PMC:3062687 / 483-760 JSONTXT

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T245","span":{"begin":76,"end":81},"obj":"P23396"},{"id":"T246","span":{"begin":105,"end":109},"obj":"P23396"},{"id":"T247","span":{"begin":143,"end":147},"obj":"P23396"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"pmc-enju-pas","denotations":[{"id":"T173","span":{"begin":0,"end":8},"obj":"RB"},{"id":"T174","span":{"begin":8,"end":9},"obj":"-COMMA-"},{"id":"T175","span":{"begin":10,"end":13},"obj":"DT"},{"id":"T176","span":{"begin":14,"end":23},"obj":"JJ"},{"id":"T177","span":{"begin":24,"end":32},"obj":"NN"},{"id":"T178","span":{"begin":33,"end":44},"obj":"FW"},{"id":"T179","span":{"begin":45,"end":49},"obj":"FW"},{"id":"T180","span":{"begin":50,"end":54},"obj":"NN"},{"id":"T181","span":{"begin":54,"end":55},"obj":"-COLON-"},{"id":"T182","span":{"begin":55,"end":57},"obj":"NN"},{"id":"T183","span":{"begin":58,"end":67},"obj":"NN"},{"id":"T184","span":{"begin":68,"end":75},"obj":"NN"},{"id":"T185","span":{"begin":76,"end":81},"obj":"NN"},{"id":"T186","span":{"begin":82,"end":94},"obj":"RB"},{"id":"T187","span":{"begin":95,"end":104},"obj":"VB"},{"id":"T188","span":{"begin":105,"end":109},"obj":"NN"},{"id":"T189","span":{"begin":110,"end":114},"obj":"NN"},{"id":"T190","span":{"begin":115,"end":130},"obj":"NN"},{"id":"T191","span":{"begin":131,"end":134},"obj":"CC"},{"id":"T192","span":{"begin":135,"end":142},"obj":"VB"},{"id":"T193","span":{"begin":143,"end":147},"obj":"NN"},{"id":"T194","span":{"begin":148,"end":156},"obj":"NN"},{"id":"T195","span":{"begin":156,"end":157},"obj":"-COMMA-"},{"id":"T196","span":{"begin":158,"end":165},"obj":"RB"},{"id":"T197","span":{"begin":166,"end":175},"obj":"VB"},{"id":"T198","span":{"begin":176,"end":185},"obj":"JJ"},{"id":"T199","span":{"begin":186,"end":198},"obj":"NN"},{"id":"T200","span":{"begin":199,"end":202},"obj":"CC"},{"id":"T201","span":{"begin":203,"end":211},"obj":"NN"},{"id":"T202","span":{"begin":212,"end":215},"obj":"CC"},{"id":"T203","span":{"begin":216,"end":226},"obj":"VB"},{"id":"T204","span":{"begin":227,"end":236},"obj":"NN"},{"id":"T205","span":{"begin":237,"end":239},"obj":"IN"},{"id":"T206","span":{"begin":240,"end":241},"obj":"DT"},{"id":"T207","span":{"begin":242,"end":253},"obj":"JJ"},{"id":"T208","span":{"begin":254,"end":260},"obj":"NN"},{"id":"T209","span":{"begin":261,"end":270},"obj":"NN"},{"id":"T210","span":{"begin":271,"end":276},"obj":"NN"}],"relations":[{"id":"R150","pred":"arg1Of","subj":"T180","obj":"T176"},{"id":"R151","pred":"arg1Of","subj":"T180","obj":"T177"},{"id":"R152","pred":"arg1Of","subj":"T180","obj":"T178"},{"id":"R153","pred":"arg1Of","subj":"T180","obj":"T179"},{"id":"R154","pred":"arg1Of","subj":"T180","obj":"T181"},{"id":"R155","pred":"arg1Of","subj":"T181","obj":"T175"},{"id":"R156","pred":"arg1Of","subj":"T181","obj":"T187"},{"id":"R157","pred":"arg1Of","subj":"T181","obj":"T192"},{"id":"R158","pred":"arg1Of","subj":"T181","obj":"T197"},{"id":"R159","pred":"arg1Of","subj":"T181","obj":"T203"},{"id":"R160","pred":"arg2Of","subj":"T185","obj":"T181"},{"id":"R161","pred":"arg1Of","subj":"T185","obj":"T182"},{"id":"R162","pred":"arg1Of","subj":"T185","obj":"T183"},{"id":"R163","pred":"arg1Of","subj":"T185","obj":"T184"},{"id":"R164","pred":"arg1Of","subj":"T187","obj":"T191"},{"id":"R165","pred":"arg2Of","subj":"T190","obj":"T187"},{"id":"R166","pred":"arg1Of","subj":"T190","obj":"T188"},{"id":"R167","pred":"arg1Of","subj":"T190","obj":"T189"},{"id":"R168","pred":"arg1Of","subj":"T191","obj":"T173"},{"id":"R169","pred":"arg1Of","subj":"T191","obj":"T174"},{"id":"R170","pred":"arg1Of","subj":"T191","obj":"T186"},{"id":"R171","pred":"arg1Of","subj":"T191","obj":"T195"},{"id":"R172","pred":"modOf","subj":"T191","obj":"T197"},{"id":"R173","pred":"modOf","subj":"T191","obj":"T203"},{"id":"R174","pred":"arg2Of","subj":"T192","obj":"T191"},{"id":"R175","pred":"arg2Of","subj":"T194","obj":"T192"},{"id":"R176","pred":"arg1Of","subj":"T194","obj":"T193"},{"id":"R177","pred":"arg1Of","subj":"T197","obj":"T202"},{"id":"R178","pred":"arg1Of","subj":"T199","obj":"T200"},{"id":"R179","pred":"arg2Of","subj":"T200","obj":"T197"},{"id":"R180","pred":"arg1Of","subj":"T200","obj":"T198"},{"id":"R181","pred":"arg2Of","subj":"T201","obj":"T200"},{"id":"R182","pred":"arg1Of","subj":"T202","obj":"T196"},{"id":"R183","pred":"arg2Of","subj":"T203","obj":"T202"},{"id":"R184","pred":"arg1Of","subj":"T203","obj":"T205"},{"id":"R185","pred":"arg2Of","subj":"T204","obj":"T203"},{"id":"R186","pred":"arg2Of","subj":"T210","obj":"T205"},{"id":"R187","pred":"arg1Of","subj":"T210","obj":"T206"},{"id":"R188","pred":"arg1Of","subj":"T210","obj":"T207"},{"id":"R189","pred":"arg1Of","subj":"T210","obj":"T208"},{"id":"R190","pred":"arg1Of","subj":"T210","obj":"T209"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T326","span":{"begin":0,"end":8},"obj":"RB"},{"id":"T327","span":{"begin":8,"end":9},"obj":","},{"id":"T328","span":{"begin":10,"end":13},"obj":"DT"},{"id":"T329","span":{"begin":14,"end":23},"obj":"NN"},{"id":"T330","span":{"begin":24,"end":32},"obj":"NN"},{"id":"T331","span":{"begin":33,"end":44},"obj":"NNP"},{"id":"T332","span":{"begin":45,"end":49},"obj":"NNS"},{"id":"T333","span":{"begin":50,"end":54},"obj":"NNP"},{"id":"T334","span":{"begin":54,"end":55},"obj":":"},{"id":"T335","span":{"begin":55,"end":57},"obj":"NNP"},{"id":"T336","span":{"begin":58,"end":67},"obj":"NN"},{"id":"T337","span":{"begin":68,"end":75},"obj":"NN"},{"id":"T338","span":{"begin":76,"end":81},"obj":"NNP"},{"id":"T339","span":{"begin":82,"end":94},"obj":"RB"},{"id":"T340","span":{"begin":95,"end":104},"obj":"VBD"},{"id":"T341","span":{"begin":105,"end":109},"obj":"NNP"},{"id":"T342","span":{"begin":110,"end":114},"obj":"NNP"},{"id":"T343","span":{"begin":115,"end":130},"obj":"NN"},{"id":"T344","span":{"begin":131,"end":134},"obj":"CC"},{"id":"T345","span":{"begin":135,"end":142},"obj":"VBD"},{"id":"T346","span":{"begin":143,"end":147},"obj":"CD"},{"id":"T347","span":{"begin":148,"end":156},"obj":"NN"},{"id":"T348","span":{"begin":156,"end":157},"obj":","},{"id":"T349","span":{"begin":158,"end":165},"obj":"RB"},{"id":"T350","span":{"begin":166,"end":175},"obj":"VBG"},{"id":"T351","span":{"begin":176,"end":185},"obj":"JJ"},{"id":"T352","span":{"begin":186,"end":198},"obj":"NN"},{"id":"T353","span":{"begin":199,"end":202},"obj":"CC"},{"id":"T354","span":{"begin":203,"end":211},"obj":"NN"},{"id":"T355","span":{"begin":212,"end":215},"obj":"CC"},{"id":"T356","span":{"begin":216,"end":226},"obj":"VBG"},{"id":"T357","span":{"begin":227,"end":236},"obj":"NN"},{"id":"T358","span":{"begin":237,"end":239},"obj":"IN"},{"id":"T359","span":{"begin":240,"end":241},"obj":"DT"},{"id":"T360","span":{"begin":242,"end":253},"obj":"JJ"},{"id":"T361","span":{"begin":254,"end":260},"obj":"NN"},{"id":"T362","span":{"begin":261,"end":270},"obj":"NN"},{"id":"T363","span":{"begin":271,"end":276},"obj":"NN"},{"id":"T364","span":{"begin":276,"end":277},"obj":"."}],"relations":[{"id":"R260","pred":"advmod","subj":"T326","obj":"T340"},{"id":"R261","pred":"punct","subj":"T327","obj":"T340"},{"id":"R262","pred":"det","subj":"T328","obj":"T330"},{"id":"R263","pred":"compound","subj":"T329","obj":"T330"},{"id":"R264","pred":"nsubj","subj":"T330","obj":"T340"},{"id":"R265","pred":"compound","subj":"T331","obj":"T332"},{"id":"R266","pred":"compound","subj":"T332","obj":"T333"},{"id":"R267","pred":"appos","subj":"T333","obj":"T330"},{"id":"R268","pred":"punct","subj":"T334","obj":"T333"},{"id":"R269","pred":"compound","subj":"T335","obj":"T337"},{"id":"R270","pred":"compound","subj":"T336","obj":"T337"},{"id":"R271","pred":"conj","subj":"T337","obj":"T330"},{"id":"R272","pred":"nsubj","subj":"T338","obj":"T340"},{"id":"R273","pred":"advmod","subj":"T339","obj":"T340"},{"id":"R274","pred":"ROOT","subj":"T340","obj":"T340"},{"id":"R275","pred":"compound","subj":"T341","obj":"T343"},{"id":"R276","pred":"compound","subj":"T342","obj":"T343"},{"id":"R277","pred":"dobj","subj":"T343","obj":"T340"},{"id":"R278","pred":"cc","subj":"T344","obj":"T340"},{"id":"R279","pred":"conj","subj":"T345","obj":"T340"},{"id":"R280","pred":"nummod","subj":"T346","obj":"T347"},{"id":"R281","pred":"dobj","subj":"T347","obj":"T345"},{"id":"R282","pred":"punct","subj":"T348","obj":"T345"},{"id":"R283","pred":"advmod","subj":"T349","obj":"T350"},{"id":"R284","pred":"advcl","subj":"T350","obj":"T345"},{"id":"R285","pred":"amod","subj":"T351","obj":"T352"},{"id":"R286","pred":"dobj","subj":"T352","obj":"T350"},{"id":"R287","pred":"cc","subj":"T353","obj":"T352"},{"id":"R288","pred":"conj","subj":"T354","obj":"T352"},{"id":"R289","pred":"cc","subj":"T355","obj":"T350"},{"id":"R290","pred":"conj","subj":"T356","obj":"T350"},{"id":"R291","pred":"dobj","subj":"T357","obj":"T356"},{"id":"R292","pred":"prep","subj":"T358","obj":"T356"},{"id":"R293","pred":"det","subj":"T359","obj":"T363"},{"id":"R294","pred":"amod","subj":"T360","obj":"T363"},{"id":"R295","pred":"compound","subj":"T361","obj":"T363"},{"id":"R296","pred":"compound","subj":"T362","obj":"T363"},{"id":"R297","pred":"pobj","subj":"T363","obj":"T358"},{"id":"R298","pred":"punct","subj":"T364","obj":"T340"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"GO-BP","denotations":[{"id":"T434","span":{"begin":115,"end":130},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T438","span":{"begin":58,"end":67},"obj":"http://purl.obolibrary.org/obo/GO_0009405"},{"id":"T439","span":{"begin":58,"end":67},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"sentences","denotations":[{"id":"T98","span":{"begin":0,"end":277},"obj":"Sentence"},{"id":"T6","span":{"begin":0,"end":277},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"events-check-again","denotations":[{"id":"T583","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T584","span":{"begin":95,"end":104},"obj":"Negative_regulation"},{"id":"T585","span":{"begin":105,"end":109},"obj":"Protein"},{"id":"T586","span":{"begin":110,"end":114},"obj":"Entity"},{"id":"T587","span":{"begin":115,"end":130},"obj":"Phosphorylation"},{"id":"T588","span":{"begin":135,"end":142},"obj":"Negative_regulation"},{"id":"T589","span":{"begin":143,"end":147},"obj":"Protein"}],"relations":[{"id":"R457","pred":"causeOf","subj":"T583","obj":"T584"},{"id":"R458","pred":"causeOf","subj":"T584","obj":"T588"},{"id":"R459","pred":"themeOf","subj":"T586","obj":"T587"},{"id":"R460","pred":"partOf","subj":"T586","obj":"T585"},{"id":"R461","pred":"themeOf","subj":"T587","obj":"T584"},{"id":"R462","pred":"themeOf","subj":"T589","obj":"T588"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T520","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T521","span":{"begin":105,"end":114},"obj":"Protein"},{"id":"T522","span":{"begin":143,"end":147},"obj":"Protein"},{"id":"T523","span":{"begin":115,"end":130},"obj":"Phosphorylation"},{"id":"T524","span":{"begin":135,"end":142},"obj":"Negative_regulation"},{"id":"T525","span":{"begin":95,"end":104},"obj":"Negative_regulation"}],"relations":[{"id":"R408","pred":"themeOf","subj":"T521","obj":"T523"},{"id":"R409","pred":"themeOf","subj":"T522","obj":"T524"},{"id":"R410","pred":"themeOf","subj":"T523","obj":"T525"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T83","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T84","span":{"begin":95,"end":104},"obj":"Negative_regulation"},{"id":"T85","span":{"begin":105,"end":109},"obj":"Protein"},{"id":"T86","span":{"begin":110,"end":114},"obj":"Entity"},{"id":"T87","span":{"begin":115,"end":130},"obj":"Phosphorylation"},{"id":"T88","span":{"begin":135,"end":142},"obj":"Negative_regulation"},{"id":"T89","span":{"begin":143,"end":147},"obj":"Protein"}],"relations":[{"id":"R69","pred":"causeOf","subj":"T83","obj":"T84"},{"id":"R70","pred":"causeOf","subj":"T84","obj":"T88"},{"id":"R71","pred":"themeOf","subj":"T86","obj":"T87"},{"id":"R72","pred":"partOf","subj":"T86","obj":"T85"},{"id":"R73","pred":"themeOf","subj":"T87","obj":"T84"},{"id":"R74","pred":"themeOf","subj":"T89","obj":"T88"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}

{"project":"test2","denotations":[{"id":"T53","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T54","span":{"begin":95,"end":104},"obj":"Negative_regulation"},{"id":"T55","span":{"begin":105,"end":109},"obj":"Protein"},{"id":"T56","span":{"begin":110,"end":114},"obj":"Entity"},{"id":"T57","span":{"begin":115,"end":130},"obj":"Phosphorylation"},{"id":"T58","span":{"begin":135,"end":142},"obj":"Negative_regulation"},{"id":"T59","span":{"begin":143,"end":147},"obj":"Protein"}],"relations":[{"id":"R45","pred":"causeOf","subj":"T53","obj":"T54"},{"id":"R46","pred":"causeOf","subj":"T54","obj":"T58"},{"id":"R47","pred":"partOf","subj":"T56","obj":"T55"},{"id":"R48","pred":"themeOf","subj":"T56","obj":"T57"},{"id":"R49","pred":"themeOf","subj":"T57","obj":"T54"},{"id":"R50","pred":"themeOf","subj":"T59","obj":"T58"}],"text":"Moreover, the foodborne pathogen Escherichia coli O157:H7 virulence protein NleH1 specifically inhibited RPS3 S209 phosphorylation and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea but decreasing mortality in a gnotobiotic piglet infection model."}