Table 3 Summary of currently available animal models for studying severe seasonal influenza pneumonia.
Virus Animal Model References
Influenza A H3N2 strains Mouse (BALB/c) Reviewed by Sidwell and Smee (2000)
A/Shangdong/09/93
A/Victoria/3/79



Influenza B strains
B/HongKong/5/72
B/Lee/40



B/Sichuan/379/99 BALB/c Smee et al. (2006)
Influenza A H1N1 strains BALB/c Smee et al. (2008)
A/WSN/33 (H1N1) virus containing the HA gene of A/New Caledonia/20/99



A/New Caledonia/20/99 BALB/c Smee et al. (2006)



Influenza A strains
A/Charlottesville/31/95 (H1N1) Ferret Smee et al. (2008)



A/USSR/90/77 (H1N1) Ferret Svitek et al. (2008)
A/Port Chalmers/1/73 (H3N2)



Influenza A H3N2 A/Wuhan/359/95 Cotton Rat Ottolini et al. (2005), Review by Eichelberger (2007)