Motor impairment after stroke is the major cause of permanent disability. Recovery of hand motor function is crucial in order to perform activities of daily living, but is often variable and incomplete (Duncan et al., 1992). Indeed, stroke rehabilitation efficacy is limited (de Pedro-Cuesta et al., 1992; Duncan, 1997) with 30 to 60% of patients unable to use their more affected arms functionally after discharge (Kwakkel et al., 1999; Lai et al., 2002). Currently, neuroscience-based rehabilitation seeks to stimulate spontaneous functional motor recovery by capitalizing on the inherent potential of the brain for plastic reorganization after stroke (Chollet et al., 1991; Netz et al., 1997; Platz et al., 2000; Feydy et al., 2002; Cramer, 2004; Dobkin, 2004; Ward and Cohen, 2004; Gerloff et al., 2006; Nudo, 2006).