Thus, the post-ischemic increase in neurogenesis was large but transient. Double-labeling experiments demonstrated expression pattern of immature neuronal marker (DCX/BrdU) and mature neuronal marker (CaBP/BrdU) to be similar in control and ischemic groups (Table 2). Considering large absolute numbers of neuronal precursors generated after ischemia this represents substantial net addition of potential new neurons in ischemic animals.