PMC:3062687 / 5071-5319
Annnotations
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3832 | 23-27 | P23396 | denotes | RPS3 |
| T3833 | 28-32 | O14920 | denotes | IKKβ |
| T3834 | 61-65 | P23396 | denotes | RPS3 |
| T3835 | 113-117 | O14920 | denotes | IKKβ |
| T3836 | 202-206 | P23396 | denotes | RPS3 |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3551 | 0-2 | TO | denotes | To |
| T3552 | 3-10 | VB | denotes | examine |
| T3553 | 11-18 | IN | denotes | whether |
| T3554 | 19-22 | DT | denotes | the |
| T3555 | 23-32 | JJ | denotes | RPS3-IKKβ |
| T3556 | 33-44 | NN | denotes | interaction |
| T3557 | 45-47 | VB | denotes | is |
| T3558 | 48-56 | VB | denotes | required |
| T3559 | 57-60 | IN | denotes | for |
| T3560 | 61-65 | NN | denotes | RPS3 |
| T3561 | 66-73 | JJ | denotes | nuclear |
| T3562 | 74-87 | NN | denotes | translocation |
| T3563 | 87-88 | -COMMA- | denotes | , |
| T3564 | 89-91 | PRP | denotes | we |
| T3565 | 92-99 | VB | denotes | knocked |
| T3566 | 100-104 | RB | denotes | down |
| T3567 | 105-109 | NN | denotes | IKKα |
| T3568 | 110-112 | CC | denotes | or |
| T3569 | 113-117 | NN | denotes | IKKβ |
| T3570 | 118-128 | NN | denotes | expression |
| T3571 | 129-133 | IN | denotes | with |
| T3572 | 134-140 | NN | denotes | siRNAs |
| T3573 | 141-142 | -LRB- | denotes | ( |
| T3574 | 142-155 | NNP | denotes | Supplementary |
| T3575 | 156-160 | NNP | denotes | Fig. |
| T3576 | 161-162 | CD | denotes | 1 |
| T3577 | 162-163 | -RRB- | denotes | ) |
| T3578 | 164-167 | CC | denotes | and |
| T3579 | 168-172 | RB | denotes | then |
| T3580 | 173-181 | VB | denotes | observed |
| T3581 | 182-201 | JJ | denotes | stimulation-induced |
| T3582 | 202-206 | NN | denotes | RPS3 |
| T3583 | 207-214 | JJ | denotes | nuclear |
| T3584 | 215-224 | NN | denotes | migration |
| T3585 | 225-227 | IN | denotes | by |
| T3586 | 228-236 | JJ | denotes | confocal |
| T3587 | 237-247 | NN | denotes | microscopy |
| R2773 | T3552 | T3551 | arg1Of | examine,To |
| R2774 | T3556 | T3554 | arg1Of | interaction,the |
| R2775 | T3556 | T3555 | arg1Of | interaction,RPS3-IKKβ |
| R2776 | T3556 | T3557 | arg1Of | interaction,is |
| R2777 | T3556 | T3558 | arg2Of | interaction,required |
| R2778 | T3558 | T3552 | arg2Of | required,examine |
| R2779 | T3558 | T3553 | arg1Of | required,whether |
| R2780 | T3558 | T3557 | arg2Of | required,is |
| R2781 | T3558 | T3559 | arg1Of | required,for |
| R2782 | T3562 | T3559 | arg2Of | translocation,for |
| R2783 | T3562 | T3560 | arg1Of | translocation,RPS3 |
| R2784 | T3562 | T3561 | arg1Of | translocation,nuclear |
| R2785 | T3564 | T3552 | arg1Of | we,examine |
| R2786 | T3564 | T3565 | arg1Of | we,knocked |
| R2787 | T3565 | T3551 | modOf | knocked,To |
| R2788 | T3565 | T3563 | arg1Of | knocked,"," |
| R2789 | T3565 | T3566 | arg1Of | knocked,down |
| R2790 | T3567 | T3568 | arg1Of | IKKα,or |
| R2791 | T3568 | T3565 | arg2Of | or,knocked |
| R2792 | T3568 | T3571 | arg1Of | or,with |
| R2793 | T3570 | T3568 | arg2Of | expression,or |
| R2794 | T3570 | T3569 | arg1Of | expression,IKKβ |
| R2795 | T3572 | T3573 | arg1Of | siRNAs,( |
| R2796 | T3572 | T3578 | arg1Of | siRNAs,and |
| R2797 | T3575 | T3573 | arg2Of | Fig.,( |
| R2798 | T3575 | T3574 | arg1Of | Fig.,Supplementary |
| R2799 | T3575 | T3576 | arg1Of | Fig.,1 |
| R2800 | T3577 | T3573 | arg3Of | ),( |
| R2801 | T3578 | T3571 | arg2Of | and,with |
| R2802 | T3580 | T3579 | arg1Of | observed,then |
| R2803 | T3584 | T3578 | arg2Of | migration,and |
| R2804 | T3584 | T3580 | arg1Of | migration,observed |
| R2805 | T3584 | T3581 | arg1Of | migration,stimulation-induced |
| R2806 | T3584 | T3582 | arg1Of | migration,RPS3 |
| R2807 | T3584 | T3583 | arg1Of | migration,nuclear |
| R2808 | T3584 | T3585 | arg1Of | migration,by |
| R2809 | T3587 | T3585 | arg2Of | microscopy,by |
| R2810 | T3587 | T3586 | arg1Of | microscopy,confocal |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3866 | 0-2 | TO | denotes | To |
| T3867 | 3-10 | VB | denotes | examine |
| T3868 | 11-18 | IN | denotes | whether |
| T3869 | 19-22 | DT | denotes | the |
| T3870 | 23-32 | NN | denotes | RPS3-IKKβ |
| T3871 | 33-44 | NN | denotes | interaction |
| T3872 | 45-47 | VBZ | denotes | is |
| T3873 | 48-56 | VBN | denotes | required |
| T3874 | 57-60 | IN | denotes | for |
| T3875 | 61-65 | NNP | denotes | RPS3 |
| T3876 | 66-73 | JJ | denotes | nuclear |
| T3877 | 74-87 | NN | denotes | translocation |
| T3878 | 87-88 | , | denotes | , |
| T3879 | 89-91 | PRP | denotes | we |
| T3880 | 92-99 | VBD | denotes | knocked |
| T3881 | 100-104 | RP | denotes | down |
| T3882 | 105-109 | NNP | denotes | IKKα |
| T3883 | 110-112 | CC | denotes | or |
| T3884 | 113-117 | NNP | denotes | IKKβ |
| T3885 | 118-128 | NN | denotes | expression |
| T3886 | 129-133 | IN | denotes | with |
| T3887 | 134-140 | NNS | denotes | siRNAs |
| T3888 | 141-142 | -LRB- | denotes | ( |
| T3889 | 142-155 | NNP | denotes | Supplementary |
| T3890 | 156-160 | NNP | denotes | Fig. |
| T3891 | 161-162 | CD | denotes | 1 |
| T3892 | 162-163 | -RRB- | denotes | ) |
| T3893 | 164-167 | CC | denotes | and |
| T3894 | 168-172 | RB | denotes | then |
| T3895 | 173-181 | VBD | denotes | observed |
| T3896 | 182-201 | JJ | denotes | stimulation-induced |
| T3897 | 202-206 | NNP | denotes | RPS3 |
| T3898 | 207-214 | JJ | denotes | nuclear |
| T3899 | 215-224 | NN | denotes | migration |
| T3900 | 225-227 | IN | denotes | by |
| T3901 | 228-236 | JJ | denotes | confocal |
| T3902 | 237-247 | NN | denotes | microscopy |
| T3903 | 247-248 | . | denotes | . |
| R3057 | T3866 | T3867 | aux | To,examine |
| R3059 | T3868 | T3873 | mark | whether,required |
| R3060 | T3869 | T3871 | det | the,interaction |
| R3061 | T3870 | T3871 | compound | RPS3-IKKβ,interaction |
| R3062 | T3871 | T3873 | nsubjpass | interaction,required |
| R3063 | T3872 | T3873 | auxpass | is,required |
| R3064 | T3873 | T3867 | ccomp | required,examine |
| R3065 | T3874 | T3873 | prep | for,required |
| R3066 | T3875 | T3877 | nmod | RPS3,translocation |
| R3067 | T3876 | T3877 | amod | nuclear,translocation |
| R3068 | T3877 | T3874 | pobj | translocation,for |
| R3069 | T3878 | T3880 | punct | ",",knocked |
| R3070 | T3879 | T3880 | nsubj | we,knocked |
| R3071 | T3880 | T3880 | ROOT | knocked,knocked |
| R3072 | T3881 | T3880 | prt | down,knocked |
| R3073 | T3882 | T3885 | poss | IKKα,expression |
| R3074 | T3883 | T3882 | cc | or,IKKα |
| R3075 | T3884 | T3882 | conj | IKKβ,IKKα |
| R3076 | T3885 | T3880 | dobj | expression,knocked |
| R3077 | T3886 | T3880 | prep | with,knocked |
| R3078 | T3887 | T3886 | pobj | siRNAs,with |
| R3079 | T3888 | T3890 | punct | (,Fig. |
| R3080 | T3889 | T3890 | compound | Supplementary,Fig. |
| R3081 | T3890 | T3880 | parataxis | Fig.,knocked |
| R3082 | T3891 | T3890 | nummod | 1,Fig. |
| R3083 | T3892 | T3890 | punct | ),Fig. |
| R3084 | T3893 | T3880 | cc | and,knocked |
| R3085 | T3894 | T3895 | advmod | then,observed |
| R3086 | T3895 | T3880 | conj | observed,knocked |
| R3087 | T3896 | T3899 | amod | stimulation-induced,migration |
| R3088 | T3897 | T3899 | nmod | RPS3,migration |
| R3089 | T3898 | T3899 | amod | nuclear,migration |
| R3090 | T3899 | T3895 | dobj | migration,observed |
| R3091 | T3900 | T3899 | prep | by,migration |
| R3092 | T3901 | T3902 | amod | confocal,microscopy |
| R3093 | T3902 | T3900 | pobj | microscopy,by |
| R3094 | T3903 | T3880 | punct | .,knocked |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4265 | 207-224 | http://purl.obolibrary.org/obo/GO_0007097 | denotes | nuclear migration |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3533 | 0-248 | Sentence | denotes | To examine whether the RPS3-IKKβ interaction is required for RPS3 nuclear translocation, we knocked down IKKα or IKKβ expression with siRNAs (Supplementary Fig. 1) and then observed stimulation-induced RPS3 nuclear migration by confocal microscopy. |
| T39 | 0-248 | Sentence | denotes | To examine whether the RPS3-IKKβ interaction is required for RPS3 nuclear translocation, we knocked down IKKα or IKKβ expression with siRNAs (Supplementary Fig. 1) and then observed stimulation-induced RPS3 nuclear migration by confocal microscopy. |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T4615 | 23-27 | Protein | denotes | RPS3 | |
| T4616 | 28-32 | Protein | denotes | IKKβ | |
| T4617 | 33-44 | Binding | denotes | interaction | |
| T4618 | 48-56 | Positive_regulation | denotes | required | true |
| T4619 | 61-65 | Protein | denotes | RPS3 | |
| T4620 | 66-73 | Entity | denotes | nuclear | |
| T4621 | 74-87 | Localization | denotes | translocation | |
| T4622 | 92-104 | Negative_regulation | denotes | knocked down | |
| T4623 | 92-104 | Negative_regulation | denotes | knocked down | |
| T4624 | 105-109 | Protein | denotes | IKKα | |
| T4625 | 113-117 | Protein | denotes | IKKβ | |
| T4626 | 118-128 | Gene_expression | denotes | expression | |
| T4627 | 118-128 | Gene_expression | denotes | expression | |
| T4628 | 194-201 | Positive_regulation | denotes | induced | true |
| T4629 | 202-206 | Protein | denotes | RPS3 | |
| T4630 | 207-214 | Entity | denotes | nuclear | |
| T4631 | 215-224 | Localization | denotes | migration | |
| R3625 | T4615 | T4617 | themeOf | RPS3,interaction | |
| R3629 | T4616 | T4617 | themeOf | IKKβ,interaction | |
| R3632 | T4617 | T4618 | causeOf | interaction,required | |
| R3636 | T4619 | T4621 | themeOf | RPS3,translocation | |
| R3640 | T4620 | T4621 | locationOf | nuclear,translocation | |
| R3642 | T4621 | T4618 | themeOf | translocation,required | |
| R3647 | T4624 | T4626 | themeOf | IKKα,expression | |
| R3654 | T4625 | T4627 | themeOf | IKKβ,expression | |
| R3656 | T4626 | T4622 | themeOf | expression,knocked down | |
| R3658 | T4627 | T4623 | themeOf | expression,knocked down | |
| R3662 | T4629 | T4631 | themeOf | RPS3,migration | |
| R3667 | T4630 | T4631 | locationOf | nuclear,migration | |
| R3671 | T4631 | T4628 | themeOf | migration,induced |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4279 | 23-27 | Protein | denotes | RPS3 |
| T4280 | 28-32 | Protein | denotes | IKKβ |
| T4281 | 61-65 | Protein | denotes | RPS3 |
| T4282 | 105-109 | Protein | denotes | IKKα |
| T4283 | 113-117 | Protein | denotes | IKKβ |
| T4284 | 202-206 | Protein | denotes | RPS3 |
| T4285 | 33-44 | Binding | denotes | interaction |
| T4286 | 66-73 | Entity | denotes | nuclear |
| T4287 | 74-87 | Localization | denotes | translocation |
| T4288 | 118-128 | Gene_expression | denotes | expression |
| T4289 | 118-128 | Gene_expression | denotes | expression |
| T4290 | 207-214 | Entity | denotes | nuclear |
| T4291 | 215-224 | Localization | denotes | migration |
| T4292 | 48-56 | Positive_regulation | denotes | required |
| T4293 | 182-201 | Positive_regulation | denotes | stimulation-induced |
| R3432 | T4279 | T4285 | themeOf | RPS3,interaction |
| R3433 | T4280 | T4285 | themeOf | IKKβ,interaction |
| R3434 | T4281 | T4287 | themeOf | RPS3,translocation |
| R3435 | T4282 | T4288 | themeOf | IKKα,expression |
| R3436 | T4283 | T4289 | themeOf | IKKβ,expression |
| R3437 | T4284 | T4291 | themeOf | RPS3,migration |
| R3438 | T4285 | T4292 | causeOf | interaction,required |
| R3439 | T4286 | T4287 | locationOf | nuclear,translocation |
| R3440 | T4287 | T4292 | themeOf | translocation,required |
| R3441 | T4290 | T4291 | locationOf | nuclear,migration |
| R3442 | T4291 | T4293 | themeOf | migration,stimulation-induced |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T3443 | 23-27 | Protein | denotes | RPS3 | |
| T3444 | 28-32 | Protein | denotes | IKKβ | |
| T3445 | 33-44 | Binding | denotes | interaction | |
| T3446 | 48-56 | Positive_regulation | denotes | required | true |
| T3447 | 61-65 | Protein | denotes | RPS3 | |
| T3448 | 66-73 | Entity | denotes | nuclear | |
| T3449 | 74-87 | Localization | denotes | translocation | |
| T3450 | 92-104 | Negative_regulation | denotes | knocked down | |
| T3451 | 92-104 | Negative_regulation | denotes | knocked down | |
| T3452 | 105-109 | Protein | denotes | IKKα | |
| T3453 | 113-117 | Protein | denotes | IKKβ | |
| T3454 | 118-128 | Gene_expression | denotes | expression | |
| T3455 | 118-128 | Gene_expression | denotes | expression | |
| T3456 | 194-201 | Positive_regulation | denotes | induced | true |
| T3457 | 202-206 | Protein | denotes | RPS3 | |
| T3458 | 207-214 | Entity | denotes | nuclear | |
| T3459 | 215-224 | Localization | denotes | migration | |
| R2692 | T3443 | T3445 | themeOf | RPS3,interaction | |
| R2693 | T3444 | T3445 | themeOf | IKKβ,interaction | |
| R2694 | T3445 | T3446 | causeOf | interaction,required | |
| R2695 | T3447 | T3449 | themeOf | RPS3,translocation | |
| R2696 | T3448 | T3449 | locationOf | nuclear,translocation | |
| R2697 | T3449 | T3446 | themeOf | translocation,required | |
| R2698 | T3452 | T3454 | themeOf | IKKα,expression | |
| R2699 | T3453 | T3455 | themeOf | IKKβ,expression | |
| R2700 | T3454 | T3450 | themeOf | expression,knocked down | |
| R2701 | T3455 | T3451 | themeOf | expression,knocked down | |
| R2702 | T3457 | T3459 | themeOf | RPS3,migration | |
| R2703 | T3458 | T3459 | locationOf | nuclear,migration | |
| R2704 | T3459 | T3456 | themeOf | migration,induced |
test2
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T3359 | 23-27 | Protein | denotes | RPS3 | |
| T3360 | 28-32 | Protein | denotes | IKKβ | |
| T3361 | 33-44 | Binding | denotes | interaction | |
| T3362 | 48-56 | Positive_regulation | denotes | required | |
| T3363 | 61-65 | Protein | denotes | RPS3 | true |
| T3364 | 66-73 | Entity | denotes | nuclear | |
| T3365 | 74-87 | Localization | denotes | translocation | |
| T3366 | 92-104 | Negative_regulation | denotes | knocked down | |
| T3367 | 105-109 | Protein | denotes | IKKα | |
| T3368 | 113-117 | Protein | denotes | IKKβ | |
| T3369 | 118-128 | Gene_expression | denotes | expression | |
| T3370 | 194-201 | Positive_regulation | denotes | induced | |
| T3371 | 202-206 | Protein | denotes | RPS3 | |
| T3372 | 207-214 | Entity | denotes | nuclear | |
| T3373 | 215-224 | Localization | denotes | migration | |
| R2629 | T3359 | T3361 | themeOf | RPS3,interaction | |
| R2630 | T3360 | T3361 | themeOf | IKKβ,interaction | |
| R2631 | T3361 | T3362 | causeOf | interaction,required | |
| R2632 | T3363 | T3365 | themeOf | RPS3,translocation | |
| R2633 | T3364 | T3365 | locationOf | nuclear,translocation | |
| R2634 | T3365 | T3362 | themeOf | translocation,required | |
| R2635 | T3367 | T3369 | themeOf | IKKα,expression | |
| R2636 | T3368 | T3369 | themeOf | IKKβ,expression | |
| R2637 | T3369 | T3366 | themeOf | expression,knocked down | |
| R2638 | T3371 | T3373 | themeOf | RPS3,migration | |
| R2639 | T3372 | T3373 | locationOf | nuclear,migration | |
| R2640 | T3373 | T3370 | themeOf | migration,induced |