A separate grid control system running on the Bioinformatics Core Facility server at the University of Texas Health Science Center at San Antonio manages all submissions and queuing of analysis requests to remote clusters using the Globus (http://www.globus.org) and TIGRE (http://www.hipcat.net/Projects/tigre) toolkits and by communicating with all major queuing systems such as PBS (http://www.openpbs.org) and Sun GridEngine (http://gridengine.sunsource.net). Analysis results are committed back to the LIMS where they can be retrieved for further processing and visualized with UltraScan. The grid control module is written in Perl and communicates with selected remote clusters to run MPI jobs (http://www.open-mpi.org/) and to coordinate PBS job queuing (Brookes and Demeler 2008).