Ultrasound applications are widely and routinely used in neuromuscular disorders in terms of assessment of changes in muscle morphology (atrophy, hypertrophy, changes in muscle architecture). In particular it is a useful screening tool during the initial diagnostic phase, especially in children. Depending on the disease entity, the sensitivity of detecting dystrophic changes ranges from 25% in non-dystrophic myopathies up to 100% in dystrophic myopathies (Duchenne muscular dystrophy) [10, 19, 20]. The detection of pathological changes can be helpful in guiding muscle biopsy, and the description of the muscle involvement pattern might help in the differential diagnosis [10, 21].