However, the TLR4 mRNA after ICH significantly increased starting from 6 hours after ICH (P <.05), peaked on 3 days after ICH (P < .05), and then decreased on 7 days after ICH, but still maintained at a higher level compared with saline control (P < .05). #: compared with saline control, P < .05; *: compared with 6 hours after ICH, P < .05.