1332-1345 Protein denotes TBK1 and IKKε
T14469 1239-1244 Protein denotes NF-κB
T14468 1225-1230 Protein denotes RIG-I
T14467 969-976 Binding denotes binding
T14466 1102-1106 Protein denotes TBK1
T14465 1028-1032 Protein denotes TBK1
T14464 1022-1027 Protein denotes TRAF3
T14463 998-1003 Protein denotes ABIN1
T14462 986-993 Protein denotes TAX1BP1
T14461 959-968 Protein denotes ubiquitin
T14460 787-791 Protein denotes IRF3
T14459 777-782 Protein denotes NF-κB
T14458 748-751 Protein denotes A20
T14457 382-390 Negative_regulation denotes inhibits
T14456 382-390 Negative_regulation denotes inhibits
T14455 539-549 Positive_regulation denotes activation
T14454 539-549 Positive_regulation denotes activation
T14453 534-538 Protein denotes IRF3
T14452 524-529 Protein denotes NF-κB
T14451 493-497 Protein denotes IFNβ
T14450 482-487 Protein denotes MIP-2
T14449 478-480 Protein denotes KC
T14448 472-476 Protein denotes IL-6
T14447 467-470 Protein denotes TNF
T14446 345-350 Protein denotes RIG-I
T14445 40-48 Positive_regulation denotes enhanced
T14444 40-48 Positive_regulation denotes enhanced
T14443 64-74 Positive_regulation denotes activation
T14442 64-74 Positive_regulation denotes activation
T14441 90-95 Protein denotes RIG-I
T14440 59-63 Protein denotes IRF3
T14439 49-54 Protein denotes NF-κB
R10876 T14439 T14442 themeOf NF-κB,activation
R10877 T14440 T14443 themeOf IRF3,activation
R10878 T14442 T14444 themeOf activation,enhanced
R10879 T14443 T14445 themeOf activation,enhanced
R10880 T14452 T14454 themeOf NF-κB,activation
R10883 T14453 T14455 themeOf IRF3,activation
R10885 T14454 T14456 themeOf activation,inhibits
R10886 T14455 T14457 themeOf activation,inhibits
R10887 T14461 T14467 themeOf ubiquitin,binding
R10888 T14463 T14467 themeOf ABIN1,binding
R10891 T14471 T14472 themeOf A20,deficiency
R10894 T14474 T14476 themeOf NF-κB,activation
R10899 T14475 T14477 themeOf IRF3,activation
R10900 T14476 T14478 themeOf activation,mediate
R10902 T14477 T14479 themeOf activation,mediate
R10904 T14483 T14485 themeOf A20,expression

testone

Id Subject Object Predicate Lexical cue
T11608 1066-1075 Regulation denotes affecting
T11612 2262-2272 Negative_regulation denotes deficiency
T11611 2108-2118 Gene_expression denotes expression
T11610 1416-1426 Negative_regulation denotes deficiency
T11609 1314-1328 Negative_regulation denotes ubiquitination
T11607 1055-1065 Negative_regulation denotes negatively
T11606 1010-1017 Negative_regulation denotes disrupt
T11605 539-549 Positive_regulation denotes activation
T11604 382-390 Negative_regulation denotes inhibits
T11603 17-26 Negative_regulation denotes deficient
T11596 2163-2168 Protein denotes RIG-I
T11595 1870-1875 Protein denotes IRF-3
T11594 1841-1846 Protein denotes RIG-I
T11593 1753-1757 Protein denotes CYLD
T11592 1551-1555 Protein denotes IRF3
T11591 1341-1345 Protein denotes IKKε
T11590 1332-1336 Protein denotes TBK1
T11589 1225-1230 Protein denotes RIG-I
T11588 1147-1151 Protein denotes IRF3
T11587 1111-1115 Protein denotes IKKε
T11586 1102-1106 Protein denotes TBK1
T11585 998-1003 Protein denotes ABIN1
T11584 787-791 Protein denotes IRF3
T11583 534-538 Protein denotes IRF3
T11582 493-497 Protein denotes IFNβ
T11581 482-487 Protein denotes MIP-2
T11580 478-480 Protein denotes KC
T11579 472-476 Protein denotes IL-6
T11578 467-470 Protein denotes TNF
T11577 345-350 Protein denotes RIG-I
T11576 146-151 Protein denotes RIG-I
T11575 90-95 Protein denotes RIG-I
T11574 59-63 Protein denotes IRF3
R8466 T11581 T11605 themeOf MIP-2,activation
R8467 T11583 T11605 themeOf IRF3,activation
R8468 T11590 T11609 themeOf TBK1,ubiquitination
R8469 T11591 T11609 themeOf IKKε,ubiquitination