Several mutations which are reported to be lethal in animals have been found to be non-lethal in Arabidopsis. For example, homozygous mouse knockouts for ERCC1 died before weaning [20] while atercc1 plants were found to be phenotypically normal in absence of exogenous DNA damaging agents [21]. Same was true for RAD50, MRE11, RAD51, MUS81, BRCA1 and BARD1 also. CRY proteins, members of flavoproteins superfamily, are reported to be ubiquitous in all kingdoms of life. All members of this superfamily possess the characteristics of an N-terminal photolyase homology (PHR) domain. In bacteria, these enzymes mediate photoreactivation but the homologs of CRY protein, CRY1 and CRY2, in insects, animals and plants play a role in blue-light perception and circadian rhythm entrainment instead of DNA repair [22].