PMC:2948165 / 8198-9697 JSONTXT

{"project":"TEST0","denotations":[{"id":"20585784-131-137-46858","span":{"begin":131,"end":133},"obj":"[\"10548768\"]"},{"id":"20585784-197-202-46859","span":{"begin":538,"end":539},"obj":"[\"9530296\"]"},{"id":"20585784-105-110-46860","span":{"begin":1475,"end":1476},"obj":"[\"9862835\"]"}],"text":"As part of the post-processing, in most studies, the outline of the stomach is drawn manually and special software (such as MASS© [21]) is used. Slices encompassing the entire stomach are then summed up to measure momentary gastric volume. As a function in time, the percentage in decrease of the gastric volume represents gastric emptying. As gastric secretions mix with the meal and thereby influence gastric volume, Kunz et al. designed a robust method to correct gastric meal volume for progressive dilution due to gastric secretion [4]. First, the relationship between dilution of gastric content by gastric secretions and signal intensity for meals was experimentally determined by filling small bottles with defined quantities of the meal and mixing them with increasing quantities of hydrochloric acid. Then, the bottles were imaged simultaneously in a single plane. With liquid meals, an exponential correlation was found between the concentration of hydrochloric acid and the signal intensity. During gastric emptying studies, an external standard (containing the same meal that the subject had just ingested consisting of a mixture of fluid or solid food mixed with contrast medium) was placed in a polyethylene tube beside the subject and imaged simultaneously. The image intensity of the tube content served as a reference to correct for gastric secretion. An increase in gastric secretion resulted in a decrease in the signal intensity of the gastric contents [8]. (2) Gastric motility"}

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