Reader #a True positives True negatives False positives False negatives M M+A M M+A M M+A M M+A 1 28 45 32 21 27 30 15 6 2 28 45 25 21 33 30 16 6 3 25 44 30 20 32 31 15 7 4 26 43 20 28 43 23 13 8 5 26 43 32 30 28 21 16 8 6 32 43 20 37 43 14 7 8 7 26 41 25 27 33 24 18 10 8 23 40 35 31 17 20 27 11 9 16 40 43 25 21 26 22 11 10 27 39 34 36 27 15 14 12 11 26 37 35 41 24 10 17 14 12 22 37 37 34 20 17 23 14 Mean # of cases 25.4 41.4 30.7 29.3 29.0 21.8 16.9 9.6 % of 51 cases 49.8% 81.2% 60.2% 57.5% 56.9% 42.7% 33.1% 18.8% Mean # of added cases 16.0 −1.4 −7.2 −7.3 Mean % of 51 cases added 31.4% −2.7% −14.1% −14.3% % improvement compared with M alone 63% −4% −25% −43%