In the experiments we used a threshold to adjust the average number of CAD regions per image that could be activated. On average, there were two false positives per normal image. In clinical practice the operating point of prompting systems for masses in mammography are often set to a level near 0.5 false positives per image. We used more regions, because it was thought that in the interactive system more false positives would be tolerable. Many of them are never activated, and if they are activated they are perceived very differently than traditional prompts. The radiologists queried far fewer false-positive CAD regions than the non-radiologists which may indicate they are more confident in their reading.