Table 1  Chlamydiaceae genome features with suspected host and niche specific genes
Species  Genome size (nt)  Protein coding sequences  Tryptophan metabolism  Toxin genes  Plasmid  Bacteriophage  tyrP copies  Nucleotide salvaging
C. pneumoniae AR39  1229853  1052   tph  Absent  Absent  Present  Two  guaBA-add, udk, pyrE
C. pneumoniae CWL029  1230230  1073   tph  Absent  Absent  Absent  Two  guaBA-add, udk, pyrE
C. pneumoniae J138  1226565  1072   tph  Absent  Absent  Absent  One  guaBA-add, udk, pyrE
C. pneumoniae TW183  1225935  1113   tph  Absent  Absent  Absent  One  guaBA-add, udk, pyrE
C. pneumoniae LPCoLN  1241024  1095   tph  Absent  Present  Present*  One   udk, pyrE
C. felis Fe/C-56  1166239  1005   trpABFCDR, kynU  Absent  Present  Absent  One  guaBA-add, pyrE
C. caviae GPIC  1173390  1009   trpABFCDR, kynU, prsA, tph  Present  Present  Present  One  guaBA-add, pyrE
C. abortus S26/3  1144377  961   tph  Absent  Absent  Present  One  guaB (pseudogene), pyrE
C. muridarum Nigg  1069412  924  none  Present  Present  Absent  Two  guaBA-add, upp
C. trachomatis serovar D  1042519  894   trpABCR  Present  Present  Absent  Two  None of the above
tph, tryptophan hydroxylase; trp, tryptophan biosynthesis; kynU, kynureninase; prsA, ribose-phosphate pyrophosphokinase; gua, purine biosynthesis; add, adenosine deaminase; udk, uridine kinase; pyrE, UMP synthase; upp, uracil phosphororibosyl transferase. * Asterisk indicates remnants.