Vaccines (reviewed by Subbarao and Luke, 2007, Chen et al., 2008, Lalor et al., 2008, Mahmood et al., 2008) and a number antiviral compounds (Malakhov et al., 2006, Govorkova et al., 2007, Boltz et al., 2008b, Yun et al., 2008) have been tested in ferrets infected with H5N1 viruses very often have verified findings in mice (Malakhov et al., 2006, Govorkova et al., 2007, Boltz et al., 2008b, Yun et al., 2008).