Bcl-2 Family Caspase Family IAP Family Tumor Suppressor Anti-apoptotic proteins Pro-apoptotic proteins Bcl-2 Bax Apoptosis “initiators”: caspase-2, 8, 9, 10 NAIP p53 Bcl-xL Bak1 Apollon p63 Mcl-1 Bcl-xS Survivin p73 Boo/Diva Bad Apoptosis “executioners”: caspase-2, 3, 6, 7 IAP1     Bid IAP2     Bik XIAP     Bim Cytokine processors: caspase-1, 4, 5, 11, 12, 14       Noxa       Puma