PMC:3148254 / 9295-9432 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T4200	40-44	Protein	denotes	CD40
T4201	45-55	Positive_regulation	denotes	stimulated
T4202	56-68	Positive_regulation	denotes	upregulation
T4203	72-76	Protein	denotes	CD80
T4204	94-101	Negative_regulation	denotes	reduced
T4205	109-113	Protein	denotes	HOIP
T4206	114-123	Negative_regulation	denotes	deficient
R3225	T4200	T4201	causeOf	CD40,stimulated
R3226	T4202	T4201	themeOf	upregulation,stimulated
R3227	T4202	T4204	themeOf	upregulation,reduced
R3228	T4203	T4202	themeOf	CD80,upregulation
R3229	T4205	T4206	themeOf	HOIP,deficient
R3230	T4206	T4204	causeOf	deficient,reduced

Id	Subject	Object	Predicate	Lexical cue
T5278	40-44	Protein	denotes	CD40
T5279	72-76	Protein	denotes	CD80
T5280	56-68	Positive_regulation	denotes	upregulation
T5281	94-101	Negative_regulation	denotes	reduced
R4094	T5278	T5280	causeOf	CD40,upregulation
R4095	T5279	T5280	themeOf	CD80,upregulation
R4096	T5280	T5281	themeOf	upregulation,reduced

Id	Subject	Object	Predicate	Lexical cue
T5343	40-44	Protein	denotes	CD40
T5344	45-55	Positive_regulation	denotes	stimulated
T5345	56-68	Positive_regulation	denotes	upregulation
T5346	72-76	Protein	denotes	CD80
T5347	94-101	Negative_regulation	denotes	reduced
T5348	109-113	Protein	denotes	HOIP
T5349	114-123	Negative_regulation	denotes	deficient
R4127	T5343	T5344	causeOf	CD40,stimulated
R4128	T5345	T5344	themeOf	upregulation,stimulated
R4129	T5345	T5347	themeOf	upregulation,reduced
R4130	T5346	T5345	themeOf	CD80,upregulation
R4131	T5348	T5349	themeOf	HOIP,deficient
R4132	T5349	T5347	causeOf	deficient,reduced

Id	Subject	Object	Predicate	Lexical cue
T4718	0-8	VB	denotes	Compared
T4719	9-11	TO	denotes	to
T4720	12-15	DT	denotes	the
T4721	16-24	JJ	denotes	parental
T4722	25-29	NN	denotes	cell
T4723	30-34	NN	denotes	line
T4724	34-35	-COMMA-	denotes	,
T4725	36-39	DT	denotes	the
T4726	40-55	JJ	denotes	CD40-stimulated
T4727	56-68	NN	denotes	upregulation
T4728	69-71	IN	denotes	of
T4729	72-76	NN	denotes	CD80
T4730	77-80	VB	denotes	was
T4731	81-93	RB	denotes	dramatically
T4732	94-101	VB	denotes	reduced
T4733	102-104	IN	denotes	in
T4734	105-108	DT	denotes	all
T4735	109-123	JJ	denotes	HOIP-deficient
T4736	124-129	NN	denotes	cells
T4737	130-136	VB	denotes	tested
R3710	T4719	T4718	arg2Of	to,Compared
R3711	T4723	T4719	arg2Of	line,to
R3712	T4723	T4720	arg1Of	line,the
R3713	T4723	T4721	arg1Of	line,parental
R3714	T4723	T4722	arg1Of	line,cell
R3715	T4727	T4725	arg1Of	upregulation,the
R3716	T4727	T4726	arg1Of	upregulation,CD40-stimulated
R3717	T4727	T4728	arg1Of	upregulation,of
R3718	T4727	T4730	arg1Of	upregulation,was
R3719	T4727	T4732	arg2Of	upregulation,reduced
R3720	T4729	T4728	arg2Of	CD80,of
R3721	T4732	T4718	arg1Of	reduced,Compared
R3722	T4732	T4724	arg1Of	reduced,","
R3723	T4732	T4730	arg2Of	reduced,was
R3724	T4732	T4731	arg1Of	reduced,dramatically
R3725	T4732	T4733	arg1Of	reduced,in
R3726	T4736	T4733	arg2Of	cells,in
R3727	T4736	T4734	arg1Of	cells,all
R3728	T4736	T4735	arg1Of	cells,HOIP-deficient
R3729	T4736	T4737	arg2Of	cells,tested

Id	Subject	Object	Predicate	Lexical cue
T4342	0-8	VBN	denotes	Compared
T4343	9-11	TO	denotes	to
T4344	12-15	DT	denotes	the
T4345	16-24	JJ	denotes	parental
T4346	25-29	NN	denotes	cell
T4347	30-34	NN	denotes	line
T4348	34-35	,	denotes	,
T4349	36-39	DT	denotes	the
T4350	40-55	JJ	denotes	CD40-stimulated
T4351	56-68	NN	denotes	upregulation
T4352	69-71	IN	denotes	of
T4353	72-76	NN	denotes	CD80
T4354	77-80	VBD	denotes	was
T4355	81-93	RB	denotes	dramatically
T4356	94-101	VBN	denotes	reduced
T4357	102-104	IN	denotes	in
T4358	105-108	DT	denotes	all
T4359	109-123	JJ	denotes	HOIP-deficient
T4360	124-129	NNS	denotes	cells
T4361	130-136	VBN	denotes	tested
T4362	136-137	.	denotes	.
R3332	T4342	T4356	prep	Compared,reduced
R3333	T4343	T4342	prep	to,Compared
R3334	T4344	T4347	det	the,line
R3335	T4345	T4347	amod	parental,line
R3336	T4346	T4347	compound	cell,line
R3337	T4347	T4343	pobj	line,to
R3338	T4348	T4347	punct	",",line
R3339	T4349	T4351	det	the,upregulation
R3340	T4350	T4351	amod	CD40-stimulated,upregulation
R3341	T4351	T4356	nsubjpass	upregulation,reduced
R3342	T4352	T4351	prep	of,upregulation
R3343	T4353	T4352	pobj	CD80,of
R3344	T4354	T4356	auxpass	was,reduced
R3345	T4355	T4356	advmod	dramatically,reduced
R3346	T4356	T4356	ROOT	reduced,reduced
R3347	T4357	T4356	prep	in,reduced
R3348	T4358	T4360	det	all,cells
R3349	T4359	T4360	amod	HOIP-deficient,cells
R3350	T4360	T4357	pobj	cells,in
R3351	T4361	T4356	conj	tested,reduced
R3352	T4362	T4356	punct	.,reduced

Id	Subject	Object	Predicate	Lexical cue
T5101	124-129	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

Id	Subject	Object	Predicate	Lexical cue
T4248	0-137	Sentence	denotes	Compared to the parental cell line, the CD40-stimulated upregulation of CD80 was dramatically reduced in all HOIP-deficient cells tested.
T65	0-137	Sentence	denotes	Compared to the parental cell line, the CD40-stimulated upregulation of CD80 was dramatically reduced in all HOIP-deficient cells tested.

Id	Subject	Object	Predicate	Lexical cue
T5015	40-44	P25942	denotes	CD40
T5016	72-76	P33681	denotes	CD80
T5017	109-113	Q96EP0	denotes	HOIP

Id	Subject	Object	Predicate	Lexical cue	Speculation
T4128	40-44	Protein	denotes	CD40
T4129	45-55	Positive_regulation	denotes	stimulated
T4130	56-68	Positive_regulation	denotes	upregulation	true
T4131	72-76	Protein	denotes	CD80
T4132	94-101	Negative_regulation	denotes	reduced
T4133	109-113	Protein	denotes	HOIP
T4134	114-123	Negative_regulation	denotes	deficient
R3178	T4128	T4129	causeOf	CD40,stimulated
R3179	T4129	T4132	themeOf	stimulated,reduced
R3180	T4130	T4129	themeOf	upregulation,stimulated
R3181	T4130	T4132	themeOf	upregulation,reduced
R3182	T4131	T4130	themeOf	CD80,upregulation
R3183	T4133	T4134	themeOf	HOIP,deficient
R3184	T4134	T4132	causeOf	deficient,reduced