PMC:2944646 / 14040-14991 JSONTXT

{"project":"TEST0","denotations":[{"id":"20877425-41-49-198929","span":{"begin":351,"end":355},"obj":"[\"16520237\"]"}],"text":"Figure 1 Piracetam reduces measures of mitochondrial dysfunction in NMRI mice – higher sensitivity in aged mice 2–3 months old and 22–24 months old NMRI mice were treated for 14 days with 0.5 g piracetam/kg in 0.9% NaCI solution p.o. once daily for 2 weeks. Control animals received 0.9% NaCI solution alone. All data are modified after Keil et al. (2006). (A) Dissociated brain cells were isolated and MMP was detected. The MMP was significantly reduced in old animals (22 months) and protected by Piracetam. Data are expressed as mean ± SEM (n = 6–8) *p \u003c 0.05 piracetam treated old animals vs. aged controls. (B,C) Effects of aging and treatment with piracetam on SOD, and GPx in young and old animals. Activities of antioxidant enzymes are increased in aged mice. Treatment with piracetam reduces the enzyme activities significantly in old mice. Data are expressed as mean ± SEM (n = 7). *p \u003c 0.05 piracetam treated old animals vs. aged controls."}

{"project":"0_colil","denotations":[{"id":"20877425-16520237-198929","span":{"begin":351,"end":355},"obj":"16520237"}],"text":"Figure 1 Piracetam reduces measures of mitochondrial dysfunction in NMRI mice – higher sensitivity in aged mice 2–3 months old and 22–24 months old NMRI mice were treated for 14 days with 0.5 g piracetam/kg in 0.9% NaCI solution p.o. once daily for 2 weeks. Control animals received 0.9% NaCI solution alone. All data are modified after Keil et al. (2006). (A) Dissociated brain cells were isolated and MMP was detected. The MMP was significantly reduced in old animals (22 months) and protected by Piracetam. Data are expressed as mean ± SEM (n = 6–8) *p \u003c 0.05 piracetam treated old animals vs. aged controls. (B,C) Effects of aging and treatment with piracetam on SOD, and GPx in young and old animals. Activities of antioxidant enzymes are increased in aged mice. Treatment with piracetam reduces the enzyme activities significantly in old mice. Data are expressed as mean ± SEM (n = 7). *p \u003c 0.05 piracetam treated old animals vs. aged controls."}

{"project":"2_test","denotations":[{"id":"20877425-16520237-38148022","span":{"begin":351,"end":355},"obj":"16520237"}],"text":"Figure 1 Piracetam reduces measures of mitochondrial dysfunction in NMRI mice – higher sensitivity in aged mice 2–3 months old and 22–24 months old NMRI mice were treated for 14 days with 0.5 g piracetam/kg in 0.9% NaCI solution p.o. once daily for 2 weeks. Control animals received 0.9% NaCI solution alone. All data are modified after Keil et al. (2006). (A) Dissociated brain cells were isolated and MMP was detected. The MMP was significantly reduced in old animals (22 months) and protected by Piracetam. Data are expressed as mean ± SEM (n = 6–8) *p \u003c 0.05 piracetam treated old animals vs. aged controls. (B,C) Effects of aging and treatment with piracetam on SOD, and GPx in young and old animals. Activities of antioxidant enzymes are increased in aged mice. Treatment with piracetam reduces the enzyme activities significantly in old mice. Data are expressed as mean ± SEM (n = 7). *p \u003c 0.05 piracetam treated old animals vs. aged controls."}