PMC:3291650 / 15209-17622 JSON TXT

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test3

Id	Subject	Object	Predicate	Lexical cue
T20278	1309-1313	Protein	denotes	IFNβ
T20277	1300-1304	Protein	denotes	IL-6
T20276	1214-1229	Transcription	denotes	mRNA expression
T20275	1209-1213	Protein	denotes	IFNβ
T20274	1200-1204	Protein	denotes	IL-6
T20273	1048-1052	Protein	denotes	IFNβ
T20272	1040-1043	Protein	denotes	TNF
T20271	932-947	Transcription	denotes	mRNA expression
T20270	919-923	Protein	denotes	IFNβ
T20269	913-917	Protein	denotes	IL-6
T20268	1309-1313	Protein	denotes	IFNβ
T20267	1300-1304	Protein	denotes	IL-6
T20266	1209-1213	Protein	denotes	IFNβ
T20265	1200-1204	Protein	denotes	IL-6
T20264	1048-1052	Protein	denotes	IFNβ
T20263	1040-1043	Protein	denotes	TNF
T20262	919-923	Protein	denotes	IFNβ
T20261	913-917	Protein	denotes	IL-6
T7695	2402-2412	Positive_regulation	denotes	activation
T7694	2397-2401	Protein	denotes	IRF3
T7693	2373-2378	Protein	denotes	RIG-I
T7692	2090-2097	Negative_regulation	denotes	lacking
T7691	2036-2041	Protein	denotes	cxcl1
T7690	2032-2034	Protein	denotes	KC
T7689	2022-2026	Protein	denotes	ccl2
T7688	2015-2020	Protein	denotes	MCP-1
T7687	1990-1995	Protein	denotes	IFNα4
T7686	1981-1985	Protein	denotes	IFNβ
T7685	1961-1964	Protein	denotes	TNF
T7684	1952-1956	Protein	denotes	IL-6
T7683	1909-1918	Gene_expression	denotes	secretion
T7682	1894-1904	Gene_expression	denotes	Expression
T7681	605-609	Protein	denotes	IFNβ
T7680	597-600	Protein	denotes	TNF
T7679	418-422	Protein	denotes	IFNβ
T7678	409-413	Protein	denotes	IL-6
T7677	395-405	Gene_expression	denotes	expression
T7676	386-394	Positive_regulation	denotes	enhanced
T7675	302-311	Negative_regulation	denotes	deficient
T7674	182-191	Negative_regulation	denotes	deficient
T7673	2397-2401	Protein	denotes	IRF3
T7672	2373-2378	Protein	denotes	RIG-I
T7671	2036-2041	Protein	denotes	cxcl1
T7670	2032-2034	Protein	denotes	KC
T7669	2022-2026	Protein	denotes	ccl2
T7668	2015-2020	Protein	denotes	MCP-1
T7667	1990-1995	Protein	denotes	IFNα4
T7666	1981-1985	Protein	denotes	IFNβ
T7665	1961-1964	Protein	denotes	TNF
T7664	1952-1956	Protein	denotes	IL-6
T7663	605-609	Protein	denotes	IFNβ
T7662	597-600	Protein	denotes	TNF
T7661	418-422	Protein	denotes	IFNβ
T7660	409-413	Protein	denotes	IL-6
R5394	T7677	T7676	themeOf	expression,enhanced
R5395	T7678	T7677	themeOf	IL-6,expression
R5396	T7679	T7677	themeOf	IFNβ,expression
R5397	T7684	T7683	themeOf	IL-6,secretion
R5398	T7684	T7682	themeOf	IL-6,Expression
R5399	T7685	T7682	themeOf	TNF,Expression
R5400	T7685	T7683	themeOf	TNF,secretion
R5401	T7686	T7682	themeOf	IFNβ,Expression
R5402	T7686	T7683	themeOf	IFNβ,secretion
R5403	T7687	T7682	themeOf	IFNα4,Expression
R5404	T7687	T7683	themeOf	IFNα4,secretion
R5405	T7688	T7683	themeOf	MCP-1,secretion
R5406	T7688	T7682	themeOf	MCP-1,Expression
R5407	T7689	T7688	equivalentTo	ccl2,MCP-1
R5408	T7690	T7682	themeOf	KC,Expression
R5409	T7690	T7683	themeOf	KC,secretion
R5410	T7691	T7688	equivalentTo	cxcl1,MCP-1
R5411	T7691	T7690	equivalentTo	cxcl1,KC
R5412	T7694	T7695	themeOf	IRF3,activation
R15139	T20269	T20271	themeOf	IL-6,mRNA expression
R15140	T20270	T20271	themeOf	IFNβ,mRNA expression
R15141	T20274	T20276	themeOf	IL-6,mRNA expression
R15142	T20275	T20276	themeOf	IFNβ,mRNA expression

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T20474	1495-1500	CD	denotes	0,001
T20473	1494-1495	SYM	denotes	<
T20472	1490-1494	NN	denotes	***p
T20471	1477-1489	NN	denotes	experiments.
T20470	1465-1476	JJ	denotes	independent
T20469	1463-1464	CD	denotes	2
T20468	1459-1462	IN	denotes	for
T20467	1444-1458	JJ	denotes	representative
T20466	1440-1443	VB	denotes	are
T20465	1432-1439	NN	denotes	Results
T20464	1423-1430	NN	denotes	samples
T20463	1419-1422	CD	denotes	2–3
T20462	1416-1418	IN	denotes	of
T20461	1414-1415	-RRB-	denotes	)
T20460	1411-1414	NN	denotes	SEM
T20459	1407-1410	CC	denotes	+/−
T20458	1406-1407	-LRB-	denotes	(
T20457	1399-1405	NN	denotes	values
T20456	1394-1398	JJ	denotes	mean
T20455	1384-1393	VB	denotes	represent
T20454	1379-1383	NN	denotes	bars
T20453	1373-1378	NN	denotes	Error
T20452	1370-1371	-RRB-	denotes	)
T20451	1369-1370	NN	denotes	D
T20450	1368-1369	-LRB-	denotes	(
T20449	1355-1367	NN	denotes	technologies
T20448	1342-1354	JJ	denotes	multiplexing
T20447	1338-1341	CC	denotes	and
T20446	1332-1337	NN	denotes	ELISA
T20445	1329-1331	IN	denotes	by
T20444	1322-1328	NN	denotes	levels
T20443	1314-1321	NN	denotes	protein
T20442	1309-1313	NN	denotes	IFNβ
T20441	1305-1308	CC	denotes	and
T20440	1300-1304	NN	denotes	IL-6
T20439	1296-1299	IN	denotes	for
T20438	1287-1295	VB	denotes	analyzed
T20437	1283-1286	VB	denotes	was
T20436	1271-1282	NN	denotes	supernatant
T20435	1263-1270	NN	denotes	culture
T20434	1258-1262	NN	denotes	Cell
T20433	1255-1256	-RRB-	denotes	)
T20432	1254-1255	NN	denotes	C
T20431	1253-1254	-LRB-	denotes	(
T20430	1248-1252	NN	denotes	qPCR
T20429	1245-1247	IN	denotes	by
T20428	1234-1244	VB	denotes	determined
T20427	1230-1233	VB	denotes	was
T20426	1219-1229	NN	denotes	expression
T20425	1214-1218	NN	denotes	mRNA
T20424	1209-1213	NN	denotes	IFNβ
T20423	1205-1208	CC	denotes	and
T20422	1200-1204	NN	denotes	IL-6
T20421	1181-1186	NN	denotes	i 1)
T20420	1179-1181	CD	denotes	mo
T20419	1176-1179	IN	denotes	V (
T20418	1175-1176	-RRB-	denotes	A
T20417	1174-1175	CD	denotes	I
T20416	1170-1173	NN	denotes	ith
T20415	1169-1170	-LRB-	denotes	w
T20414	1165-1168	NN	denotes	ted
T20413	1161-1165	IN	denotes	nfec
T20412	1153-1161	VB	denotes	ted or i
T20411	1151-1153	CC	denotes	ea
T20410	1144-1151	VB	denotes	mock tr
T20409	1139-1143	JJ	denotes	were
T20408	1135-1139	VB	denotes	ges
T20407	1124-1135	NN	denotes	ar macropha
T20406	1116-1124	JJ	denotes	) Alveol
T20405	1115-1116	-RRB-	denotes	D
T20404	1112-1115	NN	denotes	(C–
T20403	1110-1111	-LRB-	denotes	.
T20402	1109-1110	-RRB-	denotes	)
T20401	1108-1109	NN	denotes	B
T20400	1107-1108	-LRB-	denotes	(
T20399	1094-1106	NN	denotes	technologies
T20398	1081-1093	JJ	denotes	multiplexing
T20397	1077-1080	CC	denotes	and
T20396	1071-1076	NN	denotes	ELISA
T20395	1068-1070	IN	denotes	by
T20394	1061-1067	NN	denotes	levels
T20393	1053-1060	NN	denotes	protein
T20392	1048-1052	NN	denotes	IFNβ
T20391	1044-1047	CC	denotes	and
T20390	1040-1043	NN	denotes	TNF
T20389	1036-1039	IN	denotes	for
T20388	1027-1035	VB	denotes	analyzed
T20387	1023-1026	VB	denotes	was
T20386	1011-1022	NN	denotes	supernatant
T20385	1003-1010	NN	denotes	culture
T20384	998-1002	NN	denotes	cell
T20383	988-997	NN	denotes	infection
T20382	983-987	VB	denotes	post
T20381	977-982	NN	denotes	hours
T20380	974-976	CD	denotes	18
T20379	971-972	-RRB-	denotes	)
T20378	970-971	NN	denotes	A
T20377	969-970	-LRB-	denotes	(
T20376	964-968	NN	denotes	qPCR
T20375	961-963	IN	denotes	by
T20374	952-960	VB	denotes	analyzed
T20373	948-951	VB	denotes	was
T20372	937-947	NN	denotes	expression
T20371	932-936	NN	denotes	mRNA
T20370	928-931	NN	denotes	A20
T20369	924-927	CC	denotes	and
T20368	919-923	NN	denotes	IFNβ
T20367	917-918	-COMMA-	denotes	,
T20366	913-917	NN	denotes	IL-6
T20365	909-912	CC	denotes	and
T20364	903-908	VB	denotes	lysed
T20363	898-902	VB	denotes	were
T20362	892-897	NN	denotes	cells
T20361	890-891	-RRB-	denotes	)
T20360	886-890	NN	denotes	p.i.
T20359	880-885	NN	denotes	hours
T20358	879-880	-LRB-	denotes	(
T20357	869-878	NN	denotes	infection
T20356	864-868	NN	denotes	post
T20355	858-863	NN	denotes	hours
T20354	848-857	JJ	denotes	different
T20353	845-847	IN	denotes	At
T20352	842-843	-RRB-	denotes	)
T20351	841-842	CD	denotes	1
T20350	837-840	NN	denotes	moi
T20349	836-837	-LRB-	denotes	(
T20348	832-835	NN	denotes	IAV
T20347	827-831	IN	denotes	with
T20346	818-826	VB	denotes	infected
T20345	813-817	VB	denotes	were
T20344	805-812	NN	denotes	animals
T20343	794-804	NN	denotes	A20myel-KO
T20342	790-793	CC	denotes	and
T20341	779-789	NN	denotes	A20myel-WT
T20340	774-778	IN	denotes	from
T20339	765-773	VB	denotes	isolated
T20338	760-764	NN	denotes	BMDM
T20337	758-759	-RRB-	denotes	)
T20336	755-758	NN	denotes	A–B
T20335	754-755	-LRB-	denotes	(
T20334	741-752	NN	denotes	macrophages
T20333	732-740	JJ	denotes	alveolar
T20332	728-731	CC	denotes	and
T20331	723-727	NN	denotes	BMDM
T20330	720-722	IN	denotes	in
T20329	709-719	NN	denotes	expression
T20328	704-708	NN	denotes	gene
T20327	692-703	JJ	denotes	IAV-induced
T20326	682-691	VB	denotes	regulates
T20325	671-681	RB	denotes	negatively
T20324	667-670	NN	denotes	A20
T8064	2402-2412	NN	denotes	activation
T8063	2397-2401	NN	denotes	IRF3
T8062	2393-2396	CC	denotes	and
T8061	2387-2392	NN	denotes	NF-κB
T8060	2373-2386	JJ	denotes	RIG-I-induced
T8059	2370-2372	IN	denotes	on
T8058	2365-2369	VB	denotes	seen
T8057	2361-2364	NN	denotes	A20
T8056	2358-2360	IN	denotes	of
T8055	2351-2357	NN	denotes	effect
T8054	2340-2350	JJ	denotes	inhibitory
T8053	2336-2339	DT	denotes	the
T8052	2331-2335	IN	denotes	with
T8051	2320-2330	JJ	denotes	consistent
T8050	2318-2319	-COMMA-	denotes	,
T8049	2307-2318	NN	denotes	macrophages
T8048	2298-2306	JJ	denotes	alveolar
T8047	2295-2297	IN	denotes	in
T8046	2284-2294	NN	denotes	expression
T8045	2279-2283	NN	denotes	gene
T8044	2269-2278	JJ	denotes	antiviral
T8043	2265-2268	CC	denotes	and
T8042	2249-2264	JJ	denotes	proinflammatory
T8041	2237-2248	JJ	denotes	IAV-induced
T8040	2227-2236	VB	denotes	regulates
T8039	2216-2226	RB	denotes	negatively
T8038	2212-2215	NN	denotes	A20
T8037	2207-2211	IN	denotes	that
T8036	2195-2206	VB	denotes	demonstrate
T8035	2187-2194	NN	denotes	results
T8034	2181-2186	DT	denotes	these
T8033	2172-2180	RB	denotes	together
T8032	2166-2171	VB	denotes	Taken
T8031	2163-2164	-RRB-	denotes	)
T8030	2161-2163	NN	denotes	S1
T8029	2154-2160	NN	denotes	figure
T8028	2150-2153	CC	denotes	and
T8027	2147-2149	NN	denotes	2C
T8026	2140-2146	NN	denotes	figure
T8010	2043-2046	VB	denotes	was
T8009	2041-2042	-RRB-	denotes	)
T8008	2036-2041	NN	denotes	cxcl1
T8007	2035-2036	-LRB-	denotes	(
T8006	2032-2034	NN	denotes	KC
T8005	2028-2031	CC	denotes	and
T8004	2026-2027	-RRB-	denotes	)
T8003	2022-2026	NN	denotes	ccl2
T8002	2021-2022	-LRB-	denotes	(
T8001	2015-2020	NN	denotes	MCP-1
T8000	2004-2014	NN	denotes	chemokines
T7999	2000-2003	DT	denotes	the
T7998	1996-1999	CC	denotes	and
T7997	1990-1995	NN	denotes	IFNα4
T7996	1986-1989	CC	denotes	and
T7995	1981-1985	NN	denotes	IFNβ
T7994	1977-1980	NN	denotes	IFN
T7993	1970-1976	NN	denotes	type-I
T7992	1966-1969	DT	denotes	the
T7991	1964-1965	-COMMA-	denotes	,
T7990	1961-1964	NN	denotes	TNF
T7989	1957-1960	CC	denotes	and
T7988	1952-1956	NN	denotes	IL-6
T7987	1942-1951	NN	denotes	cytokines
T7986	1926-1941	JJ	denotes	proinflammatory
T7985	1922-1925	DT	denotes	the
T7984	1919-1921	IN	denotes	of
T7983	1909-1918	NN	denotes	secretion
T7982	1905-1908	CC	denotes	and
T7981	1894-1904	NN	denotes	Expression
T7980	1888-1892	NN	denotes	X-47
T7979	1884-1887	NN	denotes	IAV
T7978	1879-1883	IN	denotes	with
T7977	1873-1878	FW	denotes	vitro
T7976	1870-1872	FW	denotes	in
T7975	1865-1869	PRP	denotes	them
T7974	1856-1864	VB	denotes	infected
T7973	1852-1855	CC	denotes	and
T7972	1840-1851	NN	denotes	littermates
T7971	1832-1839	NN	denotes	control
T7970	1828-1831	CC	denotes	and
T7969	1817-1827	NN	denotes	A20myel-KO
T7968	1814-1816	IN	denotes	of
T7967	1808-1813	NN	denotes	lungs
T7966	1803-1807	IN	denotes	from
T7965	1797-1802	NN	denotes	cells
T7964	1791-1796	DT	denotes	these
T7963	1782-1790	VB	denotes	isolated
T7962	1779-1781	PRP	denotes	we
T7961	1777-1778	-COMMA-	denotes	,
T7960	1766-1777	NN	denotes	macrophages
T7959	1757-1765	JJ	denotes	alveolar
T7958	1754-1756	IN	denotes	in
T7957	1743-1753	NN	denotes	expression
T7956	1738-1742	NN	denotes	gene
T7955	1726-1737	JJ	denotes	IAV-induced
T7954	1717-1725	VB	denotes	controls
T7953	1708-1716	RB	denotes	directly
T7952	1704-1707	NN	denotes	A20
T7951	1696-1703	IN	denotes	whether
T7950	1691-1695	VB	denotes	test
T7949	1688-1690	TO	denotes	To
T7948	1677-1686	NN	denotes	infection
T7947	1674-1676	IN	denotes	of
T7946	1668-1673	NN	denotes	phase
T7945	1660-1667	JJ	denotes	primary
T7944	1656-1659	DT	denotes	the
T7943	1649-1655	IN	denotes	during
T7942	1644-1648	NN	denotes	lung
T7941	1640-1643	DT	denotes	the
T7940	1637-1639	TO	denotes	to
T7939	1631-1636	NN	denotes	cells
T7938	1624-1630	JJ	denotes	immune
T7937	1617-1623	JJ	denotes	innate
T7936	1606-1616	VB	denotes	attracting
T7935	1604-1605	-COMMA-	denotes	,
T7934	1594-1604	NN	denotes	chemokines
T7933	1590-1593	CC	denotes	and
T7932	1580-1589	NN	denotes	cytokines
T7931	1577-1579	IN	denotes	of
T7930	1570-1576	NN	denotes	source
T7929	1560-1569	JJ	denotes	important
T7928	1557-1559	DT	denotes	an
T7927	1553-1556	VB	denotes	are
T7926	1541-1552	NN	denotes	macrophages
T7925	1532-1540	JJ	denotes	alveolar
T7924	1530-1531	-COMMA-	denotes	,
T7923	1527-1530	NN	denotes	IAV
T7922	1522-1526	IN	denotes	with
T7921	1512-1521	NN	denotes	infection
T7920	1507-1511	NN	denotes	host
T7919	1502-1506	IN	denotes	Upon
T7918	620-621	-RRB-	denotes	)
T7917	618-620	NN	denotes	2B
T7916	611-617	NN	denotes	figure
T7915	610-611	-LRB-	denotes	(
T7914	605-609	NN	denotes	IFNβ
T7913	601-604	CC	denotes	and
T7912	597-600	NN	denotes	TNF
T7911	594-596	IN	denotes	of
T7910	587-593	NN	denotes	levels
T7909	580-586	JJ	denotes	higher
T7908	570-579	VB	denotes	contained
T7907	564-569	NN	denotes	cells
T7906	558-563	DT	denotes	these
T7905	553-557	IN	denotes	from
T7904	543-552	VB	denotes	collected
T7903	531-542	NN	denotes	supernatant
T7902	523-530	NN	denotes	culture
T7901	518-522	NN	denotes	cell
T7900	516-517	-COMMA-	denotes	,
T7899	512-516	NN	denotes	data
T7898	506-511	DT	denotes	these
T7897	501-505	IN	denotes	with
T7896	490-500	NN	denotes	accordance
T7895	487-489	IN	denotes	In
T7894	484-485	-RRB-	denotes	)
T7893	482-484	NN	denotes	2A
T7892	475-481	NN	denotes	figure
T7891	474-475	-LRB-	denotes	(
T7890	468-473	NN	denotes	cells
T7889	460-467	NN	denotes	control
T7888	457-459	TO	denotes	to
T7887	448-456	VB	denotes	compared
T7886	438-447	NN	denotes	infection
T7885	434-437	NN	denotes	IAV
T7884	428-433	IN	denotes	after
T7883	423-427	NN	denotes	mRNA
T7882	418-422	NN	denotes	IFNβ
T7881	414-417	CC	denotes	and
T7880	409-413	NN	denotes	IL-6
T7879	406-408	IN	denotes	of
T7878	395-405	NN	denotes	expression
T7877	386-394	VB	denotes	enhanced
T7876	381-385	VB	denotes	show
T7875	376-380	NN	denotes	BMDM
T7874	365-375	NN	denotes	A20myel-KO
T7873	363-364	-COMMA-	denotes	,
T7872	352-363	RB	denotes	Furthermore
T7871	349-350	-RRB-	denotes	)
T7870	347-349	NN	denotes	2A
T7869	340-346	NN	denotes	figure
T7868	339-340	-LRB-	denotes	(
T7867	329-338	NN	denotes	infection
T7866	323-328	JJ	denotes	viral
T7865	318-322	IN	denotes	upon
T7864	316-317	-COMMA-	denotes	,
T7863	312-316	NN	denotes	BMDM
T7862	302-311	JJ	denotes	deficient
T7861	298-301	NN	denotes	A20
T7860	295-297	IN	denotes	in
T7859	291-294	RB	denotes	not
T7858	287-290	CC	denotes	but
T7857	285-286	-COMMA-	denotes	,
T7856	281-285	NN	denotes	BMDM
T7855	276-280	NN	denotes	type
T7854	271-275	JJ	denotes	wild
T7853	268-270	IN	denotes	in
T7852	260-267	VB	denotes	induced
T7851	252-259	RB	denotes	rapidly
T7850	247-251	VB	denotes	were
T7849	240-246	NN	denotes	levels
T7848	235-239	NN	denotes	mRNA
T7847	231-234	NN	denotes	A20
T7846	228-229	-RRB-	denotes	)
T7845	224-228	NN	denotes	H3N2
T7844	223-224	-LRB-	denotes	(
T7843	218-222	NN	denotes	X-47
T7842	214-217	NN	denotes	IAV
T7841	209-213	IN	denotes	with
T7840	204-208	NN	denotes	BMDM
T7839	196-203	NN	denotes	control
T7838	192-195	CC	denotes	and
T7837	182-191	JJ	denotes	deficient
T7836	178-181	NN	denotes	A20
T7835	169-177	VB	denotes	infected
T7834	166-168	PRP	denotes	we
T7833	164-165	-COMMA-	denotes	,
T7832	155-164	NN	denotes	responses
T7831	148-154	JJ	denotes	immune
T7830	141-147	JJ	denotes	innate
T7829	131-140	JJ	denotes	antiviral
T7828	127-130	CC	denotes	and
T7827	111-126	JJ	denotes	proinflammatory
T7826	99-110	JJ	denotes	IAV-induced
T7825	95-98	DT	denotes	the
T7824	92-94	IN	denotes	in
T7823	88-91	NN	denotes	A20
T7822	85-87	IN	denotes	of
T7821	80-84	NN	denotes	role
T7820	76-79	DT	denotes	the
T7819	64-75	VB	denotes	investigate
T7818	61-63	TO	denotes	To
T7817	56-60	NN	denotes	BMDM
T7816	53-55	IN	denotes	in
T7815	42-52	NN	denotes	expression
T7814	37-41	NN	denotes	gene
T7813	25-36	JJ	denotes	IAV-induced
T7812	15-24	VB	denotes	regulates
T7811	4-14	RB	denotes	negatively
T7810	0-3	NN	denotes	A20
T8025	2139-2140	-LRB-	denotes	(
T8024	2133-2138	NN	denotes	cells
T8023	2128-2132	NN	denotes	type
T8022	2123-2127	JJ	denotes	wild
T8021	2114-2122	JJ	denotes	infected
T8020	2111-2113	TO	denotes	to
T8019	2102-2110	VB	denotes	compared
T8018	2098-2101	NN	denotes	A20
T8017	2090-2097	VB	denotes	lacking
T8016	2084-2089	NN	denotes	cells
T8015	2075-2083	JJ	denotes	infected
T8014	2071-2074	NN	denotes	IAV
T8013	2068-2070	IN	denotes	in
T8012	2061-2067	JJ	denotes	higher
T8011	2047-2060	RB	denotes	significantly
R5449	T7810	T7812	arg1Of	A20,regulates
R5450	T7812	T7811	arg1Of	regulates,negatively
R5451	T7815	T7812	arg2Of	expression,regulates
R5452	T7815	T7813	arg1Of	expression,IAV-induced
R5453	T7815	T7814	arg1Of	expression,gene
R5454	T7815	T7816	arg1Of	expression,in
R5455	T7817	T7816	arg2Of	BMDM,in
R5456	T7819	T7818	arg1Of	investigate,To
R5457	T7821	T7819	arg2Of	role,investigate
R5458	T7821	T7820	arg1Of	role,the
R5459	T7821	T7822	arg1Of	role,of
R5460	T7821	T7824	arg1Of	role,in
R5461	T7823	T7822	arg2Of	A20,of
R5462	T7827	T7826	arg1Of	proinflammatory,IAV-induced
R5463	T7827	T7828	arg1Of	proinflammatory,and
R5464	T7831	T7828	arg2Of	immune,and
R5465	T7831	T7829	arg1Of	immune,antiviral
R5466	T7831	T7830	arg1Of	immune,innate
R5467	T7832	T7824	arg2Of	responses,in
R5468	T7832	T7825	arg1Of	responses,the
R5469	T7832	T7827	arg1Of	responses,proinflammatory
R5470	T7832	T7831	arg1Of	responses,immune
R5471	T7834	T7819	arg1Of	we,investigate
R5472	T7834	T7835	arg1Of	we,infected
R5473	T7835	T7818	modOf	infected,To
R5474	T7835	T7833	arg1Of	infected,","
R5475	T7836	T7837	arg1Of	A20,deficient
R5476	T7836	T7838	arg1Of	A20,and
R5477	T7838	T7835	arg2Of	and,infected
R5478	T7838	T7841	arg1Of	and,with
R5479	T7840	T7838	arg2Of	BMDM,and
R5480	T7840	T7839	arg1Of	BMDM,control
R5481	T7843	T7841	arg2Of	X-47,with
R5482	T7843	T7842	arg1Of	X-47,IAV
R5483	T7843	T7844	arg1Of	X-47,(
R5484	T7845	T7844	arg2Of	H3N2,(
R5485	T7846	T7844	arg3Of	),(
R5486	T7849	T7847	arg1Of	levels,A20
R5487	T7849	T7848	arg1Of	levels,mRNA
R5488	T7849	T7850	arg1Of	levels,were
R5489	T7849	T7852	arg2Of	levels,induced
R5490	T7852	T7850	arg2Of	induced,were
R5491	T7852	T7851	arg1Of	induced,rapidly
R5492	T7852	T7853	arg1Of	induced,in
R5493	T7852	T7860	arg1Of	induced,in
R5494	T7852	T7864	arg1Of	induced,","
R5495	T7852	T7865	arg1Of	induced,upon
R5496	T7853	T7858	arg1Of	in,but
R5497	T7856	T7853	arg2Of	BMDM,in
R5498	T7856	T7854	arg1Of	BMDM,wild
R5499	T7856	T7855	arg1Of	BMDM,type
R5500	T7858	T7857	arg1Of	but,","
R5501	T7860	T7858	arg2Of	in,but
R5502	T7860	T7859	arg1Of	in,not
R5503	T7863	T7860	arg2Of	BMDM,in
R5504	T7863	T7861	arg1Of	BMDM,A20
R5505	T7863	T7862	arg1Of	BMDM,deficient
R5506	T7867	T7865	arg2Of	infection,upon
R5507	T7867	T7866	arg1Of	infection,viral
R5508	T7867	T7868	arg1Of	infection,(
R5509	T7870	T7868	arg2Of	2A,(
R5510	T7870	T7869	arg1Of	2A,figure
R5511	T7871	T7868	arg3Of	),(
R5512	T7875	T7874	arg1Of	BMDM,A20myel-KO
R5513	T7875	T7876	arg1Of	BMDM,show
R5514	T7876	T7872	arg1Of	show,Furthermore
R5515	T7876	T7873	arg1Of	show,","
R5516	T7876	T7887	arg1Of	show,compared
R5517	T7878	T7876	arg2Of	expression,show
R5518	T7878	T7877	arg2Of	expression,enhanced
R5519	T7878	T7879	arg1Of	expression,of
R5520	T7878	T7884	arg1Of	expression,after
R5521	T7880	T7881	arg1Of	IL-6,and
R5522	T7882	T7881	arg2Of	IFNβ,and
R5523	T7883	T7879	arg2Of	mRNA,of
R5524	T7883	T7880	arg1Of	mRNA,IL-6
R5525	T7883	T7882	arg1Of	mRNA,IFNβ
R5526	T7886	T7884	arg2Of	infection,after
R5527	T7886	T7885	arg1Of	infection,IAV
R5528	T7888	T7887	arg2Of	to,compared
R5529	T7890	T7888	arg2Of	cells,to
R5530	T7890	T7889	arg1Of	cells,control
R5531	T7890	T7891	arg1Of	cells,(
R5532	T7893	T7891	arg2Of	2A,(
R5533	T7893	T7892	arg1Of	2A,figure
R5534	T7894	T7891	arg3Of	),(
R5535	T7896	T7895	arg2Of	accordance,In
R5536	T7896	T7897	arg1Of	accordance,with
R5537	T7899	T7897	arg2Of	data,with
R5538	T7899	T7898	arg1Of	data,these
R5539	T7903	T7901	arg1Of	supernatant,cell
R5540	T7903	T7902	arg1Of	supernatant,culture
R5541	T7903	T7904	arg2Of	supernatant,collected
R5542	T7903	T7908	arg1Of	supernatant,contained
R5543	T7904	T7905	arg1Of	collected,from
R5544	T7907	T7905	arg2Of	cells,from
R5545	T7907	T7906	arg1Of	cells,these
R5546	T7908	T7895	arg1Of	contained,In
R5547	T7908	T7900	arg1Of	contained,","
R5548	T7910	T7908	arg2Of	levels,contained
R5549	T7910	T7909	arg1Of	levels,higher
R5550	T7910	T7911	arg1Of	levels,of
R5551	T7912	T7913	arg1Of	TNF,and
R5552	T7913	T7911	arg2Of	and,of
R5553	T7913	T7915	arg1Of	and,(
R5554	T7914	T7913	arg2Of	IFNβ,and
R5555	T7917	T7915	arg2Of	2B,(
R5556	T7917	T7916	arg1Of	2B,figure
R5557	T7918	T7915	arg3Of	),(
R5558	T7921	T7919	arg2Of	infection,Upon
R5559	T7921	T7920	arg1Of	infection,host
R5560	T7921	T7922	arg1Of	infection,with
R5561	T7923	T7922	arg2Of	IAV,with
R5562	T7926	T7925	arg1Of	macrophages,alveolar
R5563	T7926	T7927	arg1Of	macrophages,are
R5564	T7926	T7936	arg1Of	macrophages,attracting
R5565	T7927	T7919	arg1Of	are,Upon
R5566	T7927	T7924	arg1Of	are,","
R5567	T7927	T7935	arg1Of	are,","
R5568	T7927	T7936	modOf	are,attracting
R5569	T7930	T7927	arg2Of	source,are
R5570	T7930	T7928	arg1Of	source,an
R5571	T7930	T7929	arg1Of	source,important
R5572	T7930	T7931	arg1Of	source,of
R5573	T7932	T7933	arg1Of	cytokines,and
R5574	T7933	T7931	arg2Of	and,of
R5575	T7934	T7933	arg2Of	chemokines,and
R5576	T7936	T7940	arg1Of	attracting,to
R5577	T7936	T7943	arg1Of	attracting,during
R5578	T7939	T7936	arg2Of	cells,attracting
R5579	T7939	T7937	arg1Of	cells,innate
R5580	T7939	T7938	arg1Of	cells,immune
R5581	T7942	T7940	arg2Of	lung,to
R5582	T7942	T7941	arg1Of	lung,the
R5583	T7946	T7943	arg2Of	phase,during
R5584	T7946	T7944	arg1Of	phase,the
R5585	T7946	T7945	arg1Of	phase,primary
R5586	T7946	T7947	arg1Of	phase,of
R5587	T7948	T7947	arg2Of	infection,of
R5588	T7950	T7949	arg1Of	test,To
R5589	T7952	T7954	arg1Of	A20,controls
R5590	T7954	T7950	arg2Of	controls,test
R5591	T7954	T7951	arg1Of	controls,whether
R5592	T7954	T7953	arg1Of	controls,directly
R5593	T7957	T7954	arg2Of	expression,controls
R5594	T7957	T7955	arg1Of	expression,IAV-induced
R5595	T7957	T7956	arg1Of	expression,gene
R5596	T7957	T7958	arg1Of	expression,in
R5597	T7960	T7958	arg2Of	macrophages,in
R5598	T7960	T7959	arg1Of	macrophages,alveolar
R5599	T7962	T7950	arg1Of	we,test
R5600	T7962	T7963	arg1Of	we,isolated
R5601	T7962	T7974	arg1Of	we,infected
R5602	T7963	T7973	arg1Of	isolated,and
R5603	T7965	T7963	arg2Of	cells,isolated
R5604	T7965	T7964	arg1Of	cells,these
R5605	T7965	T7966	arg1Of	cells,from
R5606	T7967	T7966	arg2Of	lungs,from
R5607	T7967	T7968	arg1Of	lungs,of
R5608	T7969	T7970	arg1Of	A20myel-KO,and
R5609	T7971	T7970	arg2Of	control,and
R5610	T7972	T7968	arg2Of	littermates,of
R5611	T7972	T7969	arg1Of	littermates,A20myel-KO
R5612	T7972	T7971	arg1Of	littermates,control
R5613	T7973	T7949	modOf	and,To
R5614	T7973	T7961	arg1Of	and,","
R5615	T7974	T7973	arg2Of	infected,and
R5616	T7974	T7977	arg1Of	infected,vitro
R5617	T7974	T7978	arg1Of	infected,with
R5618	T7975	T7974	arg2Of	them,infected
R5619	T7977	T7976	arg1Of	vitro,in
R5620	T7980	T7978	arg2Of	X-47,with
R5621	T7980	T7979	arg1Of	X-47,IAV
R5622	T7981	T7982	arg1Of	Expression,and
R5623	T7982	T7984	arg1Of	and,of
R5624	T7982	T8005	arg1Of	and,and
R5625	T7983	T7982	arg2Of	secretion,and
R5626	T7987	T7985	arg1Of	cytokines,the
R5627	T7987	T7986	arg1Of	cytokines,proinflammatory
R5628	T7988	T7989	arg1Of	IL-6,and
R5629	T7989	T7984	arg2Of	and,of
R5630	T7989	T7987	arg1Of	and,cytokines
R5631	T7989	T7991	arg1Of	and,","
R5632	T7990	T7989	arg2Of	TNF,and
R5633	T7995	T7996	arg1Of	IFNβ,and
R5634	T7996	T7992	arg1Of	and,the
R5635	T7996	T7993	arg1Of	and,type-I
R5636	T7996	T7994	arg1Of	and,IFN
R5637	T7996	T7998	arg1Of	and,and
R5638	T7997	T7996	arg2Of	IFNα4,and
R5639	T7998	T7991	arg2Of	and,","
R5640	T8001	T7998	arg2Of	MCP-1,and
R5641	T8001	T7999	arg1Of	MCP-1,the
R5642	T8001	T8000	arg1Of	MCP-1,chemokines
R5643	T8001	T8002	arg1Of	MCP-1,(
R5644	T8003	T8002	arg2Of	ccl2,(
R5645	T8004	T8002	arg3Of	),(
R5646	T8005	T8010	arg1Of	and,was
R5647	T8005	T8012	arg1Of	and,higher
R5648	T8006	T8005	arg2Of	KC,and
R5649	T8006	T8007	arg1Of	KC,(
R5650	T8008	T8007	arg2Of	cxcl1,(
R5651	T8009	T8007	arg3Of	),(
R5652	T8012	T8010	arg2Of	higher,was
R5653	T8012	T8011	arg1Of	higher,significantly
R5654	T8012	T8013	arg1Of	higher,in
R5655	T8016	T8013	arg2Of	cells,in
R5656	T8016	T8014	arg1Of	cells,IAV
R5657	T8016	T8015	arg1Of	cells,infected
R5658	T8016	T8017	arg1Of	cells,lacking
R5659	T8017	T8019	arg1Of	lacking,compared
R5660	T8018	T8017	arg2Of	A20,lacking
R5661	T8020	T8019	arg2Of	to,compared
R5662	T8024	T8020	arg2Of	cells,to
R5663	T8024	T8021	arg1Of	cells,infected
R5664	T8024	T8022	arg1Of	cells,wild
R5665	T8024	T8023	arg1Of	cells,type
R5666	T8024	T8025	arg1Of	cells,(
R5667	T8027	T8026	arg1Of	2C,figure
R5668	T8027	T8028	arg1Of	2C,and
R5669	T8028	T8025	arg2Of	and,(
R5670	T8030	T8028	arg2Of	S1,and
R5671	T8030	T8029	arg1Of	S1,figure
R5672	T8031	T8025	arg3Of	),(
R5673	T8032	T8033	arg1Of	Taken,together
R5674	T8035	T8034	arg1Of	results,these
R5675	T8035	T8036	arg1Of	results,demonstrate
R5676	T8036	T8032	modOf	demonstrate,Taken
R5677	T8038	T8040	arg1Of	A20,regulates
R5678	T8040	T8036	arg2Of	regulates,demonstrate
R5679	T8040	T8037	arg1Of	regulates,that
R5680	T8040	T8039	arg1Of	regulates,negatively
R5681	T8040	T8050	arg1Of	regulates,","
R5682	T8040	T8051	arg1Of	regulates,consistent
R5683	T8042	T8043	arg1Of	proinflammatory,and
R5684	T8044	T8043	arg2Of	antiviral,and
R5685	T8046	T8040	arg2Of	expression,regulates
R5686	T8046	T8041	arg1Of	expression,IAV-induced
R5687	T8046	T8042	arg1Of	expression,proinflammatory
R5688	T8046	T8044	arg1Of	expression,antiviral
R5689	T8046	T8045	arg1Of	expression,gene
R5690	T8046	T8047	arg1Of	expression,in
R5691	T8049	T8047	arg2Of	macrophages,in
R5692	T8049	T8048	arg1Of	macrophages,alveolar
R5693	T8051	T8052	arg1Of	consistent,with
R5694	T8055	T8052	arg2Of	effect,with
R5695	T8055	T8053	arg1Of	effect,the
R5696	T8055	T8054	arg1Of	effect,inhibitory
R5697	T8055	T8056	arg1Of	effect,of
R5698	T8057	T8056	arg2Of	A20,of
R5699	T8057	T8058	arg2Of	A20,seen
R5700	T8058	T8059	arg1Of	seen,on
R5701	T8061	T8060	arg1Of	NF-κB,RIG-I-induced
R5702	T8061	T8062	arg1Of	NF-κB,and
R5703	T8062	T8059	arg2Of	and,on
R5704	T8064	T8062	arg2Of	activation,and
R5705	T8064	T8063	arg1Of	activation,IRF3
R15147	T20324	T20326	arg1Of	A20,regulates
R15148	T20326	T20325	arg1Of	regulates,negatively
R15149	T20329	T20326	arg2Of	expression,regulates
R15150	T20329	T20327	arg1Of	expression,IAV-induced
R15151	T20329	T20328	arg1Of	expression,gene
R15152	T20329	T20330	arg1Of	expression,in
R15153	T20331	T20332	arg1Of	BMDM,and
R15154	T20332	T20330	arg2Of	and,in
R15155	T20334	T20332	arg2Of	macrophages,and
R15156	T20334	T20333	arg1Of	macrophages,alveolar
R15157	T20336	T20335	arg2Of	A–B,(
R15158	T20337	T20335	arg3Of	),(
R15159	T20338	T20335	arg1Of	BMDM,(
R15160	T20338	T20339	arg2Of	BMDM,isolated
R15161	T20338	T20345	arg1Of	BMDM,were
R15162	T20338	T20346	arg2Of	BMDM,infected
R15163	T20339	T20340	arg1Of	isolated,from
R15164	T20341	T20342	arg1Of	A20myel-WT,and
R15165	T20343	T20342	arg2Of	A20myel-KO,and
R15166	T20344	T20340	arg2Of	animals,from
R15167	T20344	T20341	arg1Of	animals,A20myel-WT
R15168	T20344	T20343	arg1Of	animals,A20myel-KO
R15169	T20346	T20345	arg2Of	infected,were
R15170	T20346	T20347	arg1Of	infected,with
R15171	T20348	T20347	arg2Of	IAV,with
R15172	T20348	T20349	arg1Of	IAV,(
R15173	T20350	T20349	arg2Of	moi,(
R15174	T20350	T20351	arg1Of	moi,1
R15175	T20352	T20349	arg3Of	),(
R15176	T20357	T20353	arg2Of	infection,At
R15177	T20357	T20354	arg1Of	infection,different
R15178	T20357	T20355	arg1Of	infection,hours
R15179	T20357	T20356	arg1Of	infection,post
R15180	T20360	T20358	arg2Of	p.i.,(
R15181	T20360	T20359	arg1Of	p.i.,hours
R15182	T20361	T20358	arg3Of	),(
R15183	T20362	T20358	arg1Of	cells,(
R15184	T20362	T20363	arg1Of	cells,were
R15185	T20362	T20364	arg2Of	cells,lysed
R15186	T20364	T20363	arg2Of	lysed,were
R15187	T20364	T20365	arg1Of	lysed,and
R15188	T20365	T20353	arg1Of	and,At
R15189	T20366	T20367	arg1Of	IL-6,","
R15190	T20367	T20369	arg1Of	",",and
R15191	T20368	T20367	arg2Of	IFNβ,","
R15192	T20370	T20369	arg2Of	A20,and
R15193	T20372	T20366	arg1Of	expression,IL-6
R15194	T20372	T20368	arg1Of	expression,IFNβ
R15195	T20372	T20370	arg1Of	expression,A20
R15196	T20372	T20371	arg1Of	expression,mRNA
R15197	T20372	T20373	arg1Of	expression,was
R15198	T20372	T20374	arg2Of	expression,analyzed
R15199	T20374	T20365	arg2Of	analyzed,and
R15200	T20374	T20373	arg2Of	analyzed,was
R15201	T20376	T20374	arg1Of	qPCR,analyzed
R15202	T20376	T20375	arg2Of	qPCR,by
R15203	T20376	T20377	arg1Of	qPCR,(
R15204	T20378	T20377	arg2Of	A,(
R15205	T20379	T20377	arg3Of	),(
R15206	T20381	T20380	arg1Of	hours,18
R15207	T20381	T20382	arg2Of	hours,post
R15208	T20381	T20387	arg1Of	hours,was
R15209	T20381	T20388	arg2Of	hours,analyzed
R15210	T20386	T20382	arg1Of	supernatant,post
R15211	T20386	T20383	arg1Of	supernatant,infection
R15212	T20386	T20384	arg1Of	supernatant,cell
R15213	T20386	T20385	arg1Of	supernatant,culture
R15214	T20388	T20387	arg2Of	analyzed,was
R15215	T20388	T20389	arg1Of	analyzed,for
R15216	T20390	T20391	arg1Of	TNF,and
R15217	T20392	T20391	arg2Of	IFNβ,and
R15218	T20394	T20389	arg2Of	levels,for
R15219	T20394	T20390	arg1Of	levels,TNF
R15220	T20394	T20392	arg1Of	levels,IFNβ
R15221	T20394	T20393	arg1Of	levels,protein
R15222	T20396	T20397	arg1Of	ELISA,and
R15223	T20398	T20397	arg2Of	multiplexing,and
R15224	T20399	T20388	arg1Of	technologies,analyzed
R15225	T20399	T20395	arg2Of	technologies,by
R15226	T20399	T20396	arg1Of	technologies,ELISA
R15227	T20399	T20398	arg1Of	technologies,multiplexing
R15228	T20399	T20400	arg1Of	technologies,(
R15229	T20399	T20408	modOf	technologies,ges
R15230	T20401	T20400	arg2Of	B,(
R15231	T20402	T20400	arg3Of	),(
R15232	T20404	T20403	arg2Of	(C–,.
R15233	T20405	T20403	arg3Of	D,.
R15234	T20407	T20403	arg1Of	ar macropha,.
R15235	T20407	T20406	arg1Of	ar macropha,) Alveol
R15236	T20407	T20408	arg1Of	ar macropha,ges
R15237	T20407	T20410	arg2Of	ar macropha,mock tr
R15238	T20407	T20412	arg2Of	ar macropha,ted or i
R15239	T20410	T20411	arg1Of	mock tr,ea
R15240	T20411	T20408	arg2Of	ea,ges
R15241	T20411	T20409	arg1Of	ea,were
R15242	T20412	T20411	arg2Of	ted or i,ea
R15243	T20412	T20413	arg1Of	ted or i,nfec
R15244	T20412	T20419	arg1Of	ted or i,V (
R15245	T20414	T20413	arg2Of	ted,nfec
R15246	T20414	T20415	arg1Of	ted,w
R15247	T20416	T20415	arg2Of	ith,w
R15248	T20416	T20417	arg1Of	ith,I
R15249	T20418	T20415	arg3Of	A,w
R15250	T20421	T20419	arg2Of	i 1) ,V (
R15251	T20421	T20420	arg1Of	i 1) ,mo
R15252	T20422	T20423	arg1Of	IL-6,and
R15253	T20423	T20427	arg1Of	and,was
R15254	T20423	T20428	arg2Of	and,determined
R15255	T20426	T20423	arg2Of	expression,and
R15256	T20426	T20424	arg1Of	expression,IFNβ
R15257	T20426	T20425	arg1Of	expression,mRNA
R15258	T20428	T20427	arg2Of	determined,was
R15259	T20430	T20428	arg1Of	qPCR,determined
R15260	T20430	T20429	arg2Of	qPCR,by
R15261	T20430	T20431	arg1Of	qPCR,(
R15262	T20432	T20431	arg2Of	C,(
R15263	T20433	T20431	arg3Of	),(
R15264	T20436	T20434	arg1Of	supernatant,Cell
R15265	T20436	T20435	arg1Of	supernatant,culture
R15266	T20436	T20437	arg1Of	supernatant,was
R15267	T20436	T20438	arg2Of	supernatant,analyzed
R15268	T20438	T20437	arg2Of	analyzed,was
R15269	T20438	T20439	arg1Of	analyzed,for
R15270	T20440	T20441	arg1Of	IL-6,and
R15271	T20441	T20439	arg2Of	and,for
R15272	T20444	T20441	arg2Of	levels,and
R15273	T20444	T20442	arg1Of	levels,IFNβ
R15274	T20444	T20443	arg1Of	levels,protein
R15275	T20446	T20447	arg1Of	ELISA,and
R15276	T20447	T20438	arg1Of	and,analyzed
R15277	T20447	T20445	arg2Of	and,by
R15278	T20449	T20447	arg2Of	technologies,and
R15279	T20449	T20448	arg1Of	technologies,multiplexing
R15280	T20449	T20450	arg1Of	technologies,(
R15281	T20451	T20450	arg2Of	D,(
R15282	T20452	T20450	arg3Of	),(
R15283	T20454	T20453	arg1Of	bars,Error
R15284	T20454	T20455	arg1Of	bars,represent
R15285	T20457	T20455	arg2Of	values,represent
R15286	T20457	T20456	arg1Of	values,mean
R15287	T20457	T20458	arg1Of	values,(
R15288	T20457	T20462	arg1Of	values,of
R15289	T20459	T20458	arg2Of	+/−,(
R15290	T20460	T20459	arg2Of	SEM,+/−
R15291	T20461	T20458	arg3Of	),(
R15292	T20464	T20462	arg2Of	samples,of
R15293	T20464	T20463	arg1Of	samples,2–3
R15294	T20465	T20466	arg1Of	Results,are
R15295	T20465	T20467	arg1Of	Results,representative
R15296	T20467	T20466	arg2Of	representative,are
R15297	T20467	T20468	arg1Of	representative,for
R15298	T20472	T20468	arg2Of	***p,for
R15299	T20472	T20469	arg1Of	***p,2
R15300	T20472	T20470	arg1Of	***p,independent
R15301	T20472	T20471	arg1Of	***p,experiments.
R15302	T20472	T20473	arg1Of	***p,<
R15303	T20473	T20474	arg1Of	<,"0,001"

bionlp-st-ge-2016-test-proteins

Id	Subject	Object	Predicate	Lexical cue
T7760	1981-1985	Protein	denotes	IFNβ
T7759	1961-1964	Protein	denotes	TNF
T7758	1952-1956	Protein	denotes	IL-6
T7757	605-609	Protein	denotes	IFNβ
T7756	597-600	Protein	denotes	TNF
T7755	418-422	Protein	denotes	IFNβ
T7754	409-413	Protein	denotes	IL-6
T7767	2397-2401	Protein	denotes	IRF3
T7766	2373-2378	Protein	denotes	RIG-I
T7765	2036-2041	Protein	denotes	cxcl1
T7764	2032-2034	Protein	denotes	KC
T7763	2022-2026	Protein	denotes	ccl2
T7762	2015-2020	Protein	denotes	MCP-1
T7761	1990-1995	Protein	denotes	IFNα4
T20306	1309-1313	Protein	denotes	IFNβ
T20305	1300-1304	Protein	denotes	IL-6
T20304	1209-1213	Protein	denotes	IFNβ
T20303	1200-1204	Protein	denotes	IL-6
T20302	1048-1052	Protein	denotes	IFNβ
T20301	1040-1043	Protein	denotes	TNF
T20300	919-923	Protein	denotes	IFNβ
T20299	913-917	Protein	denotes	IL-6

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T20647	1040-1043	http://www.uniprot.org/uniprot/P01375	denotes	TNF
T20646	1300-1304	http://www.uniprot.org/uniprot/P05231	denotes	IL-6
T20645	1200-1204	http://www.uniprot.org/uniprot/P05231	denotes	IL-6
T20644	913-917	http://www.uniprot.org/uniprot/P05231	denotes	IL-6
T20643	928-931	http://www.uniprot.org/uniprot/P21580	denotes	A20
T20642	667-670	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8355	2397-2401	http://www.uniprot.org/uniprot/Q14653	denotes	IRF3
T8354	1961-1964	http://www.uniprot.org/uniprot/P01375	denotes	TNF
T8353	597-600	http://www.uniprot.org/uniprot/P01375	denotes	TNF
T8352	1952-1956	http://www.uniprot.org/uniprot/P05231	denotes	IL-6
T8351	409-413	http://www.uniprot.org/uniprot/P05231	denotes	IL-6
T8350	2361-2364	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8349	2212-2215	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8348	2098-2101	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8347	1704-1707	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8346	298-301	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8345	231-234	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8344	178-181	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8343	88-91	http://www.uniprot.org/uniprot/P21580	denotes	A20
T8342	0-3	http://www.uniprot.org/uniprot/P21580	denotes	A20

UBERON-AE

Id	Subject	Object	Predicate	Lexical cue
T7697	1808-1813	http://purl.obolibrary.org/obo/UBERON_0002048	denotes	lungs
T7696	1644-1648	http://purl.obolibrary.org/obo/UBERON_0002048	denotes	lung

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T20309	1118-1126	http://purl.obolibrary.org/obo/GO_0048286	denotes	Alveolar
T20308	732-740	http://purl.obolibrary.org/obo/GO_0048286	denotes	alveolar
T20307	704-719	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression
T7784	2015-2018	http://purl.obolibrary.org/obo/GO_0004298	denotes	MCP
T7783	1909-1918	http://purl.obolibrary.org/obo/GO_0046903	denotes	secretion
T7782	2298-2306	http://purl.obolibrary.org/obo/GO_0048286	denotes	alveolar
T7781	1757-1765	http://purl.obolibrary.org/obo/GO_0048286	denotes	alveolar
T7780	1532-1540	http://purl.obolibrary.org/obo/GO_0048286	denotes	alveolar
T7779	323-338	http://purl.obolibrary.org/obo/GO_0016032	denotes	viral infection
T7778	148-164	http://purl.obolibrary.org/obo/GO_0006955	denotes	immune responses
T7777	141-164	http://purl.obolibrary.org/obo/GO_0045824	denotes	innate immune responses
T7776	141-164	http://purl.obolibrary.org/obo/GO_0045089	denotes	innate immune responses
T7775	141-164	http://purl.obolibrary.org/obo/GO_0002218	denotes	innate immune responses
T7774	141-164	http://purl.obolibrary.org/obo/GO_0045088	denotes	innate immune responses
T7773	141-164	http://purl.obolibrary.org/obo/GO_0002227	denotes	innate immune responses
T7772	141-164	http://purl.obolibrary.org/obo/GO_0045087	denotes	innate immune responses
T7771	141-154	http://purl.obolibrary.org/obo/GO_0045087	denotes	innate immune
T7770	2279-2294	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression
T7769	1738-1753	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression
T7768	37-52	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T7788	2015-2018	http://purl.obolibrary.org/obo/GO_0004298	denotes	MCP
T7787	1952-1956	http://purl.obolibrary.org/obo/GO_0005138	denotes	IL-6
T7786	409-413	http://purl.obolibrary.org/obo/GO_0005138	denotes	IL-6
T20312	1300-1304	http://purl.obolibrary.org/obo/GO_0005138	denotes	IL-6
T20311	1200-1204	http://purl.obolibrary.org/obo/GO_0005138	denotes	IL-6
T20310	913-917	http://purl.obolibrary.org/obo/GO_0005138	denotes	IL-6

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T20315	1258-1262	http://purl.obolibrary.org/obo/GO_0005623	denotes	Cell
T20314	998-1002	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T20313	892-897	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7795	1507-1511	http://purl.obolibrary.org/obo/GO_0018995	denotes	host
T7794	2133-2138	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7793	2084-2089	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7792	1797-1802	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7791	1631-1636	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7790	564-569	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T7789	468-473	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

sentences

Id	Subject	Object	Predicate	Lexical cue
T20286	1432-1501	Sentence	denotes	Results are representative for 2 independent experiments. ***p<0,001.
T20285	1373-1431	Sentence	denotes	Error bars represent mean values (+/− SEM) of 2–3 samples.
T20284	1258-1372	Sentence	denotes	Cell culture supernatant was analyzed for IL-6 and IFNβ protein levels by ELISA and multiplexing technologies (D).
T20283	1200-1257	Sentence	denotes	IL-6 and IFNβ mRNA expression was determined by qPCR (C).
T20282	974-1199	Sentence	denotes	18 hours post infection cell culture supernatant was analyzed for TNF and IFNβ protein levels by ELISA and multiplexing technologies (B). (C–D) Alveolar macrophages were mock treated or infected with IAV (moi 1) for 18 hours.
T20281	845-973	Sentence	denotes	At different hours post infection (hours p.i.) cells were lysed and IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR (A).
T20280	754-844	Sentence	denotes	(A–B) BMDM isolated from A20myel-WT and A20myel-KO animals were infected with IAV (moi 1).
T20279	667-753	Sentence	denotes	A20 negatively regulates IAV-induced gene expression in BMDM and alveolar macrophages.
T7706	2166-2413	Sentence	denotes	Taken together these results demonstrate that A20 negatively regulates IAV-induced proinflammatory and antiviral gene expression in alveolar macrophages, consistent with the inhibitory effect of A20 seen on RIG-I-induced NF-κB and IRF3 activation.
T7705	1894-2165	Sentence	denotes	Expression and secretion of the proinflammatory cytokines IL-6 and TNF, the type-I IFN IFNβ and IFNα4 and the chemokines MCP-1 (ccl2) and KC (cxcl1) was significantly higher in IAV infected cells lacking A20 compared to infected wild type cells (figure 2C and figure S1).
T7704	1688-1893	Sentence	denotes	To test whether A20 directly controls IAV-induced gene expression in alveolar macrophages, we isolated these cells from lungs of A20myel-KO and control littermates and infected them in vitro with IAV X-47.
T7703	1502-1687	Sentence	denotes	Upon host infection with IAV, alveolar macrophages are an important source of cytokines and chemokines, attracting innate immune cells to the lung during the primary phase of infection.
T7702	487-622	Sentence	denotes	In accordance with these data, cell culture supernatant collected from these cells contained higher levels of TNF and IFNβ (figure 2B).
T7701	352-486	Sentence	denotes	Furthermore, A20myel-KO BMDM show enhanced expression of IL-6 and IFNβ mRNA after IAV infection compared to control cells (figure 2A).
T7700	231-351	Sentence	denotes	A20 mRNA levels were rapidly induced in wild type BMDM, but not in A20 deficient BMDM, upon viral infection (figure 2A).
T7699	61-230	Sentence	denotes	To investigate the role of A20 in the IAV-induced proinflammatory and antiviral innate immune responses, we infected A20 deficient and control BMDM with IAV X-47 (H3N2).
T7698	0-60	Sentence	denotes	A20 negatively regulates IAV-induced gene expression in BMDM
T93	0-60	Sentence	denotes	A20 negatively regulates IAV-induced gene expression in BMDM
T94	61-230	Sentence	denotes	To investigate the role of A20 in the IAV-induced proinflammatory and antiviral innate immune responses, we infected A20 deficient and control BMDM with IAV X-47 (H3N2).
T95	231-351	Sentence	denotes	A20 mRNA levels were rapidly induced in wild type BMDM, but not in A20 deficient BMDM, upon viral infection (figure 2A).
T96	352-486	Sentence	denotes	Furthermore, A20myel-KO BMDM show enhanced expression of IL-6 and IFNβ mRNA after IAV infection compared to control cells (figure 2A).
T97	487-622	Sentence	denotes	In accordance with these data, cell culture supernatant collected from these cells contained higher levels of TNF and IFNβ (figure 2B).
T98	623-753	Sentence	denotes	10.1371/journal.ppat.1002570.g002 Figure 2 A20 negatively regulates IAV-induced gene expression in BMDM and alveolar macrophages.
T99	754-844	Sentence	denotes	(A–B) BMDM isolated from A20myel-WT and A20myel-KO animals were infected with IAV (moi 1).
T100	845-973	Sentence	denotes	At different hours post infection (hours p.i.) cells were lysed and IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR (A).
T101	974-1199	Sentence	denotes	18 hours post infection cell culture supernatant was analyzed for TNF and IFNβ protein levels by ELISA and multiplexing technologies (B). (C–D) Alveolar macrophages were mock treated or infected with IAV (moi 1) for 18 hours.
T102	1200-1257	Sentence	denotes	IL-6 and IFNβ mRNA expression was determined by qPCR (C).
T103	1258-1372	Sentence	denotes	Cell culture supernatant was analyzed for IL-6 and IFNβ protein levels by ELISA and multiplexing technologies (D).
T104	1373-1431	Sentence	denotes	Error bars represent mean values (+/− SEM) of 2–3 samples.
T105	1432-1501	Sentence	denotes	Results are representative for 2 independent experiments. ***p<0,001.
T106	1502-1687	Sentence	denotes	Upon host infection with IAV, alveolar macrophages are an important source of cytokines and chemokines, attracting innate immune cells to the lung during the primary phase of infection.
T107	1688-1893	Sentence	denotes	To test whether A20 directly controls IAV-induced gene expression in alveolar macrophages, we isolated these cells from lungs of A20myel-KO and control littermates and infected them in vitro with IAV X-47.
T108	1894-2165	Sentence	denotes	Expression and secretion of the proinflammatory cytokines IL-6 and TNF, the type-I IFN IFNβ and IFNα4 and the chemokines MCP-1 (ccl2) and KC (cxcl1) was significantly higher in IAV infected cells lacking A20 compared to infected wild type cells (figure 2C and figure S1).
T109	2166-2413	Sentence	denotes	Taken together these results demonstrate that A20 negatively regulates IAV-induced proinflammatory and antiviral gene expression in alveolar macrophages, consistent with the inhibitory effect of A20 seen on RIG-I-induced NF-κB and IRF3 activation.

ICD10

Id	Subject	Object	Predicate	Lexical cue
T7785	323-338	http://purl.bioontology.org/ontology/ICD10/B34.9	denotes	viral infection

simple1

Id	Subject	Object	Predicate	Lexical cue
T20323	1309-1313	Protein	denotes	IFNβ
T20322	1300-1304	Protein	denotes	IL-6
T20321	1209-1213	Protein	denotes	IFNβ
T20320	1200-1204	Protein	denotes	IL-6
T20319	1048-1052	Protein	denotes	IFNβ
T20318	1040-1043	Protein	denotes	TNF
T20317	919-923	Protein	denotes	IFNβ
T20316	913-917	Protein	denotes	IL-6
T7809	2397-2401	Protein	denotes	IRF3
T7808	2373-2378	Protein	denotes	RIG-I
T7807	2036-2041	Protein	denotes	cxcl1
T7806	2032-2034	Protein	denotes	KC
T7805	2022-2026	Protein	denotes	ccl2
T7804	2015-2020	Protein	denotes	MCP-1
T7803	1990-1995	Protein	denotes	IFNα4
T7802	1981-1985	Protein	denotes	IFNβ
T7801	1961-1964	Protein	denotes	TNF
T7800	1952-1956	Protein	denotes	IL-6
T7799	605-609	Protein	denotes	IFNβ
T7798	597-600	Protein	denotes	TNF
T7797	418-422	Protein	denotes	IFNβ
T7796	409-413	Protein	denotes	IL-6

BioNLP16_DUT

Id	Subject	Object	Predicate	Lexical cue
T20725	1219-1229	Transcription	denotes	expression
T20724	937-947	Transcription	denotes	expression
T20723	1309-1313	Protein	denotes	IFNβ
T20722	1300-1304	Protein	denotes	IL-6
T20721	1209-1213	Protein	denotes	IFNβ
T20720	1200-1204	Protein	denotes	IL-6
T20719	1048-1052	Protein	denotes	IFNβ
T20718	1040-1043	Protein	denotes	TNF
T20717	919-923	Protein	denotes	IFNβ
T20716	913-917	Protein	denotes	IL-6
T8509	2379-2386	Positive_regulation	denotes	induced
T8508	2402-2412	Positive_regulation	denotes	activation
T8507	1894-1904	Gene_expression	denotes	Expression
T8506	1909-1918	Localization	denotes	secretion
T8505	587-593	Positive_regulation	denotes	levels
T8504	386-394	Positive_regulation	denotes	enhanced
T8503	395-405	Gene_expression	denotes	expression
T8502	2397-2401	Protein	denotes	IRF3
T8501	2373-2378	Protein	denotes	RIG-I
T8500	2015-2020	Protein	denotes	MCP-1
T8499	1990-1995	Protein	denotes	IFNα4
T8498	1981-1985	Protein	denotes	IFNβ
T8497	1961-1964	Protein	denotes	TNF
T8496	1952-1956	Protein	denotes	IL-6
T8495	2036-2041	Protein	denotes	cxcl1
T8494	2032-2034	Protein	denotes	KC
T8493	2022-2026	Protein	denotes	ccl2
T8492	605-609	Protein	denotes	IFNβ
T8491	597-600	Protein	denotes	TNF
T8490	418-422	Protein	denotes	IFNβ
T8489	409-413	Protein	denotes	IL-6
R6052	T8489	T8503	themeOf	IL-6,expression
R6053	T8490	T8503	themeOf	IFNβ,expression
R6054	T8491	T8505	themeOf	TNF,levels
R6057	T8494	T8506	themeOf	KC,secretion
R6059	T8495	T8506	themeOf	cxcl1,secretion
R6061	T8496	T8506	themeOf	IL-6,secretion
R6063	T8497	T8506	themeOf	TNF,secretion
R6069	T8500	T8506	themeOf	MCP-1,secretion
R6073	T8503	T8504	themeOf	expression,enhanced
R6074	T8503	T8504	themeOf	expression,enhanced
R6055	T8493	T8506	themeOf	ccl2,secretion
R6056	T8493	T8507	themeOf	ccl2,Expression
R6058	T8494	T8507	themeOf	KC,Expression
R6060	T8495	T8507	themeOf	cxcl1,Expression
R6062	T8496	T8507	themeOf	IL-6,Expression
R6064	T8497	T8507	themeOf	TNF,Expression
R6065	T8498	T8506	themeOf	IFNβ,secretion
R6066	T8498	T8507	themeOf	IFNβ,Expression
R6067	T8499	T8506	themeOf	IFNα4,secretion
R6068	T8499	T8507	themeOf	IFNα4,Expression
R6070	T8500	T8507	themeOf	MCP-1,Expression
R6071	T8501	T8509	themeOf	RIG-I,induced
R6072	T8502	T8508	themeOf	IRF3,activation
R15489	T20716	T20724	themeOf	IL-6,expression
R15490	T20717	T20724	themeOf	IFNβ,expression
R15491	T20720	T20725	themeOf	IL-6,expression
R15492	T20721	T20725	themeOf	IFNβ,expression

BioNLP16_Messiy

Id	Subject	Object	Predicate	Lexical cue
T20657	1219-1229	Transcription	denotes	expression
T20656	937-947	Transcription	denotes	expression
T20655	1309-1313	Protein	denotes	IFNβ
T20654	1300-1304	Protein	denotes	IL-6
T20653	1209-1213	Protein	denotes	IFNβ
T20652	1200-1204	Protein	denotes	IL-6
T20651	1048-1052	Protein	denotes	IFNβ
T20650	1040-1043	Protein	denotes	TNF
T20649	919-923	Protein	denotes	IFNβ
T20648	913-917	Protein	denotes	IL-6
T8374	2402-2412	Positive_regulation	denotes	activation
T8373	1894-1904	Gene_expression	denotes	Expression
T8372	1909-1918	Gene_expression	denotes	secretion
T8371	386-394	Positive_regulation	denotes	enhanced
T8370	395-405	Gene_expression	denotes	expression
T8369	2397-2401	Protein	denotes	IRF3
T8368	2373-2378	Protein	denotes	RIG-I
T8367	2015-2020	Protein	denotes	MCP-1
T8366	1990-1995	Protein	denotes	IFNα4
T8365	1981-1985	Protein	denotes	IFNβ
T8364	1961-1964	Protein	denotes	TNF
T8363	1952-1956	Protein	denotes	IL-6
T8362	2036-2041	Protein	denotes	cxcl1
T8361	2032-2034	Protein	denotes	KC
T8360	2022-2026	Protein	denotes	ccl2
T8359	605-609	Protein	denotes	IFNβ
T8358	597-600	Protein	denotes	TNF
T8357	418-422	Protein	denotes	IFNβ
T8356	409-413	Protein	denotes	IL-6
R5969	T8356	T8370	themeOf	IL-6,expression
R5970	T8357	T8370	themeOf	IFNβ,expression
R5971	T8360	T8372	themeOf	ccl2,secretion
R5972	T8360	T8373	themeOf	ccl2,Expression
R5973	T8361	T8372	themeOf	KC,secretion
R5974	T8361	T8373	themeOf	KC,Expression
R5975	T8362	T8372	themeOf	cxcl1,secretion
R5976	T8362	T8373	themeOf	cxcl1,Expression
R5977	T8363	T8372	themeOf	IL-6,secretion
R5978	T8363	T8373	themeOf	IL-6,Expression
R5979	T8364	T8373	themeOf	TNF,Expression
R5980	T8366	T8372	themeOf	IFNα4,secretion
R5981	T8367	T8372	themeOf	MCP-1,secretion
R5982	T8367	T8373	themeOf	MCP-1,Expression
R5983	T8369	T8374	themeOf	IRF3,activation
R5984	T8370	T8371	themeOf	expression,enhanced
R5985	T8370	T8371	themeOf	expression,enhanced
R15471	T20648	T20656	themeOf	IL-6,expression
R15472	T20652	T20657	themeOf	IL-6,expression
R15473	T20653	T20657	themeOf	IFNβ,expression

DLUT931

Id	Subject	Object	Predicate	Lexical cue
T20677	1219-1229	Transcription	denotes	expression
T20676	937-947	Transcription	denotes	expression
T20675	1309-1313	Protein	denotes	IFNβ
T20674	1300-1304	Protein	denotes	IL-6
T20673	1209-1213	Protein	denotes	IFNβ
T20672	1200-1204	Protein	denotes	IL-6
T20671	1048-1052	Protein	denotes	IFNβ
T20670	1040-1043	Protein	denotes	TNF
T20669	919-923	Protein	denotes	IFNβ
T20668	913-917	Protein	denotes	IL-6
T8394	2402-2412	Positive_regulation	denotes	activation
T8393	1909-1918	Localization	denotes	secretion
T8392	1894-1904	Gene_expression	denotes	Expression
T8391	580-586	Positive_regulation	denotes	higher
T8390	386-394	Positive_regulation	denotes	enhanced
T8389	395-405	Gene_expression	denotes	expression
T8388	2397-2401	Protein	denotes	IRF3
T8387	2373-2378	Protein	denotes	RIG-I
T8386	2015-2020	Protein	denotes	MCP-1
T8385	1990-1995	Protein	denotes	IFNα4
T8384	1981-1985	Protein	denotes	IFNβ
T8383	1961-1964	Protein	denotes	TNF
T8382	1952-1956	Protein	denotes	IL-6
T8381	2036-2041	Protein	denotes	cxcl1
T8380	2032-2034	Protein	denotes	KC
T8379	2022-2026	Protein	denotes	ccl2
T8378	605-609	Protein	denotes	IFNβ
T8377	597-600	Protein	denotes	TNF
T8376	418-422	Protein	denotes	IFNβ
T8375	409-413	Protein	denotes	IL-6
R5986	T8375	T8389	themeOf	IL-6,expression
R5987	T8376	T8389	themeOf	IFNβ,expression
R5988	T8377	T8391	themeOf	TNF,higher
R5989	T8378	T8391	themeOf	IFNβ,higher
R5990	T8379	T8392	themeOf	ccl2,Expression
R5991	T8379	T8393	themeOf	ccl2,secretion
R5992	T8380	T8392	themeOf	KC,Expression
R5993	T8380	T8393	themeOf	KC,secretion
R5994	T8381	T8392	themeOf	cxcl1,Expression
R5995	T8381	T8393	themeOf	cxcl1,secretion
R5996	T8382	T8392	themeOf	IL-6,Expression
R5997	T8382	T8393	themeOf	IL-6,secretion
R5998	T8383	T8392	themeOf	TNF,Expression
R5999	T8383	T8393	themeOf	TNF,secretion
R6000	T8384	T8392	themeOf	IFNβ,Expression
R6001	T8385	T8392	themeOf	IFNα4,Expression
R6002	T8386	T8392	themeOf	MCP-1,Expression
R6003	T8386	T8393	themeOf	MCP-1,secretion
R6004	T8388	T8394	themeOf	IRF3,activation
R6005	T8389	T8390	themeOf	expression,enhanced
R6006	T8389	T8390	themeOf	expression,enhanced
R15475	T20668	T20676	themeOf	IL-6,expression
R15476	T20669	T20676	themeOf	IFNβ,expression
R15477	T20672	T20677	themeOf	IL-6,expression
R15478	T20673	T20677	themeOf	IFNβ,expression

bionlp-st-ge-2016-test-ihmc

Id	Subject	Object	Predicate	Lexical cue
T20750	667-752	Regulation	denotes	A20 negatively regulates IAV-induced gene expression in BMDM and alveolar macrophages
T20749	913-968	Gene_expression	denotes	IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR
T20748	913-968	Transcription	denotes	IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR
T20747	1200-1256	Transcription	denotes	IL-6 and IFNβ mRNA expression was determined by qPCR (C)
T20746	1200-1256	Gene_expression	denotes	IL-6 and IFNβ mRNA expression was determined by qPCR (C)
T20745	928-931	Protein	denotes	A20
T20744	913-936	Protein	denotes	IL-6, IFNβ and A20 mRNA
T20743	667-670	Protein	denotes	A20
T20742	1300-1304	Protein	denotes	IL-6
T20741	1200-1218	Protein	denotes	IL-6 and IFNβ mRNA
T20740	919-923	Protein	denotes	IFNβ
T20739	892-897	Entity	denotes	cells
T20738	1200-1204	Protein	denotes	IL-6
T20737	1209-1213	Protein	denotes	IFNβ
T20736	1118-1138	Entity	denotes	Alveolar macrophages
T20735	1048-1067	Protein	denotes	IFNβ protein levels
T20734	1309-1313	Protein	denotes	IFNβ
T20733	1048-1052	Protein	denotes	IFNβ
T20732	913-917	Protein	denotes	IL-6
T20731	1309-1328	Protein	denotes	IFNβ protein levels
T20730	903-908	Protein	denotes	lysed
T20729	1040-1043	Protein	denotes	TNF
T20728	732-752	Entity	denotes	alveolar macrophages
T20727	1258-1282	Entity	denotes	Cell culture supernatant
T20726	974-1022	Entity	denotes	18 hours post infection cell culture supernatant
T8528	1977-1985	Protein	denotes	IFN IFNβ
T8527	131-165	Entity	denotes	antiviral innate immune responses,
T8526	2358-2364	Protein	denotes	of A20
T8525	2154-2163	Entity	denotes	figure S1
T8524	1791-1802	Entity	denotes	these cells
T8523	1532-1552	Entity	denotes	alveolar macrophages
T8522	1961-1965	Protein	denotes	TNF,
T8521	0-3	Protein	denotes	A20
T8520	298-311	Protein	denotes	A20 deficient
T8519	457-485	Entity	denotes	to control cells (figure 2A)
T8518	1977-1980	Protein	denotes	IFN
T8517	2098-2101	Protein	denotes	A20
T8516	178-191	Protein	denotes	A20 deficient
T8515	1942-1951	Protein	denotes	cytokines
T8514	2370-2392	Protein	denotes	on RIG-I-induced NF-κB
T8513	1594-1604	Protein	denotes	chemokines
T8512	2000-2020	Protein	denotes	the chemokines MCP-1
T8511	37-41	Protein	denotes	gene
T8510	597-600	Protein	denotes	TNF
T8558	2397-2412	Positive_regulation	denotes	IRF3 activation
T8557	395-427	Gene_expression	denotes	expression of IL-6 and IFNβ mRNA
T8556	395-427	Gene_expression	denotes	expression of IL-6 and IFNβ mRNA
T8555	2370-2392	Gene_expression	denotes	on RIG-I-induced NF-κB
T8554	2370-2392	Positive_regulation	denotes	on RIG-I-induced NF-κB
T8553	2331-2392	Regulation	denotes	with the inhibitory effect of A20 seen on RIG-I-induced NF-κB
T8552	1704-1777	Regulation	denotes	A20 directly controls IAV-induced gene expression in alveolar macrophages
T8551	2397-2401	Protein	denotes	IRF3
T8550	418-422	Protein	denotes	IFNβ
T8549	2022-2026	Protein	denotes	ccl2
T8548	2212-2215	Protein	denotes	A20
T8547	2036-2041	Protein	denotes	cxcl1
T8546	2269-2278	Entity	denotes	antiviral
T8545	231-234	Protein	denotes	A20
T8544	1757-1777	Entity	denotes	alveolar macrophages
T8543	605-621	Protein	denotes	IFNβ (figure 2B)
T8542	2000-2020	Protein	denotes	the chemokines MCP-1
T8541	2298-2318	Entity	denotes	alveolar macrophages
T8540	1990-1995	Protein	denotes	IFNα4
T8539	85-110	Protein	denotes	of A20 in the IAV-induced
T8538	558-569	Entity	denotes	these cells
T8537	1952-1956	Protein	denotes	IL-6
T8536	418-427	Protein	denotes	IFNβ mRNA
T8535	2032-2042	Protein	denotes	KC (cxcl1)
T8534	2111-2164	Entity	denotes	to infected wild type cells (figure 2C and figure S1)
T8533	2373-2386	Protein	denotes	RIG-I-induced
T8532	409-413	Protein	denotes	IL-6
T8531	1704-1707	Protein	denotes	A20
T8530	224-228	Entity	denotes	H3N2
T8529	1580-1589	Protein	denotes	cytokines
R6075	T8514	T8553	themeOf	on RIG-I-induced NF-κB,with the inhibitory effect of A20 seen on RIG-I-induced NF-κB
R6076	T8514	T8554	themeOf	on RIG-I-induced NF-κB,on RIG-I-induced NF-κB
R6077	T8514	T8555	themeOf	on RIG-I-induced NF-κB,on RIG-I-induced NF-κB
R6078	T8526	T8553	causeOf	of A20,with the inhibitory effect of A20 seen on RIG-I-induced NF-κB
R6079	T8531	T8552	causeOf	A20,A20 directly controls IAV-induced gene expression in alveolar macrophages
R6080	T8532	T8557	themeOf	IL-6,expression of IL-6 and IFNβ mRNA
R6081	T8533	T8554	causeOf	RIG-I-induced,on RIG-I-induced NF-κB
R6082	T8536	T8556	themeOf	IFNβ mRNA,expression of IL-6 and IFNβ mRNA
R15493	T20741	T20746	themeOf	IL-6 and IFNβ mRNA,IL-6 and IFNβ mRNA expression was determined by qPCR (C)
R15494	T20741	T20747	themeOf	IL-6 and IFNβ mRNA,IL-6 and IFNβ mRNA expression was determined by qPCR (C)
R15495	T20743	T20750	causeOf	A20,A20 negatively regulates IAV-induced gene expression in BMDM and alveolar macrophages
R15496	T20744	T20748	themeOf	"IL-6, IFNβ and A20 mRNA","IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR"
R15497	T20744	T20749	themeOf	"IL-6, IFNβ and A20 mRNA","IL-6, IFNβ and A20 mRNA expression was analyzed by qPCR"
R6083	T8551	T8558	themeOf	IRF3,IRF3 activation

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T20490	758-759	-RRB-	denotes	)
T20489	757-758	NNP	denotes	B
T20488	755-756	DT	denotes	A
T20487	754-755	-LRB-	denotes	(
T20486	752-753	.	denotes	.
T20485	741-752	NNS	denotes	macrophages
T20484	732-740	JJ	denotes	alveolar
T20483	728-731	CC	denotes	and
T20482	723-727	NNP	denotes	BMDM
T20481	720-722	IN	denotes	in
T20480	709-719	NN	denotes	expression
T20479	704-708	NN	denotes	gene
T20478	692-703	JJ	denotes	IAV-induced
T20477	682-691	VBZ	denotes	regulates
T20476	671-681	RB	denotes	negatively
T20475	667-670	CD	denotes	A20
T20641	1500-1501	.	denotes	.
T20640	1495-1500	CD	denotes	0,001
T20639	1494-1495	FW	denotes	<
T20638	1493-1494	FW	denotes	p
T20637	1490-1493	FW	denotes	***
T20636	1488-1489	.	denotes	.
T20635	1477-1488	NNS	denotes	experiments
T20634	1465-1476	JJ	denotes	independent
T20633	1463-1464	CD	denotes	2
T20632	1459-1462	IN	denotes	for
T20631	1444-1458	JJ	denotes	representative
T20630	1440-1443	VBP	denotes	are
T20629	1432-1439	NNS	denotes	Results
T20628	1430-1431	.	denotes	.
T20627	1423-1430	NNS	denotes	samples
T20626	1421-1422	CD	denotes	3
T20625	1419-1420	CD	denotes	2
T20624	1416-1418	IN	denotes	of
T20623	1414-1415	-RRB-	denotes	)
T20622	1411-1414	NNP	denotes	SEM
T20621	1409-1410	FW	denotes	−
T20620	1408-1409	FW	denotes	/
T20619	1407-1408	FW	denotes	+
T20618	1406-1407	-LRB-	denotes	(
T20617	1399-1405	NNS	denotes	values
T20616	1394-1398	JJ	denotes	mean
T20615	1384-1393	VBP	denotes	represent
T20614	1379-1383	NNS	denotes	bars
T20613	1373-1378	NN	denotes	Error
T20612	1371-1372	.	denotes	.
T20611	1370-1371	-RRB-	denotes	)
T20610	1369-1370	NNP	denotes	D
T20609	1368-1369	-LRB-	denotes	(
T20608	1355-1367	NNS	denotes	technologies
T20607	1342-1354	VBG	denotes	multiplexing
T20606	1338-1341	CC	denotes	and
T20605	1332-1337	NNP	denotes	ELISA
T20604	1329-1331	IN	denotes	by
T20603	1322-1328	NNS	denotes	levels
T20602	1314-1321	NN	denotes	protein
T20601	1309-1313	NNP	denotes	IFNβ
T20600	1305-1308	CC	denotes	and
T20599	1300-1304	NNP	denotes	IL-6
T20598	1296-1299	IN	denotes	for
T20597	1287-1295	VBN	denotes	analyzed
T20596	1283-1286	VBD	denotes	was
T20595	1271-1282	NN	denotes	supernatant
T20594	1263-1270	NN	denotes	culture
T20593	1258-1262	NNP	denotes	Cell
T20592	1256-1257	.	denotes	.
T20591	1255-1256	-RRB-	denotes	)
T20590	1254-1255	NNP	denotes	C
T20589	1253-1254	-LRB-	denotes	(
T20588	1248-1252	NNP	denotes	qPCR
T20587	1245-1247	IN	denotes	by
T20586	1234-1244	VBN	denotes	determined
T20585	1230-1233	VBD	denotes	was
T20584	1219-1229	NN	denotes	expression
T20583	1214-1218	NNP	denotes	mRNA
T20582	1209-1213	NNP	denotes	IFNβ
T20581	1205-1208	CC	denotes	and
T20580	1200-1204	NN	denotes	IL-6
T20579	1198-1199	.	denotes	.
T20578	1193-1198	NNS	denotes	hours
T20577	1190-1192	CD	denotes	18
T20576	1186-1189	IN	denotes	for
T20575	1184-1185	-RRB-	denotes	)
T20574	1183-1184	LS	denotes	1
T20573	1179-1182	FW	denotes	moi
T20572	1178-1179	-LRB-	denotes	(
T20571	1174-1177	NNP	denotes	IAV
T20570	1169-1173	IN	denotes	with
T20569	1160-1168	VBN	denotes	infected
T20568	1157-1159	CC	denotes	or
T20567	1149-1156	VBN	denotes	treated
T20566	1144-1148	JJ	denotes	mock
T20565	1139-1143	VBD	denotes	were
T20564	1127-1138	NNS	denotes	macrophages
T20563	1118-1126	NNP	denotes	Alveolar
T20562	1116-1117	-RRB-	denotes	)
T20561	1115-1116	NNP	denotes	D
T20560	1113-1114	$	denotes	C
T20559	1112-1113	-LRB-	denotes	(
T20558	1110-1111	.	denotes	.
T20557	1109-1110	-RRB-	denotes	)
T20556	1108-1109	NNP	denotes	B
T20555	1107-1108	-LRB-	denotes	(
T20554	1094-1106	NNS	denotes	technologies
T20553	1081-1093	VBG	denotes	multiplexing
T20552	1077-1080	CC	denotes	and
T20551	1071-1076	NNP	denotes	ELISA
T20550	1068-1070	IN	denotes	by
T20549	1061-1067	NNS	denotes	levels
T20548	1053-1060	NN	denotes	protein
T20547	1048-1052	NNP	denotes	IFNβ
T20546	1044-1047	CC	denotes	and
T20545	1040-1043	NNP	denotes	TNF
T20544	1036-1039	IN	denotes	for
T20543	1027-1035	VBN	denotes	analyzed
T20542	1023-1026	VBD	denotes	was
T20541	1011-1022	NN	denotes	supernatant
T20540	1003-1010	NN	denotes	culture
T20539	998-1002	NN	denotes	cell
T20538	988-997	NN	denotes	infection
T20537	983-987	NN	denotes	post
T20536	977-982	NNS	denotes	hours
T20535	974-976	CD	denotes	18
T20534	972-973	.	denotes	.
T20533	971-972	-RRB-	denotes	)
T20532	970-971	NNP	denotes	A
T20531	969-970	-LRB-	denotes	(
T20530	964-968	NNP	denotes	qPCR
T20529	961-963	IN	denotes	by
T20528	952-960	VBN	denotes	analyzed
T20527	948-951	VBD	denotes	was
T20526	937-947	NN	denotes	expression
T20525	932-936	NNP	denotes	mRNA
T20524	928-931	NNP	denotes	A20
T20523	924-927	CC	denotes	and
T20522	919-923	NNP	denotes	IFNβ
T20521	917-918	,	denotes	,
T20520	913-917	NNP	denotes	IL-6
T20519	909-912	CC	denotes	and
T20518	903-908	VBN	denotes	lysed
T20517	898-902	VBD	denotes	were
T20516	892-897	NNS	denotes	cells
T20515	890-891	-RRB-	denotes	)
T20514	886-890	VBP	denotes	p.i.
T20513	880-885	NNS	denotes	hours
T20512	879-880	-LRB-	denotes	(
T20511	869-878	NN	denotes	infection
T20510	864-868	NN	denotes	post
T20509	858-863	NNS	denotes	hours
T20508	848-857	JJ	denotes	different
T20507	845-847	IN	denotes	At
T20506	843-844	.	denotes	.
T20505	842-843	-RRB-	denotes	)
T20504	841-842	LS	denotes	1
T20503	837-840	FW	denotes	moi
T20502	836-837	-LRB-	denotes	(
T20501	832-835	NNP	denotes	IAV
T20500	827-831	IN	denotes	with
T20499	818-826	VBN	denotes	infected
T20498	813-817	VBD	denotes	were
T20497	805-812	NNS	denotes	animals
T20496	794-804	JJ	denotes	A20myel-KO
T20495	790-793	CC	denotes	and
T20494	779-789	JJ	denotes	A20myel-WT
T20493	774-778	IN	denotes	from
T20492	765-773	VBD	denotes	isolated
T20491	760-764	NNP	denotes	BMDM
T8341	2412-2413	.	denotes	.
T8340	2402-2412	NN	denotes	activation
T8339	2397-2401	JJ	denotes	IRF3
T8338	2393-2396	CC	denotes	and
T8337	2387-2392	NN	denotes	NF-κB
T8336	2373-2386	JJ	denotes	RIG-I-induced
T8335	2370-2372	IN	denotes	on
T8334	2365-2369	VBN	denotes	seen
T8333	2361-2364	NNP	denotes	A20
T8332	2358-2360	IN	denotes	of
T8331	2351-2357	NN	denotes	effect
T8330	2340-2350	JJ	denotes	inhibitory
T8329	2336-2339	DT	denotes	the
T8328	2331-2335	IN	denotes	with
T8327	2320-2330	JJ	denotes	consistent
T8326	2318-2319	,	denotes	,
T8325	2307-2318	NNS	denotes	macrophages
T8324	2298-2306	JJ	denotes	alveolar
T8323	2295-2297	IN	denotes	in
T8322	2284-2294	NN	denotes	expression
T8321	2279-2283	NN	denotes	gene
T8320	2269-2278	JJ	denotes	antiviral
T8319	2265-2268	CC	denotes	and
T8318	2249-2264	JJ	denotes	proinflammatory
T8317	2237-2248	JJ	denotes	IAV-induced
T8316	2227-2236	VBZ	denotes	regulates
T8315	2216-2226	RB	denotes	negatively
T8314	2212-2215	CD	denotes	A20
T8313	2207-2211	IN	denotes	that
T8241	1808-1813	NNS	denotes	lungs
T8240	1803-1807	IN	denotes	from
T8239	1797-1802	NNS	denotes	cells
T8238	1791-1796	DT	denotes	these
T8237	1782-1790	VBD	denotes	isolated
T8236	1779-1781	PRP	denotes	we
T8235	1777-1778	,	denotes	,
T8234	1766-1777	NNS	denotes	macrophages
T8233	1757-1765	JJ	denotes	alveolar
T8232	1754-1756	IN	denotes	in
T8231	1743-1753	NN	denotes	expression
T8230	1738-1742	NN	denotes	gene
T8229	1726-1737	JJ	denotes	IAV-induced
T8228	1717-1725	VBZ	denotes	controls
T8227	1708-1716	RB	denotes	directly
T8226	1704-1707	NNP	denotes	A20
T8225	1696-1703	IN	denotes	whether
T8224	1691-1695	VB	denotes	test
T8223	1688-1690	TO	denotes	To
T8222	1686-1687	.	denotes	.
T8221	1677-1686	NN	denotes	infection
T8220	1674-1676	IN	denotes	of
T8219	1668-1673	NN	denotes	phase
T8218	1660-1667	JJ	denotes	primary
T8217	1656-1659	DT	denotes	the
T8216	1649-1655	IN	denotes	during
T8215	1644-1648	NN	denotes	lung
T8214	1640-1643	DT	denotes	the
T8213	1637-1639	TO	denotes	to
T8212	1631-1636	NNS	denotes	cells
T8211	1624-1630	JJ	denotes	immune
T8210	1617-1623	JJ	denotes	innate
T8209	1606-1616	VBG	denotes	attracting
T8208	1604-1605	,	denotes	,
T8207	1594-1604	NNS	denotes	chemokines
T8206	1590-1593	CC	denotes	and
T8205	1580-1589	NNS	denotes	cytokines
T8204	1577-1579	IN	denotes	of
T8203	1570-1576	NN	denotes	source
T8202	1560-1569	JJ	denotes	important
T8201	1557-1559	DT	denotes	an
T8200	1553-1556	VBP	denotes	are
T8199	1541-1552	NNS	denotes	macrophages
T8198	1532-1540	JJ	denotes	alveolar
T8197	1530-1531	,	denotes	,
T8196	1527-1530	NNP	denotes	IAV
T8195	1522-1526	IN	denotes	with
T8194	1512-1521	NN	denotes	infection
T8193	1507-1511	NN	denotes	host
T8192	1502-1506	IN	denotes	Upon
T8191	621-622	.	denotes	.
T8190	620-621	-RRB-	denotes	)
T8189	618-620	NN	denotes	2B
T8188	611-617	NN	denotes	figure
T8187	610-611	-LRB-	denotes	(
T8186	605-609	NNP	denotes	IFNβ
T8185	601-604	CC	denotes	and
T8184	597-600	NNP	denotes	TNF
T8183	594-596	IN	denotes	of
T8182	587-593	NNS	denotes	levels
T8181	580-586	JJR	denotes	higher
T8180	570-579	VBD	denotes	contained
T8179	564-569	NNS	denotes	cells
T8178	558-563	DT	denotes	these
T8177	553-557	IN	denotes	from
T8176	543-552	VBN	denotes	collected
T8175	531-542	JJ	denotes	supernatant
T8174	523-530	NN	denotes	culture
T8173	518-522	NN	denotes	cell
T8172	516-517	,	denotes	,
T8171	512-516	NNS	denotes	data
T8170	506-511	DT	denotes	these
T8169	501-505	IN	denotes	with
T8168	490-500	NN	denotes	accordance
T8167	487-489	IN	denotes	In
T8166	485-486	.	denotes	.
T8165	484-485	-RRB-	denotes	)
T8164	482-484	NN	denotes	2A
T8163	475-481	NN	denotes	figure
T8162	474-475	-LRB-	denotes	(
T8161	468-473	NNS	denotes	cells
T8160	460-467	VB	denotes	control
T8159	457-459	TO	denotes	to
T8158	448-456	VBN	denotes	compared
T8157	438-447	NN	denotes	infection
T8156	434-437	NNP	denotes	IAV
T8155	428-433	IN	denotes	after
T8154	423-427	NNP	denotes	mRNA
T8153	418-422	NNP	denotes	IFNβ
T8152	414-417	CC	denotes	and
T8151	409-413	NNP	denotes	IL-6
T8150	406-408	IN	denotes	of
T8149	395-405	NN	denotes	expression
T8148	386-394	JJ	denotes	enhanced
T8147	381-385	NN	denotes	show
T8146	376-380	NNP	denotes	BMDM
T8145	365-375	JJ	denotes	A20myel-KO
T8144	363-364	,	denotes	,
T8143	352-363	RB	denotes	Furthermore
T8142	350-351	.	denotes	.
T8141	349-350	-RRB-	denotes	)
T8140	347-349	NN	denotes	2A
T8139	340-346	NN	denotes	figure
T8138	339-340	-LRB-	denotes	(
T8137	329-338	NN	denotes	infection
T8136	323-328	JJ	denotes	viral
T8135	318-322	IN	denotes	upon
T8134	316-317	,	denotes	,
T8133	312-316	NNP	denotes	BMDM
T8132	302-311	JJ	denotes	deficient
T8131	298-301	CD	denotes	A20
T8130	295-297	IN	denotes	in
T8129	291-294	RB	denotes	not
T8128	287-290	CC	denotes	but
T8127	285-286	,	denotes	,
T8126	281-285	NNP	denotes	BMDM
T8125	276-280	NN	denotes	type
T8124	271-275	JJ	denotes	wild
T8123	268-270	IN	denotes	in
T8122	260-267	VBN	denotes	induced
T8121	252-259	RB	denotes	rapidly
T8120	247-251	VBD	denotes	were
T8119	240-246	NNS	denotes	levels
T8118	235-239	NNP	denotes	mRNA
T8117	231-234	CD	denotes	A20
T8116	229-230	.	denotes	.
T8115	228-229	-RRB-	denotes	)
T8114	224-228	NNP	denotes	H3N2
T8113	223-224	-LRB-	denotes	(
T8112	218-222	NNP	denotes	X-47
T8111	214-217	NNP	denotes	IAV
T8110	209-213	IN	denotes	with
T8109	204-208	NNP	denotes	BMDM
T8108	196-203	NN	denotes	control
T8107	192-195	CC	denotes	and
T8106	182-191	NN	denotes	deficient
T8105	178-181	NNP	denotes	A20
T8104	169-177	VBD	denotes	infected
T8103	166-168	PRP	denotes	we
T8102	164-165	,	denotes	,
T8101	155-164	NNS	denotes	responses
T8100	148-154	JJ	denotes	immune
T8099	141-147	NN	denotes	innate
T8098	131-140	JJ	denotes	antiviral
T8097	127-130	CC	denotes	and
T8096	111-126	JJ	denotes	proinflammatory
T8095	99-110	JJ	denotes	IAV-induced
T8094	95-98	DT	denotes	the
T8093	92-94	IN	denotes	in
T8092	88-91	NNP	denotes	A20
T8091	85-87	IN	denotes	of
T8090	80-84	NN	denotes	role
T8089	76-79	DT	denotes	the
T8088	64-75	VB	denotes	investigate
T8087	61-63	TO	denotes	To
T8086	56-60	NNP	denotes	BMDM
T8085	53-55	IN	denotes	in
T8084	42-52	NN	denotes	expression
T8083	37-41	NN	denotes	gene
T8082	25-36	JJ	denotes	IAV-induced
T8081	15-24	VBZ	denotes	regulates
T8080	4-14	RB	denotes	negatively
T8079	0-3	CD	denotes	A20
T8312	2195-2206	VBP	denotes	demonstrate
T8311	2187-2194	NNS	denotes	results
T8310	2181-2186	DT	denotes	these
T8309	2172-2180	RB	denotes	together
T8308	2166-2171	VBN	denotes	Taken
T8307	2164-2165	.	denotes	.
T8306	2163-2164	-RRB-	denotes	)
T8305	2161-2163	CD	denotes	S1
T8304	2154-2160	NN	denotes	figure
T8303	2150-2153	CC	denotes	and
T8302	2147-2149	NN	denotes	2C
T8301	2140-2146	NN	denotes	figure
T8300	2139-2140	-LRB-	denotes	(
T8299	2133-2138	NNS	denotes	cells
T8298	2128-2132	NN	denotes	type
T8297	2123-2127	JJ	denotes	wild
T8296	2114-2122	JJ	denotes	infected
T8295	2111-2113	TO	denotes	to
T8294	2102-2110	VBN	denotes	compared
T8293	2098-2101	NNP	denotes	A20
T8292	2090-2097	VBG	denotes	lacking
T8291	2084-2089	NNS	denotes	cells
T8290	2075-2083	JJ	denotes	infected
T8289	2071-2074	NNP	denotes	IAV
T8288	2068-2070	IN	denotes	in
T8287	2061-2067	JJR	denotes	higher
T8286	2047-2060	RB	denotes	significantly
T8285	2043-2046	VBD	denotes	was
T8284	2041-2042	-RRB-	denotes	)
T8283	2036-2041	CD	denotes	cxcl1
T8282	2035-2036	-LRB-	denotes	(
T8281	2032-2034	NNP	denotes	KC
T8280	2028-2031	CC	denotes	and
T8279	2026-2027	-RRB-	denotes	)
T8278	2022-2026	CD	denotes	ccl2
T8277	2021-2022	-LRB-	denotes	(
T8276	2015-2020	NNP	denotes	MCP-1
T8275	2004-2014	NNS	denotes	chemokines
T8274	2000-2003	DT	denotes	the
T8273	1996-1999	CC	denotes	and
T8272	1990-1995	NNP	denotes	IFNα4
T8271	1986-1989	CC	denotes	and
T8270	1981-1985	NNP	denotes	IFNβ
T8269	1977-1980	NNP	denotes	IFN
T8268	1970-1976	NNP	denotes	type-I
T8267	1966-1969	DT	denotes	the
T8266	1964-1965	,	denotes	,
T8265	1961-1964	NNP	denotes	TNF
T8264	1957-1960	CC	denotes	and
T8263	1952-1956	NNP	denotes	IL-6
T8262	1942-1951	NNS	denotes	cytokines
T8261	1926-1941	JJ	denotes	proinflammatory
T8260	1922-1925	DT	denotes	the
T8259	1919-1921	IN	denotes	of
T8258	1909-1918	NN	denotes	secretion
T8257	1905-1908	CC	denotes	and
T8256	1894-1904	NN	denotes	Expression
T8255	1892-1893	.	denotes	.
T8254	1888-1892	NNP	denotes	X-47
T8253	1884-1887	NNP	denotes	IAV
T8252	1879-1883	IN	denotes	with
T8251	1873-1878	NN	denotes	vitro
T8250	1870-1872	IN	denotes	in
T8249	1865-1869	PRP	denotes	them
T8248	1856-1864	VBD	denotes	infected
T8247	1852-1855	CC	denotes	and
T8246	1840-1851	NNS	denotes	littermates
T8245	1832-1839	NN	denotes	control
T8244	1828-1831	CC	denotes	and
T8243	1817-1827	JJ	denotes	A20myel-KO
T8242	1814-1816	IN	denotes	of
R5706	T8079	T8081	nsubj	A20,regulates
R5707	T8080	T8081	advmod	negatively,regulates
R5708	T8081	T8104	ccomp	regulates,infected
R5709	T8082	T8084	amod	IAV-induced,expression
R5710	T8083	T8084	compound	gene,expression
R5711	T8084	T8081	dobj	expression,regulates
R5712	T8085	T8084	prep	in,expression
R5713	T8086	T8085	pobj	BMDM,in
R5714	T8087	T8088	aux	To,investigate
R5715	T8088	T8081	advcl	investigate,regulates
R5716	T8089	T8090	det	the,role
R5717	T8090	T8088	dobj	role,investigate
R5718	T8091	T8090	prep	of,role
R5719	T8092	T8091	pobj	A20,of
R5720	T8093	T8090	prep	in,role
R5721	T8094	T8101	det	the,responses
R5722	T8095	T8101	amod	IAV-induced,responses
R5723	T8096	T8095	conj	proinflammatory,IAV-induced
R5724	T8097	T8096	cc	and,proinflammatory
R5725	T8098	T8096	conj	antiviral,proinflammatory
R5726	T8099	T8101	amod	innate,responses
R5727	T8100	T8101	amod	immune,responses
R5728	T8101	T8093	pobj	responses,in
R5729	T8102	T8104	punct	",",infected
R5730	T8103	T8104	nsubj	we,infected
R5731	T8104	T8104	ROOT	infected,infected
R5732	T8105	T8106	compound	A20,deficient
R5733	T8106	T8109	nmod	deficient,BMDM
R5734	T8107	T8106	cc	and,deficient
R5735	T8108	T8106	conj	control,deficient
R5736	T8109	T8104	dobj	BMDM,infected
R5737	T8110	T8104	prep	with,infected
R5738	T8111	T8112	compound	IAV,X-47
R5739	T8112	T8110	pobj	X-47,with
R5740	T8113	T8112	punct	(,X-47
R5741	T8114	T8112	appos	H3N2,X-47
R5742	T8115	T8112	punct	),X-47
R5743	T8116	T8104	punct	.,infected
R5744	T8117	T8119	nummod	A20,levels
R5745	T8118	T8119	compound	mRNA,levels
R5746	T8119	T8122	nsubjpass	levels,induced
R5747	T8120	T8122	auxpass	were,induced
R5748	T8121	T8122	advmod	rapidly,induced
R5749	T8122	T8122	ROOT	induced,induced
R5750	T8123	T8122	prep	in,induced
R5751	T8124	T8125	amod	wild,type
R5752	T8125	T8126	compound	type,BMDM
R5753	T8126	T8123	pobj	BMDM,in
R5754	T8127	T8122	punct	",",induced
R5755	T8128	T8122	cc	but,induced
R5756	T8129	T8130	neg	not,in
R5757	T8130	T8122	conj	in,induced
R5758	T8131	T8130	pobj	A20,in
R5759	T8132	T8133	amod	deficient,BMDM
R5760	T8133	T8130	conj	BMDM,in
R5761	T8134	T8135	punct	",",upon
R5762	T8135	T8133	prep	upon,BMDM
R5763	T8136	T8137	amod	viral,infection
R5764	T8137	T8135	pobj	infection,upon
R5765	T8138	T8140	punct	(,2A
R5766	T8139	T8140	compound	figure,2A
R5767	T8140	T8137	appos	2A,infection
R5768	T8141	T8140	punct	),2A
R5769	T8142	T8122	punct	.,induced
R5770	T8143	T8147	advmod	Furthermore,show
R5771	T8144	T8147	punct	",",show
R5772	T8145	T8147	compound	A20myel-KO,show
R5773	T8146	T8147	compound	BMDM,show
R5774	T8147	T8147	ROOT	show,show
R5775	T8148	T8149	amod	enhanced,expression
R5776	T8149	T8147	dobj	expression,show
R5777	T8150	T8149	prep	of,expression
R5778	T8151	T8150	pobj	IL-6,of
R5779	T8152	T8151	cc	and,IL-6
R5780	T8153	T8154	compound	IFNβ,mRNA
R5781	T8154	T8147	appos	mRNA,show
R5782	T8155	T8158	mark	after,compared
R5783	T8156	T8157	compound	IAV,infection
R5784	T8157	T8158	nsubj	infection,compared
R5785	T8158	T8147	advcl	compared,show
R5786	T8159	T8160	aux	to,control
R5787	T8160	T8158	xcomp	control,compared
R5788	T8161	T8160	dobj	cells,control
R5789	T8162	T8161	punct	(,cells
R5790	T8163	T8164	compound	figure,2A
R5791	T8164	T8161	appos	2A,cells
R5792	T8165	T8161	punct	),cells
R5793	T8166	T8147	punct	.,show
R5794	T8167	T8180	prep	In,contained
R5795	T8168	T8167	pobj	accordance,In
R5796	T8169	T8168	prep	with,accordance
R5797	T8170	T8171	det	these,data
R5798	T8171	T8169	pobj	data,with
R5799	T8172	T8180	punct	",",contained
R5800	T8173	T8174	compound	cell,culture
R5801	T8174	T8175	compound	culture,supernatant
R5802	T8175	T8180	nsubj	supernatant,contained
R5803	T8176	T8175	acl	collected,supernatant
R5804	T8177	T8176	prep	from,collected
R5805	T8178	T8179	det	these,cells
R5806	T8179	T8177	pobj	cells,from
R5807	T8180	T8180	ROOT	contained,contained
R5808	T8181	T8182	amod	higher,levels
R5809	T8182	T8180	dobj	levels,contained
R5810	T8183	T8182	prep	of,levels
R5811	T8184	T8183	pobj	TNF,of
R5812	T8185	T8184	cc	and,TNF
R5813	T8186	T8184	conj	IFNβ,TNF
R5814	T8187	T8189	punct	(,2B
R5815	T8188	T8189	compound	figure,2B
R5816	T8189	T8186	appos	2B,IFNβ
R5817	T8190	T8186	punct	),IFNβ
R5827	T8200	T8200	ROOT	are,are
R5828	T8201	T8203	det	an,source
R5829	T8202	T8203	amod	important,source
R5830	T8203	T8200	attr	source,are
R5831	T8204	T8203	prep	of,source
R5832	T8205	T8204	pobj	cytokines,of
R5833	T8206	T8205	cc	and,cytokines
R5834	T8207	T8205	conj	chemokines,cytokines
R5835	T8208	T8200	punct	",",are
R5836	T8209	T8200	advcl	attracting,are
R5837	T8210	T8212	amod	innate,cells
R5838	T8211	T8212	amod	immune,cells
R5839	T8212	T8209	dobj	cells,attracting
R5840	T8213	T8209	prep	to,attracting
R5841	T8214	T8215	det	the,lung
R5842	T8215	T8213	pobj	lung,to
R5843	T8216	T8209	prep	during,attracting
R5844	T8217	T8219	det	the,phase
R5845	T8218	T8219	amod	primary,phase
R5846	T8219	T8216	pobj	phase,during
R5847	T8220	T8219	prep	of,phase
R5848	T8221	T8220	pobj	infection,of
R5849	T8222	T8200	punct	.,are
R5850	T8223	T8224	aux	To,test
R5851	T8224	T8237	advcl	test,isolated
R5852	T8225	T8228	mark	whether,controls
R5853	T8226	T8228	nsubj	A20,controls
R5854	T8227	T8228	advmod	directly,controls
R5855	T8228	T8237	advcl	controls,isolated
R5856	T8229	T8231	amod	IAV-induced,expression
R5857	T8230	T8231	compound	gene,expression
R5858	T8231	T8228	dobj	expression,controls
R5859	T8232	T8231	prep	in,expression
R5860	T8233	T8234	amod	alveolar,macrophages
R5861	T8234	T8232	pobj	macrophages,in
R5862	T8235	T8237	punct	",",isolated
R5863	T8236	T8237	nsubj	we,isolated
R5864	T8237	T8237	ROOT	isolated,isolated
R5865	T8238	T8239	det	these,cells
R5866	T8239	T8237	dobj	cells,isolated
R5867	T8240	T8237	prep	from,isolated
R5868	T8241	T8240	pobj	lungs,from
R5869	T8242	T8241	prep	of,lungs
R5870	T8243	T8242	pobj	A20myel-KO,of
R5871	T8244	T8243	cc	and,A20myel-KO
R5872	T8245	T8243	conj	control,A20myel-KO
R5873	T8246	T8243	conj	littermates,A20myel-KO
R5874	T8247	T8237	cc	and,isolated
R5875	T8248	T8237	conj	infected,isolated
R5876	T8249	T8248	dobj	them,infected
R5877	T8250	T8248	prep	in,infected
R5878	T8251	T8250	pobj	vitro,in
R5879	T8252	T8248	prep	with,infected
R5880	T8253	T8254	compound	IAV,X-47
R5881	T8254	T8252	pobj	X-47,with
R5882	T8255	T8237	punct	.,isolated
R5883	T8256	T8285	nsubj	Expression,was
R5884	T8257	T8256	cc	and,Expression
R5885	T8258	T8256	conj	secretion,Expression
R5886	T8259	T8258	prep	of,secretion
R5887	T8260	T8262	det	the,cytokines
R5888	T8261	T8262	amod	proinflammatory,cytokines
R5889	T8262	T8263	compound	cytokines,IL-6
R5890	T8263	T8259	pobj	IL-6,of
R5891	T8264	T8263	cc	and,IL-6
R5892	T8265	T8263	conj	TNF,IL-6
R5893	T8266	T8265	punct	",",TNF
R5894	T8267	T8270	det	the,IFNβ
R5895	T8268	T8270	compound	type-I,IFNβ
R5896	T8269	T8270	compound	IFN,IFNβ
R5897	T8270	T8265	conj	IFNβ,TNF
R5898	T8271	T8270	cc	and,IFNβ
R5899	T8272	T8270	conj	IFNα4,IFNβ
R5900	T8273	T8272	cc	and,IFNα4
R5901	T8274	T8275	det	the,chemokines
R5902	T8275	T8272	conj	chemokines,IFNα4
R5903	T8276	T8285	nsubj	MCP-1,was
R5904	T8277	T8278	punct	(,ccl2
R5905	T8278	T8276	parataxis	ccl2,MCP-1
R5906	T8279	T8278	punct	),ccl2
R5907	T8280	T8276	cc	and,MCP-1
R5908	T8281	T8276	conj	KC,MCP-1
R5909	T8282	T8283	punct	(,cxcl1
R5910	T8283	T8276	appos	cxcl1,MCP-1
R5911	T8284	T8276	punct	),MCP-1
R5912	T8285	T8285	ROOT	was,was
R5913	T8286	T8287	advmod	significantly,higher
R5914	T8287	T8285	acomp	higher,was
R5915	T8288	T8285	prep	in,was
R5916	T8289	T8291	nmod	IAV,cells
R5917	T8290	T8291	amod	infected,cells
R5918	T8291	T8288	pobj	cells,in
R5919	T8292	T8291	acl	lacking,cells
R5920	T8293	T8292	dobj	A20,lacking
R5921	T8294	T8285	prep	compared,was
R5922	T8295	T8294	prep	to,compared
R5923	T8296	T8299	amod	infected,cells
R5924	T8297	T8299	amod	wild,cells
R5925	T8298	T8299	compound	type,cells
R5926	T8299	T8295	pobj	cells,to
R5927	T8300	T8301	punct	(,figure
R5928	T8301	T8299	parataxis	figure,cells
R5929	T8302	T8301	npadvmod	2C,figure
R5930	T8303	T8302	cc	and,2C
R5931	T8304	T8302	conj	figure,2C
R5932	T8305	T8304	nummod	S1,figure
R5933	T8306	T8301	punct	),figure
R5934	T8307	T8285	punct	.,was
R5935	T8308	T8312	prep	Taken,demonstrate
R5936	T8309	T8308	advmod	together,Taken
R5937	T8310	T8311	det	these,results
R5938	T8311	T8312	nsubj	results,demonstrate
R5939	T8312	T8312	ROOT	demonstrate,demonstrate
R5940	T8313	T8316	mark	that,regulates
R5941	T8314	T8316	nsubj	A20,regulates
R5942	T8315	T8316	advmod	negatively,regulates
R5943	T8316	T8312	ccomp	regulates,demonstrate
R5944	T8317	T8322	amod	IAV-induced,expression
R5945	T8318	T8322	amod	proinflammatory,expression
R5946	T8319	T8318	cc	and,proinflammatory
R5947	T8320	T8318	conj	antiviral,proinflammatory
R5948	T8321	T8322	compound	gene,expression
R5949	T8322	T8316	dobj	expression,regulates
R5950	T8323	T8322	prep	in,expression
R5951	T8324	T8325	amod	alveolar,macrophages
R5952	T8325	T8323	pobj	macrophages,in
R5953	T8326	T8322	punct	",",expression
R5954	T8327	T8322	amod	consistent,expression
R5955	T8328	T8327	prep	with,consistent
R5956	T8329	T8331	det	the,effect
R5957	T8330	T8331	amod	inhibitory,effect
R5958	T8331	T8328	pobj	effect,with
R5959	T8332	T8331	prep	of,effect
R5960	T8333	T8332	pobj	A20,of
R5961	T8334	T8331	acl	seen,effect
R5962	T8335	T8334	prep	on,seen
R5963	T8336	T8337	amod	RIG-I-induced,NF-κB
R5964	T8337	T8335	pobj	NF-κB,on
R5965	T8338	T8337	cc	and,NF-κB
R5966	T8339	T8340	amod	IRF3,activation
R5967	T8340	T8337	conj	activation,NF-κB
R5968	T8341	T8312	punct	.,demonstrate
R15304	T20475	T20477	nsubj	A20,regulates
R15305	T20476	T20477	advmod	negatively,regulates
R15306	T20477	T20477	ROOT	regulates,regulates
R15307	T20478	T20480	amod	IAV-induced,expression
R15308	T20479	T20480	compound	gene,expression
R15309	T20480	T20477	dobj	expression,regulates
R15310	T20481	T20480	prep	in,expression
R15311	T20482	T20481	pobj	BMDM,in
R15312	T20483	T20482	cc	and,BMDM
R15313	T20484	T20485	amod	alveolar,macrophages
R15314	T20485	T20482	conj	macrophages,BMDM
R15315	T20486	T20477	punct	.,regulates
R15316	T20487	T20492	punct	(,isolated
R15317	T20488	T20492	dobj	A,isolated
R15318	T20489	T20491	compound	B,BMDM
R15319	T20490	T20491	punct	),BMDM
R15320	T20491	T20492	nsubj	BMDM,isolated
R15321	T20492	T20492	ROOT	isolated,isolated
R15322	T20493	T20492	prep	from,isolated
R15323	T20494	T20497	amod	A20myel-WT,animals
R15324	T20495	T20494	cc	and,A20myel-WT
R15325	T20496	T20494	conj	A20myel-KO,A20myel-WT
R15326	T20497	T20493	pobj	animals,from
R15327	T20498	T20499	auxpass	were,infected
R15328	T20499	T20492	dep	infected,isolated
R15329	T20500	T20499	prep	with,infected
R15330	T20501	T20500	pobj	IAV,with
R15331	T20502	T20501	punct	(,IAV
R15332	T20503	T20501	nmod	moi,IAV
R15333	T20504	T20503	nummod	1,moi
R15334	T20505	T20504	punct	),1
R15335	T20506	T20492	punct	.,isolated
R15336	T20507	T20518	prep	At,lysed
R15337	T20508	T20509	amod	different,hours
R15338	T20509	T20510	compound	hours,post
R15339	T20510	T20511	compound	post,infection
R15340	T20511	T20507	pobj	infection,At
R15341	T20512	T20514	punct	(,p.i.
R15342	T20513	T20514	compound	hours,p.i.
R15343	T20514	T20511	appos	p.i.,infection
R15344	T20515	T20514	punct	),p.i.
R15345	T20516	T20518	nsubjpass	cells,lysed
R15346	T20517	T20518	auxpass	were,lysed
R15347	T20518	T20518	ROOT	lysed,lysed
R15348	T20519	T20518	cc	and,lysed
R15349	T20520	T20518	conj	IL-6,lysed
R15350	T20521	T20520	punct	",",IL-6
R15351	T20522	T20520	conj	IFNβ,IL-6
R15352	T20523	T20522	cc	and,IFNβ
R15353	T20524	T20525	compound	A20,mRNA
R15354	T20525	T20526	compound	mRNA,expression
R15355	T20526	T20522	conj	expression,IFNβ
R15356	T20527	T20528	auxpass	was,analyzed
R15357	T20528	T20518	conj	analyzed,lysed
R15358	T20529	T20528	agent	by,analyzed
R15359	T20530	T20529	pobj	qPCR,by
R15360	T20531	T20532	punct	(,A
R15361	T20532	T20530	appos	A,qPCR
R15362	T20533	T20530	punct	),qPCR
R15363	T20534	T20518	punct	.,lysed
R15364	T20535	T20536	nummod	18,hours
R15365	T20536	T20537	nsubj	hours,post
R15366	T20537	T20537	ROOT	post,post
R15367	T20538	T20540	compound	infection,culture
R15368	T20539	T20540	compound	cell,culture
R15369	T20540	T20537	dobj	culture,post
R15370	T20541	T20543	nsubjpass	supernatant,analyzed
R15371	T20542	T20543	auxpass	was,analyzed
R15372	T20543	T20537	relcl	analyzed,post
R15373	T20544	T20543	prep	for,analyzed
R15374	T20545	T20549	nmod	TNF,levels
R15375	T20546	T20545	cc	and,TNF
R15376	T20547	T20545	conj	IFNβ,TNF
R15377	T20548	T20549	compound	protein,levels
R15378	T20549	T20544	pobj	levels,for
R15379	T20550	T20543	agent	by,analyzed
R15380	T20551	T20550	pobj	ELISA,by
R15381	T20552	T20543	cc	and,analyzed
R15382	T20553	T20554	compound	multiplexing,technologies
R15383	T20554	T20537	advcl	technologies,post
R15384	T20555	T20556	punct	(,B
R15385	T20556	T20554	appos	B,technologies
R15386	T20557	T20554	punct	),technologies
R15387	T20558	T20537	punct	.,post
R15388	T20559	T20561	punct	(,D
R15389	T20560	T20561	meta	C,D
R15390	T20561	T20561	ROOT	D,D
R15391	T20562	T20561	punct	),D
R15392	T20563	T20564	compound	Alveolar,macrophages
R15393	T20564	T20565	nsubj	macrophages,were
R15394	T20565	T20567	auxpass	were,treated
R15395	T20566	T20567	amod	mock,treated
R15412	T20583	T20584	compound	mRNA,expression
R15413	T20584	T20580	conj	expression,IL-6
R15414	T20585	T20586	auxpass	was,determined
R15415	T20586	T20586	ROOT	determined,determined
R15416	T20587	T20586	agent	by,determined
R15417	T20588	T20587	pobj	qPCR,by
R15418	T20589	T20588	punct	(,qPCR
R15419	T20590	T20588	appos	C,qPCR
R15420	T20591	T20588	punct	),qPCR
R15421	T20592	T20586	punct	.,determined
R15422	T20593	T20594	compound	Cell,culture
R15423	T20594	T20595	compound	culture,supernatant
R15424	T20595	T20597	nsubjpass	supernatant,analyzed
R15425	T20596	T20597	auxpass	was,analyzed
R15426	T20597	T20597	ROOT	analyzed,analyzed
R15427	T20598	T20597	prep	for,analyzed
R15428	T20599	T20603	nmod	IL-6,levels
R15429	T20600	T20599	cc	and,IL-6
R15430	T20601	T20599	conj	IFNβ,IL-6
R15431	T20602	T20603	compound	protein,levels
R15432	T20603	T20598	pobj	levels,for
R15433	T20604	T20597	agent	by,analyzed
R15434	T20605	T20604	pobj	ELISA,by
R15435	T20606	T20597	cc	and,analyzed
R15436	T20607	T20608	compound	multiplexing,technologies
R15437	T20608	T20597	conj	technologies,analyzed
R15438	T20609	T20610	punct	(,D
R15439	T20610	T20608	appos	D,technologies
R15440	T20611	T20608	punct	),technologies
R15441	T20612	T20597	punct	.,analyzed
R15442	T20613	T20614	compound	Error,bars
R15443	T20614	T20615	nsubj	bars,represent
R15444	T20615	T20615	ROOT	represent,represent
R15445	T20616	T20617	amod	mean,values
R15446	T20617	T20615	dobj	values,represent
R15447	T20618	T20617	punct	(,values
R15448	T20619	T20622	advmod	+,SEM
R15449	T20620	T20622	compound	/,SEM
R15450	T20621	T20622	compound	−,SEM
R15451	T20622	T20617	appos	SEM,values
R15452	T20623	T20617	punct	),values
R15453	T20624	T20617	prep	of,values
R15454	T20625	T20624	pobj	2,of
R15455	T20626	T20627	nummod	3,samples
R15456	T20627	T20617	appos	samples,values
R15457	T20628	T20615	punct	.,represent
R15458	T20629	T20630	nsubj	Results,are
R15459	T20630	T20630	ROOT	are,are
R15460	T20631	T20630	acomp	representative,are
R15461	T20632	T20631	prep	for,representative
R15462	T20633	T20635	nummod	2,experiments
R15463	T20634	T20635	amod	independent,experiments
R15464	T20635	T20632	pobj	experiments,for
R15465	T20636	T20630	punct	.,are
R15466	T20637	T20639	dep	***,<
R15467	T20638	T20639	dep	p,<
R15468	T20639	T20640	intj	<,"0,001"
R15469	T20640	T20640	ROOT	"0,001","0,001"
R15470	T20641	T20640	punct	.,"0,001"
R5818	T8191	T8180	punct	.,contained
R5819	T8192	T8200	prep	Upon,are
R5820	T8193	T8194	compound	host,infection
R5821	T8194	T8192	pobj	infection,Upon
R5822	T8195	T8194	prep	with,infection
R5823	T8196	T8195	pobj	IAV,with
R5824	T8197	T8200	punct	",",are
R5825	T8198	T8199	amod	alveolar,macrophages
R5826	T8199	T8200	nsubj	macrophages,are
R15396	T20567	T20567	ROOT	treated,treated
R15397	T20568	T20567	cc	or,treated
R15398	T20569	T20567	conj	infected,treated
R15399	T20570	T20569	prep	with,infected
R15400	T20571	T20570	pobj	IAV,with
R15401	T20572	T20571	punct	(,IAV
R15402	T20573	T20574	nmod	moi,1
R15403	T20574	T20576	meta	1,for
R15404	T20575	T20574	punct	),1
R15405	T20576	T20569	prep	for,infected
R15406	T20577	T20578	nummod	18,hours
R15407	T20578	T20576	pobj	hours,for
R15408	T20579	T20567	punct	.,treated
R15409	T20580	T20586	nsubjpass	IL-6,determined
R15410	T20581	T20580	cc	and,IL-6
R15411	T20582	T20583	compound	IFNβ,mRNA

bionlp-st-ge-2016-test-tees

Id	Subject	Object	Predicate	Lexical cue
T20680	919-923	Protein	denotes	IFNβ
T20679	913-917	Protein	denotes	IL-6
T20678	667-670	Protein	denotes	A20
T20692	1309-1321	Protein	denotes	IFNβ protein
T20691	1300-1304	Protein	denotes	IL-6
T20690	1219-1229	Gene_expression	denotes	expression
T20689	1219-1229	Gene_expression	denotes	expression
T20688	1209-1218	Protein	denotes	IFNβ mRNA
T20687	1200-1204	Protein	denotes	IL-6
T20686	1048-1060	Protein	denotes	IFNβ protein
T20685	1040-1043	Protein	denotes	TNF
T20684	937-947	Gene_expression	denotes	expression
T20683	937-947	Gene_expression	denotes	expression
T20682	937-947	Gene_expression	denotes	expression
T20681	928-936	Protein	denotes	A20 mRNA
T8451	2402-2412	Positive_regulation	denotes	activation
T8450	2402-2412	Positive_regulation	denotes	activation
T8449	2397-2401	Protein	denotes	IRF3
T8448	2387-2392	Protein	denotes	NF-κB
T8447	2212-2215	Protein	denotes	A20
T8446	1909-1918	Localization	denotes	secretion
T8445	1909-1918	Localization	denotes	secretion
T8444	1909-1918	Localization	denotes	secretion
T8443	1894-1904	Gene_expression	denotes	Expression
T8442	1894-1904	Gene_expression	denotes	Expression
T8441	1894-1904	Gene_expression	denotes	Expression
T8440	1894-1904	Gene_expression	denotes	Expression
T8439	1894-1904	Gene_expression	denotes	Expression
T8438	1894-1904	Gene_expression	denotes	Expression
T8437	1894-1904	Gene_expression	denotes	Expression
T8436	1894-1904	Gene_expression	denotes	Expression
T8435	2036-2041	Protein	denotes	cxcl1
T8434	2032-2034	Protein	denotes	KC
T8433	2022-2026	Protein	denotes	ccl2
T8432	2004-2020	Protein	denotes	chemokines MCP-1
T8431	1990-1995	Protein	denotes	IFNα4
T8430	1970-1985	Protein	denotes	type-I IFN IFNβ
T8429	1961-1964	Protein	denotes	TNF
T8428	1942-1956	Protein	denotes	cytokines IL-6
T8427	605-609	Protein	denotes	IFNβ
T8426	597-600	Protein	denotes	TNF
T8425	386-394	Positive_regulation	denotes	enhanced
T8424	386-394	Positive_regulation	denotes	enhanced
T8423	395-405	Gene_expression	denotes	expression
T8422	395-405	Gene_expression	denotes	expression
T8421	418-422	Protein	denotes	IFNβ
T8420	409-413	Protein	denotes	IL-6
T8419	260-267	Positive_regulation	denotes	induced
T8418	231-239	Protein	denotes	A20 mRNA
T8417	88-91	Protein	denotes	A20
T8416	42-52	Gene_expression	denotes	expression
T8415	0-3	Protein	denotes	A20
R6014	T8415	T8416	themeOf	A20,expression
R6015	T8418	T8419	themeOf	A20 mRNA,induced
R6016	T8420	T8422	themeOf	IL-6,expression
R6017	T8421	T8423	themeOf	IFNβ,expression
R6018	T8422	T8424	themeOf	expression,enhanced
R6019	T8423	T8425	themeOf	expression,enhanced
R6020	T8428	T8436	themeOf	cytokines IL-6,Expression
R6021	T8429	T8437	themeOf	TNF,Expression
R6022	T8429	T8444	themeOf	TNF,secretion
R6023	T8430	T8438	themeOf	type-I IFN IFNβ,Expression
R6024	T8431	T8439	themeOf	IFNα4,Expression
R6025	T8432	T8440	themeOf	chemokines MCP-1,Expression
R6026	T8432	T8445	themeOf	chemokines MCP-1,secretion
R6027	T8433	T8441	themeOf	ccl2,Expression
R6028	T8434	T8442	themeOf	KC,Expression
R6029	T8434	T8446	themeOf	KC,secretion
R6030	T8435	T8443	themeOf	cxcl1,Expression
R6031	T8448	T8450	themeOf	NF-κB,activation
R6032	T8449	T8451	themeOf	IRF3,activation
R15479	T20679	T20682	themeOf	IL-6,expression
R15480	T20680	T20683	themeOf	IFNβ,expression
R15481	T20681	T20684	themeOf	A20 mRNA,expression
R15482	T20687	T20689	themeOf	IL-6,expression
R15483	T20688	T20690	themeOf	IFNβ mRNA,expression

testone

Id	Subject	Object	Predicate	Lexical cue
T20260	1214-1229	Transcription	denotes	mRNA expression
T20259	932-947	Transcription	denotes	mRNA expression
T20258	1309-1313	Protein	denotes	IFNβ
T20257	1300-1304	Protein	denotes	IL-6
T20256	1209-1213	Protein	denotes	IFNβ
T20255	1200-1204	Protein	denotes	IL-6
T20254	1048-1052	Protein	denotes	IFNβ
T20253	1040-1043	Protein	denotes	TNF
T20252	919-923	Protein	denotes	IFNβ
T20251	913-917	Protein	denotes	IL-6
T7659	2090-2097	Negative_regulation	denotes	lacking
T7658	1909-1918	Localization	denotes	secretion
T7657	1894-1904	Gene_expression	denotes	Expression
T7656	395-405	Gene_expression	denotes	expression
T7655	386-394	Positive_regulation	denotes	enhanced
T7654	302-311	Negative_regulation	denotes	deficient
T7653	260-267	Positive_regulation	denotes	induced
T7652	182-191	Negative_regulation	denotes	deficient
T7651	2397-2401	Protein	denotes	IRF3
T7650	2373-2378	Protein	denotes	RIG-I
T7649	2036-2041	Protein	denotes	cxcl1
T7648	2032-2034	Protein	denotes	KC
T7647	2022-2026	Protein	denotes	ccl2
T7646	2015-2020	Protein	denotes	MCP-1
T7645	1990-1995	Protein	denotes	IFNα4
T7644	1981-1985	Protein	denotes	IFNβ
T7643	1961-1964	Protein	denotes	TNF
T7642	1952-1956	Protein	denotes	IL-6
T7641	605-609	Protein	denotes	IFNβ
T7640	597-600	Protein	denotes	TNF
T7639	418-422	Protein	denotes	IFNβ
T7638	409-413	Protein	denotes	IL-6
R5381	T7638	T7656	themeOf	IL-6,expression
R5382	T7639	T7656	themeOf	IFNβ,expression
R5383	T7642	T7658	themeOf	IL-6,secretion
R5384	T7642	T7657	themeOf	IL-6,Expression
R5385	T7643	T7658	themeOf	TNF,secretion
R5386	T7644	T7658	themeOf	IFNβ,secretion
R5387	T7645	T7658	themeOf	IFNα4,secretion
R5388	T7646	T7658	themeOf	MCP-1,secretion
R5389	T7647	T7646	equivalentTo	ccl2,MCP-1
R5390	T7648	T7658	themeOf	KC,secretion
R5391	T7649	T7646	equivalentTo	cxcl1,MCP-1
R5392	T7649	T7648	equivalentTo	cxcl1,KC
R5393	T7656	T7655	themeOf	expression,enhanced
R15135	T20251	T20259	themeOf	IL-6,mRNA expression
R15136	T20252	T20259	themeOf	IFNβ,mRNA expression
R15137	T20255	T20260	themeOf	IL-6,mRNA expression
R15138	T20256	T20260	themeOf	IFNβ,mRNA expression

PMC:3291650 / 15209-17622 JSONTXT

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PMC:3291650 / 15209-17622 JSON TXT