Even in myoclonus as in movement disorders (Hanna and Bhatia, 1997; Waldbaum and Patel, 2010), mitochondrial dysfunction seems to be part of the pathophysiological basis and might be the target of piracetam's therapeutical benefit (Ikeda et al., 1996; Karacostas et al., 1999; Wolters and Benecke, 2009).