Odds ratios were adjusted for gestational age and concentration of sample at visit 1, smoking, maternal age, race or ethnic group, body mass index, and treatment group. Odds ratios for sFlt1, sEng and sFlt1+Endo/PIGF represent the odds of developing preeclampsia compared to control subjects for each 1-unit increase of the factor, and the odds ratio for PlGF represents a 10-unit increase of the factor among preeclamptic subjects compared to controls.