Both MVO and IMH occur exclusively in myocardium that sustains the most severe ischaemia and are therefore confined to the central portions of infarcted myocardium [3]. As IMH is caused by extravasation of blood into the extravascular space as a consequence of ischaemic microvascular damage, it only occurs in reperfused AMI [4, 5]. IMH does not depend on the magnitude of early reflow but, similar to MVO, on the severity of ischaemia as reflected by a longer duration of coronary occlusion and low collateral flow [6, 7].