Table 3 Comparison of perfusion parameters between affected and normal cerebral parenchyma. Values are expressed as mean ± SD Histopathological K Trans p a CBV p a CBF p a subgroup (p) (ml/100 ml/min) (ml/100 ml) (ml/100 ml/min) Lesion Control Lesion Control Lesion Control Low-grade gliomas (4) 3.73 ± 5.35 1.66 ± 1.79 0.25 3.28 ± 0.46 2.96 ± 0.42 0.38 62.28 ± 16.91 65.80 ± 5.50 0.88 High-grade gliomas (31) 6.58 ± 3.68 0.86 ± 0.79 <0.0001 6.03 ± 2.18 3.22 ± 0.42 <0.0001 97.63 ± 41.17 64.45 ± 7.84 0.0002 Lymphomas (8) 11.96 ± 10.66 1.31 ± 1.79 0.0078 3.79 ± 1.95 3.14 ± 0.42 0.55 82.79 ± 40.03 64.87 ± 9.61 0.25 a p compared with healthy parenchyma values (control) using Wilcoxon test